Publications by authors named "Lennart Opitz"

66Publications

Increased Antibody Response to Fucosylated Oligosaccharides and Fucose-Carrying Species in Crohn's Disease.

Front Microbiol 2020 14;11:1553. Epub 2020 Jul 14.

Institute of Physiology, University of Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2020.01553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381230PMC
July 2020

Recurrent inflammatory disease caused by a heterozygous mutation in CD48.

J Allergy Clin Immunol 2019 11 13;144(5):1441-1445.e17. Epub 2019 Aug 13.

Division of Immunology, University Children's Hospital Zurich, Zurich, Switzerland; University of Zurich, Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2019.07.038DOI Listing
November 2019

Transcriptome Profiling of Primary Skin Fibroblasts Reveal Distinct Molecular Features Between - and -Kyphoscoliotic Ehlers-Danlos Syndrome.

Genes (Basel) 2019 07 8;10(7). Epub 2019 Jul 8.

Connective Tissue Unit, Division of Metabolism and Children's Research Centre, University Children's Hospital, 8032 Zürich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/genes10070517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678841PMC
July 2019

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs.

Proc Natl Acad Sci U S A 2019 05 6;116(21):10547-10556. Epub 2019 May 6.

Laboratory of Translational Nutrition Biology, Department of Health Sciences and Technology, ETH Zurich, 8603 Schwerzenbach, Switzerland;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1820810116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534971PMC
May 2019

Gene expression signatures of circulating human type 1, 2, and 3 innate lymphoid cells.

J Allergy Clin Immunol 2019 06 28;143(6):2321-2325. Epub 2019 Feb 28.

Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2019.01.047DOI Listing
June 2019

Long fragments achieve lower base quality in Illumina paired-end sequencing.

Sci Rep 2019 02 27;9(1):2856. Epub 2019 Feb 27.

Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-019-39076-7
Publisher Site
http://dx.doi.org/10.1038/s41598-019-39076-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393434PMC
February 2019

The L cell transcriptome is unaffected by vertical sleeve gastrectomy but highly dependent upon position within the gastrointestinal tract.

Peptides 2019 03 17;113:22-34. Epub 2019 Jan 17.

Laboratory of Organic Chemistry, ETH Zurich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01969781193000
Publisher Site
http://dx.doi.org/10.1016/j.peptides.2019.01.001DOI Listing
March 2019

MHC-II Deficiency Among Egyptians: Novel Mutations and Unique Phenotypes.

J Allergy Clin Immunol Pract 2019 03 28;7(3):856-863. Epub 2018 Aug 28.

Pediatrics Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaip.2018.07.046DOI Listing
March 2019

Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes.

J Allergy Clin Immunol 2019 01 14;143(1):292-304.e8. Epub 2018 Jun 14.

Division of Immunology, University Children's Hospital Zurich, Zurich, Switzerland; Pediatric Immunology, University of Zurich, Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2018.02.057DOI Listing
January 2019

An optimised protocol for isolation of RNA from small sections of laser-capture microdissected FFPE tissue amenable for next-generation sequencing.

BMC Mol Biol 2017 08 23;18(1):22. Epub 2017 Aug 23.

Institute of Veterinary Pharmacology and Toxicology, Vetsuisse Faculty, University of Zürich, Winterthurerstr. 260, 8057, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12867-017-0099-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569520PMC
August 2017

Effects of oral antibiotics and isotretinoin on the murine gut microbiota.

Int J Antimicrob Agents 2017 Sep 6;50(3):342-351. Epub 2017 Jul 6.

Division of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijantimicag.2017.03.017DOI Listing
September 2017

SRF and MKL1 Independently Inhibit Brown Adipogenesis.

PLoS One 2017 26;12(1):e0170643. Epub 2017 Jan 26.

Swiss Federal Institute of Technology, ETH Zürich, Institute of Food Nutrition and Health, Schwerzenbach, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170643PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268445PMC
August 2017

Diurnal changes in the histone H3 signature H3K9ac|H3K27ac|H3S28p are associated with diurnal gene expression in Arabidopsis.

Plant Cell Environ 2016 11 30;39(11):2557-2569. Epub 2016 Sep 30.

Department of Biology, ETH Zurich, Zurich, 8092, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pce.12811DOI Listing
November 2016

SUSHI: an exquisite recipe for fully documented, reproducible and reusable NGS data analysis.

BMC Bioinformatics 2016 Jun 2;17(1):228. Epub 2016 Jun 2.

Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Winterthurerstrasse. 190, 8057, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-016-1104-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890512PMC
June 2016

Global analysis of asymmetric RNA enrichment in oocytes reveals low conservation between closely related Xenopus species.

Mol Biol Cell 2015 Nov 2;26(21):3777-87. Epub 2015 Sep 2.

Institute of Developmental Biochemistry, University Medical Center Göttingen, 37077 Göttingen, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E15-02-0115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626063PMC
November 2015

Genome-wide identification of CBX2 targets: insights in the human sex development network.

Mol Endocrinol 2015 Feb 8;29(2):247-57. Epub 2015 Jan 8.

Division of Endocrinology (W.E., A.B.-L.), Department of Medicine, University of Fribourg, 1700 Fribourg, Switzerland; and Functional Genomics Center Zurich (L.O.), University of Zurich/ETHZ, 8057 Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2014-1339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414760PMC
February 2015

Tissue-specific transcriptomics, chromosomal localization, and phylogeny of chemosensory and odorant binding proteins from the red flour beetle Tribolium castaneum reveal subgroup specificities for olfaction or more general functions.

BMC Genomics 2014 Dec 18;15:1141. Epub 2014 Dec 18.

Department of Developmental Biology, Georg-August-University Goettingen, Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, GZMB, Ernst-Caspari-Haus, Justus-von-Liebig-Weg 11, Goettingen 37077, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-15-1141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377858PMC
December 2014

Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques.

BMC Genomics 2014 Jun 5;15:434. Epub 2014 Jun 5.

Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-15-434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061447PMC
June 2014

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance.

Hum Genet 2014 Aug 13;133(8):997-1009. Epub 2014 Apr 13.

Institute of Human Genetics, University Medical Center Göttingen, Heinrich-Düker-Weg 12, 37073, Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-014-1444-2DOI Listing
August 2014

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

Cancer Res 2014 May 13;74(9):2604-16. Epub 2014 Jan 13.

Authors' Affiliations: Clinical Cooperation Unit Pediatric Oncology; Departments of Biostatistics and Tumor Genetics; Clinical Cooperation Unit Neuropathology; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ); Departments of Neuropathology and Pediatric Hematology and Oncology, University of Heidelberg, Heidelberg; Transcriptome Analysis Laboratory, University of Goettingen, Goettingen; St. Lukas Klinik Solingen, Solingen; Department of Pediatric Hematology and Oncology; and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-13-1904DOI Listing
May 2014

Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching.

BMC Bioinformatics 2013 Dec 24;14:370. Epub 2013 Dec 24.

Functional Genomics Center Zurich, University of Zurich/ETH, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-14-370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879183PMC
December 2013

Valproic acid inhibits the proliferation of cancer cells by re-expressing cyclin D2.

Carcinogenesis 2013 May 24;34(5):1115-24. Epub 2013 Jan 24.

Institute of Human Genetics, University Medical Center Göttingen, 37073 Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgt019DOI Listing
May 2013

Transcriptional repression of Hox genes by C. elegans HP1/HPL and H1/HIS-24.

PLoS Genet 2012 Sep 13;8(9):e1002940. Epub 2012 Sep 13.

Department of Genes and Behavior, Epigenetics in C elegans Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pgen.1002940
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1002940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441639PMC
September 2012

Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome.

Neurobiol Dis 2012 Oct 30;48(1):102-14. Epub 2012 Jun 30.

DFG Research Center Molecular Physiology of the Brain (CMPB), Zentrum für Physiologie und Pathophysiologie, Abteilung Neuro- und Sinnesphysiologie, Georg-August-Universität Göttingen, Universitätsmedizin, Humboldtallee 23, D-37073 Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2012.06.007DOI Listing
October 2012

Amyloid precursor protein is a biomarker for transformed human pluripotent stem cells.

Am J Pathol 2012 Apr 1;180(4):1636-52. Epub 2012 Feb 1.

Division of Molecular Psychiatry, Department of Psychiatry, University Medicine Goettingen, Goettingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2011.12.015DOI Listing
April 2012

Control of oligodendroglial cell number by the miR-17-92 cluster.

Development 2010 Jul 26;137(13):2127-32. Epub 2010 May 26.

Max Planck Institute for Experimental Medicine, Hermann-Rein-Strasse 3, D-37075 Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.050633DOI Listing
July 2010

A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data.

Comput Methods Programs Biomed 2010 Nov 10;100(2):132-9. Epub 2010 Apr 10.

Department of Medical Statistics, University Medicine Göttingen, 37099 Göttingen, Germany.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01692607100006
Publisher Site
http://dx.doi.org/10.1016/j.cmpb.2010.03.016DOI Listing
November 2010

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease.

Mol Neurodegener 2009 Aug 27;4:36. Epub 2009 Aug 27.

Department of Infection Models, German Primate Center, Kellnerweg 4, 37077 Goettingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1750-1326-4-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743691PMC
August 2009

Identification of Tmem10/Opalin as a novel marker for oligodendrocytes using gene expression profiling.

BMC Neurosci 2008 Apr 25;9:40. Epub 2008 Apr 25.

Centre for Biochemistry and Molecular Cell Biology, University of Göttingen Humboldtallee 23, Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2202-9-40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396630PMC
April 2008

Semi-supervised learning for the identification of syn-expressed genes from fused microarray and in situ image data.

BMC Bioinformatics 2007 ;8 Suppl 10:S3

Department Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/1471-2105-8-S10-S3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230504PMC
April 2008

CPA6, FMO2, LGI1, SIAT1 and TNC are differentially expressed in early- and late-stage oral squamous cell carcinoma--a pilot study.

Oral Oncol 2008 Oct 29;44(10):941-8. Epub 2008 Jan 29.

Department of Oral and Maxillofacial Surgery, University of Goettingen, Robert-Koch-Strasse 40, D-37099 Goettingen, Germany.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S136883750700301
Publisher Site
http://dx.doi.org/10.1016/j.oraloncology.2007.10.011DOI Listing
October 2008

Gene regulation by homeobox transcription factor Prox1 in murine hepatoblasts.

Cell Tissue Res 2007 Nov 9;330(2):209-20. Epub 2007 Sep 9.

Children's Hospital, Pediatrics I, Georg August University, Robert-Koch-Strasse 40, 37075, Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00441-007-0477-4DOI Listing
November 2007