Publications by authors named "Leon van Gurp"

15Publications

A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas.

Development 2019 06 24;146(12). Epub 2019 Jun 24.

Hubrecht Institute/KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584CT Utrecht, The Netherlands

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June 2019

Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.

Nature 2019 03 13;567(7746):43-48. Epub 2019 Feb 13.

Department of Genetic Medicine and Development, iGE3 and Centre Facultaire du Diabète, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

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March 2019

A Single-Cell Transcriptome Atlas of the Human Pancreas.

Cell Syst 2016 10 29;3(4):385-394.e3. Epub 2016 Sep 29.

Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Cancer Genomics Netherlands, 3584 CT Utrecht, the Netherlands. Electronic address:

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October 2016

Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.

Dev Biol 2012 Sep 9;369(1):91-100. Epub 2012 Jun 9.

Departments of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.

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September 2012

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

PLoS One 2011 Apr 29;6(4):e19357. Epub 2011 Apr 29.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands.

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April 2011

An ENU-induced point mutation in the mouse Btaf1 gene causes post-gastrulation embryonic lethality and protein instability.

Mech Dev 2011 May-Jun;128(5-6):279-88. Epub 2011 Mar 16.

Hubrecht Institute, KNAW and University Medical Center Utrecht, Uppsalalaan, Netherlands.

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October 2011

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.

Gut 2011 Sep 9;60(9):1204-12. Epub 2011 Feb 9.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Centre, room L-63, 's Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

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September 2011

Duodenal pain and spinal morphine induce conditioned taste aversion in rats.

Physiol Behav 2007 Jun 16;91(2-3):310-7. Epub 2007 Mar 16.

Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands.

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June 2007

Individual reactivity to the open-field predicts the expression of cardiovascular and behavioural sensitisation to novel stress.

Behav Brain Res 2006 Nov 22;175(1):9-17. Epub 2006 Aug 22.

Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands.

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November 2006

Individual reactivity to the open-field predicts the expression of stress-induced behavioural and somatic pain sensitisation.

Behav Brain Res 2006 Nov 22;174(1):112-8. Epub 2006 Aug 22.

Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands.

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November 2006