Lene Christiansen

Lene Christiansen

UNVERIFIED PROFILE

Are you Lene Christiansen?   Register this Author

Register author
Lene Christiansen

Lene Christiansen

Publications by authors named "Lene Christiansen"

Are you Lene Christiansen?   Register this Author

100Publications

2625Reads

40Profile Views

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 Aug 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Epigenetic signature of preterm birth in adult twins.

Clin Epigenetics 2018 27;10:87. Epub 2018 Jun 27.

1Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000 Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-018-0518-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020425PMC
July 2019

Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Biogerontology 2019 Jun 28. Epub 2019 Jun 28.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9B, 5000, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10522-019-09818-1DOI Listing
June 2019

DNA methylome profiling in identical twin pairs discordant for body mass index.

Int J Obes (Lond) 2019 May 31. Epub 2019 May 31.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41366-019-0382-4DOI Listing
May 2019

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies.

J Gerontol A Biol Sci Med Sci 2019 Mar 15. Epub 2019 Mar 15.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology and Biostatistics Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
https://academic.oup.com/biomedgerontology/advance-article/d
Publisher Site
http://dx.doi.org/10.1093/gerona/glz070DOI Listing
March 2019

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns.

Clin Epigenetics 2019 02 8;11(1):23. Epub 2019 Feb 8.

Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-019-0622-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368749PMC
February 2019

White blood cell mitochondrial DNA copy number is decreased in rheumatoid arthritis and linked with risk factors. A twin study.

J Autoimmun 2019 Jan 14;96:142-146. Epub 2018 Oct 14.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2018.09.008DOI Listing
January 2019

On the power of epigenome-wide association studies using a disease-discordant twin design.

Bioinformatics 2018 12;34(23):4073-4078

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bty532DOI Listing
December 2018

Lung function discordance in monozygotic twins and associated differences in blood DNA methylation.

Clin Epigenetics 2017 21;9:132. Epub 2017 Dec 21.

Department of Public Health, Section for Environment Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-017-0427-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740718PMC
September 2018

Circulating microRNAs disclose biology of normal cognitive function in healthy elderly people - a discovery twin study.

Eur J Hum Genet 2018 09 2;26(9):1378-1387. Epub 2018 May 2.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology, Biostatistics and Biodemography Unit, Department of Public Health, University of Southern Denmark, 5000, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41431-018-0157-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117263PMC
September 2018

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.

Aging Cell 2018 06 25;17(3):e12755. Epub 2018 Mar 25.

Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073PMC
June 2018

Genetic and environmental influences on cardiovascular risk factors and cognitive function: A Chinese twin aging study.

Geriatr Gerontol Int 2018 Feb 30;18(2):352-359. Epub 2017 Aug 30.

Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ggi.13161DOI Listing
February 2018

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins.

Genes (Basel) 2018 Feb 8;9(2). Epub 2018 Feb 8.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, 5000 Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/genes9020078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852574PMC
February 2018

DNA methylation age and perceived age in elderly Danish twins.

Mech Ageing Dev 2018 01 28;169:40-44. Epub 2017 Sep 28.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; The Danish Twin Registry and the Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mad.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190692PMC
January 2018

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins.

Front Aging Neurosci 2017 12;9:413. Epub 2017 Dec 12.

The Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnagi.2017.00413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733014PMC
December 2017

Handling blood cell composition in epigenetic studies on ageing.

Int J Epidemiol 2017 10;46(5):1717-1718

Department of Public Health.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyx083DOI Listing
October 2017

Untargeted GC-MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth.

Biotechnol J 2017 Oct 16;12(10). Epub 2017 Oct 16.

Faculty of Science, Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/biot.201700400DOI Listing
October 2017

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis.

Sci Rep 2017 08 15;7(1):8183. Epub 2017 Aug 15.

Department of Clinical Research, Unit of Human Genetics, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-08346-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557932PMC
August 2017

Investigation of the 5q33.3 longevity locus and age-related phenotypes.

Aging (Albany NY) 2017 01;9(1):247-255

The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5000 Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310666PMC
January 2017

Genetic Influence on the Peripheral Blood CD4+ T-cell Differentiation Status in CMV Infection.

J Gerontol A Biol Sci Med Sci 2016 12 11;71(12):1537-1543. Epub 2016 Jan 11.

Second Department of Internal Medicine, Center for Medical Research, University of Tübingen Medical School, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/glv230DOI Listing
December 2016

Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots.

Clin Epigenetics 2016 26;8:81. Epub 2016 Jul 26.

Translational Neuropsychiatric Unit, Aarhus University Hospital, Risskov, 8240 Denmark ; Research Department P, Aarhus University Hospital, Risskov, 8240 Denmark ; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-016-0242-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960904PMC
December 2016

Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study.

Front Immunol 2016 17;7:510. Epub 2016 Nov 17.

The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark; Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2016.00510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112246PMC
November 2016

Somatically acquired structural genetic differences: a longitudinal study of elderly Danish twins.

Eur J Hum Genet 2016 10 20;24(10):1506-10. Epub 2016 Apr 20.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2016.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027681PMC
October 2016

Genetic Variants in KLOTHO Associate With Cognitive Function in the Oldest Old Group.

J Gerontol A Biol Sci Med Sci 2016 09 24;71(9):1151-9. Epub 2015 Sep 24.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology, Biostatistics and Biodemography Unit, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/glv163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978356PMC
September 2016

Epigenetic drift in the aging genome: a ten-year follow-up in an elderly twin cohort.

Int J Epidemiol 2016 08 6;45(4):1146-1158. Epub 2016 Aug 6.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyw132DOI Listing
August 2016

No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.

Exp Gerontol 2016 Jun 3;78:57-61. Epub 2016 Mar 3.

Epidemiology, Biostatistics and Biodemography, The Danish Aging Research Center, Department of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000 Odense C, Denmark. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709PMC
June 2016

Danish cohort of monozygotic inflammatory bowel disease twins: Clinical characteristics and inflammatory activity.

World J Gastroenterol 2016 Jun;22(21):5050-9

Frederik Trier Moller, Lina Knudsen, Vibeke Andersen, Research Unit for Molecular Diagnostics, Hospital of Southern Jutland, 6200 Aabenraa, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v22.i21.5050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886380PMC
June 2016

Change in Depression Symptomatology and Cognitive Function in Twins: A 10-Year Follow-Up Study.

Twin Res Hum Genet 2016 Apr 16;19(2):104-11. Epub 2016 Feb 16.

The Danish Twin Registry,Unit of Epidemiology,Biostatistics and Biodemography,Institute of Public Health,University of Southern Denmark,Odense,Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/thg.2016.3DOI Listing
April 2016

Differentially Methylated Genomic Regions in Birth-Weight Discordant Twin Pairs.

Ann Hum Genet 2016 Mar 1;80(2):81-7. Epub 2016 Feb 1.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ahg.12146DOI Listing
March 2016

Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment.

Aging Cell 2016 Feb 8;15(1):49-55. Epub 2015 Oct 8.

The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717275PMC
February 2016

DNA methylation age is associated with mortality in a longitudinal Danish twin study.

Aging Cell 2016 Feb 17;15(1):149-54. Epub 2015 Nov 17.

The Danish Aging Research Center, and The Danish twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717264PMC
February 2016

The APP A673T frequency differs between Nordic countries.

Neurobiol Aging 2015 Oct 11;36(10):2909.e1-4. Epub 2015 Jul 11.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology, Biostatistics and Biodemography Unit, Department of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2015.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562869PMC
October 2015

A twin study of the trough plasma steady-state concentration of metformin.

Pharmacogenet Genomics 2015 May;25(5):259-62

aClinical Pharmacology, Department of Public Health, University of Southern Denmark bEpidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark cDepartment of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0000000000000133DOI Listing
May 2015

Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals.

Aging Cell 2015 Feb 2;14(1):60-6. Epub 2014 Dec 2.

The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000, Odense C, Denmark; Department of Clinical Genetics, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326903PMC
February 2015

Twin methodology in epigenetic studies.

J Exp Biol 2015 Jan;218(Pt 1):134-9

Epidemiology, Biostatistics and Bio-demography, Institute of Public Health, University of Southern Denmark, DK-5000, Odense C, Denmark Human Genetics, Institute of Clinical Research, University of Southern Denmark, DK-5000, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jeb.107151DOI Listing
January 2015

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.

Authors:
Qibin Qi Tuomas O Kilpeläinen Mary K Downer Toshiko Tanaka Caren E Smith Ivonne Sluijs Emily Sonestedt Audrey Y Chu Frida Renström Xiaochen Lin Lars H Ängquist Jinyan Huang Zhonghua Liu Yanping Li Muhammad Asif Ali Min Xu Tarunveer Singh Ahluwalia Jolanda M A Boer Peng Chen Makoto Daimon Johan Eriksson Markus Perola Yechiel Friedlander Yu-Tang Gao Denise H M Heppe John W Holloway Denise K Houston Stavroula Kanoni Yu-Mi Kim Maarit A Laaksonen Tiina Jääskeläinen Nanette R Lee Terho Lehtimäki Rozenn N Lemaitre Wei Lu Robert N Luben Ani Manichaikul Satu Männistö Pedro Marques-Vidal Keri L Monda Julius S Ngwa Louis Perusse Frank J A van Rooij Yong-Bing Xiang Wanqing Wen Mary K Wojczynski Jingwen Zhu Ingrid B Borecki Claude Bouchard Qiuyin Cai Cyrus Cooper George V Dedoussis Panos Deloukas Luigi Ferrucci Nita G Forouhi Torben Hansen Lene Christiansen Albert Hofman Ingegerd Johansson Torben Jørgensen Shigeru Karasawa Kay-Tee Khaw Mi-Kyung Kim Kati Kristiansson Huaixing Li Xu Lin Yongmei Liu Kurt K Lohman Jirong Long Vera Mikkilä Dariush Mozaffarian Kari North Oluf Pedersen Olli Raitakari Harri Rissanen Jaakko Tuomilehto Yvonne T van der Schouw André G Uitterlinden M Carola Zillikens Oscar H Franco E Shyong Tai Xiao Ou Shu David S Siscovick Ulla Toft W M Monique Verschuren Peter Vollenweider Nicholas J Wareham Jacqueline C M Witteman Wei Zheng Paul M Ridker Jae H Kang Liming Liang Majken K Jensen Gary C Curhan Louis R Pasquale David J Hunter Karen L Mohlke Matti Uusitupa L Adrienne Cupples Tuomo Rankinen Marju Orho-Melander Tao Wang Daniel I Chasman Paul W Franks Thorkild I A Sørensen Frank B Hu Ruth J F Loos Jennifer A Nettleton Lu Qi

Hum Mol Genet 2014 Dec 7;23(25):6961-72. Epub 2014 Aug 7.

Department of Nutrition and Channing Division of Network Medicine, Department of Medicine

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddu411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271061PMC
December 2014

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers.

PLoS Genet 2014 Dec 4;10(12):e1004799. Epub 2014 Dec 4.

BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256159PMC
December 2014

Epigenetic signature of birth weight discordance in adult twins.

BMC Genomics 2014 Dec 4;15:1062. Epub 2014 Dec 4.

Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, J, B, Winsløws Vej 9B, DK-5000 Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-15-1062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302120PMC
December 2014

Hierarchical linear modeling of longitudinal pedigree data for genetic association analysis.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S82. Epub 2014 Jun 17.

Institute of Clinical Research, Unit of Human Genetics, University of Southern Denmark, Sdr. Boulevard 29, 5000 Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1753-6561-8-S1-S82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144324PMC
December 2014

[The genome and ageing].

Ugeskr Laeger 2014 Nov;176(46)

Dansk Center for Aldringsforskning, Institut for Sundhedstjenesteforskning, Syddansk Universitet, J.B. Winsløwsvej 9B, 5000 Odense.

View Article

Download full-text PDF

Source
November 2014

Genetic variants associated with lung function: the long life family study.

Respir Res 2014 Nov 1;15:134. Epub 2014 Nov 1.

Department of Laboratory Medicine and Pathology, University of Minnesota, 515 Delaware Street SE, 1-136 Moos Towers, Minneapolis 55455, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12931-014-0134-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228089PMC
November 2014

Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.

Eur J Hum Genet 2014 Sep 12;22(9):1131-6. Epub 2014 Feb 12.

1] Epidemiology, Biostatistics and Biodemography, The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense, Denmark [2] Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.

View Article

Download full-text PDF

Source
http://www.ideal-ageing.eu/uploads/publicaties/2014/2014_deb
Web Search
http://www.nature.com/doifinder/10.1038/ejhg.2013.299
Publisher Site
http://dx.doi.org/10.1038/ejhg.2013.299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135411PMC
September 2014

Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals.

Exp Gerontol 2014 Sep 5;57:41-6. Epub 2014 May 5.

The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000 Odense C, Denmark; Department of Clinical Genetics, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark; Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2014.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149928PMC
September 2014

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly.

Hum Genet 2014 Sep 6;133(9):1149-59. Epub 2014 Jun 6.

Epidemiology, Biostatistics and Biodemography Unit, The Danish Aging Research Center, The Danish Twin Registry, Institute of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9, 5000, Odense, Denmark,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-014-1458-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127366PMC
September 2014

CLU genetic variants and cognitive decline among elderly and oldest old.

PLoS One 2013 14;8(11):e79105. Epub 2013 Nov 14.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark ; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079105PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828341PMC
August 2014

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum Mol Genet 2014 Aug 31;23(16):4420-32. Epub 2014 Mar 31.

Department of Molecular Epidemiology, Netherlands Consortium for Healthy Ageing,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddu139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103672PMC
August 2014

Birth weight and adult bone metabolism are unrelated: results from birth weight-discordant monozygotic twins.

J Bone Miner Res 2013 Dec;28(12):2561-9

The Danish Twin Registry, Danish Ageing Research Centre, University of Southern Denmark, Odense, Denmark; Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark.

View Article

Download full-text PDF

Source
http://www.ideal-ageing.eu/uploads/publicaties/2013_frost_jb
Web Search
http://doi.wiley.com/10.1002/jbmr.1995
Publisher Site
http://dx.doi.org/10.1002/jbmr.1995DOI Listing
December 2013

Personality factors in the Long Life Family Study.

J Gerontol B Psychol Sci Soc Sci 2013 Sep 28;68(5):739-49. Epub 2012 Dec 28.

New England Centenarian Study, Robinson 2400, 88 E Newton St, Boston, MA 02118, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/psychsocgerontology/article-lookup/
Publisher Site
http://dx.doi.org/10.1093/geronb/gbs117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744045PMC
September 2013

A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family.

Aging Cell 2013 Aug 15;12(4):690-4. Epub 2013 May 15.

Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714332PMC
August 2013

Analyzing age-specific genetic effects on human extreme age survival in cohort-based longitudinal studies.

Eur J Hum Genet 2013 Apr 15;21(4):451-4. Epub 2012 Aug 15.

Institute of Public Health, University of Southern Denmark, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2012.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598313PMC
April 2013

Effects of the APOE ε2 allele on mortality and cognitive function in the oldest old.

J Gerontol A Biol Sci Med Sci 2013 Apr 9;68(4):389-94. Epub 2012 Oct 9.

Danish Aging Research Center, Epidemiology, University of Southern Denmark, J.B. Winsløws Vej 9B, DK-5000 Odense C, Denmark.

View Article

Download full-text PDF

Source
https://academic.oup.com/biomedgerontology/article-lookup/do
Publisher Site
http://dx.doi.org/10.1093/gerona/gls192DOI Listing
April 2013

Twins for epigenetic studies of human aging and development.

Ageing Res Rev 2013 Jan 29;12(1):182-7. Epub 2012 Jun 29.

The Danish Twin Registry and The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2012.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509237PMC
January 2013

UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts.

Mech Ageing Dev 2012 Aug 26;133(8):530-7. Epub 2012 Jun 26.

Department of Cell Biology, University of Calabria, Ponte Pietro Bucci cubo 4C, 87036 Rende (CS), Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mad.2012.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629378PMC
August 2012

Skewed X inactivation and survival: a 13-year follow-up study of elderly twins and singletons.

Eur J Hum Genet 2012 Mar 7;20(3):361-4. Epub 2011 Dec 7.

Epidemiology Unit, The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2011.215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283187PMC
March 2012

Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.

Neurobiol Aging 2011 Mar 23;32(3):554.e7-11. Epub 2010 Aug 23.

The Danish Aging Research Center, Epidemiology Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2010.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042035PMC
March 2011

Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies.

Aging Cell 2010 Dec 21;9(6):1004-9. Epub 2010 Oct 21.

Danish Aging Research Center, Epidemiology, University of Southern Denmark, JB Winsløws Vej 9B, DK-5000 Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1474-9726.2010.00626.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988163PMC
December 2010

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data.

Aging Cell 2010 Dec 21;9(6):1010-7. Epub 2010 Oct 21.

The Danish Aging Research Center, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1474-9726.2010.00627.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992870PMC
December 2010