Lena-Christin Conradi

Lena-Christin Conradi

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Lena-Christin Conradi

Lena-Christin Conradi

Publications by authors named "Lena-Christin Conradi"

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36Publications

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Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer.

BMC Cancer 2019 Sep 5;19(1):880. Epub 2019 Sep 5.

Department of General, Visceral and Pediatric Surgery, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075, Goettingen, Germany.

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http://dx.doi.org/10.1186/s12885-019-6051-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727342PMC
September 2019

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

Cell Metab 2018 12 23;28(6):866-880.e15. Epub 2018 Aug 23.

Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183046
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http://dx.doi.org/10.1016/j.cmet.2018.07.019DOI Listing
December 2018

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.

Cell Metab 2018 12 23;28(6):881-894.e13. Epub 2018 Aug 23.

Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 51006, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.07.016DOI Listing
December 2018

Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion.

Cancer Cell 2018 08;34(2):298-314.e7

Institute of Molecular Oncology, University Medical Center Göttingen, Göttingen 37077, Germany; Department of Pathology, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582949PMC
August 2018

Tumor vessel disintegration by maximum tolerable PFKFB3 blockade.

Angiogenesis 2017 Nov 5;20(4):599-613. Epub 2017 Sep 5.

Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s10456-017-9573-6DOI Listing
November 2017

The utilization of multidisciplinary tumor boards (MDT) in clinical routine: results of a health care research study focusing on patients with metastasized colorectal cancer.

Int J Colorectal Dis 2017 Oct 5;32(10):1463-1469. Epub 2017 Aug 5.

Department of General, Visceral and Pediatric Surgery, University Medical Center Georg-August-University, Robert-Koch-Strasse 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1007/s00384-017-2871-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596058PMC
October 2017

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease.

Physiology (Bethesda) 2017 03;32(2):126-140

Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, Leuven, Belgium; and

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http://dx.doi.org/10.1152/physiol.00031.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337830PMC
March 2017

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities.

EMBO Mol Med 2016 10 4;8(10):1134-1142. Epub 2016 Oct 4.

Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, VIB, Leuven, Belgium

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http://dx.doi.org/10.15252/emmm.201606798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048364PMC
October 2016

Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers-A New Perspective?

Pharmacol Rev 2016 07;68(3):872-87

Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, University of Leuven, and Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, Leuven, Belgium

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http://dx.doi.org/10.1124/pr.116.012492DOI Listing
July 2016

Glycolytic regulation of cell rearrangement in angiogenesis.

Nat Commun 2016 07 20;7:12240. Epub 2016 Jul 20.

Department of Oncology, Laboratory of Angiogenesis and Vascular Metabolism, KU Leuven, Herestraat 49 box 912, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1038/ncomms12240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961802PMC
July 2016

Stage-Dependent Frequency of Lymph Node Metastases in Patients With Rectal Carcinoma After Preoperative Chemoradiation: Results from the CAO/ARO/AIO-94 Trial and From a Comparative Prospective Evaluation With Extensive Pathological Workup.

Dis Colon Rectum 2016 May;59(5):377-85

1 Department of General, Visceral and Pediatric Surgery, University Medical Center Goettingen, Goettingen, Germany 2 Department of Pathology, Medical Care Unit Goettingen, Goettingen, Germany 3 Department of Medical Statistics, University Medical Center Goettingen, Goettingen, Germany 4 Department of Pathology, University Medical Center Goettingen, Goettingen, Germany 5 Department of Radiotherapy and Radiooncology, University Medical Center Goettingen, Goettingen, Germany 6 Institute of Pathology, University Hospital Leipzig, Leipzig, Germany 7 Department of Radiation Therapy, University of Erlangen, Erlangen, Germany 8 Department of Radiotherapy and Oncology, University of Frankfurt, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1097/DCR.0000000000000570DOI Listing
May 2016

STED super-resolution microscopy of clinical paraffin-embedded human rectal cancer tissue.

PLoS One 2014 15;9(7):e101563. Epub 2014 Jul 15.

Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany; Department of Neurology, University Medical Center of Göttingen, Göttingen, Germany; Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101563PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099123PMC
March 2015

Gender-specific acute organ toxicity during intensified preoperative radiochemotherapy for rectal cancer.

Oncologist 2011 9;16(5):621-31. Epub 2011 May 9.

Department of Radiotherapy and Radiooncology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1634/theoncologist.2010-0414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228181PMC
September 2011