Lenore J Launer

Lenore J Launer

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Lenore J Launer

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Microstructural white matter changes preceding white matter hyperintensities in migraine.

Neurology 2019 Aug 11;93(7):e688-e694. Epub 2019 Jul 11.

From the Departments of Radiology (E.B.A., I.H.P.-M., J.M., B.v.L., M.A.v.B., M.C.K.) and Neurology (H.K.) and Laboratory for Clinical and Experimental Image Processing, Department of Radiology (J.M., B.v.L.), Leiden University Medical Center; Department of Neurology (H.K., G.M.T., M.D.F.), Haga Hospital, The Hague, the Netherlands; Laboratory of Epidemiology and Population Sciences (L.J.L.), National Institute on Aging, Bethesda, MD; and Department of Radiology (P.A.M.H.), Maastricht University Medical Center, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000007940DOI Listing
August 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 Aug 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Aug 15. Epub 2019 Aug 15.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
August 2019

Cigarette smoking and cerebral blood flow in a cohort of middle-aged adults.

J Cereb Blood Flow Metab 2019 Jul 22;39(7):1247-1257. Epub 2018 Jan 22.

1 Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/0271678X18754973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668508PMC
July 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-019-0449-0DOI Listing
July 2019

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.

Authors:
Paul S de Vries Michael R Brown Amy R Bentley Yun J Sung Thomas W Winkler Ioanna Ntalla Karen Schwander Aldi T Kraja Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Xuan Deng Rajkumar Dorajoo Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Evangelos Evangelou Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Joseph H Lee Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Muhammad Riaz M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Yajuan Wang Erin B Ware Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Christie Ballantyne Eric Boerwinkle Ulrich Broeckel Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Ulf de Faire Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Jingzhong Ding Anna F Dominiczak Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul Virginia Fisher Terrence Forrester Oscar H Franco Yechiel Friedlander Mohsen Ghanbari Franco Giulianini Hans J Grabe Megan L Grove C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson Barbara V Howard M Arfan Ikram David R Jacobs Craig Johnson Jost Bruno Jonas Candace M Kammerer Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Heikki A Koistinen Ivana Kolcic Charles Kooperberg Jose E Krieger Steve B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Rozenn N Lemaitre Yize Li Jingjing Liang Jianjun Liu Kiang Liu Marie Loh Tin Louie Reedik Mägi Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Thomas H Mosley Kenneth J Mukamal Mike A Nalls Matthias Nauck Christopher P Nelson Nona Sotoodehnia Jeff R O'Connell Nicholette D Palmer Raha Pazoki Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Leslie J Raffel Olli T Raitakari Alex P Reiner Treva K Rice Stephen S Rich Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Nicholas Tan Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Diana van Heemst Dragana Vuckovic Melanie Waldenberger Lihua Wang Yujie Wang Zhe Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Markku Laakso Karin Leander Terho Lehtimäki Patrik K E Magnusson Brenda Penninx Alexandre C Pereira Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Wei Zheng Paul Elliott Kari E North Claude Bouchard Michele K Evans Vilmundur Gudnason Ching-Ti Liu Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Sharon L R Kardia Xiaofeng Zhu Charles N Rotimi Dennis O Mook-Kanamori Myriam Fornage Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Jingmin Liu Jerome I Rotter W James Gauderman Michael A Province Patricia B Munroe Kenneth Rice Daniel I Chasman L Adrienne Cupples Dabeeru C Rao Alanna C Morrison

Am J Epidemiol 2019 Jun;188(6):1033-1054

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas.

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https://academic.oup.com/aje/advance-article/doi/10.1093/aje
Publisher Site
http://dx.doi.org/10.1093/aje/kwz005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545280PMC
June 2019

Gut Microbiota Composition and Blood Pressure.

Hypertension 2019 May;73(5):998-1006

Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC (A.L., K.A.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458072PMC
May 2019

Depressive Symptomatology, Racial Discrimination Experience, and Brain Tissue Volumes Observed on Magnetic Resonance Imaging.

Am J Epidemiol 2019 Apr;188(4):656-663

the Neuroepidemiology Section, National Institute on Aging, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1093/aje/kwy282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438808PMC
April 2019

Structural covariability hubs in old age.

Neuroimage 2019 04 19;189:307-315. Epub 2019 Jan 19.

Department of Neuroscience, Karolinska Institutet, S-17177, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.neuroimage.2019.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438381PMC
April 2019

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Authors:
Amy R Bentley Yun J Sung Michael R Brown Thomas W Winkler Aldi T Kraja Ioanna Ntalla Karen Schwander Daniel I Chasman Elise Lim Xuan Deng Xiuqing Guo Jingmin Liu Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Jenna Baker Guanjie Chen Hugues Aschard Traci M Bartz Jingzhong Ding Rajkumar Dorajoo Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Wei Zhao Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Yi-Jen Hung Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Bram Prins Muhammad Riaz Antonietta Robino M Abdullah Said Nicole Schupf Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Tzung-Dau Wang Yajuan Wang Erin B Ware Wanqing Wen Yong-Bing Xiang Lisa R Yanek Weihua Zhang Jing Hua Zhao Adebowale Adeyemo Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Zorayr Arzumanyan Tin Aung Christie Ballantyne R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Ulrich Broeckel Morris Brown Brian E Cade Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen Kaare Christensen Maria Pina Concas John M Connell Lisa de Las Fuentes H Janaka de Silva Paul S de Vries Ayo Doumatey Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul James S Floyd Nita G Forouhi Terrence Forrester Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Sina A Gharib Bruna Gigante Franco Giulianini Hans J Grabe C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson M Arfan Ikram Yucheng Jia Roby Joehanes Craig Johnson Jost Bruno Jonas Anne E Justice Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Ivana Kolcic Charles Kooperberg Jose E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Jingjing Liang Shiow Lin Ching-Ti Liu Jianjun Liu Kiang Liu Marie Loh Kurt K Lohman Tin Louie Anna Luzzi Reedik Mägi Anubha Mahajan Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Andrew P Morris Alison D Murray Mike A Nalls Matthias Nauck Christopher P Nelson Kari E North Jeffrey R O'Connell Nicholette D Palmer George J Papanicolau Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Olli T Raitakari Alex P Reiner Frida Renström Treva K Rice Stephen S Rich Jennifer G Robinson Lynda M Rose Frits R Rosendaal Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Henning Tiemeier Stephen T Turner André G Uitterlinden Diana van Heemst Melanie Waldenberger Heming Wang Lan Wang Lihua Wang Wen Bin Wei Christine A Williams Gregory Wilson Mary K Wojczynski Jie Yao Kristin Young Caizheng Yu Jian-Min Yuan Jie Zhou Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Richard S Cooper Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Jyh-Ming Jimmy Juang Yoichiro Kamatani Candace M Kammerer Norihiro Kato Jaspal S Kooner Markku Laakso Cathy C Laurie I-Te Lee Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Alexandre C Pereira Rainer Rauramaa Susan Redline Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Jun-Sing Wang Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Eleftheria Zeggini Wei Zheng Claude Bouchard Michele K Evans Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Dennis O Mook-Kanamori Myriam Fornage Michael A Province Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Nora Franceschini Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Kenneth Rice Patricia B Munroe Alanna C Morrison Dabeeru C Rao Charles N Rotimi L Adrienne Cupples

Nat Genet 2019 04 29;51(4):636-648. Epub 2019 Mar 29.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-019-0378-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467258PMC
April 2019

Left Atrial Mechanical Function and Incident Ischemic Cerebrovascular Events Independent of AF: Insights From the MESA Study.

JACC Cardiovasc Imaging 2019 Apr 17. Epub 2019 Apr 17.

Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jcmg.2019.02.021DOI Listing
April 2019

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Authors:
Yun Ju Sung Lisa de Las Fuentes Thomas W Winkler Daniel I Chasman Amy R Bentley Aldi T Kraja Ioanna Ntalla Helen R Warren Xiuqing Guo Karen Schwander Alisa K Manning Michael R Brown Hugues Aschard Mary F Feitosa Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Tuomas O Kilpeläinen Melissa A Richard Stella Aslibekyan Traci M Bartz Rajkumar Dorajoo Changwei Li Yongmei Liu Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Candace M Kammerer Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Colin A McKenzie Christopher P Nelson Raymond Noordam Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Robert J Waken Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan E Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Brian Cade Archie Campbell Mickaël Canouil Aravinda Chakravarti Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante C Charles Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Albert Hofman Barbara V Howard Steven C Hunt Marguerite R Irvin Yucheng Jia Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Charles B Kooperberg Jose E Krieger Michiaki Kubo Zoltan Kutalik Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Joseph H Lee Benjamin Lehne Daniel Levy Cora E Lewis Yize Li Sing Hui Lim Ching-Ti Liu Jianjun Liu Jingmin Liu Yeheng Liu Marie Loh Kurt K Lohman Tin Louie Reedik Mägi Koichi Matsuda Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Thomas H Mosley Mike A Nalls Ubaydah Nasri Jeff R O'Connell Adesola Ogunniyi Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David Porteous Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Mario Sims Colleen M Sitlani Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Gregory Wilson Mary K Wojczynski Yong-Bing Xiang Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen David R Weir Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost Bruno Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Albertine J Oldehinkel Alexandre C Pereira Thomas Perls Rainer Rauramaa Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins Ananda R Wickremasinghe Tangchun Wu Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason James Hixson Sharon L R Kardia Stephen B Kritchevsky Bruce M Psaty Rob M van Dam Donna K Arnett Dennis O Mook-Kanamori Myriam Fornage Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Charles N Rotimi Laura J Bierut Xiaofeng Zhu L Adrienne Cupples Michael A Province Jerome I Rotter Paul W Franks Kenneth Rice Paul Elliott Mark J Caulfield W James Gauderman Patricia B Munroe Dabeeru C Rao Alanna C Morrison

Hum Mol Genet 2019 Apr 10. Epub 2019 Apr 10.

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.1093/hmg/ddz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644157PMC
April 2019

Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis.

Neurology 2019 Mar 1;92(10):e1086-e1097. Epub 2019 Feb 1.

From the Stroke Research Center, Department of Brain Repair & Rehabilitation, Institute of Neurology (Y.Y., D.W., A.C., D.J.W.), and Department of Statistical Science (G.A.), UCL, London, UK; Division of Neurology (Y.Y., H.H.), Department of Internal Medicine, Saga University Faculty of Medicine, Japan; Department of Neurology (A.B., S.R.P., J.R.R., S.S., P.A.W.), Boston University and the NHLBI's Framingham Heart Study; Department of Biostatistics (A.B., S.R.P.), Boston University, MA; Department of Radiology (M.A.v.B.), Leiden University Medical Center, the Netherlands; Department of Neurology (C.D.), University of California Davis; Department of Neurology (D.D.), Huashan Hospital, Fudan University, Shanghai, China; Icelandic Heart Association (V.G.), Kopavogur; University of Iceland (V.G.), Reykjavik; Department of Neurosurgery (T.I.), Kushiro City General Hospital; Faculty of Collaborative Regional Innovation (K.K.), Ehime University, Matsuyama, Japan; Department of Neurology (H.-M.K.), SMG-SNU Boramae Medical Center, Seoul, Republic of Korea; Intramural Research Program (L.J.L.), National Institute on Aging, Bethesda, MD; Therese Pei Fong Chow Research Center for Prevention of Dementia (V.M., Z.W., Y.X.), Department of Medicine and Therapeutics, The Chinese University of Hong Kong, China; Stroke and Aging Research Group, Department of Medicine, School of Clinical Science at Monash Health (T.P., V.S.), and Department of Medicine, Peninsula Health and Clinical School, Central Clinical School (V.S.), Monash University, Melbourne, Australia; Center for Emotional and Behavioral Disorders (Y. Takashima), Hizen Psychiatric Center, Saga, Japan; Department of Diagnostic Radiology and Nuclear Medicine (Y. Tsushima), Gunma University Graduate School of Medicine; Research Program for Diagnostic and Molecular Imaging (Y. Tsushima), Division of Integrated Oncology Research, Gunma University Initiative for Advanced Research, Maebashi; and Department of Neurology (S.Y.), Faculty of Medicine, Shimane University, Izumo, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442016PMC
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults.

Eur Heart J 2019 Feb;40(6):529-538

Department of Health and Human Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room B1D416, MSC 1061, 10 Center Dr., Bethesda, MD, USA.

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http://dx.doi.org/10.1093/eurheartj/ehy713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657269PMC
February 2019

Cigarette smoking and gray matter brain volumes in middle age adults: the CARDIA Brain MRI sub-study.

Transl Psychiatry 2019 02 11;9(1):78. Epub 2019 Feb 11.

Laboratory of Epidemiology and Population Science, National Institute on Aging, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41398-019-0401-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370765PMC
February 2019

Carotid intima-media thickness and markers of brain health in a bi-racial middle-aged cohort: CARDIA Brain MRI Sub-study.

J Gerontol A Biol Sci Med Sci 2019 Feb 23. Epub 2019 Feb 23.

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, United States of America.

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http://dx.doi.org/10.1093/gerona/glz039DOI Listing
February 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

PLoS One 2018 18;13(6):e0198166. Epub 2018 Jun 18.

The Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005576PMC
January 2019

Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms.

Alzheimers Dement 2019 01 19;15(1):65-75. Epub 2018 Sep 19.

Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Gerontology Research Unit, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435328PMC
January 2019

Statistics on the burden of dementia: need for stronger data.

Authors:
Lenore J Launer

Lancet Neurol 2019 Jan 26;18(1):25-27. Epub 2018 Nov 26.

Neuroepidemiology Section, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30456-3DOI Listing
January 2019

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Circulation 2019 Jan;139(5):620-635

Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438386PMC
January 2019

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Authors:
Ganesh Chauhan Hieab H H Adams Claudia L Satizabal Joshua C Bis Alexander Teumer Muralidharan Sargurupremraj Edith Hofer Stella Trompet Saima Hilal Albert Vernon Smith Xueqiu Jian Rainer Malik Matthew Traylor Sara L Pulit Philippe Amouyel Bernard Mazoyer Yi-Cheng Zhu Sara Kaffashian Sabrina Schilling Gary W Beecham Thomas J Montine Gerard D Schellenberg Olafur Kjartansson Vilmundur Guðnason David S Knopman Michael E Griswold B Gwen Windham Rebecca F Gottesman Thomas H Mosley Reinhold Schmidt Yasaman Saba Helena Schmidt Fumihiko Takeuchi Shuhei Yamaguchi Toru Nabika Norihiro Kato Kumar B Rajan Neelum T Aggarwal Philip L De Jager Denis A Evans Bruce M Psaty Jerome I Rotter Kenneth Rice Oscar L Lopez Jiemin Liao Christopher Chen Ching-Yu Cheng Tien Y Wong Mohammad K Ikram Sven J van der Lee Najaf Amin Vincent Chouraki Anita L DeStefano Hugo J Aparicio Jose R Romero Pauline Maillard Charles DeCarli Joanna M Wardlaw Maria Del C Valdés Hernández Michelle Luciano David Liewald Ian J Deary John M Starr Mark E Bastin Susana Muñoz Maniega P Eline Slagboom Marian Beekman Joris Deelen Hae-Won Uh Robin Lemmens Henry Brodaty Margaret J Wright David Ames Giorgio B Boncoraglio Jemma C Hopewell Ashley H Beecham Susan H Blanton Clinton B Wright Ralph L Sacco Wei Wen Anbupalam Thalamuthu Nicola J Armstrong Elizabeth Chong Peter R Schofield John B Kwok Jeroen van der Grond David J Stott Ian Ford J Wouter Jukema Meike W Vernooij Albert Hofman André G Uitterlinden Aad van der Lugt Katharina Wittfeld Hans J Grabe Norbert Hosten Bettina von Sarnowski Uwe Völker Christopher Levi Jordi Jimenez-Conde Pankaj Sharma Cathie L M Sudlow Jonathan Rosand Daniel Woo John W Cole James F Meschia Agnieszka Slowik Vincent Thijs Arne Lindgren Olle Melander Raji P Grewal Tatjana Rundek Kathy Rexrode Peter M Rothwell Donna K Arnett Christina Jern Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Quenna Wong Braxton D Mitchell Stephen S Rich Patrick F McArdle Mirjam I Geerlings Yolanda van der Graaf Paul I W de Bakker Folkert W Asselbergs Velandai Srikanth Russell Thomson Rebekah McWhirter Chris Moran Michele Callisaya Thanh Phan Loes C A Rutten-Jacobs Steve Bevan Christophe Tzourio Karen A Mather Perminder S Sachdev Cornelia M van Duijn Bradford B Worrall Martin Dichgans Steven J Kittner Hugh S Markus Mohammad A Ikram Myriam Fornage Lenore J Launer Sudha Seshadri W T Longstreth Stéphanie Debette

Neurology 2019 Jan 16. Epub 2019 Jan 16.

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http://dx.doi.org/10.1212/WNL.0000000000006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369905PMC
January 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Authors:
Tuomas O Kilpeläinen Amy R Bentley Raymond Noordam Yun Ju Sung Karen Schwander Thomas W Winkler Hermina Jakupović Daniel I Chasman Alisa Manning Ioanna Ntalla Hugues Aschard Michael R Brown Lisa de Las Fuentes Nora Franceschini Xiuqing Guo Dina Vojinovic Stella Aslibekyan Mary F Feitosa Minjung Kho Solomon K Musani Melissa Richard Heming Wang Zhe Wang Traci M Bartz Lawrence F Bielak Archie Campbell Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Changwei Li Kurt K Lohman Jonathan Marten Xueling Sim Albert V Smith Salman M Tajuddin Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Mariaelisa Graff Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Jing Hua Zhao Aldi T Kraja Brigitte Kühnel Federica Laguzzi Leo-Pekka Lyytikäinen Ilja M Nolte Rainer Rauramaa Muhammad Riaz Antonietta Robino Rico Rueedi Heather M Stringham Fumihiko Takeuchi Peter J van der Most Tibor V Varga Niek Verweij Erin B Ware Wanqing Wen Xiaoyin Li Lisa R Yanek Najaf Amin Donna K Arnett Eric Boerwinkle Marco Brumat Brian Cade Mickaël Canouil Yii-Der Ida Chen Maria Pina Concas John Connell Renée de Mutsert H Janaka de Silva Paul S de Vries Ayşe Demirkan Jingzhong Ding Charles B Eaton Jessica D Faul Yechiel Friedlander Kelley P Gabriel Mohsen Ghanbari Franco Giulianini Chi Charles Gu Dongfeng Gu Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Steven C Hunt M Arfan Ikram Jost B Jonas Woon-Puay Koh Pirjo Komulainen Jose E Krieger Stephen B Kritchevsky Zoltán Kutalik Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Karin Leander Rozenn N Lemaitre Cora E Lewis Jingjing Liang Jianjun Liu Reedik Mägi Ani Manichaikul Thomas Meitinger Andres Metspalu Yuri Milaneschi Karen L Mohlke Thomas H Mosley Alison D Murray Mike A Nalls Ei-Ei Khaing Nang Christopher P Nelson Sotoodehnia Nona Jill M Norris Chiamaka Vivian Nwuba Jeff O'Connell Nicholette D Palmer George J Papanicolau Raha Pazoki Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David J Porteous Alaitz Poveda Olli T Raitakari Stephen S Rich Neil Risch Jennifer G Robinson Lynda M Rose Igor Rudan Pamela J Schreiner Robert A Scott Stephen S Sidney Mario Sims Jennifer A Smith Harold Snieder Tamar Sofer John M Starr Barbara Sternfeld Konstantin Strauch Hua Tang Kent D Taylor Michael Y Tsai Jaakko Tuomilehto André G Uitterlinden M Yldau van der Ende Diana van Heemst Trudy Voortman Melanie Waldenberger Patrik Wennberg Gregory Wilson Yong-Bing Xiang Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Norihiro Kato Markku Laakso Timo A Lakka Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Nilesh J Samani Xiao-Ou Shu Pim van der Harst Jana V Van Vliet-Ostaptchouk Peter Vollenweider Lynne E Wagenknecht Ya X Wang Nicholas J Wareham David R Weir Tangchun Wu Wei Zheng Xiaofeng Zhu Michele K Evans Paul W Franks Vilmundur Gudnason Caroline Hayward Bernardo L Horta Tanika N Kelly Yongmei Liu Kari E North Alexandre C Pereira Paul M Ridker E Shyong Tai Rob M van Dam Ervin R Fox Sharon L R Kardia Ching-Ti Liu Dennis O Mook-Kanamori Michael A Province Susan Redline Cornelia M van Duijn Jerome I Rotter Charles B Kooperberg W James Gauderman Bruce M Psaty Kenneth Rice Patricia B Munroe Myriam Fornage L Adrienne Cupples Charles N Rotimi Alanna C Morrison Dabeeru C Rao Ruth J F Loos

Nat Commun 2019 01 22;10(1):376. Epub 2019 Jan 22.

Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, 10029, NY, USA.

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January 2019

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 12;50(12):1755

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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December 2018

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Authors:
Nora Franceschini Claudia Giambartolomei Paul S de Vries Chris Finan Joshua C Bis Rachael P Huntley Ruth C Lovering Salman M Tajuddin Thomas W Winkler Misa Graff Maryam Kavousi Caroline Dale Albert V Smith Edith Hofer Elisabeth M van Leeuwen Ilja M Nolte Lingyi Lu Markus Scholz Muralidharan Sargurupremraj Niina Pitkänen Oscar Franzén Peter K Joshi Raymond Noordam Riccardo E Marioni Shih-Jen Hwang Solomon K Musani Ulf Schminke Walter Palmas Aaron Isaacs Adolfo Correa Alan B Zonderman Albert Hofman Alexander Teumer Amanda J Cox André G Uitterlinden Andrew Wong Andries J Smit Anne B Newman Annie Britton Arno Ruusalepp Bengt Sennblad Bo Hedblad Bogdan Pasaniuc Brenda W Penninx Carl D Langefeld Christina L Wassel Christophe Tzourio Cristiano Fava Damiano Baldassarre Daniel H O'Leary Daniel Teupser Diana Kuh Elena Tremoli Elmo Mannarino Enzo Grossi Eric Boerwinkle Eric E Schadt Erik Ingelsson Fabrizio Veglia Fernando Rivadeneira Frank Beutner Ganesh Chauhan Gerardo Heiss Harold Snieder Harry Campbell Henry Völzke Hugh S Markus Ian J Deary J Wouter Jukema Jacqueline de Graaf Jacqueline Price Janne Pott Jemma C Hopewell Jingjing Liang Joachim Thiery Jorgen Engmann Karl Gertow Kenneth Rice Kent D Taylor Klodian Dhana Lambertus A L M Kiemeney Lars Lind Laura M Raffield Lenore J Launer Lesca M Holdt Marcus Dörr Martin Dichgans Matthew Traylor Matthias Sitzer Meena Kumari Mika Kivimaki Mike A Nalls Olle Melander Olli Raitakari Oscar H Franco Oscar L Rueda-Ochoa Panos Roussos Peter H Whincup Philippe Amouyel Philippe Giral Pramod Anugu Quenna Wong Rainer Malik Rainer Rauramaa Ralph Burkhardt Rebecca Hardy Reinhold Schmidt Renée de Mutsert Richard W Morris Rona J Strawbridge S Goya Wannamethee Sara Hägg Sonia Shah Stela McLachlan Stella Trompet Sudha Seshadri Sudhir Kurl Susan R Heckbert Susan Ring Tamara B Harris Terho Lehtimäki Tessel E Galesloot Tina Shah Ulf de Faire Vincent Plagnol Wayne D Rosamond Wendy Post Xiaofeng Zhu Xiaoling Zhang Xiuqing Guo Yasaman Saba Abbas Dehghan Adrie Seldenrijk Alanna C Morrison Anders Hamsten Bruce M Psaty Cornelia M van Duijn Deborah A Lawlor Dennis O Mook-Kanamori Donald W Bowden Helena Schmidt James F Wilson James G Wilson Jerome I Rotter Joanna M Wardlaw John Deanfield Julian Halcox Leo-Pekka Lyytikäinen Markus Loeffler Michele K Evans Stéphanie Debette Steve E Humphries Uwe Völker Vilmundur Gudnason Aroon D Hingorani Johan L M Björkegren Juan P Casas Christopher J O'Donnell

Nat Commun 2018 12 3;9(1):5141. Epub 2018 Dec 3.

Intramural Administration Management Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-07340-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277418PMC
December 2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 10 17;50(10):1412-1425. Epub 2018 Sep 17.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284793PMC
October 2018

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.

Nat Commun 2018 09 26;9(1):3945. Epub 2018 Sep 26.

The University of Texas Health Science Center at Houston Institute of Molecular Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/s41467-018-06234-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158214PMC
September 2018

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.

Stroke 2018 08;49(8):1812-1819

From the Institute of Molecular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston (M.F., X.J.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202149PMC
August 2018

Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: A systematic review and meta-analysis.

Neurosci Biobehav Rev 2018 07 13;90:164-173. Epub 2018 Apr 13.

CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre+, PO Box 616, 6200 MD, Maastricht, The Netherlands; Department of Internal Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123527PMC
July 2018

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.

Authors:
Bram P Prins Timothy J Mead Jennifer A Brody Gardar Sveinbjornsson Ioanna Ntalla Nathan A Bihlmeyer Marten van den Berg Jette Bork-Jensen Stefania Cappellani Stefan Van Duijvenboden Nikolai T Klena George C Gabriel Xiaoqin Liu Cagri Gulec Niels Grarup Jeffrey Haessler Leanne M Hall Annamaria Iorio Aaron Isaacs Ruifang Li-Gao Honghuang Lin Ching-Ti Liu Leo-Pekka Lyytikäinen Jonathan Marten Hao Mei Martina Müller-Nurasyid Michele Orini Sandosh Padmanabhan Farid Radmanesh Julia Ramirez Antonietta Robino Molly Schwartz Jessica van Setten Albert V Smith Niek Verweij Helen R Warren Stefan Weiss Alvaro Alonso David O Arnar Michiel L Bots Rudolf A de Boer Anna F Dominiczak Mark Eijgelsheim Patrick T Ellinor Xiuqing Guo Stephan B Felix Tamara B Harris Caroline Hayward Susan R Heckbert Paul L Huang J W Jukema Mika Kähönen Jan A Kors Pier D Lambiase Lenore J Launer Man Li Allan Linneberg Christopher P Nelson Oluf Pedersen Marco Perez Annette Peters Ozren Polasek Bruce M Psaty Olli T Raitakari Kenneth M Rice Jerome I Rotter Moritz F Sinner Elsayed Z Soliman Tim D Spector Konstantin Strauch Unnur Thorsteinsdottir Andrew Tinker Stella Trompet André Uitterlinden Ilonca Vaartjes Peter van der Meer Uwe Völker Henry Völzke Melanie Waldenberger James G Wilson Zhijun Xie Folkert W Asselbergs Marcus Dörr Cornelia M van Duijn Paolo Gasparini Daniel F Gudbjartsson Vilmundur Gudnason Torben Hansen Stefan Kääb Jørgen K Kanters Charles Kooperberg Terho Lehtimäki Henry J Lin Steven A Lubitz Dennis O Mook-Kanamori Francesco J Conti Christopher H Newton-Cheh Jonathan Rosand Igor Rudan Nilesh J Samani Gianfranco Sinagra Blair H Smith Hilma Holm Bruno H Stricker Sheila Ulivi Nona Sotoodehnia Suneel S Apte Pim van der Harst Kari Stefansson Patricia B Munroe Dan E Arking Cecilia W Lo Yalda Jamshidi

Genome Biol 2018 07 17;19(1):87. Epub 2018 Jul 17.

Genetics Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London, SW17 0RE, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048820PMC
July 2018

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

Authors:
Jessica van Setten Jennifer A Brody Yalda Jamshidi Brenton R Swenson Anne M Butler Harry Campbell Fabiola M Del Greco Daniel S Evans Quince Gibson Daniel F Gudbjartsson Kathleen F Kerr Bouwe P Krijthe Leo-Pekka Lyytikäinen Christian Müller Martina Müller-Nurasyid Ilja M Nolte Sandosh Padmanabhan Marylyn D Ritchie Antonietta Robino Albert V Smith Maristella Steri Toshiko Tanaka Alexander Teumer Stella Trompet Sheila Ulivi Niek Verweij Xiaoyan Yin David O Arnar Folkert W Asselbergs Joel S Bader John Barnard Josh Bis Stefan Blankenberg Eric Boerwinkle Yuki Bradford Brendan M Buckley Mina K Chung Dana Crawford Marcel den Hoed Josh C Denny Anna F Dominiczak Georg B Ehret Mark Eijgelsheim Patrick T Ellinor Stephan B Felix Oscar H Franco Lude Franke Tamara B Harris Hilma Holm Gandin Ilaria Annamaria Iorio Mika Kähönen Ivana Kolcic Jan A Kors Edward G Lakatta Lenore J Launer Honghuang Lin Henry J Lin Ruth J F Loos Steven A Lubitz Peter W Macfarlane Jared W Magnani Irene Mateo Leach Thomas Meitinger Braxton D Mitchell Thomas Munzel George J Papanicolaou Annette Peters Arne Pfeufer Peter P Pramstaller Olli T Raitakari Jerome I Rotter Igor Rudan Nilesh J Samani David Schlessinger Claudia T Silva Aldana Moritz F Sinner Jonathan D Smith Harold Snieder Elsayed Z Soliman Timothy D Spector David J Stott Konstantin Strauch Kirill V Tarasov Unnur Thorsteinsdottir Andre G Uitterlinden David R Van Wagoner Uwe Völker Henry Völzke Melanie Waldenberger Harm Jan Westra Philipp S Wild Tanja Zeller Alvaro Alonso Christy L Avery Stefania Bandinelli Emelia J Benjamin Francesco Cucca Marcus Dörr Luigi Ferrucci Paolo Gasparini Vilmundur Gudnason Caroline Hayward Susan R Heckbert Andrew A Hicks J Wouter Jukema Stefan Kääb Terho Lehtimäki Yongmei Liu Patricia B Munroe Afshin Parsa Ozren Polasek Bruce M Psaty Dan M Roden Renate B Schnabel Gianfranco Sinagra Kari Stefansson Bruno H Stricker Pim van der Harst Cornelia M van Duijn James F Wilson Sina A Gharib Paul I W de Bakker Aaron Isaacs Dan E Arking Nona Sotoodehnia

Nat Commun 2018 07 25;9(1):2904. Epub 2018 Jul 25.

Departments of Medicine and Epidemiology, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060178PMC
July 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.

Authors:
Honghuang Lin Jessica van Setten Albert V Smith Nathan A Bihlmeyer Helen R Warren Jennifer A Brody Farid Radmanesh Leanne Hall Niels Grarup Martina Müller-Nurasyid Thibaud Boutin Niek Verweij Henry J Lin Ruifang Li-Gao Marten E van den Berg Jonathan Marten Stefan Weiss Bram P Prins Jeffrey Haessler Leo-Pekka Lyytikäinen Hao Mei Tamara B Harris Lenore J Launer Man Li Alvaro Alonso Elsayed Z Soliman John M Connell Paul L Huang Lu-Chen Weng Heather S Jameson William Hucker Alan Hanley Nathan R Tucker Yii-Der Ida Chen Joshua C Bis Kenneth M Rice Colleen M Sitlani Jan A Kors Zhijun Xie Chengping Wen Jared W Magnani Christopher P Nelson Jørgen K Kanters Moritz F Sinner Konstantin Strauch Annette Peters Melanie Waldenberger Thomas Meitinger Jette Bork-Jensen Oluf Pedersen Allan Linneberg Igor Rudan Rudolf A de Boer Peter van der Meer Jie Yao Xiuqing Guo Kent D Taylor Nona Sotoodehnia Jerome I Rotter Dennis O Mook-Kanamori Stella Trompet Fernando Rivadeneira André Uitterlinden Mark Eijgelsheim Sandosh Padmanabhan Blair H Smith Henry Völzke Stephan B Felix Georg Homuth Uwe Völker Massimo Mangino Timothy D Spector Michiel L Bots Marco Perez Mika Kähönen Olli T Raitakari Vilmundur Gudnason Dan E Arking Patricia B Munroe Bruce M Psaty Cornelia M van Duijn Emelia J Benjamin Jonathan Rosand Nilesh J Samani Torben Hansen Stefan Kääb Ozren Polasek Pim van der Harst Susan R Heckbert J Wouter Jukema Bruno H Stricker Caroline Hayward Marcus Dörr Yalda Jamshidi Folkert W Asselbergs Charles Kooperberg Terho Lehtimäki James G Wilson Patrick T Ellinor Steven A Lubitz Aaron Isaacs

Circ Genom Precis Med 2018 05;11(5):e002037

Section of Computational Biomedicine (H.L.) and Section of Cardiovascular Medicine (E.J.B.), Department of Medicine, Boston University School of Medicine, MA. National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, MA (H.L., E.J.B.). Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, The Netherlands (J.v.S., F.W.A.). Icelandic Heart Association, Kopavogur (A.V.S., V.G.). Faculty of Medicine, University of Iceland, Reykjavik (A.V.S., V.G.). Predoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine (N.A.B.) and McKusick-Nathans Institute of Genetic Medicine (D.E.A.), Johns Hopkins University School of Medicine, Baltimore, MD. William Harvey Research Institute (H.R.W., P.B.M.) and NIHR Barts Cardiovascular Research Unit (H.R.W., P.B.M.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom. Cardiovascular Health Research Unit, Department of Medicine (J.A.B., J.C.B., C.M.S.), Department of Biostatistics (K.M.R.), Cardiovascular Health Research Unit, Division of Cardiology, Departments of Medicine and Epidemiology (N.S.), Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services (B.M.P.), and Cardiovascular Health Research Unit, Department of Epidemiology (S.R.H.), University of Washington, Seattle. Center for Human Genetic Research (F. Radmanesh, J.R.) and Cardiovascular Research Center (P.L.H., L.-C.W., H.S.J., W.H., A.H., N.R.T., P.T.E., S.A.L.), Massachusetts General Hospital, Boston. Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA (L.-C.W., P.T.E., S.A.L.). Department of Cardiovascular Sciences, University of Leicester, United Kingdom (L.H., C.P.N., N.J.S.). NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, United Kingdom (L.H., C.P.N., N.J.S.). The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences (N.G., J.B.-J., O. Pedersen, T.H.), Laboratory of Experimental Cardiology (J.K.K.), and Department of Clinical Medicine, Faculty of Health and Medical Sciences (A.L.), University of Copenhagen, Denmark. Department of Medicine I, University Hospital Munich, Ludwig Maximilian's University Munich, Germany (M.M.-N., M.F.S., S.K.). Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Germany (K.S.). DZHK (German Cardiovascular Research Centre), Partner Site: Munich Heart Alliance, Germany (M.M.-N., M.F.S., A.P., T.M., S.K.). Institute of Genetic Epidemiology (M.M.-N., K.S.), Institute of Epidemiology II (A.P., M.W.), Research Unit of Molecular Epidemiology (M.W.), and Institute of Human Genetics (T.M.), Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (T.B., J.M., C.H.) and Usher Institute of Population Health Sciences and Informatics (I.R.), University of Edinburgh, United Kingdom. University of Groningen, University Medical Center Groningen, Department of Cardiology, The Netherlands (N.V., R.A.d.B., P.v.d.M., P.v.d.H.). Institute for Translational Genomics and Population Sciences and Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (H.J.L., Y.-D.I.C., J.Y., X.G., K.D.T., J.I.R.). Department of Clinical Epidemiology (R.L.-G., D.O.M.-K.) and Department of Cardiology (S.T., J.W.J.), Leiden University Medical Center, The Netherlands. Department of Medical Informatics (M.E.v.d.B.), Human Genomics Facility (F. Rivadeneira), Human Genotyping Facility (A.U.), and Department of Epidemiology (M.E., B.H. Stricker), Erasmus MC, University Medical Center Rotterdam, The Netherlands. Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt-University Greifswald, Germany (S.W., G.H., U.V.). DZHK (German Cardiovascular Research Centre), Partner Site Greifswald, Germany (S.W., H.V., S.B.F., U.V., M.D.). Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA (J.H., C.K.). Department of Clinical Chemistry, Fimlab Laboratories and Faculty of Medicine and Life Sciences (L.-P.L., T.L.) and Department of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Life Sciences (M.K.), University of Tampere, Finland. Department of Data Science (H.M.) and Physiology and Biophysics (J.G.W.), University of Mississippi Medical Center, Jackson. Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD (T.B.H., L.J.L.). Division of Nephrology and Hypertension, Internal Medicine, School of Medicine, University of Utah, Salt Lake City (M.L.). Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.). Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston Salem, NC (E.Z.S.). Medical Research Institute (J.M.C.) and Division of Population Health Sciences (B.H. Smith), Ninewells Hospital and Medical School, University of Dundee, United Kingdom. Department of Medical Informatics (J.A.K.) and Genetic Epidemiology Unit, Department of Epidemiology (C.M.v.D.), Erasmus MC, Rotterdam, The Netherlands. TCM Clinical Basis Institute, Zhejiang Chinese Medicine University, Hangzhou, China (Z.X., C.W.). Division of Cardiology, Department of Medicine, UPMC Heart and Vascular Institute, University of Pittsburgh, PA (J.W.M.). German Center for Diabetes Research, Neuherberg, Germany (A.P.). Institute of Human Genetics, Technische Universität München, Germany (T.M.). Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen (A.L.). Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.). British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Scotland (S.P.). Institute for Community Medicine (H.V.) and Department of Internal Medicine B (S.B.F., M.D.), University Medicine Greifswald, Germany. Department of Twin Research and Genetic Epidemiology, King's College London, United Kingdom (M.M., T.D.S.). Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands (M.L.B.). Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA (M.P.). Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (O.T.R.). Kaiser Permanente Washington Health Research Institute, Kaiser Foundation Health Plan of Washington, Seattle (B.M.P., S.R.H.). Faculty of Medicine, University of Split, Croatia (O. Polasek). Cardiogenetics Lab, Genetics and Molecular Cell Sciences Research Centre, Cardiovascular and Cell Sciences Institute, St George's, University of London, Cranmer Terrace, United Kingdom (B.P.P., Y.J.). Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands (F.W.A.). Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom (F.W.A.). Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, United Kingdom; CARIM School for Cardiovascular Diseases, Maastricht Centre for Systems Biology (MaCSBio) and Department of Biochemistry, Maastricht University, The Netherlands (A.I.).

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http://dx.doi.org/10.1161/CIRCGEN.117.002037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951629PMC
May 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-018-0058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Authors:
Anubha Mahajan Jennifer Wessel Sara M Willems Wei Zhao Neil R Robertson Audrey Y Chu Wei Gan Hidetoshi Kitajima Daniel Taliun N William Rayner Xiuqing Guo Yingchang Lu Man Li Richard A Jensen Yao Hu Shaofeng Huo Kurt K Lohman Weihua Zhang James P Cook Bram Peter Prins Jason Flannick Niels Grarup Vassily Vladimirovich Trubetskoy Jasmina Kravic Young Jin Kim Denis V Rybin Hanieh Yaghootkar Martina Müller-Nurasyid Karina Meidtner Ruifang Li-Gao Tibor V Varga Jonathan Marten Jin Li Albert Vernon Smith Ping An Symen Ligthart Stefan Gustafsson Giovanni Malerba Ayse Demirkan Juan Fernandez Tajes Valgerdur Steinthorsdottir Matthias Wuttke Cécile Lecoeur Michael Preuss Lawrence F Bielak Marielisa Graff Heather M Highland Anne E Justice Dajiang J Liu Eirini Marouli Gina Marie Peloso Helen R Warren Saima Afaq Shoaib Afzal Emma Ahlqvist Peter Almgren Najaf Amin Lia B Bang Alain G Bertoni Cristina Bombieri Jette Bork-Jensen Ivan Brandslund Jennifer A Brody Noël P Burtt Mickaël Canouil Yii-Der Ida Chen Yoon Shin Cho Cramer Christensen Sophie V Eastwood Kai-Uwe Eckardt Krista Fischer Giovanni Gambaro Vilmantas Giedraitis Megan L Grove Hugoline G de Haan Sophie Hackinger Yang Hai Sohee Han Anne Tybjærg-Hansen Marie-France Hivert Bo Isomaa Susanne Jäger Marit E Jørgensen Torben Jørgensen Annemari Käräjämäki Bong-Jo Kim Sung Soo Kim Heikki A Koistinen Peter Kovacs Jennifer Kriebel Florian Kronenberg Kristi Läll Leslie A Lange Jung-Jin Lee Benjamin Lehne Huaixing Li Keng-Hung Lin Allan Linneberg Ching-Ti Liu Jun Liu Marie Loh Reedik Mägi Vasiliki Mamakou Roberta McKean-Cowdin Girish Nadkarni Matt Neville Sune F Nielsen Ioanna Ntalla Patricia A Peyser Wolfgang Rathmann Kenneth Rice Stephen S Rich Line Rode Olov Rolandsson Sebastian Schönherr Elizabeth Selvin Kerrin S Small Alena Stančáková Praveen Surendran Kent D Taylor Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Adrienne Tin Anke Tönjes Anette Varbo Daniel R Witte Andrew R Wood Pranav Yajnik Jie Yao Loïc Yengo Robin Young Philippe Amouyel Heiner Boeing Eric Boerwinkle Erwin P Bottinger Rajiv Chowdhury Francis S Collins George Dedoussis Abbas Dehghan Panos Deloukas Marco M Ferrario Jean Ferrières Jose C Florez Philippe Frossard Vilmundur Gudnason Tamara B Harris Susan R Heckbert Joanna M M Howson Martin Ingelsson Sekar Kathiresan Frank Kee Johanna Kuusisto Claudia Langenberg Lenore J Launer Cecilia M Lindgren Satu Männistö Thomas Meitinger Olle Melander Karen L Mohlke Marie Moitry Andrew D Morris Alison D Murray Renée de Mutsert Marju Orho-Melander Katharine R Owen Markus Perola Annette Peters Michael A Province Asif Rasheed Paul M Ridker Fernando Rivadineira Frits R Rosendaal Anders H Rosengren Veikko Salomaa Wayne H-H Sheu Rob Sladek Blair H Smith Konstantin Strauch André G Uitterlinden Rohit Varma Cristen J Willer Matthias Blüher Adam S Butterworth John Campbell Chambers Daniel I Chasman John Danesh Cornelia van Duijn Josée Dupuis Oscar H Franco Paul W Franks Philippe Froguel Harald Grallert Leif Groop Bok-Ghee Han Torben Hansen Andrew T Hattersley Caroline Hayward Erik Ingelsson Sharon L R Kardia Fredrik Karpe Jaspal Singh Kooner Anna Köttgen Kari Kuulasmaa Markku Laakso Xu Lin Lars Lind Yongmei Liu Ruth J F Loos Jonathan Marchini Andres Metspalu Dennis Mook-Kanamori Børge G Nordestgaard Colin N A Palmer James S Pankow Oluf Pedersen Bruce M Psaty Rainer Rauramaa Naveed Sattar Matthias B Schulze Nicole Soranzo Timothy D Spector Kari Stefansson Michael Stumvoll Unnur Thorsteinsdottir Tiinamaija Tuomi Jaakko Tuomilehto Nicholas J Wareham James G Wilson Eleftheria Zeggini Robert A Scott Inês Barroso Timothy M Frayling Mark O Goodarzi James B Meigs Michael Boehnke Danish Saleheen Andrew P Morris Jerome I Rotter Mark I McCarthy

Nat Genet 2018 04 9;50(4):559-571. Epub 2018 Apr 9.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41588-018-0084-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898373PMC
April 2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Authors:
Yun J Sung Thomas W Winkler Lisa de Las Fuentes Amy R Bentley Michael R Brown Aldi T Kraja Karen Schwander Ioanna Ntalla Xiuqing Guo Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Mary F Feitosa Tuomas O Kilpeläinen Melissa A Richard Raymond Noordam Stella Aslibekyan Hugues Aschard Traci M Bartz Rajkumar Dorajoo Yongmei Liu Alisa K Manning Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Helen R Warren Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando Pires Hartwig Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian 'an Luan Colin A McKenzie He Meian Christopher P Nelson Rainer Rauramaa Nicole Schupf Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Claudia P Cabrera Brian Cade Yu Caizheng Archie Campbell Mickaël Canouil Aravinda Chakravarti Ganesh Chauhan Kaare Christensen Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Stephanie Debette Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Virginia A Fisher Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante Misa Graff C Charles Gu Dongfeng Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Albert Hofman Barbara V Howard Steven Hunt Marguerite R Irvin Yucheng Jia Roby Joehanes Anne E Justice Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Pirjo Komulainen Charles Kooperberg Jose E Krieger Michiaki Kubo Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Sing Hui Lim Shiow Lin Ching-Ti Liu Jianjun Liu Jingmin Liu Kiang Liu Yeheng Liu Marie Loh Kurt K Lohman Jirong Long Tin Louie Reedik Mägi Anubha Mahajan Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Andrew P Morris Thomas H Mosley Peter Munson Alison D Murray Mike A Nalls Ubaydah Nasri Jill M Norris Kari North Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Sudha Seshadri Peter Sever Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya X Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost B Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Anne B Newman Albertine J Oldehinkel Alexandre C Pereira Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason Sharon L R Kardia Stephen B Kritchevsky Daniel Levy Jeff R O'Connell Bruce M Psaty Rob M van Dam Mario Sims Donna K Arnett Dennis O Mook-Kanamori Tanika N Kelly Ervin R Fox Caroline Hayward Myriam Fornage Charles N Rotimi Michael A Province Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Mark J Caulfield Paul Elliott Kenneth Rice Patricia B Munroe Alanna C Morrison L Adrienne Cupples Dabeeru C Rao Daniel I Chasman

Am J Hum Genet 2018 03 15;102(3):375-400. Epub 2018 Feb 15.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985266PMC
March 2018

Differential associations between retinal signs and CMBs by location: The AGES-Reykjavik Study.

Neurology 2018 01 13;90(2):e142-e148. Epub 2017 Dec 13.

From the Intramural Research Program (C.Q., J.D., Q.Z., L.J.L.), Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD; Aging Research Center (C.Q.), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University, Sweden; Icelandic Heart Association (S.S., G.E., V.G.), Kopavogur; Division of Epidemiology and Clinical Research (D.E.F., M.F.C.), National Eye Institute, NIH, Bethesda, MD; Ophthalmology and Visual Sciences (R.K.), University of Wisconsin Madison; Department of Radiology (M.A.v.B.), Leiden University Medical Centre, the Netherlands; and Faculty of Medicine (V.G.), University of Iceland, Reykjavik.

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http://dx.doi.org/10.1212/WNL.0000000000004792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772152PMC
January 2018

Vascular and dopaminergic contributors to mild parkinsonian signs in older adults.

Neurology 2018 01 15;90(3):e223-e229. Epub 2017 Dec 15.

From the Department of Epidemiology, Graduate School of Public Health (A.L.R., C.R.), and Department of Psychiatry (H.J.A.), University of Pittsburgh, PA; Departments of Radiology and Neurology (N.I.B.), University of Michigan, Ann Arbor; Laboratory of Epidemiology and Population Sciences (L.J.L.), National Institute on Aging, Baltimore, MD; and Departments of Psychiatry, Neurology, and Epidemiology & Biostatistics (K.Y.), University of California, San Francisco.

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http://dx.doi.org/10.1212/WNL.0000000000004842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772161PMC
January 2018

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals.

Authors:
Nathan A Bihlmeyer Jennifer A Brody Albert Vernon Smith Helen R Warren Honghuang Lin Aaron Isaacs Ching-Ti Liu Jonathan Marten Farid Radmanesh Leanne M Hall Niels Grarup Hao Mei Martina Müller-Nurasyid Jennifer E Huffman Niek Verweij Xiuqing Guo Jie Yao Ruifang Li-Gao Marten van den Berg Stefan Weiss Bram P Prins Jessica van Setten Jeffrey Haessler Leo-Pekka Lyytikäinen Man Li Alvaro Alonso Elsayed Z Soliman Joshua C Bis Tom Austin Yii-Der Ida Chen Bruce M Psaty Tamara B Harrris Lenore J Launer Sandosh Padmanabhan Anna Dominiczak Paul L Huang Zhijun Xie Patrick T Ellinor Jan A Kors Archie Campbell Alison D Murray Christopher P Nelson Martin D Tobin Jette Bork-Jensen Torben Hansen Oluf Pedersen Allan Linneberg Moritz F Sinner Annette Peters Melanie Waldenberger Thomas Meitinger Siegfried Perz Ivana Kolcic Igor Rudan Rudolf A de Boer Peter van der Meer Henry J Lin Kent D Taylor Renée de Mutsert Stella Trompet J Wouter Jukema Arie C Maan Bruno H C Stricker Fernando Rivadeneira André Uitterlinden Uwe Völker Georg Homuth Henry Völzke Stephan B Felix Massimo Mangino Timothy D Spector Michiel L Bots Marco Perez Olli T Raitakari Mika Kähönen Nina Mononen Vilmundur Gudnason Patricia B Munroe Steven A Lubitz Cornelia M van Duijn Christopher H Newton-Cheh Caroline Hayward Jonathan Rosand Nilesh J Samani Jørgen K Kanters James G Wilson Stefan Kääb Ozren Polasek Pim van der Harst Susan R Heckbert Jerome I Rotter Dennis O Mook-Kanamori Mark Eijgelsheim Marcus Dörr Yalda Jamshidi Folkert W Asselbergs Charles Kooperberg Terho Lehtimäki Dan E Arking Nona Sotoodehnia

Circ Genom Precis Med 2018 01;11(1):e001758

From the Predoctoral Training Program in Human Genetics (N.A.B.) and McKusick-Nathans Institute of Genetic Medicine (N.A.B., D.E.A.), Johns Hopkins School of Medicine, Baltimore, MD; Cardiovascular Health Research Unit, Department of Medicine (J.A.B., J.C.B., T.A., N.S.), Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services (B.M.P.), and Cardiovascular Health Research Unit, Department of Epidemiology (S.R.H.), University of Washington, Seattle; Icelandic Heart Association, Kopavogur (A.V.S., V.G.); Faculty of Medicine, University of Iceland, Reykavik (A.V.S., V.G.); Clinical Pharmacology Department, William Harvey Research Institute, Barts and London School of Medicine and Dentistry (H.R.W., P.B.M.) and NIHR Barts Cardiovascular Biomedical Research Unit (H.R.W., P.B.M.), Queen Mary University of London, United Kingdom; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, MA (H.L., Z.X.); School for Cardiovascular Diseases, Maastricht Center for Systems Biology and Department of Biochemistry, Maastricht University, The Netherlands (A.I.); Genetic Epidemiology Unit, Department of Epidemiology (A.I., C.M.v.D.) and Department of Medical Informatics (J.A.K.), Erasmus University Medical Center, Rotterdam, The Netherlands; Biostatistics Department, Boston University School of Public Health, MA (C.-T.L.); Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.M., C.H.), Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine (A.C.), and Usher Institute for Population Health Sciences and Informatics (I.R.), University of Edinburgh, United Kingdom; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (F.R., P.T.E., S.A.L., J.R.); Center for Human Genetic Research (F.R., J.R.), Cardiovascular Research Center (P.L.H., P.T.E., S.A.L.), and Center for Human Genetic Research and Cardiovascular Research Center (C.H.N.-C.), Harvard Medical School, Massachusetts General Hospital, Boston; Department of Cardiovascular Sciences (L.M.H., C.P.N., N.J.S.) and Genetic Epidemiology Group, Department of Health Sciences (M.D.T.), University of Leicester, United Kingdom; NIHR Leicester Cardiovascular Biomedical Research Unit (L.M.H., C.P.N.) and NIHR Leicester Respiratory Biomedical Research Unit (M.D.T.), Glenfield Hospital, United Kingdom; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences (N.G., J.B.-J., T.H., O.P.), Department of Clinical Medicine, Faculty of Health and Medical Sciences (A.L.), and Laboratory of Experimental Cardiology (J.K.K.), University of Copenhagen, Denmark; Department of Data Science, School of Population Health (H.M.) and Physiology and Biophysics (J.G.W.), University of Mississippi Medical Center, Jackson; Institute of Genetic Epidemiology (M.M.-N.), Institute of Epidemiology II (A.P., M.W., S.P.), Research Unit of Molecular Epidemiology (M.W.), and Institute of Human Genetics (T.M.), Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg; Department of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Germany (M.M.-N., M.F.S., S.K.); DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance (M.M.-N., M.F.S., A.P., T.M., S.K.); MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Scotland (J.E.H.); Department of Cardiology (N.V., R.A.d.B., P.v.d.M., P.v.d.H.) and Department of Internal Medicine (M.E.), University Medical Center Groningen, University of Groningen, The Netherlands; Institute for Translational Genomics and Population Sciences and Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance (X.G., J.Y., Y.-D.I.C.); Department of Clinical Epidemiology (R.L.-G., R.d.M.) and University of Split School of Medicine (I.K., O.P.), University of Split, Croatia; Departments of Cardiology (S.T., J.W.J., A.C.M.), Gerontology and Geriatrics (S.T.), and Public Health and Primary Care (D.O.M.-K.), Leiden University Medical Center, The Netherlands; Departments of Medical Informatics (M.v.d.B.), Epidemiology (B.H.C.S.), and Epidemiology (M.E.), Erasmus MC - University Medical Center Rotterdam, The Netherlands; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt-University, Greifswald, Germany (S.W., U.V., G.H.); DZHK (German Centre for Cardiovascular Research), partner site Greifswald (S.W., U.V., H.V., S.B.F., M.D.); Cardiogenetics Lab, Genetics and Molecular Cell Sciences Research Centre, Cardiovascular and Cell Sciences Institute, St George's, University of London, United Kingdom (B.P.P., Y.J.); Division Heart and Lungs, Department of Cardiology, (J.v.S., F.W.A.) and Julius Center for Health Sciences and Primary Care (M.L.B.), University Medical Center Utrecht, The Netherlands; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA (J.H., C.K.); Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., N.M., T.L.); Department of Clinical Physiology, Tampere University Hospital, University of Tampere School of Medicine, Finland (M.K.); Division of Nephrology and Hypertension, Internal Medicine, School of Medicine, University of Utah, Salt Lake City (M.L.); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.); Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, NC (E.Z.S.); Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD (T.B.H., L.J.L.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom (S.P., A.D.); Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, United Kingdom (A.D.M.); Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen (A.L.); Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark (A.L.); German Center for Diabetes Research, Neuherberg (A.P.); Institute of Human Genetics, Technische Universität München, Germany (T.M.); Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands (J.W.J.); Interuniversity Cardiology Institute of Netherlands, Utrecht (J.W.J.); Inspectorate of Health Care, Utrecht, The Netherlands (B.H.C.S.); Human Genomics Facility (F.R.) and Human Genotyping Facility (A.U.), Erasmus MC - University Medical Center Rotterdam, The Netherlands; Institute for Community Medicine (H.V.) and Department of Internal Medicine B (S.B.F., M.D.), University Medicine Greifswald, Germany; Department of Twin Research and Genetic Epidemiology, King's College London, United Kingdom (M.M., T.D.S.); Stanford School of Medicine, CA (M.P.); Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (O.T.R.); Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge (C.H.N.-C.); NIHR Leicester Biomedical Research Unit in Cardiovascular Disease, United Kingdom (N.J.S.); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht (F.W.A.); and Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, United Kingdom (F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.117.001758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992491PMC
January 2018

Visit-to-Visit Blood Pressure Variability in Young Adulthood and Hippocampal Volume and Integrity at Middle Age: The CARDIA Study (Coronary Artery Risk Development in Young Adults).

Hypertension 2017 12 9;70(6):1091-1098. Epub 2017 Oct 9.

From the Department of Preventive Medicine, University of Mississippi Medical Center, Jackson (Y.Y.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Y., Y.G.T., N.B.A., M.P.B., K.L., P.G., D.M.L.-J.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD (J.P.R.); Division of General Medicine, University of Michigan, Ann Arbor (D.A.L.); Department of Radiology, University of Pennsylvania Health System, Philadelphia (R.N.B.); Department of Family Medicine, Hypertension Research Program, University of North Carolina at Chapel Hill (A.J.V.); Department of Medicine, Columbia University Medical Center, New York, NY (D.S.); Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (P.J.S.); Division of Research, Kaiser Permanente of Northern California, Oakland (S.S.); Department of Epidemiology and Biostatistics, University of California, San Francisco (M.J.P.); and Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD (L.J.L.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680098PMC
December 2017

Fibrosis as measured by the biomarker, tissue inhibitor metalloproteinase-1, predicts mortality in Age Gene Environment Susceptibility-Reykjavik (AGES-Reykjavik) Study.

Eur Heart J 2017 Dec;38(46):3423-3430

Department of Health and Human Services, National Heart, Lung, and Blood, National Institutes of Health, Building 10, Room B1D416, MSC 1061, 10 Center Drive, Bethesda, MD 20892-1061, USA.

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http://dx.doi.org/10.1093/eurheartj/ehx510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837193PMC
December 2017

Exome-wide association study of plasma lipids in >300,000 individuals.

Authors:
Dajiang J Liu Gina M Peloso Haojie Yu Adam S Butterworth Xiao Wang Anubha Mahajan Danish Saleheen Connor Emdin Dewan Alam Alexessander Couto Alves Philippe Amouyel Emanuele Di Angelantonio Dominique Arveiler Themistocles L Assimes Paul L Auer Usman Baber Christie M Ballantyne Lia E Bang Marianne Benn Joshua C Bis Michael Boehnke Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Ivan Brandslund Morris Brown Fabio Busonero Mark J Caulfield John C Chambers Daniel I Chasman Y Eugene Chen Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu John M Connell Francesco Cucca L Adrienne Cupples Scott M Damrauer Gail Davies Ian J Deary George Dedoussis Joshua C Denny Anna Dominiczak Marie-Pierre Dubé Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Aliki-Eleni Farmaki Mary F Feitosa Marco Ferrario Jean Ferrieres Ian Ford Myriam Fornage Paul W Franks Timothy M Frayling Ruth Frikke-Schmidt Lars G Fritsche Philippe Frossard Valentin Fuster Santhi K Ganesh Wei Gao Melissa E Garcia Christian Gieger Franco Giulianini Mark O Goodarzi Harald Grallert Niels Grarup Leif Groop Megan L Grove Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Joel N Hirschhorn Oddgeir L Holmen Jennifer Huffman Yong Huo Kristian Hveem Sehrish Jabeen Anne U Jackson Johanna Jakobsdottir Marjo-Riitta Jarvelin Gorm B Jensen Marit E Jørgensen J Wouter Jukema Johanne M Justesen Pia R Kamstrup Stavroula Kanoni Fredrik Karpe Frank Kee Amit V Khera Derek Klarin Heikki A Koistinen Jaspal S Kooner Charles Kooperberg Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo Lakka Claudia Langenberg Anne Langsted Lenore J Launer Torsten Lauritzen David C M Liewald Li An Lin Allan Linneberg Ruth J F Loos Yingchang Lu Xiangfeng Lu Reedik Mägi Anders Malarstig Ani Manichaikul Alisa K Manning Pekka Mäntyselkä Eirini Marouli Nicholas G D Masca Andrea Maschio James B Meigs Olle Melander Andres Metspalu Andrew P Morris Alanna C Morrison Antonella Mulas Martina Müller-Nurasyid Patricia B Munroe Matt J Neville Jonas B Nielsen Sune F Nielsen Børge G Nordestgaard Jose M Ordovas Roxana Mehran Christoper J O'Donnell Marju Orho-Melander Cliona M Molony Pieter Muntendam Sandosh Padmanabhan Colin N A Palmer Dorota Pasko Aniruddh P Patel Oluf Pedersen Markus Perola Annette Peters Charlotta Pisinger Giorgio Pistis Ozren Polasek Neil Poulter Bruce M Psaty Daniel J Rader Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Stephen S Rich Paul M Ridker John D Rioux Neil R Robertson Dan M Roden Jerome I Rotter Igor Rudan Veikko Salomaa Nilesh J Samani Serena Sanna Naveed Sattar Ellen M Schmidt Robert A Scott Peter Sever Raquel S Sevilla Christian M Shaffer Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert V Smith Blair H Smith Sangeetha Somayajula Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kathleen E Stirrups Nathan Stitziel Konstantin Strauch Heather M Stringham Praveen Surendran Hayato Tada Alan R Tall Hua Tang Jean-Claude Tardif Kent D Taylor Stella Trompet Philip S Tsao Jaakko Tuomilehto Anne Tybjaerg-Hansen Natalie R van Zuydam Anette Varbo Tibor V Varga Jarmo Virtamo Melanie Waldenberger Nan Wang Nick J Wareham Helen R Warren Peter E Weeke Joshua Weinstock Jennifer Wessel James G Wilson Peter W F Wilson Ming Xu Hanieh Yaghootkar Robin Young Eleftheria Zeggini He Zhang Neil S Zheng Weihua Zhang Yan Zhang Wei Zhou Yanhua Zhou Magdalena Zoledziewska Joanna M M Howson John Danesh Mark I McCarthy Chad A Cowan Goncalo Abecasis Panos Deloukas Kiran Musunuru Cristen J Willer Sekar Kathiresan

Nat Genet 2017 Dec 30;49(12):1758-1766. Epub 2017 Oct 30.

Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709146PMC
December 2017

Volumetric brain changes in migraineurs from the general population.

Neurology 2017 Nov 11;89(20):2066-2074. Epub 2017 Oct 11.

From the Department of Radiology (I.H.P.-M., E.B.A., S.A, M.A.v.B., M.C.K.) and Department of Neurology (H.K., G.M.T., M.D.F.), Leiden University Medical Center; Department of Neurology (H.K.), Haga Hospital, The Hague, the Netherlands; and Laboratory of Epidemiology, Demography and Biometry (L.J.L.), NIH, Bethesda, MD.

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http://dx.doi.org/10.1212/WNL.0000000000004640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711510PMC
November 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Sex hormones and brain volumes in a longitudinal study of middle-aged men in the CARDIA study.

Brain Behav 2017 10 20;7(10):e00765. Epub 2017 Sep 20.

Laboratory of Epidemiology and Population Science National Institute on Aging Bethesda MD USA.

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http://dx.doi.org/10.1002/brb3.765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651379PMC
October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General Population: The AGES-Reykjavik Study (Age Gene/Environment Susceptibility-Reykjavik Study).

Stroke 2017 09 1;48(9):2353-2360. Epub 2017 Aug 1.

From the Icelandic Heart Association, Kopavogur, Iceland (S.S., T.A., O.K., E.F.G., G.E., V.G.); The University of Iceland, Reykjavik (T.A., P.V.J., V.G.); Department of Radiology, Leiden University Medical Center, the Netherlands (M.A.v.B.); Laboratory of Epidemiology and Population Science, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD (L.J.L.); and Department of Psychology, Reykjavik University, Iceland (M.K.J.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588878PMC
September 2017

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium.

Sci Rep 2017 09 12;7(1):11303. Epub 2017 Sep 12.

Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41598-017-09396-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595875PMC
September 2017

Cardiovascular health in young adulthood and structural brain MRI in midlife: The CARDIA study.

Neurology 2017 Aug 19;89(7):680-686. Epub 2017 Jul 19.

From Northwestern University (M.P.B., N.B.A., D.M.L.-J.), Chicago, IL; Mount Sinai Medical Center Radiology (P.D.), Miami Beach, FL; National Institute on Aging (L.J.L.); National Heart, Lung, and Blood Institute (J.P.R.), Bethesda, MD; Kaiser Permanente Northern California (S.S.), Oakland; University of Mississippi Medical Center (Y.Y.), Jackson; and University of Minnesota (P.J.S.), Minneapolis.

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http://dx.doi.org/10.1212/WNL.0000000000004222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562970PMC
August 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Authors:
Mariaelisa Graff Robert A Scott Anne E Justice Kristin L Young Mary F Feitosa Llilda Barata Thomas W Winkler Audrey Y Chu Anubha Mahajan David Hadley Luting Xue Tsegaselassie Workalemahu Nancy L Heard-Costa Marcel den Hoed Tarunveer S Ahluwalia Qibin Qi Julius S Ngwa Frida Renström Lydia Quaye John D Eicher James E Hayes Marilyn Cornelis Zoltan Kutalik Elise Lim Jian'an Luan Jennifer E Huffman Weihua Zhang Wei Zhao Paula J Griffin Toomas Haller Shafqat Ahmad Pedro M Marques-Vidal Stephanie Bien Loic Yengo Alexander Teumer Albert Vernon Smith Meena Kumari Marie Neergaard Harder Johanne Marie Justesen Marcus E Kleber Mette Hollensted Kurt Lohman Natalia V Rivera John B Whitfield Jing Hua Zhao Heather M Stringham Leo-Pekka Lyytikäinen Charlotte Huppertz Gonneke Willemsen Wouter J Peyrot Ying Wu Kati Kristiansson Ayse Demirkan Myriam Fornage Maija Hassinen Lawrence F Bielak Gemma Cadby Toshiko Tanaka Reedik Mägi Peter J van der Most Anne U Jackson Jennifer L Bragg-Gresham Veronique Vitart Jonathan Marten Pau Navarro Claire Bellis Dorota Pasko Åsa Johansson Søren Snitker Yu-Ching Cheng Joel Eriksson Unhee Lim Mette Aadahl Linda S Adair Najaf Amin Beverley Balkau Juha Auvinen John Beilby Richard N Bergman Sven Bergmann Alain G Bertoni John Blangero Amélie Bonnefond Lori L Bonnycastle Judith B Borja Søren Brage Fabio Busonero Steve Buyske Harry Campbell Peter S Chines Francis S Collins Tanguy Corre George Davey Smith Graciela E Delgado Nicole Dueker Marcus Dörr Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Jessica D Faul Mao Fu Kristine Færch Christian Gieger Sven Gläser Jian Gong Penny Gordon-Larsen Harald Grallert Tanja B Grammer Niels Grarup Gerard van Grootheest Kennet Harald Nicholas D Hastie Aki S Havulinna Dena Hernandez Lucia Hindorff Lynne J Hocking Oddgeir L Holmens Christina Holzapfel Jouke Jan Hottenga Jie Huang Tao Huang Jennie Hui Cornelia Huth Nina Hutri-Kähönen Alan L James John-Olov Jansson Min A Jhun Markus Juonala Leena Kinnunen Heikki A Koistinen Ivana Kolcic Pirjo Komulainen Johanna Kuusisto Kirsti Kvaløy Mika Kähönen Timo A Lakka Lenore J Launer Benjamin Lehne Cecilia M Lindgren Mattias Lorentzon Robert Luben Michel Marre Yuri Milaneschi Keri L Monda Grant W Montgomery Marleen H M De Moor Antonella Mulas Martina Müller-Nurasyid A W Musk Reija Männikkö Satu Männistö Narisu Narisu Matthias Nauck Jennifer A Nettleton Ilja M Nolte Albertine J Oldehinkel Matthias Olden Ken K Ong Sandosh Padmanabhan Lavinia Paternoster Jeremiah Perez Markus Perola Annette Peters Ulrike Peters Patricia A Peyser Inga Prokopenko Hannu Puolijoki Olli T Raitakari Tuomo Rankinen Laura J Rasmussen-Torvik Rajesh Rawal Paul M Ridker Lynda M Rose Igor Rudan Cinzia Sarti Mark A Sarzynski Kai Savonen William R Scott Serena Sanna Alan R Shuldiner Steve Sidney Günther Silbernagel Blair H Smith Jennifer A Smith Harold Snieder Alena Stančáková Barbara Sternfeld Amy J Swift Tuija Tammelin Sian-Tsung Tan Barbara Thorand Dorothée Thuillier Liesbeth Vandenput Henrik Vestergaard Jana V van Vliet-Ostaptchouk Marie-Claude Vohl Uwe Völker Gérard Waeber Mark Walker Sarah Wild Andrew Wong Alan F Wright M Carola Zillikens Niha Zubair Christopher A Haiman Loic Lemarchand Ulf Gyllensten Claes Ohlsson Albert Hofman Fernando Rivadeneira André G Uitterlinden Louis Pérusse James F Wilson Caroline Hayward Ozren Polasek Francesco Cucca Kristian Hveem Catharina A Hartman Anke Tönjes Stefania Bandinelli Lyle J Palmer Sharon L R Kardia Rainer Rauramaa Thorkild I A Sørensen Jaakko Tuomilehto Veikko Salomaa Brenda W J H Penninx Eco J C de Geus Dorret I Boomsma Terho Lehtimäki Massimo Mangino Markku Laakso Claude Bouchard Nicholas G Martin Diana Kuh Yongmei Liu Allan Linneberg Winfried März Konstantin Strauch Mika Kivimäki Tamara B Harris Vilmundur Gudnason Henry Völzke Lu Qi Marjo-Riitta Järvelin John C Chambers Jaspal S Kooner Philippe Froguel Charles Kooperberg Peter Vollenweider Göran Hallmans Torben Hansen Oluf Pedersen Andres Metspalu Nicholas J Wareham Claudia Langenberg David R Weir David J Porteous Eric Boerwinkle Daniel I Chasman Gonçalo R Abecasis Inês Barroso Mark I McCarthy Timothy M Frayling Jeffrey R O'Connell Cornelia M van Duijn Michael Boehnke Iris M Heid Karen L Mohlke David P Strachan Caroline S Fox Ching-Ti Liu Joel N Hirschhorn Robert J Klein Andrew D Johnson Ingrid B Borecki Paul W Franks Kari E North L Adrienne Cupples Ruth J F Loos Tuomas O Kilpeläinen

PLoS Genet 2017 Aug 23;13(8):e1006972. Epub 2017 Aug 23.

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http://dx.doi.org/10.1371/journal.pgen.1006972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567921PMC
August 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Authors:
Louise V Wain Ahmad Vaez Rick Jansen Roby Joehanes Peter J van der Most A Mesut Erzurumluoglu Paul F O'Reilly Claudia P Cabrera Helen R Warren Lynda M Rose Germaine C Verwoert Jouke-Jan Hottenga Rona J Strawbridge Tonu Esko Dan E Arking Shih-Jen Hwang Xiuqing Guo Zoltan Kutalik Stella Trompet Nick Shrine Alexander Teumer Janina S Ried Joshua C Bis Albert V Smith Najaf Amin Ilja M Nolte Leo-Pekka Lyytikäinen Anubha Mahajan Nicholas J Wareham Edith Hofer Peter K Joshi Kati Kristiansson Michela Traglia Aki S Havulinna Anuj Goel Mike A Nalls Siim Sõber Dragana Vuckovic Jian'an Luan Fabiola Del Greco M Kristin L Ayers Jaume Marrugat Daniela Ruggiero Lorna M Lopez Teemu Niiranen Stefan Enroth Anne U Jackson Christopher P Nelson Jennifer E Huffman Weihua Zhang Jonathan Marten Ilaria Gandin Sarah E Harris Tatijana Zemunik Yingchang Lu Evangelos Evangelou Nabi Shah Martin H de Borst Massimo Mangino Bram P Prins Archie Campbell Ruifang Li-Gao Ganesh Chauhan Christopher Oldmeadow Gonçalo Abecasis Maryam Abedi Caterina M Barbieri Michael R Barnes Chiara Batini John Beilby Tineka Blake Michael Boehnke Erwin P Bottinger Peter S Braund Morris Brown Marco Brumat Harry Campbell John C Chambers Massimiliano Cocca Francis Collins John Connell Heather J Cordell Jeffrey J Damman Gail Davies Eco J de Geus Renée de Mutsert Joris Deelen Yusuf Demirkale Alex S F Doney Marcus Dörr Martin Farrall Teresa Ferreira Mattias Frånberg He Gao Vilmantas Giedraitis Christian Gieger Franco Giulianini Alan J Gow Anders Hamsten Tamara B Harris Albert Hofman Elizabeth G Holliday Jennie Hui Marjo-Riitta Jarvelin Åsa Johansson Andrew D Johnson Pekka Jousilahti Antti Jula Mika Kähönen Sekar Kathiresan Kay-Tee Khaw Ivana Kolcic Seppo Koskinen Claudia Langenberg Marty Larson Lenore J Launer Benjamin Lehne David C M Liewald Li Lin Lars Lind François Mach Chrysovalanto Mamasoula Cristina Menni Borbala Mifsud Yuri Milaneschi Anna Morgan Andrew D Morris Alanna C Morrison Peter J Munson Priyanka Nandakumar Quang Tri Nguyen Teresa Nutile Albertine J Oldehinkel Ben A Oostra Elin Org Sandosh Padmanabhan Aarno Palotie Guillaume Paré Alison Pattie Brenda W J H Penninx Neil Poulter Peter P Pramstaller Olli T Raitakari Meixia Ren Kenneth Rice Paul M Ridker Harriëtte Riese Samuli Ripatti Antonietta Robino Jerome I Rotter Igor Rudan Yasaman Saba Aude Saint Pierre Cinzia F Sala Antti-Pekka Sarin Reinhold Schmidt Rodney Scott Marc A Seelen Denis C Shields David Siscovick Rossella Sorice Alice Stanton David J Stott Johan Sundström Morris Swertz Kent D Taylor Simon Thom Ioanna Tzoulaki Christophe Tzourio André G Uitterlinden Uwe Völker Peter Vollenweider Sarah Wild Gonneke Willemsen Alan F Wright Jie Yao Sébastien Thériault David Conen John Attia Peter Sever Stéphanie Debette Dennis O Mook-Kanamori Eleftheria Zeggini Tim D Spector Pim van der Harst Colin N A Palmer Anne-Claire Vergnaud Ruth J F Loos Ozren Polasek John M Starr Giorgia Girotto Caroline Hayward Jaspal S Kooner Cecila M Lindgren Veronique Vitart Nilesh J Samani Jaakko Tuomilehto Ulf Gyllensten Paul Knekt Ian J Deary Marina Ciullo Roberto Elosua Bernard D Keavney Andrew A Hicks Robert A Scott Paolo Gasparini Maris Laan YongMei Liu Hugh Watkins Catharina A Hartman Veikko Salomaa Daniela Toniolo Markus Perola James F Wilson Helena Schmidt Jing Hua Zhao Terho Lehtimäki Cornelia M van Duijn Vilmundur Gudnason Bruce M Psaty Annette Peters Rainer Rettig Alan James J Wouter Jukema David P Strachan Walter Palmas Andres Metspalu Erik Ingelsson Dorret I Boomsma Oscar H Franco Murielle Bochud Christopher Newton-Cheh Patricia B Munroe Paul Elliott Daniel I Chasman Aravinda Chakravarti Joanne Knight Andrew P Morris Daniel Levy Martin D Tobin Harold Snieder Mark J Caulfield Georg B Ehret

Hypertension 2017 Jul 24. Epub 2017 Jul 24.

From the Department of Health Sciences (L.V.W., A.M.E., N. Shrine, C.B., T.B., M.D.T.), and Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre (C.P.N., P.S.B., N.J.S.), University of Leicester, United Kingdom; Department of Epidemiology (A.V., P.J.v.d.M., I.M.N., H. Snieder), Division of Nephrology, Department of Internal Medicine (M.H.d.B., M.A.S.), Interdisciplinary Center Psychopathology and Emotion Regulation (IPCE) (A.J.O., H.R., C.A.H.), Department of Genetics, (M.S.), and Department of Cardiology (P.v.d.H.), University of Groningen, University Medical Center Groningen, The Netherlands; Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Iran (A.V.); Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, The Netherlands (R. Jansen); Hebrew SeniorLife, Harvard Medical School, Boston, MA (R. Joehanes); National Heart, Lung and Blood Institute's Framingham Heart Study, MA (R. Joehanes, A.D.J., M. Larson); Institute of Psychiatry, Psychology and Neuroscience (P.F.O.), and Department of Twin Research and Genetic Epidemiology (M.M., C. Menni, T.D.S.), King's College London, United Kingdom; Clinical Pharmacology, William Harvey Research Institute (C.P.C., H.R.W., M.R.B., M. Brown, B.M., M.R., P.B.M., M.J.C.) and NIHR Barts Cardiovascular Biomedical Research Unit (C.P.C., H.R.W., M.R.B., M. Brown, P.B.M., M.J.C.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA (L.M.R., F.G., P.M.R., D.I.C.); Department of Epidemiology (G.C.V., A. Hofman, A.G.U., O.H.F.), Genetic Epidemiology Unit, Department of Epidemiology (N.A., B.A.O., C.M.v.D.), and Department of Internal Medicine (A.G.U.), Erasmus MC, Rotterdam, The Netherlands; Department of Biological Psychology, Vrije Universiteit, Amsterdam, EMGO+ Institute, VU University Medical Center, The Netherlands (J.-J.H., E.J.d.G., G.W., D.I.B.); Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden (R.J.S., M. Frånberg, A. Hamsten); Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden (R.J.S., M. Frånberg, A. Hamsten); Estonian Genome Center (T.E., E.O., A. Metspalu), Institute of Biomedicine and Translational Medicine (S.S., M. Laan), and Estonian Genome Center (M.P.), University of Tartu, Estonia; Divisions of Endocrinology/Children's Hospital, Boston, MA (T.E.); Broad Institute of Harvard and MIT, Cambridge, MA (T.E., C.M.L., C.N.-C.); Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (D.E.A., P.N., A. Chakravarti, G.B.E.); The Population Science Branch, Division of Intramural Research, National Heart Lung and Blood Institute (S.-J.H., D.L.), Laboratory of Neurogenetics, National Institute on Aging (M.A.N.), Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute (F.C.), and Center for Information Technology (Y.D., P.J.M., Q.T.N.), National Institutes of Health, Bethesda, MD; The Framingham Heart Study, Framingham, MA (S.-J.H., D.L.); The Institute for Translational Genomics and Population Sciences, Department of Pediatrics (X.G., J.Y.), and The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine (J.I.R.), LABioMed at Harbor-UCLA Medical Center, Torrance, CA; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland (Z.K., M. Bochud); Swiss Institute of Bioinformatics, Lausanne, Switzerland (Z.K.); Department of Cardiology (S. Trompet, J.W.J.) Department of Gerontology and Geriatrics (S. Trompet), Department of Clinical Epidemiology (R.L.-G., R.d.M., D.O.M.-K.), Department of Molecular Epidemiology (J.D.), and Department of Public Health and Primary Care (D.O.M.-K.), Leiden University Medical Center, The Netherlands; Institute for Community Medicine (A.T.), Department of Internal Medicine B (M.D.), and Interfaculty Institute for Genetics and Functional Genomics (U.V.), University Medicine Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Germany (A.T., M.D., U.V.); Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg, Germany (J.S.R., A. Peters); Cardiovascular Health Research Unit, Department of Medicine (J.C.B., B.M.P.) and Departments of Biostatistics (K.R.), Epidemiology (B.M.P.), and Health Services (B.M.P.), University of Washington, Seattle; Icelandic Heart Association, Kopavogur, Iceland (A.V.S., V. Gudnason); Faculty of Medicine, University of Iceland, Reykjavik, Iceland (A.V.S., V. Gudnason); Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., T.L.); Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Finland (L.-P.L., T.L.); Wellcome Trust Centre for Human Genetics (A. Mahajan, A.G., M. Farrall, T.F., C.M.L., H.W., A.P.M.), and Division of Cardiovascular Medicine, Radcliffe Department of Medicine (A.G., M. Farrall, H.W.), University of Oxford, United Kingdom; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, United Kingdom (N.J.W., J.L., C.L., R.J.F.L., R.A.S., J.H.Z.); Clinical Division of Neurogeriatrics, Department of Neurology (E.H., R. Schmidt), Institute of Medical Informatics, Statistics and Documentation (E.H.), and Department of Neurology (H. Schmidt), Medical University Graz, Austria; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics (P.K.J., H.C., I.R., S.W., J.F.W.), Centre for Cognitive Ageing and Cognitive Epidemiology (L.M.L., S.E.H., G.D., A.J.G., D.C.M.L., J.M.S., I.J.D.), Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine (A. Campbell), Generation Scotland, Centre for Genomic and Experimental Medicine (A. Campbell, S.P., C.H.), Department of Psychology (G.D., D.C.M.L., A. Pattie, I.J.D.), Alzheimer Scotland Dementia Research Centre (J.M.S.), and Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (C.H.), University of Edinburgh, Scotland, United Kingdom; Department of Health (K.K., A.S.H., T. Niiranen, P.J., A.J., S. Koskinen, P.K., V.S., M.P.), and Chronic Disease Prevention Unit (J.T.), National Institute for Health and Welfare (THL), Helsinki, Finland; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy (M.T., C.M.B., C.F.S., D.T.); Data Tecnica International, Glen Echo, MD (M.A.N.); Medical Genetics, IRCCS-Burlo Garofolo Children Hospital, Trieste, Italy (D.V., G.G., P.G.); Department of Medical, Surgical and Health Sciences, University of Trieste, Italy (D.V., I.G., M. Brumat, M. Cocca, A. Morgan, G.G., P.G.); Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, Italy (F.D.G.M., P.P.P., A.S.P., A.A.H.); Department of Genetics and Genomic Sciences (K.L.A.), The Charles Bronfman Institute for Personalized Medicine (Y.L., E.P.B., R.J.F.L.), and Mindich Child health Development Institute (R.J.F.L.), Icahn School of Medicine at Mount Sinai, New York; Cardiovascular Epidemiology and Genetics, IMIM, and CIBERCV, Barcelona, Spain (J. Marrugat, R.E.); Institute of Genetics and Biophysics A. Buzzati-Traverso, CNR, Napoli, Italy (D.R., T. Nutile, R. Sorice, M. Ciullo); Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin (L.M.L.); UCD Conway Institute, Centre for Proteome Research (L.M.L.), and School of Medicine, Conway Institute (D.C.S.), University College Dublin, Belfield, Ireland; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Sweden (S.E., Å. Johansson, U.G.); Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor (A.U.J., M. Boehnke); NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester United Kingdom (C.P.N., P.S.B., N.J.S.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.E.H., V.V., J. Marten, A.F.W., J.F.W.), and Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine (S.E.H.), University of Edinburgh, Western General Hospital, Scotland, United Kingdom; Department of Epidemiology and Biostatistics, School of Public Health (W.Z., E.E., J.C.C., H.G., B.L., I.T., A.-C.V.), MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health (M.-R.J., P.E.), School of Public Health (N.P.), International Centre for Circulatory Health (S. Thom), and National Heart and Lung Institute (P.S.), Imperial College London, United Kingdom; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Southall, United Kingdom (W.Z., J.C.C., J.S.K.); Department of Medical Biology, Faculty of Medicine, University of Split, Croatia (T.Z.); Department of Hygiene and Epidemiology, University of Ioannina Medical School, Greece (E.E.); Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Scotland, United Kingdom (N. Shah, A.S.F.D., C.N.A.P.); Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan (N. Shah); National Institute for Health Research Biomedical Research Centre, London, United Kingdom (M.M.); Department of Human Genetics, Wellcome Trust Sanger Institute, United Kingdom (B.P.P., E.Z.); INSERM U 1219, Bordeaux Population Health Center, France (G.C., C.T., S.D.); Bordeaux University, France (G.C., C.T., S.D.); Hunter Medical Research Institute, New Lambton, NSW, Australia (C.O., E.G.H., R. Scott, J.A.); Center for Statistical Genetics, Department of Biostatistics, Ann Arbor, MI (G.A.); Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Iran (M.A.); Busselton Population Medical Research Institute, Western Australia (J.B., J.H.); PathWest Laboratory Medicine of Western Australia, Nedlands (J.B., J.H.); School of Pathology and Laboratory Medicine (J.B., J.H.), School of Population and Global Health (J.H.), and School of Medicine and Pharmacology (A. James), The University of Western Australia, Nedlands; Imperial College Healthcare NHS Trust, London, United Kingdom (J.C.C., J.S.K.); University of Dundee, Ninewells Hospital & Medical School, United Kingdom (J.C.); Institute of Genetic Medicine (H.J.C.), and Institute of Health and Society (C. Mamasoula), Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Pathology, Amsterdam Medical Center, The Netherlands (J.J.D.); Department of Numerical Analysis and Computer Science, Stockholm University, Sweden (M. Frånberg); Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden (V. Giedraitis); Helmholtz Zentrum Muenchen, Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH), Neuherberg, Germany (C.G.); Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, United Kingdom (A.J.G.); Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging (T.B.H., L.J.L.); Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (A. Hofman); Center For Life-Course Health Research (M.-R.J.), and Biocenter Oulu (M.-R.J.), University of Oulu, Finland; Unit of Primary Care, Oulu University Hospital, Finland (M.-R.J.); National Heart, Lung and Blood Institute, Cardiovascular Epidemiology and Human Genomics Branch, Bethesda, MD (A.D.J.); Department of Clinical Physiology, Tampere University Hospital, Finland (M.K.); Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Finland (M.K.); Cardiovascular Research Center (S. Kathiresan, C.N.-C.); Center for Human Genetics (S. Kathiresan), and Center for Human Genetic Research (C.N.-C.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (S. Kathiresan, C.N.-C.); Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, United Kingdom (K.-T.K.); Department of Public Health, Faculty of Medicine, University of Split, Croatia (I.K., O.P.); Cardiology, Department of Specialties of Medicine, Geneva University Hospital, Switzerland (L. Lin, F.M., G.B.E.); Department of Medical Sciences, Cardiovascular Epidemiology (L. Lind, J.S.), and Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory (E.I.), Uppsala University, Sweden; Department of Psychiatry, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands (Y.M., B.W.J.H.P.); School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, Scotland, United Kingdom (A.D.M.); Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston (A.C.M.); British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences (S.P.), and Institute of Cardiovascular and Medical Sciences, Faculty of Medicine (D.J.S.), University of Glasgow, United Kingdom; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland (A. Palotie, S.R., A.-P.S., M.P.); Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada (G.P., S. Thériault); Department of Neurology, General Central Hospital, Bolzano, Italy (P.P.P.); Department of Neurology, University of Lübeck, Germany (P.P.P.); Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland (O.T.R.); Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (O.T.R.); Department of Cardiology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China (M.R.); Harvard Medical School, Boston, MA (P.M.R., D.I.C.); Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy (A.R.); Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Austria (Y.S., H. Schmidt); INSERM U1078, Etablissement Français du Sang, Brest Cedex, France (A.S.P.); Faculty of Health, University of Newcastle, Callaghan, NSW, Australia (R. Scott, J.A.); John Hunter Hospital, New Lambton, NSW, Australia (R. Scott, J.A.); The New York Academy of Medicine, New York (D.S.); IRCCS Neuromed, Pozzilli, Isernia, Italy (R. Sorice, M. Ciullo); Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland (A.S.); Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (K.D.T.); Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA (K.D.T.); Department of Public Health (C.T.), and Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Internal Medicine, Lausanne University Hospital, CHUV, Switzerland (P.V.); Population Health Research Institute, McMaster University, Hamilton Ontario, Canada (D.C.); National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, United Kingdom (J.S.K.); Dasman Diabetes Institute, Kuwait (J.T.); Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia (J.T.); Department of Neurosciences and Preventive Medicine, Danube-University Krems, Austria (J.T.); Division of Cardiovascular Sciences, The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust, United Kingdom (B.D.K.); Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem (Y.M.L.); Kaiser Permanent Washington Health Research Institute, Seattle, WA (B.M.P.); Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany (R.R); Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Nedlands, Western Australia (A. James); Population Health Research Institute, St George's, University of London, United Kingdom (D.P.S.); Department of Medicine, Columbia University Medical Center, New York (W.P.); Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA (E.I.); Data Science Institute and Lancaster Medical School, Lancaster University, United Kingdom (J.K.); and Department of Biostatistics, University of Liverpool, United Kingdom (A.P.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783787PMC
July 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 07;49(8):1286

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July 2017

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.

Authors:
Mathias Gorski Peter J van der Most Alexander Teumer Audrey Y Chu Man Li Vladan Mijatovic Ilja M Nolte Massimiliano Cocca Daniel Taliun Felicia Gomez Yong Li Bamidele Tayo Adrienne Tin Mary F Feitosa Thor Aspelund John Attia Reiner Biffar Murielle Bochud Eric Boerwinkle Ingrid Borecki Erwin P Bottinger Ming-Huei Chen Vincent Chouraki Marina Ciullo Josef Coresh Marilyn C Cornelis Gary C Curhan Adamo Pio d' Adamo Abbas Dehghan Laura Dengler Jingzhong Ding Gudny Eiriksdottir Karlhans Endlich Stefan Enroth Tõnu Esko Oscar H Franco Paolo Gasparini Christian Gieger Giorgia Girotto Omri Gottesman Vilmundur Gudnason Ulf Gyllensten Stephen J Hancock Tamara B Harris Catherine Helmer Simon Höllerer Edith Hofer Albert Hofman Elizabeth G Holliday Georg Homuth Frank B Hu Cornelia Huth Nina Hutri-Kähönen Shih-Jen Hwang Medea Imboden Åsa Johansson Mika Kähönen Wolfgang König Holly Kramer Bernhard K Krämer Ashish Kumar Zoltan Kutalik Jean-Charles Lambert Lenore J Launer Terho Lehtimäki Martin H de Borst Gerjan Navis Morris Swertz Yongmei Liu Kurt Lohman Ruth J F Loos Yingchang Lu Leo-Pekka Lyytikäinen Mark A McEvoy Christa Meisinger Thomas Meitinger Andres Metspalu Marie Metzger Evelin Mihailov Paul Mitchell Matthias Nauck Albertine J Oldehinkel Matthias Olden Brenda Wjh Penninx Giorgio Pistis Peter P Pramstaller Nicole Probst-Hensch Olli T Raitakari Rainer Rettig Paul M Ridker Fernando Rivadeneira Antonietta Robino Sylvia E Rosas Douglas Ruderfer Daniela Ruggiero Yasaman Saba Cinzia Sala Helena Schmidt Reinhold Schmidt Rodney J Scott Sanaz Sedaghat Albert V Smith Rossella Sorice Benedicte Stengel Sylvia Stracke Konstantin Strauch Daniela Toniolo Andre G Uitterlinden Sheila Ulivi Jorma S Viikari Uwe Völker Peter Vollenweider Henry Völzke Dragana Vuckovic Melanie Waldenberger Jie Jin Wang Qiong Yang Daniel I Chasman Gerard Tromp Harold Snieder Iris M Heid Caroline S Fox Anna Köttgen Cristian Pattaro Carsten A Böger Christian Fuchsberger

Sci Rep 2017 05 26;7:46835. Epub 2017 May 26.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445557PMC
May 2017

Dietary supplement use in the older population of Iceland and association with mortality.

Br J Nutr 2017 May 13;117(10):1463-1469. Epub 2017 Jun 13.

1Unit for Nutrition Research,School of Health Sciences,University of Iceland and Landspitali University Hospital,Eiríksgata 29,101 Reykjavik,Iceland.

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http://dx.doi.org/10.1017/S0007114517001313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901758PMC
May 2017