Lefkos Middleton

Lefkos Middleton

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Lefkos Middleton

Publications by authors named "Lefkos Middleton"

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Differential expression of microRNAs in Alzheimer's disease brain, blood, and cerebrospinal fluid.

Alzheimers Dement 2019 11 5;15(11):1468-1477. Epub 2019 Sep 5.

Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK; Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institutes of Neurogenetics & Cardiogenetics, University of Lübeck, Lübeck, Germany; Department of Psychology, University of Oslo, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.06.4952DOI Listing
November 2019

Perspective: Clinical relevance of the dichotomous classification of Alzheimer's disease biomarkers: Should there be a "gray zone"?

Alzheimers Dement 2019 10 26;15(10):1348-1356. Epub 2019 Sep 26.

Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.07.010DOI Listing
October 2019

Meta-analyses identify differentially expressed micrornas in Parkinson's disease.

Ann Neurol 2019 06;85(6):835-851

Genetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics & Cardiogenetics, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1002/ana.25490DOI Listing
June 2019

Use of Online Dietary Recalls among Older UK Adults: A Feasibility Study of an Online Dietary Assessment Tool.

Nutrients 2019 Jun 27;11(7). Epub 2019 Jun 27.

Department of Neuroepidemiology and Ageing, School of Public Health, Imperial College London, London W6 8RP, UK.

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http://dx.doi.org/10.3390/nu11071451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682978PMC
June 2019

Cortisol, Amyloid-β, and Reserve Predicts Alzheimer's Disease Progression for Cognitively Normal Older Adults.

J Alzheimers Dis 2019 ;70(2):553-562

Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology and Medicine, London, UK.

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http://dx.doi.org/10.3233/JAD-181030DOI Listing
January 2019

α-Synuclein: Multiple System Atrophy Prions.

Cold Spring Harb Perspect Med 2018 07 2;8(7). Epub 2018 Jul 2.

Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California 94158.

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http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
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http://dx.doi.org/10.1101/cshperspect.a024588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561534PMC
July 2018

MSA prions exhibit remarkable stability and resistance to inactivation.

Acta Neuropathol 2018 01 28;135(1):49-63. Epub 2017 Aug 28.

Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1007/s00401-017-1762-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756500PMC
January 2018

Systematic evaluation of the associations between environmental risk factors and dementia: An umbrella review of systematic reviews and meta-analyses.

Alzheimers Dement 2017 Apr 4;13(4):406-418. Epub 2016 Sep 4.

Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.07.152DOI Listing
April 2017

Associations between TOMM40 Poly-T Repeat Variants and Dementia in Cases with Parkinsonism.

J Parkinsons Dis 2016 ;6(1):99-108

Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.3233/JPD-150693DOI Listing
January 2017

Is the time ripe for new diagnostic criteria of cognitive impairment due to cerebrovascular disease? Consensus report of the International Congress on Vascular Dementia working group.

BMC Med 2016 Nov 3;14(1):162. Epub 2016 Nov 3.

Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology and Medicine, Charing Cross Hospital, St Dunstan's Road, W6 8RP, London, UK.

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http://dx.doi.org/10.1186/s12916-016-0719-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093932PMC
November 2016

α-synuclein genetic variability: A biomarker for dementia in Parkinson disease.

Ann Neurol 2016 Jun 5;79(6):991-9. Epub 2016 May 5.

Centre for Applied Neurogenetics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://doi.wiley.com/10.1002/ana.24664
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http://dx.doi.org/10.1002/ana.24664DOI Listing
June 2016

Why has therapy development for dementia failed in the last two decades?

Alzheimers Dement 2016 Jan 19;12(1):60-4. Epub 2015 Dec 19.

Neuroepidemiology and Ageing Research, School of Public Health, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2015.12.003DOI Listing
January 2016

Propagation of prions causing synucleinopathies in cultured cells.

Proc Natl Acad Sci U S A 2015 Sep 18;112(35):E4949-58. Epub 2015 Aug 18.

Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94143; Department of Neurology, University of California, San Francisco, CA 94143; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143

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http://dx.doi.org/10.1073/pnas.1513426112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568231PMC
September 2015

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.

Proc Natl Acad Sci U S A 2015 Sep 31;112(38):E5308-17. Epub 2015 Aug 31.

Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94143; Department of Neurology, University of California, San Francisco, CA 94143;

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http://dx.doi.org/10.1073/pnas.1514475112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586853PMC
September 2015

Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study.

Br J Psychiatry 2014 Jul 8;205(1):24-8. Epub 2014 May 8.

Chi-Fa Hung, MD, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry at King's College London, UK, and Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Margarita Rivera, PhD, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry at King's College London, UK, and CIBERSAM, University of Granada, Section of Psychiatry, Institute of Neurosciences, Biomedical Research Centre (CIBM), Granada, Spain; Nick Craddock, PhD, FRCPsych, FMedSci, Michael J. Owen, PhD, FRCPsych, FMedSci, Department of Psychological Medicine, School of Medicine, Cardiff University, UK; Michael Gill, PhD, Department of Psychiatry, Trinity Centre for Health Sciences, St James' Hospital, Dublin, Ireland; Ania Korszun, PhD, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary's University of London, UK; Wolfgang Maier, PhD, Psychiatrie und Psychotherapie, Universitätsklinikum Bonn, Bonn, Germany; Ole Mors, PhD, Research Department P, Aarhus University Hospital, Risskov, Aarhus, Denmark; Martin Preisig, MD, Department of Adult Psychiatry, University Hospital of Lausanne, Prilly-Lausanne, Switzerland; John P. Rice, PhD, Department of Psychiatry, Washington University, St Louis, Missouri, USA; Marcella Rietschel, MD, Central Institute of Mental Health, Mannheim, Germany; Lisa Jones, PhD, Department of Psychiatry, School of Clinical and Experimental Medicine, University of Birmingham, UK; Lefkos Middleton, MD,Division of Neuroscience and Mental Health, Imperial College London, UK; Kathy J. Aitchison, PhD, MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry at King's College London, UK and Department of Psychiatry, University of Alberta, Alberta, Canada; Oliver S. P. Davis, PhD, University College London Genetics Institute, Department of Genetics, Evolution and Environment, University Colleg

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https://www.cambridge.org/core/product/identifier/S000712500
Publisher Site
http://dx.doi.org/10.1192/bjp.bp.113.130419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076654PMC
July 2014

A novel GBA2 gene missense mutation in spastic ataxia.

Ann Hum Genet 2014 Jan 20;78(1):13-22. Epub 2013 Nov 20.

The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1111/ahg.12045DOI Listing
January 2014

Transmission of multiple system atrophy prions to transgenic mice.

Proc Natl Acad Sci U S A 2013 Nov 11;110(48):19555-60. Epub 2013 Nov 11.

Institute for Neurodegenerative Diseases, and Departments of Neurology and Pathology, University of California, San Francisco, CA 94143.

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http://dx.doi.org/10.1073/pnas.1318268110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845125PMC
November 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.2711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

A mega-analysis of genome-wide association studies for major depressive disorder.

Authors:
Stephan Ripke Naomi R Wray Cathryn M Lewis Steven P Hamilton Myrna M Weissman Gerome Breen Enda M Byrne Douglas H R Blackwood Dorret I Boomsma Sven Cichon Andrew C Heath Florian Holsboer Susanne Lucae Pamela A F Madden Nicholas G Martin Peter McGuffin Pierandrea Muglia Markus M Noethen Brenda P Penninx Michele L Pergadia James B Potash Marcella Rietschel Danyu Lin Bertram Müller-Myhsok Jianxin Shi Stacy Steinberg Hans J Grabe Paul Lichtenstein Patrik Magnusson Roy H Perlis Martin Preisig Jordan W Smoller Kari Stefansson Rudolf Uher Zoltan Kutalik Katherine E Tansey Alexander Teumer Alexander Viktorin Michael R Barnes Thomas Bettecken Elisabeth B Binder René Breuer Victor M Castro Susanne E Churchill William H Coryell Nick Craddock Ian W Craig Darina Czamara Eco J De Geus Franziska Degenhardt Anne E Farmer Maurizio Fava Josef Frank Vivian S Gainer Patience J Gallagher Scott D Gordon Sergey Goryachev Magdalena Gross Michel Guipponi Anjali K Henders Stefan Herms Ian B Hickie Susanne Hoefels Witte Hoogendijk Jouke Jan Hottenga Dan V Iosifescu Marcus Ising Ian Jones Lisa Jones Tzeng Jung-Ying James A Knowles Isaac S Kohane Martin A Kohli Ania Korszun Mikael Landen William B Lawson Glyn Lewis Donald Macintyre Wolfgang Maier Manuel Mattheisen Patrick J McGrath Andrew McIntosh Alan McLean Christel M Middeldorp Lefkos Middleton Grant M Montgomery Shawn N Murphy Matthias Nauck Willem A Nolen Dale R Nyholt Michael O'Donovan Högni Oskarsson Nancy Pedersen William A Scheftner Andrea Schulz Thomas G Schulze Stanley I Shyn Engilbert Sigurdsson Susan L Slager Johannes H Smit Hreinn Stefansson Michael Steffens Thorgeir Thorgeirsson Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Henry Völzke Jeffrey B Weilburg Gonneke Willemsen Frans G Zitman Benjamin Neale Mark Daly Douglas F Levinson Patrick F Sullivan

Mol Psychiatry 2013 Apr 3;18(4):497-511. Epub 2012 Apr 3.

Harvard University/Broad Institute, USA.

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http://dx.doi.org/10.1038/mp.2012.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837431PMC
April 2013

A novel LRSAM1 mutation is associated with autosomal dominant axonal Charcot-Marie-Tooth disease.

Eur J Hum Genet 2013 Feb 11;21(2):190-4. Epub 2012 Jul 11.

Neurogenetics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1038/ejhg.2012.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548253PMC
February 2013

Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

Authors:
Jason Z Liu Federica Tozzi Dawn M Waterworth Sreekumar G Pillai Pierandrea Muglia Lefkos Middleton Wade Berrettini Christopher W Knouff Xin Yuan Gérard Waeber Peter Vollenweider Martin Preisig Nicholas J Wareham Jing Hua Zhao Ruth J F Loos Inês Barroso Kay-Tee Khaw Scott Grundy Philip Barter Robert Mahley Antero Kesaniemi Ruth McPherson John B Vincent John Strauss James L Kennedy Anne Farmer Peter McGuffin Richard Day Keith Matthews Per Bakke Amund Gulsvik Susanne Lucae Marcus Ising Tanja Brueckl Sonja Horstmann H-Erich Wichmann Rajesh Rawal Norbert Dahmen Claudia Lamina Ozren Polasek Lina Zgaga Jennifer Huffman Susan Campbell Jaspal Kooner John C Chambers Mary Susan Burnett Joseph M Devaney Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Stephen Epstein James F Wilson Sarah H Wild Harry Campbell Veronique Vitart Muredach P Reilly Mingyao Li Liming Qu Robert Wilensky William Matthai Hakon H Hakonarson Daniel J Rader Andre Franke Michael Wittig Arne Schäfer Manuela Uda Antonio Terracciano Xiangjun Xiao Fabio Busonero Paul Scheet David Schlessinger David St Clair Dan Rujescu Gonçalo R Abecasis Hans Jörgen Grabe Alexander Teumer Henry Völzke Astrid Petersmann Ulrich John Igor Rudan Caroline Hayward Alan F Wright Ivana Kolcic Benjamin J Wright John R Thompson Anthony J Balmforth Alistair S Hall Nilesh J Samani Carl A Anderson Tariq Ahmad Christopher G Mathew Miles Parkes Jack Satsangi Mark Caulfield Patricia B Munroe Martin Farrall Anna Dominiczak Jane Worthington Wendy Thomson Steve Eyre Anne Barton Vincent Mooser Clyde Francks Jonathan Marchini

Nat Genet 2010 May 25;42(5):436-40. Epub 2010 Apr 25.

Department of Statistics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612983PMC
May 2010

Factor structure and external validity of the PANSS revisited.

Schizophr Res 2006 Feb 17;82(2-3):213-23. Epub 2005 Oct 17.

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia of Virginia Commonwealth University, P.O. Box 980126, Richmond VA 23298-0126, USA.

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http://ac.els-cdn.com/S0920996405003981/1-s2.0-S092099640500
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http://linkinghub.elsevier.com/retrieve/pii/S092099640500398
Publisher Site
http://dx.doi.org/10.1016/j.schres.2005.09.002DOI Listing
February 2006

Whole genome linkage scan of recurrent depressive disorder from the depression network study.

Hum Mol Genet 2005 Nov 3;14(22):3337-45. Epub 2005 Oct 3.

Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, UK.

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http://dx.doi.org/10.1093/hmg/ddi363DOI Listing
November 2005

Pharmacogenetics in drug development.

Philos Trans R Soc Lond B Biol Sci 2005 Aug;360(1460):1579-88

Translational Medicine & Genetics, GlaxoSmithKline, Greenford Road, Greenford, Middlesex UB6 0HE, UK.

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http://dx.doi.org/10.1098/rstb.2005.1688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569527PMC
August 2005

Disease-specific target selection: a critical first step down the right road.

Drug Discov Today 2005 Feb;10(3):177-89

GlaxoSmithKline R&D, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/S1359-6446(04)03321-5DOI Listing
February 2005

A novel NF-L mutation Pro22Ser is associated with CMT2 in a large Slovenian family.

Neurogenetics 2002 Oct;4(2):93-6

The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1007/s10048-002-0138-4DOI Listing
October 2002