Leigh Carmody

Leigh Carmody

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Leigh Carmody

Leigh Carmody

Publications by authors named "Leigh Carmody"

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17Publications

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Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.

Nucleic Acids Res 2019 Jan;47(D1):D1018-D1027

Monarch Initiative, monarchinitiative.org.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky1105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324074PMC
January 2019

Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.

Bioorg Med Chem Lett 2013 Mar 16;23(6):1834-8. Epub 2013 Jan 16.

Chemical Biology Platform and Probe Development Center, Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.01.025DOI Listing
March 2013

Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation.

J Biomol Screen 2012 Oct 1;17(9):1221-30. Epub 2012 Aug 1.

Department of Pathology and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1177/1087057112455060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097195PMC
October 2012

Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells.

J Biomol Screen 2012 Oct 30;17(9):1204-10. Epub 2012 Aug 30.

Chemical Biology Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1177/1087057112458317DOI Listing
October 2012

Identification of a selective small molecule inhibitor of breast cancer stem cells.

Bioorg Med Chem Lett 2012 May 25;22(10):3571-4. Epub 2012 Jan 25.

Chemical Biology Platform and Probe Development Center, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.bmcl.2012.01.035DOI Listing
May 2012

Identification of small-molecule inhibitors of Trypansoma cruzi replication.

Bioorg Med Chem Lett 2011 Dec 29;21(23):7197-200. Epub 2011 Sep 29.

Chemical Biology Platform and Probe Development Center, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.bmcl.2011.09.057DOI Listing
December 2011

Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin.

FASEB J 2008 Jun 23;22(6):1660-71. Epub 2008 Jan 23.

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1096/fj.07-092841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814319PMC
June 2008

Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2.

J Biol Chem 2005 Oct 24;280(42):35329-36. Epub 2005 Aug 24.

Department of Molecular Physiology and Biophysics, Center for Molecular Neuroscience, Vanderbilt-Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, Tennessee 37232-0615, USA.

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http://dx.doi.org/10.1074/jbc.M502191200DOI Listing
October 2005

A protein phosphatase-1gamma1 isoform selectivity determinant in dendritic spine-associated neurabin.

J Biol Chem 2004 May 11;279(21):21714-23. Epub 2004 Mar 11.

Department of Molecular Physiology and Biophysics, The Center for Molecular Neuroscience, and The Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0615, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M402261200
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http://dx.doi.org/10.1074/jbc.M402261200DOI Listing
May 2004

Analysis of specific interactions of native protein phosphatase 1 isoforms with targeting subunits.

Methods Enzymol 2003 ;366:156-75

Room 702, Light Hall, Vanderbilt University Medical Center, Nashville, Tennessee 37232-0615, USA.

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http://dx.doi.org/10.1016/s0076-6879(03)66014-3DOI Listing
January 2004

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.

J Biol Chem 2002 Aug 16;277(31):27716-24. Epub 2002 May 16.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M203365200DOI Listing
August 2002