Publications by authors named "Lehn K Weaver"

16Publications

Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.

JCI Insight 2019 03 7;5. Epub 2019 Mar 7.

Department of Medicine, Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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March 2019

Microbiota-dependent signals are required to sustain TLR-mediated immune responses.

JCI Insight 2019 Jan 10;4(1). Epub 2019 Jan 10.

Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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January 2019

Brief Report: Interferon-γ-Mediated Immunopathology Potentiated by Toll-Like Receptor 9 Activation in a Murine Model of Macrophage Activation Syndrome.

Arthritis Rheumatol 2019 01 24;71(1):161-168. Epub 2018 Nov 24.

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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January 2019

Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis.

Curr Treatm Opt Rheumatol 2017 Mar 7;3(1):33-48. Epub 2017 Feb 7.

Division of Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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March 2017

IL-10 distinguishes a unique population of activated, effector-like CD8 T cells in murine acute liver inflammation.

J Leukoc Biol 2017 04 29;101(4):1037-1044. Epub 2016 Dec 29.

Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA;

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April 2017

TLR9-mediated inflammation drives a Ccr2-independent peripheral monocytosis through enhanced extramedullary monocytopoiesis.

Proc Natl Acad Sci U S A 2016 09 12;113(39):10944-9. Epub 2016 Sep 12.

Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA 19104

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September 2016

Dissecting the heterogeneity of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

J Rheumatol 2015 Jun 15;42(6):994-1001. Epub 2015 Apr 15.

From the Istituto Giannina Gaslini, Genoa, Italy; Karolinska University Hospital Solna, Stockholm, Sweden; Gulhane Military Medical Faculty, Ankara, Turkey; Royal Children's Hospital, Melbourne, Australia; Bakırkoy Maternity and Children Education and Research Hospital, Istanbul, Turkey; King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; Policlinico Università di Catania, Catania, Italy; Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil; Universitaetsklinik fuer Kinderheilkunde, Inselspital, Berne, Switzerland; Ospedale Policlinico, Chieti, Italy; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico; University of Messina, Messina, Italy; Carolinas HealthCare System, Charlotte, North Carolina; Women and Children's Hospital, Buffalo, New York, USA; Zentrum fuer Allgemeine Paediatrie und Neonatologie, Sankt Augustin, Germany; Stanford School of Medicine, Palo Alto, California, USA; Department for Immunology and Rheumatology, Children's Hospital of Zagreb, Zagreb, Croatia; Steven and Alexandra Cohen Children's Hospital of New York, New York, New York, USA; IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy; University of Latvia, Riga, Latvia; Hospital das Clínicas, Botucatu, Brazil; King Fahad National Guard Hospital, Riyadh, Saudi Arabia; Arkansas Children's Hospital, Little Rock, Arkansas, USA; Kyriakou Children's Hospital of Athens, Athens, Greece; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Children's University Hospital, Riga, Latvia; Hospital Universitario 12 de Octubre, Madrid, Spain; M. Iashvili Children's Central Clinic, Tbilisi, Georgia; Azienda Ospedaliera Universitaria Ospedali Riuniti, Ancona, Italy; Gazi University, Ankara, Turkey; Università degli Studi di Genova, Genoa, Italy; University of Alabama at Birmingham, Birmingham, Alabama, USA.F. Minoia, MD; S. Davì, MD, Istituto Giannina Gaslini; A. Horne, M

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June 2015

Hyperinflammation, rather than hemophagocytosis, is the common link between macrophage activation syndrome and hemophagocytic lymphohistiocytosis.

Curr Opin Rheumatol 2014 Sep;26(5):562-9

Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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September 2014

Chronic non-bacterial osteomyelitis in a patient with common variable immunodeficiency.

Joint Bone Spine 2014 Mar 20;81(2):193-4. Epub 2013 Sep 20.

Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, USA; Division of Allergy and Immunology, The Children's Hospital of Philadelphia, 3615 Civic Center Boulevard, Abramson Research Center 1214, Philadelphia, PA 19104, USA.

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March 2014

How to use... antinuclear antibodies in paediatric rheumatic diseases.

Arch Dis Child Educ Pract Ed 2013 Apr;98(2):64-70

Department of Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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April 2013

Up-regulation of human monocyte CD163 upon activation of cell-surface Toll-like receptors.

J Leukoc Biol 2007 Mar 12;81(3):663-71. Epub 2006 Dec 12.

Department of Microbiology and Immunology, Dartmouth Medical School, HB7700, Lebanon, NH 03756, USA.

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March 2007

BCMA is essential for the survival of long-lived bone marrow plasma cells.

J Exp Med 2004 Jan;199(1):91-8

Department of Microbiology and Immunology, Dartmouth Medical School, 1 Medical Center Drive, Lebanon, NH 03756, USA.

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January 2004