Leigh Goedeke

Leigh Goedeke

UNVERIFIED PROFILE

Are you Leigh Goedeke?   Register this Author

Register author
Leigh Goedeke

Leigh Goedeke

Publications by authors named "Leigh Goedeke"

Are you Leigh Goedeke?   Register this Author

30Publications

867Reads

34Profile Views

Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes.

Annu Rev Pharmacol Toxicol 2019 01;59:65-87

Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA; email: , ,

View Article

Download full-text PDF

Source
https://www.annualreviews.org/doi/10.1146/annurev-pharmtox-0
Publisher Site
http://dx.doi.org/10.1146/annurev-pharmtox-010716-104727DOI Listing
January 2019

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance.

Cell Rep 2018 02;22(8):2133-2145

Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.01.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860817PMC
February 2018

miRNA regulation of LDL-cholesterol metabolism.

Biochim Biophys Acta 2016 12 9;1861(12 Pt B):2047-2052. Epub 2016 Mar 9.

Massachusetts General Hospital Center for Cancer Research, Charlestown, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2016.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375104PMC
December 2016

Micro-RNAs and High-Density Lipoprotein Metabolism.

Arterioscler Thromb Vasc Biol 2016 06 14;36(6):1076-84. Epub 2016 Apr 14.

From the Vascular Biology and Therapeutics Program (A.C.-D., L.G., Y.S., C.F.-H.) and Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine and Department of Pathology (A.C.-D., L.G., Y.S., C.F.-H.), Yale University School of Medicine, New Haven, CT; and Division of Cardiology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan (C.-S.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.116.307028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315356PMC
June 2016

microRNAs in lipoprotein metabolism and cardiometabolic disorders.

Atherosclerosis 2016 Mar 18;246:352-60. Epub 2016 Jan 18.

Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine and Department of Pathology, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2016.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357236PMC
March 2016

miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice.

Atherosclerosis 2015 Dec;243(2):499-509

Section of Comparative Medicine, Department of Pathology, Program in Integrative Cell Signaling and Neurobiology of Metabolism and the Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, 06520, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2015.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975922PMC
December 2015

The miR-199-dynamin regulatory axis controls receptor-mediated endocytosis.

J Cell Sci 2015 Sep 10;128(17):3197-209. Epub 2015 Jul 10.

Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06510, USA Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06510, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.165233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582188PMC
September 2015

Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis.

FASEB J 2015 Feb 12;29(2):597-610. Epub 2014 Nov 12.

*Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, USA; Departments of Medicine, Leon H. Charney Division of Cardiology, and Cell Biology, New York University School of Medicine, New York, New York, USA; and Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.14-262097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314230PMC
February 2015

MicroRNAs: a connection between cholesterol metabolism and neurodegeneration.

Neurobiol Dis 2014 Dec 5;72 Pt A:48-53. Epub 2014 Jun 5.

Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2014.05.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252369PMC
December 2014

Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice.

EMBO Mol Med 2014 Sep;6(9):1133-41

Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine Yale University School of Medicine, New Haven, CT, USA Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, NY, USA Marc and Ruti Bell Vascular Biology and Disease Program, New York University School of Medicine, New York, NY, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/emmm.201404046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197861PMC
September 2014

microRNAs and HDL life cycle.

Cardiovasc Res 2014 Aug 3;103(3):414-22. Epub 2014 Jun 3.

Vascular Biology and Therapeutics Program, Yale University School of Medicine, 10 Amistad Street, Amistad Research Building, Room 337C, New Haven 06510, CT, USA Integrative Cell Signalling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cvr/cvu140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176044PMC
August 2014

microRNA regulation of lipoprotein metabolism.

Curr Opin Lipidol 2014 Aug;25(4):282-8

aVascular Biology and Therapeutics Program bIntegrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut cDepartment of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOL.0000000000000094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315358PMC
August 2014

RNA binding protein HuR regulates the expression of ABCA1.

J Lipid Res 2014 06 11;55(6):1066-76. Epub 2014 Apr 11.

Vascular Biology and Therapeutics Program, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520 Departments of Medicine and Cell Biology, New York University School of Medicine, New York, NY 10016.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M044925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031938PMC
June 2014

MicroRNA 33 regulates glucose metabolism.

Mol Cell Biol 2013 Aug 28;33(15):2891-902. Epub 2013 May 28.

Department of Medicine, Leon H. Charney Division of Cardiology and Marc and Ruti Bell Vascular Biology and Disease Program, New York University School of Medicine, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00016-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719675PMC
August 2013

MicroRNAs in metabolic disease.

Arterioscler Thromb Vasc Biol 2013 Feb;33(2):178-85

Departments of Medicine and Cell Biology, Leon H. Charney Division of Cardiology and the Marc and Ruti Bell Vascular Biology and Disease Program, New York University School of Medicine, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.112.300144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740757PMC
February 2013

Regulation of cholesterol homeostasis.

Cell Mol Life Sci 2012 Mar 19;69(6):915-30. Epub 2011 Oct 19.

Departments of Medicine and Cell Biology, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY 10016, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-011-0857-5DOI Listing
March 2012

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1.

Arterioscler Thromb Vasc Biol 2011 Nov;31(11):2707-14

Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.111.232066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298756PMC
November 2011

"Micromanaging" metabolic syndrome.

Cell Cycle 2011 Oct 1;10(19):3249-52. Epub 2011 Oct 1.

Department of Medicine, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.10.19.17558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233620PMC
October 2011

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.

Nature 2011 Oct 19;478(7369):404-7. Epub 2011 Oct 19.

Marc and Ruti Bell Vascular Biology and Disease Program, Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, New York 10016, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature10486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235584PMC
October 2011