Leng Han

Leng Han

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Leng Han

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Anticancer activity of green synthesised gold nanoparticles from inhibits A549 cell proliferation through the apoptotic pathway.

Artif Cells Nanomed Biotechnol 2019 Dec;47(1):4012-4019

Department of Hematology and Oncology, China-Japan Union Hospital of Jilin University , Changchun , Jilin Province , China.

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http://dx.doi.org/10.1080/21691401.2019.1575844DOI Listing
December 2019

Metabolite Profiling Leads to the Development of an RNA Interference Strain for .

G3 (Bethesda) 2019 Nov 11. Epub 2019 Nov 11.

Baylor College of Medicine; Howard Hughes Medical Institute

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http://dx.doi.org/10.1534/g3.119.400741DOI Listing
November 2019

Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment.

BMC Biol 2019 11 13;17(1):89. Epub 2019 Nov 13.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 North Lishi Road, Beijing, 100037, People's Republic of China.

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http://dx.doi.org/10.1186/s12915-019-0709-6DOI Listing
November 2019

Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development.

J Clin Invest 2019 Oct 28. Epub 2019 Oct 28.

Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI127721DOI Listing
October 2019

APAatlas: decoding alternative polyadenylation across human tissues.

Nucleic Acids Res 2019 Oct 5. Epub 2019 Oct 5.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/nar/gkz876DOI Listing
October 2019

Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer.

Nat Commun 2019 Oct 8;10(1):4562. Epub 2019 Oct 8.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-019-12543-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783481PMC
October 2019

Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo.

Heliyon 2019 Oct 1;5(10):e02739. Epub 2019 Nov 1.

School of Stomatology, Southern Medical University, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, PR China.

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http://dx.doi.org/10.1016/j.heliyon.2019.e02739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838904PMC
October 2019

Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality.

FASEB J 2019 Sep 29;33(9):10528-10537. Epub 2019 Jun 29.

Department of Biochemistry and Molecular Biology, The University of Texas McGovern Medical School, Houston, Texas, USA.

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http://dx.doi.org/10.1096/fj.201900246RRDOI Listing
September 2019

Long noncoding RNA MNX1-AS1 contributes to lung cancer progression through the miR-527/BRF2 pathway.

J Cell Physiol 2019 Aug 7;234(8):13843-13850. Epub 2019 Jan 7.

Department of Thoracic Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.

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http://doi.wiley.com/10.1002/jcp.28064
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http://dx.doi.org/10.1002/jcp.28064DOI Listing
August 2019

Molecular Treasures of Cancer Cell Lines.

Trends Mol Med 2019 Aug 26;25(8):657-659. Epub 2019 Jun 26.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Center for Precision Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2019.06.002DOI Listing
August 2019

tRic: a user-friendly data portal to explore the expression landscape of tRNAs in human cancers.

RNA Biol 2019 Aug 25:1-6. Epub 2019 Aug 25.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston , Houston , TX , USA.

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http://dx.doi.org/10.1080/15476286.2019.1657744DOI Listing
August 2019

Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines.

Genome Med 2019 08 26;11(1):55. Epub 2019 Aug 26.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s13073-019-0663-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709551PMC
August 2019

Impact of intravascular ultrasound-guided drug-eluting stent implantation on patients with chronic kidney disease: Results from ULTIMATE trial.

Catheter Cardiovasc Interv 2019 Jun 22;93(7):1184-1193. Epub 2019 May 22.

Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/ccd.28308DOI Listing
June 2019

p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance.

Oncogene 2019 03 2;38(11):1905-1919. Epub 2018 Nov 2.

Center for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University, Houston, TX, 77030, USA.

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http://www.nature.com/articles/s41388-018-0524-5
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http://dx.doi.org/10.1038/s41388-018-0524-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419514PMC
March 2019

Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma.

Cell Chem Biol 2019 Mar 10;26(3):352-365.e7. Epub 2019 Jan 10.

Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA; Department of Medical Physiology, College of Medicine, Texas A&M University, Temple, TX 76504, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24519456183043
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http://dx.doi.org/10.1016/j.chembiol.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430684PMC
March 2019

Circular RNAs as promising biomarkers in cancer: detection, function, and beyond.

Authors:
Shengli Li Leng Han

Genome Med 2019 03 20;11(1):15. Epub 2019 Mar 20.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.

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https://genomemedicine.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s13073-019-0629-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427893PMC
March 2019

Segmentation of Online Ferrograph Images with Strong Interference Based on Uniform Discrete Curvelet Transformation.

Sensors (Basel) 2019 Mar 30;19(7). Epub 2019 Mar 30.

Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing Systems, Xi'an Jiaotong University, Xi'an 710049, China.

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http://dx.doi.org/10.3390/s19071546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480546PMC
March 2019

A Wear Debris Segmentation Method for Direct Reflection Online Visual Ferrography.

Sensors (Basel) 2019 Feb 11;19(3). Epub 2019 Feb 11.

School of Advanced Manufacture, Chongqing University of Posts and Telecommunications, Chongqing 400065, China.

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http://dx.doi.org/10.3390/s19030723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387466PMC
February 2019

Pancan-meQTL: a database to systematically evaluate the effects of genetic variants on methylation in human cancer.

Nucleic Acids Res 2019 Jan;47(D1):D1066-D1072

Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323988PMC
January 2019

CancerSplicingQTL: a database for genome-wide identification of splicing QTLs in human cancer.

Nucleic Acids Res 2019 Jan;47(D1):D909-D916

Key Laboratory of Environmental Health of Ministry of Education, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324030PMC
January 2019

Lipid storage and lipophagy regulates ferroptosis.

Biochem Biophys Res Commun 2019 01 11;508(4):997-1003. Epub 2018 Dec 11.

Department of Oncology and Hematology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.12.039DOI Listing
January 2019

Intravascular Ultrasound Versus Angiography-Guided Drug-Eluting Stent Implantation: The ULTIMATE Trial.

J Am Coll Cardiol 2018 12 24;72(24):3126-3137. Epub 2018 Sep 24.

Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.09.013DOI Listing
December 2018

Maximizing the Utility of Cancer Transcriptomic Data.

Trends Cancer 2018 12 14;4(12):823-837. Epub 2018 Oct 14.

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Center for Precision Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2018.09.009DOI Listing
December 2018

Global analysis of tRNA and translation factor expression reveals a dynamic landscape of translational regulation in human cancers.

Commun Biol 2018 21;1:234. Epub 2018 Dec 21.

1Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030 USA.

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http://www.nature.com/articles/s42003-018-0239-8
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http://dx.doi.org/10.1038/s42003-018-0239-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303286PMC
December 2018

CircView: a visualization and exploration tool for circular RNAs.

Brief Bioinform 2018 11;19(6):1310-1316

Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School.

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http://dx.doi.org/10.1093/bib/bbx070DOI Listing
November 2018

GSCALite: a web server for gene set cancer analysis.

Bioinformatics 2018 11;34(21):3771-3772

Department of Bioinformatics and Systems Biology, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.

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http://dx.doi.org/10.1093/bioinformatics/bty411DOI Listing
November 2018

TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10.

PLoS Biol 2018 11 8;16(11):e3000051. Epub 2018 Nov 8.

Center for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, Texas, United States of America.

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http://dx.plos.org/10.1371/journal.pbio.3000051
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http://dx.doi.org/10.1371/journal.pbio.3000051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245796PMC
November 2018

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.

Cell Rep 2018 10;25(5):1304-1317.e5

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183156
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http://dx.doi.org/10.1016/j.celrep.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326181PMC
October 2018

Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation.

Biochem Biophys Res Commun 2018 09 23;503(2):856-862. Epub 2018 Jun 23.

Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.06.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095800PMC
September 2018

THO Complex-Dependent Posttranscriptional Control Contributes to Vascular Smooth Muscle Cell Fate Decision.

Circ Res 2018 08;123(5):538-549

From the State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College (X.Y., F.Y., Y.L., F.L., Z.R., B.Z., L.W.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313527DOI Listing
August 2018

The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy.

Cell Syst 2018 Mar 7;6(3):314-328.e2. Epub 2018 Mar 7.

Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center and UTHealth, Houston, TX 77030, USA; Center for Precision Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2018.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056007PMC
March 2018

PancanQTL: systematic identification of cis-eQTLs and trans-eQTLs in 33 cancer types.

Nucleic Acids Res 2018 01;46(D1):D971-D976

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/nar/gkx861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753226PMC
January 2018

CSCD: a database for cancer-specific circular RNAs.

Nucleic Acids Res 2018 01;46(D1):D925-D929

School of Basic Medical Sciences, Wuhan University, Wuhan 430071, Hubei, China.

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http://dx.doi.org/10.1093/nar/gkx863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753219PMC
January 2018

Regulatory RNA Editing Sites in Cancer: Prediction and Beyond.

Authors:
Hang Ruan Leng Han

EBioMedicine 2018 01 16;27:7-8. Epub 2017 Dec 16.

Department of Biochemistry and Molecular Biology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Center for Precision Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828464PMC
January 2018

A Pan-cancer Analysis of the Expression and Clinical Relevance of Small Nucleolar RNAs in Human Cancer.

Cell Rep 2017 Nov;21(7):1968-1981

Department of Biochemistry and Molecular Biology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center UTHealth, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.070DOI Listing
November 2017

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development.

Nat Commun 2017 10 4;8(1):783. Epub 2017 Oct 4.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-017-00902-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627275PMC
October 2017

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover.

RNA 2017 09 30;23(9):1404-1418. Epub 2017 May 30.

Department of Biochemistry and Molecular Biology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA

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http://dx.doi.org/10.1261/rna.061556.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558910PMC
September 2017

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers.

Genome Res 2017 07 14;27(7):1112-1125. Epub 2017 Apr 14.

Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/gr.219741.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495064PMC
July 2017

Recent Advances in High Throughput Sequencing Analysis.

Int J Genomics 2017 19;2017:2454780. Epub 2017 Jun 19.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37027, USA.

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http://dx.doi.org/10.1155/2017/2454780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494582PMC
June 2017

A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

Nat Cell Biol 2017 02 23;19(2):106-119. Epub 2017 Jan 23.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncb3464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336186PMC
February 2017

LNCediting: a database for functional effects of RNA editing in lncRNAs.

Nucleic Acids Res 2017 01 19;45(D1):D79-D84. Epub 2016 Sep 19.

Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA

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http://dx.doi.org/10.1093/nar/gkw835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210611PMC
January 2017

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma.

Genes Dev 2016 06;30(12):1440-53

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA;

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http://dx.doi.org/10.1101/gad.277178.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926866PMC
June 2016

LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress.

Nat Cell Biol 2016 Apr 21;18(4):431-42. Epub 2016 Mar 21.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncb3328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814347PMC
April 2016

RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications.

Authors:
Leng Han Han Liang

Mol Cell Oncol 2016 Mar 14;3(2):e1117702. Epub 2015 Dec 14.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1080/23723556.2015.1117702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905409PMC
March 2016

Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types.

Nat Commun 2014 ;5:3231

1] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms4231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951205PMC
October 2015

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.

Cancer Cell 2015 Oct 1;28(4):515-528. Epub 2015 Oct 1.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108150030
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http://dx.doi.org/10.1016/j.ccell.2015.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605878PMC
October 2015

Advances in computational genomics.

Biomed Res Int 2015 6;2015:187803. Epub 2015 Jan 6.

Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1155/2015/187803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300036PMC
September 2015

TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer.

Cancer Res 2015 Sep 24;75(18):3728-37. Epub 2015 Jul 24.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences, Houston, Texas. Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas.

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http://cancerres.aacrjournals.org/content/75/18/3728.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-15-0273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573884PMC
September 2015

Mining diverse small RNA species in the deep transcriptome.

Trends Biochem Sci 2015 Jan 27;40(1):4-7. Epub 2014 Nov 27.

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09680004140020
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http://dx.doi.org/10.1016/j.tibs.2014.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362530PMC
January 2015

Systematic prioritization and integrative analysis of copy number variations in schizophrenia reveal key schizophrenia susceptibility genes.

Schizophr Bull 2014 Nov 24;40(6):1285-99. Epub 2014 Mar 24.

Flaum Eye Institute and Department of Ophthalmology, University of Rochester, Rochester, NY; College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China;

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http://dx.doi.org/10.1093/schbul/sbu045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193716PMC
November 2014

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

Nat Biotechnol 2014 Jul 22;32(7):644-52. Epub 2014 Jun 22.

1] Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USA. [2] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. [3].

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http://www.nature.com/articles/nbt.2940
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http://dx.doi.org/10.1038/nbt.2940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102885PMC
July 2014

The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes.

Nat Commun 2014 Jul 7;5:3963. Epub 2014 Jul 7.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX 77030, USA.

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http://www.nature.com/articles/ncomms4963
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http://dx.doi.org/10.1038/ncomms4963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339277PMC
July 2014

INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development.

Cell Stem Cell 2014 May;14(5):575-91

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154226PMC
May 2014

Finding the lost treasures in exome sequencing data.

Trends Genet 2013 Oct 22;29(10):593-9. Epub 2013 Aug 22.

Center for Human Genetics Research, Vanderbilt University, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1016/j.tig.2013.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926691PMC
October 2013

Investigating the relationship of DNA methylation with mutation rate and allele frequency in the human genome.

BMC Genomics 2012 17;13 Suppl 8:S7. Epub 2012 Dec 17.

Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1186/1471-2164-13-S8-S7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535710PMC
June 2013

Analysis of a new type of major ampullate spider silk gene, MaSp1s.

Int J Biol Macromol 2013 May 8;56:156-61. Epub 2013 Feb 8.

Division of Applied Biology, Faculty of Textile Science and Technology, Shinshu University, Ueda, Nagano 386-8567, Japan.

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http://dx.doi.org/10.1016/j.ijbiomac.2013.01.034DOI Listing
May 2013

Dissecting the molecular relationship among various cardiogenic progenitor cells.

Circ Res 2013 Apr 5;112(9):1253-62. Epub 2013 Mar 5.

Division of Cardiology, Department of Medicine, Stanford Cardiovascular Institute, Institute of Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305-5454, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.112.300779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657513PMC
April 2013

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

Stem Cells 2013 Feb;31(2):259-68

Department of Medicine, Division of Cardiology, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1002/stem.1278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572288PMC
February 2013

Features of methylation and gene expression in the promoter-associated CpG islands using human methylome data.

Comp Funct Genomics 2012 4;2012:598987. Epub 2012 Mar 4.

College of Life Sciences, Central China Normal University, Wuhan 430079, China.

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http://dx.doi.org/10.1155/2012/598987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303704PMC
August 2012

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes.

Epigenetics 2011 Feb 1;6(2):134-40. Epub 2011 Feb 1.

Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278781PMC
http://dx.doi.org/10.4161/epi.6.2.13875DOI Listing
February 2011

Gene- and evidence-based candidate gene selection for schizophrenia and gene feature analysis.

Artif Intell Med 2010 Feb-Mar;48(2-3):99-106. Epub 2009 Nov 26.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S093336570900102
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http://dx.doi.org/10.1016/j.artmed.2009.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826526PMC
May 2010