Leon A Simons

Leon A Simons

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Leon A Simons

Leon A Simons

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An updated review of lipid-modifying therapy.

Authors:
Leon A Simons

Med J Aust 2019 Jul 21;211(2):87-92. Epub 2019 Apr 21.

UNSW Sydney, Sydney, NSW.

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http://dx.doi.org/10.5694/mja2.50142DOI Listing
July 2019

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.

Authors:
Lisa Pennells Stephen Kaptoge Angela Wood Mike Sweeting Xiaohui Zhao Ian White Stephen Burgess Peter Willeit Thomas Bolton Karel G M Moons Yvonne T van der Schouw Randi Selmer Kay-Tee Khaw Vilmundur Gudnason Gerd Assmann Philippe Amouyel Veikko Salomaa Mika Kivimaki Børge G Nordestgaard Michael J Blaha Lewis H Kuller Hermann Brenner Richard F Gillum Christa Meisinger Ian Ford Matthew W Knuiman Annika Rosengren Debbie A Lawlor Henry Völzke Cyrus Cooper Alejandro Marín Ibañez Edoardo Casiglia Jussi Kauhanen Jackie A Cooper Beatriz Rodriguez Johan Sundström Elizabeth Barrett-Connor Rachel Dankner Paul J Nietert Karina W Davidson Robert B Wallace Dan G Blazer Cecilia Björkelund Chiara Donfrancesco Harlan M Krumholz Aulikki Nissinen Barry R Davis Sean Coady Peter H Whincup Torben Jørgensen Pierre Ducimetiere Maurizio Trevisan Gunnar Engström Carlos J Crespo Tom W Meade Marjolein Visser Daan Kromhout Stefan Kiechl Makoto Daimon Jackie F Price Agustin Gómez de la Cámara J Wouter Jukema Benoît Lamarche Altan Onat Leon A Simons Maryam Kavousi Yoav Ben-Shlomo John Gallacher Jacqueline M Dekker Hisatomi Arima Nawar Shara Robert W Tipping Ronan Roussel Eric J Brunner Wolfgang Koenig Masaru Sakurai Jelena Pavlovic Ron T Gansevoort Dorothea Nagel Uri Goldbourt Elizabeth L M Barr Luigi Palmieri Inger Njølstad Shinichi Sato W M Monique Verschuren Cherian V Varghese Ian Graham Oyere Onuma Philip Greenland Mark Woodward Majid Ezzati Bruce M Psaty Naveed Sattar Rod Jackson Paul M Ridker Nancy R Cook Ralph B D'Agostino Simon G Thompson John Danesh Emanuele Di Angelantonio

Eur Heart J 2019 02;40(7):621-631

Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, UK.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/eurheartj/ehy653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374687PMC
February 2019

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.

Authors:
Angela M Wood Stephen Kaptoge Adam S Butterworth Peter Willeit Samantha Warnakula Thomas Bolton Ellie Paige Dirk S Paul Michael Sweeting Stephen Burgess Steven Bell William Astle David Stevens Albert Koulman Randi M Selmer W M Monique Verschuren Shinichi Sato Inger Njølstad Mark Woodward Veikko Salomaa Børge G Nordestgaard Bu B Yeap Astrid Fletcher Olle Melander Lewis H Kuller Beverley Balkau Michael Marmot Wolfgang Koenig Edoardo Casiglia Cyrus Cooper Volker Arndt Oscar H Franco Patrik Wennberg John Gallacher Agustín Gómez de la Cámara Henry Völzke Christina C Dahm Caroline E Dale Manuela M Bergmann Carlos J Crespo Yvonne T van der Schouw Rudolf Kaaks Leon A Simons Pagona Lagiou Josje D Schoufour Jolanda M A Boer Timothy J Key Beatriz Rodriguez Conchi Moreno-Iribas Karina W Davidson James O Taylor Carlotta Sacerdote Robert B Wallace J Ramon Quiros Rosario Tumino Dan G Blazer Allan Linneberg Makoto Daimon Salvatore Panico Barbara Howard Guri Skeie Timo Strandberg Elisabete Weiderpass Paul J Nietert Bruce M Psaty Daan Kromhout Elena Salamanca-Fernandez Stefan Kiechl Harlan M Krumholz Sara Grioni Domenico Palli José M Huerta Jackie Price Johan Sundström Larraitz Arriola Hisatomi Arima Ruth C Travis Demosthenes B Panagiotakos Anna Karakatsani Antonia Trichopoulou Tilman Kühn Diederick E Grobbee Elizabeth Barrett-Connor Natasja van Schoor Heiner Boeing Kim Overvad Jussi Kauhanen Nick Wareham Claudia Langenberg Nita Forouhi Maria Wennberg Jean-Pierre Després Mary Cushman Jackie A Cooper Carlos J Rodriguez Masaru Sakurai Jonathan E Shaw Matthew Knuiman Trudy Voortman Christa Meisinger Anne Tjønneland Hermann Brenner Luigi Palmieri Jean Dallongeville Eric J Brunner Gerd Assmann Maurizio Trevisan Richard F Gillum Ian Ford Naveed Sattar Mariana Lazo Simon G Thompson Pietro Ferrari David A Leon George Davey Smith Richard Peto Rod Jackson Emily Banks Emanuele Di Angelantonio John Danesh

Lancet 2018 04;391(10129):1513-1523

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)30134-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899998PMC
April 2018

LDL-cholesterol Predicts a First CHD Event in Senior Citizens, Especially So in Those With Elevated Lipoprotein(a): Dubbo Study of the Elderly.

Heart Lung Circ 2018 Mar 17;27(3):386-389. Epub 2017 May 17.

National Seniors Australia, Canberra, ACT, Australia.

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http://dx.doi.org/10.1016/j.hlc.2017.04.012DOI Listing
March 2018

Long-term persistence with single-pill, fixed-dose combination therapy versus two pills of amlodipine and perindopril for hypertension: Australian experience.

Curr Med Res Opin 2017 10 24;33(10):1783-1787. Epub 2017 Aug 24.

c UNSW Sydney, St Vincent's Clinical School , Darlinghurst , NSW , Australia.

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http://dx.doi.org/10.1080/03007995.2017.1367275DOI Listing
October 2017

Medium- to long-term persistence with non-vitamin-K oral anticoagulants in patients with atrial fibrillation: Australian experience.

Curr Med Res Opin 2017 07 10;33(7):1337-1341. Epub 2017 May 10.

e University of Queensland, Wesley Medical Centre , Auchenflower , QLD , Australia.

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http://dx.doi.org/10.1080/03007995.2017.1321535DOI Listing
July 2017

Hypertension, antihypertensive treatment and cancer incidence and mortality: a pooled collaborative analysis of 12 Australian and New Zealand cohorts.

J Hypertens 2016 Jan;34(1):149-55

aDepartment of Clinical Diabetes and Epidemiology, Baker IDI Heart and Diabetes Institute bDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria cCenter for Research on Ageing, Health and Wellbeing, Research School of Population Health, the Australian National University, Canberra, Australian Capital Territory dThe Health Observatory Discipline of Medicine, the University of Adelaide, Adelaide, South Australia, Australia eCenter for Research in Epidemiology and Population Health, INSERM, France fSchool of Population Health, the University of Western Australia gSchool of Medicine and Pharmacology, the University of Western Australia, Western Australia, Crawley, hSchool of Public Health, the University of Queensland, Queensland, Brisbane iCancer Epidemiology Center, Cancer Council Victoria, Melbourne, Victoria jPopulation Research and Outcome Studies, the University of Adelaide kSchool of Psychology and Flinders Center for Ageing Studies, Flinders University, Adelaide, South Australia lWestmead Millennium Institute, the University of Sydney, Sydney, New South Wales mIMPACT Strategic Research Center School of Medicine, Deakin University, Geelong, Victoria nDepartment of Medicine, NorthWest Academic Center, the University of Melbourne, Melbourne, St Albans oSchool of Public Health, Curtin University, Western Australia, Perth pMacarthur Clinical School, University of Western Sydney, Western Sydney, Campbelltown qDepartment of Rural Health, the University of Melbourne, Melbourne, Shepparton rUNSW Australia Lipid Research Department, St Vincent's Hospital, Sydney, New South Wales sSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria tThe George Institute for Global Health, the University of Sydney, Sydney, New South Wales, Australia uNuffield Department of Population Health, the George Institute for Global Health, University of Oxford, Oxford, UK *Joint senior authorship.

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http://dx.doi.org/10.1097/HJH.0000000000000770DOI Listing
January 2016

Association of Cardiometabolic Multimorbidity With Mortality.

JAMA 2015 07;314(1):52-60

University of Cambridge, Cambridge, England.

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http://dx.doi.org/10.1001/jama.2015.7008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664176PMC
July 2015

Prediction of cardiovascular and all-cause mortality at 10 years in the hypertensive aged population.

Am J Hypertens 2015 May 14;28(5):649-56. Epub 2014 Nov 14.

Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia;

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http://dx.doi.org/10.1093/ajh/hpu213DOI Listing
May 2015

Are high coronary risk patients missing out on lipid-lowering drugs in Australia?

Med J Aust 2014 Aug;201(4):213-6

Prospection Pty Ltd, Sydney, NSW, Australia.

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August 2014

Glycated hemoglobin measurement and prediction of cardiovascular disease.

JAMA 2014 Mar;311(12):1225-33

University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1001/jama.2014.1873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386007PMC
March 2014

Persistence on warfarin in patients with atrial fibrillation: experience in Australia 2006-2009.

Aust Fam Physician 2013 Sep;42(9):659-61

MD, FRACP, is Associate Professor of Medicine and Director, Lipid Research Department, University of New South Wales, St Vincent's Hospital, New South Wales.

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September 2013

Impact of loneliness and living alone.

JAMA Intern Med 2013 Feb;173(4):322-3

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http://dx.doi.org/10.1001/jamainternmed.2013.1611DOI Listing
February 2013

Childbearing history and late-life mortality: the Dubbo study of Australian elderly.

Age Ageing 2012 Jul 29;41(4):523-8. Epub 2012 Mar 29.

Lipid Department, St Vincent's Hospital, University of NSW, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1093/ageing/afs016DOI Listing
July 2012

A comparison of risk factors for coronary heart disease and ischaemic stroke.

Heart Lung Circ 2012 Mar 23;21(3):198-9. Epub 2011 Dec 23.

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http://dx.doi.org/10.1016/j.hlc.2011.11.007DOI Listing
March 2012

Persistence with a single pill versus two pills of amlodipine and atorvastatin: the Australian experience, 2006-2010.

Med J Aust 2011 Aug;195(3):134-7

St Vincent's Hospital, University of New South Wales, Sydney, NSW, Australia.

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August 2011

Long term persistence with statin therapy -- experience in Australia 2006-2010.

Aust Fam Physician 2011 May;40(5):319-22

University of New South Wales, St Vincent's Hospital, New South Wales.

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May 2011

Is prediction of cardiovascular disease and all-cause mortality genuinely driven by the metabolic syndrome, and independently from its component variables? The Dubbo study.

Heart Lung Circ 2011 Apr 24;20(4):214-9. Epub 2011 Feb 24.

University of NSW, Lipid Research Department, St Vincent's Hospital, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.hlc.2010.12.005DOI Listing
April 2011

Generic substitution of commonly used medications: Australia-wide experience, 2007-2008.

Med J Aust 2010 Apr;192(7):370-3

Solvay Pharmaceuticals, Sydney, NSW, Australia.

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April 2010

A comparison of risk factors for coronary heart disease and ischaemic stroke: the Dubbo study of Australian elderly.

Heart Lung Circ 2009 Oct 3;18(5):330-3. Epub 2009 Aug 3.

Lipid Research Department, University of NSW, St Vincent's Hospital, Sydney, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.hlc.2009.05.001DOI Listing
October 2009

Persistence with antihypertensive medication: Australia-wide experience, 2004-2006.

Med J Aust 2008 Feb;188(4):224-7

Lipid Research Department, University of New South Wales, St Vincent's Hospital, Sydney, NSW, Australia.

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February 2008

Private lives and public programs: an Australian longitudinal study of the elderly.

J Aging Soc Policy 2007 ;19(4):87-103

Victoria University, Melbourne, Australia.

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http://dx.doi.org/10.1300/J031v19n04_05DOI Listing
December 2007

Delaying dementia and nursing home placement: the Dubbo study of elderly Australians over a 14-year follow-up.

Ann N Y Acad Sci 2007 Oct;1114:121-9

Victoria University, PO Box 14428, Melbourne, Victoria 8001, Australia.

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http://dx.doi.org/10.1196/annals.1396.049DOI Listing
October 2007

Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? The Dubbo Study.

Med J Aust 2007 Apr;186(8):400-3

University of New South Wales Lipid Research Department, St Vincent's Hospital, Sydney, NSW.

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April 2007

Ezetimibe added to statin therapy (EASY study) - an evaluation by Australian general practitioners.

Aust Fam Physician 2007 Jan-Feb;36(1-2):90-2, 96

University of New South Wales, Lipid Research Department, St Vincent's Hospital, Sydney, New South Wales, Australia.

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March 2007

Effect of Lactobacillus fermentum on serum lipids in subjects with elevated serum cholesterol.

Nutr Metab Cardiovasc Dis 2006 Dec 18;16(8):531-5. Epub 2006 Jan 18.

School of Medicine, University of NSW, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.numecd.2005.10.009DOI Listing
December 2006

Lifestyle factors and risk of dementia: Dubbo Study of the elderly.

Med J Aust 2006 Jan;184(2):68-70

Lipid Research Department, St Vincent's Hospital, Darlinghurst, NSW 2010, Australia.

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January 2006

Impact of smoking, diabetes and hypertension on survival time in the elderly: the Dubbo Study.

Med J Aust 2005 Mar;182(5):219-22

Lipid Research Department, University of New South Wales, St Vincent's Hospital, Darlinghurst, NSW 2010, Australia.

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March 2005

Lipid-modifying drugs.

Med J Aust 2005 Mar;182(6):286-9

University of South Wales, Lipid Research Department, St Vincent's Hospital, Darlinghurst, NSW 2010, Australia.

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March 2005

Risk functions for prediction of cardiovascular disease in elderly Australians: the Dubbo Study.

Med J Aust 2003 Feb;178(3):113-6

University of New South Wales Lipid Research Department, St Vincent's Hospital, Darlinghurst, NSW 2010, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133925PMC
February 2003

Additive effect of plant sterol-ester margarine and cerivastatin in lowering low-density lipoprotein cholesterol in primary hypercholesterolemia.

Authors:
Leon A Simons

Am J Cardiol 2002 Oct;90(7):737-40

University of New South Wales Lipid Research Department, St Vincent's Hospital, Sydney, Australia.

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http://dx.doi.org/10.1016/s0002-9149(02)02600-0DOI Listing
October 2002

Risk factors for acute myocardial infarction in the elderly (the Dubbo study).

Am J Cardiol 2002 Jan;89(1):69-72

University of New South Wales Lipid Research Department, St Vincent's Hospital, Sydney, Australia.

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http://dx.doi.org/10.1016/s0002-9149(01)02168-3DOI Listing
January 2002