Lena Smirnova

Lena Smirnova

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Lena Smirnova

Lena Smirnova

Publications by authors named "Lena Smirnova"

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Corrigendum to Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity Toxicol Appl Pharmacol, 354 (2018) 64-80.

Toxicol Appl Pharmacol 2019 Jun 16;372:70. Epub 2019 Apr 16.

In Vitro Toxicology and Biomedicine, Dept Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457 Konstanz, Germany; CAAT-Europe, University of Konstanz, Konstanz 78457, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.04.010DOI Listing
June 2019

Animal testing and its alternatives - the most important omics is economics.

ALTEX 2018 ;35(3):275-305

Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.14573/altex.1807041DOI Listing
November 2018

3S - Systematic, systemic, and systems biology and toxicology.

ALTEX 2018 ;35(2):139-162

Johns Hopkins University, Bloomberg School of Public Health, Center for Alternatives to Animal Testing (CAAT), Baltimore, MD, USA.

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http://dx.doi.org/10.14573/altex.1804051DOI Listing
October 2018

Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity.

Toxicol Appl Pharmacol 2018 09 24;354:64-80. Epub 2017 Dec 24.

In Vitro Toxicology and Biomedicine, Dept Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457 Konstanz, Germany; CAAT-Europe, University of Konstanz, Konstanz 78457, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2017.12.013DOI Listing
September 2018

Rotenone exerts developmental neurotoxicity in a human brain spheroid model.

Toxicol Appl Pharmacol 2018 09 8;354:101-114. Epub 2018 Feb 8.

Center for Alternative to Animal Testing (CAAT), Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2018.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082736PMC
September 2018

3D Differentiation of LUHMES Cell Line to Study Recovery and Delayed Neurotoxic Effects.

Curr Protoc Toxicol 2017 Aug 4;73:11.23.1-11.23.28. Epub 2017 Aug 4.

Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1002/cptx.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674809PMC
August 2017

Characterization of three human cell line models for high-throughput neuronal cytotoxicity screening.

J Appl Toxicol 2017 02 3;37(2):167-180. Epub 2016 May 3.

National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Rockville, MD, USA.

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http://doi.wiley.com/10.1002/jat.3334
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http://dx.doi.org/10.1002/jat.3334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094908PMC
February 2017

Cellular resilience.

ALTEX 2015 ;32(4):247-60

Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA;

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http://dx.doi.org/10.14573/altex.1509271DOI Listing
June 2016

microRNA Profiling as Tool for Developmental Neurotoxicity Testing (DNT).

Curr Protoc Toxicol 2015 May 4;64:20.9.1-22. Epub 2015 May 4.

Department of Chemicals and Products Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.

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http://dx.doi.org/10.1002/0471140856.tx2009s64DOI Listing
May 2015

On the role of low-dose effects and epigenetics in toxicology.

Exp Suppl 2012;101:499-550

Department of Product Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.

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http://dx.doi.org/10.1007/978-3-7643-8340-4_18DOI Listing
March 2015

Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.

ALTEX 2014 ;31(2):129-56

Centers for Alternatives to Animal Testing (CAAT) at Johns Hopkins Bloomberg School of Public Health, USA.

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http://dx.doi.org/10.14573/altex.1403271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778747PMC
January 2015

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.

Nat Cell Biol 2009 Dec 8;11(12):1411-20. Epub 2009 Nov 8.

Center for Anatomy, Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1038/ncb1987DOI Listing
December 2009

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.

Nat Cell Biol 2008 Aug 6;10(8):987-93. Epub 2008 Jul 6.

Institute of Cell and Neurobiology, Center for Anatomy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1038/ncb1759DOI Listing
August 2008

Cancer-associated alteration in fatty acid binding to albumin studied by spin-label electron spin resonance.

Cancer Invest 2007 Sep;25(6):378-83

Department of Research and Development, MedInnovation GmbH, Berlin, Germany.

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http://dx.doi.org/10.1080/07357900701407947DOI Listing
September 2007

Post-transcriptional regulation of the let-7 microRNA during neural cell specification.

FASEB J 2007 Feb 13;21(2):415-26. Epub 2006 Dec 13.

Center for Anatomy, Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, Schumannstrasse 20-21, 10098 Berlin, Germany.

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http://www.fasebj.org/doi/10.1096/fj.06-6130com
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http://dx.doi.org/10.1096/fj.06-6130comDOI Listing
February 2007

Regulation of miRNA expression during neural cell specification.

Eur J Neurosci 2005 Mar;21(6):1469-77

Center for Anatomy, Institute of Cell Biology and Neurobiology, Charité University Hospital, Schumannstrasse 20-21, 10098 Berlin, Germany.

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http://doi.wiley.com/10.1111/j.1460-9568.2005.03978.x
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http://dx.doi.org/10.1111/j.1460-9568.2005.03978.xDOI Listing
March 2005