Lee A Denson

Lee A Denson

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Lee A Denson

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Shared decision making in IBD: A novel approach to trial consent and timing.

Contemp Clin Trials Commun 2019 Dec 8;16:100447. Epub 2019 Sep 8.

James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1016/j.conctc.2019.100447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745512PMC
December 2019

Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.

Cell 2019 Sep 29;178(6):1493-1508.e20. Epub 2019 Aug 29.

Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.08.008DOI Listing
September 2019

Improving IBD Transition, Self-management, and Disease Outcomes With an In-clinic Transition Coordinator.

J Pediatr Gastroenterol Nutr 2019 Aug;69(2):194-199

Cincinnati Children's Hospital Medical Center, Schubert-Martin Pediatric IBD Center.

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http://dx.doi.org/10.1097/MPG.0000000000002350DOI Listing
August 2019

Longitudinal non-adherence predicts treatment escalation in paediatric ulcerative colitis.

Aliment Pharmacol Ther 2019 Aug 2. Epub 2019 Aug 2.

Cincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology, Cincinnati, OH, USA.

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http://dx.doi.org/10.1111/apt.15445DOI Listing
August 2019

Serologic, but not Genetic, Markers are Associated with Impaired Anthropometrics at Diagnosis of Pediatric Crohn's Disease.

J Pediatr Gastroenterol Nutr 2019 Aug 6. Epub 2019 Aug 6.

Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1097/MPG.0000000000002462DOI Listing
August 2019

Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation.

J Pediatr 2019 Jul 23;210:220-225. Epub 2019 Apr 23.

Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA; Pediatric Institute, Children's Healthcare of Atlanta, Atlanta, GA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223476193039
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http://dx.doi.org/10.1016/j.jpeds.2019.03.042DOI Listing
July 2019

Development of Infliximab Target Concentrations During Induction in Pediatric Crohn Disease Patients.

J Pediatr Gastroenterol Nutr 2019 Jul;69(1):68-74

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://dx.doi.org/10.1097/MPG.0000000000002304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607916PMC
July 2019

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.

Gastroenterology 2019 06 16;156(8):2254-2265.e3. Epub 2019 Feb 16.

Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Human Genetics, Emory University, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.01.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529254PMC
June 2019

Genetic variants in acute, acute recurrent and chronic pancreatitis affect the progression of disease in children.

Pancreatology 2019 Jun 7;19(4):535-540. Epub 2019 May 7.

Cincinnati Children's Hospital Medical Center, Gastroenterology, Hepatology & Nutrition, 3333 Burnet Ave, Cincinnati, OH, 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14243903193010
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http://dx.doi.org/10.1016/j.pan.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589390PMC
June 2019

Evaluation of a Novel Educational Tool in Adolescents with Inflammatory Bowel Disease: The NEAT Study.

J Pediatr Gastroenterol Nutr 2019 Jun 28. Epub 2019 Jun 28.

Cincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology.

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http://dx.doi.org/10.1097/MPG.0000000000002431DOI Listing
June 2019

Bowel Location Rather Than Disease Subtype Dominates Transcriptomic Heterogeneity in Pediatric IBD.

Cell Mol Gastroenterol Hepatol 2018 1;6(4):474-476.e3. Epub 2018 Aug 1.

Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X183010
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http://dx.doi.org/10.1016/j.jcmgh.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198018PMC
April 2019

Rapid Progression of Acute Pancreatitis to Acute Recurrent Pancreatitis in Children.

J Pediatr Gastroenterol Nutr 2019 Jan;68(1):104-109

Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center.

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http://dx.doi.org/10.1097/MPG.0000000000002145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310081PMC
January 2019

Interleukin-22 levels are increased in gastrointestinal graft--host disease in children.

Haematologica 2018 Oct 17;103(10):e480-e482. Epub 2018 May 17.

Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, OH, USA.

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http://dx.doi.org/10.3324/haematol.2017.174771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165817PMC
October 2018

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children.

Am J Gastroenterol 2018 10 28;113(10):1524-1529. Epub 2018 Sep 28.

Division of Pediatric Gastroenterology, Emory University School of Medicine, Atlanta, GA, USA. Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA. Department of Pediatric Gastroenterology, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH, USA. Department of Gastroenterology and Nutrition, Boston Children's Hospital, Boston, MA, USA. Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Department of Pediatrics, Goryeb Children's Hospital, Morristown, NJ, USA. Division of Pediatric Gastroenterology, Hasbro Children's Hospital/The Rhode Island Hospital, Providence, RI, USA. Department of Pediatrics, University of Utah, Salt Lake City, UT, USA. Department of Pediatrics, Children's Hospital of Eastern Ontario IBD Centre and University of Ottawa, Ottawa, ON, Canada. Section of Pediatric Gastroenterology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA. Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA. Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA. Department of Gastroenterology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA. Children's Healthcare of Atlanta, Atlanta, GA, USA. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Department of Pediatrics, Dalhousie University, Halifax, NS, Canada. Department of Digestive Diseases and Nutrition Center, University at Buffalo, Buffalo, NY, USA. Department of Pediatrics, Nemours Children's Specialty Care, Jacksonville, FL, USA. Department of Pediatrics, University of Chicago Medicine Comer Children's Hospital, Chicago, IL, USA. Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Department of Pediatric Gastroenterology, Mayo Clinic, Rochester, MN, USA. Department of Pediatrics, University of Pennsylvania, Philadelphia, PA, USA. Department of Pediatrics, Mount Sinai Hospital, New York, NY, USA. Department of Pediatrics, Northwell Health, New York, NY, USA. Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, CT, USA. Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41395-018-0239-9DOI Listing
October 2018

Multi-Site Comparison of Patient, Parent, and Pediatric Provider Perspectives on Transition to Adult Care in IBD.

J Pediatr Nurs 2018 Mar - Apr;39:49-54. Epub 2018 Feb 3.

Cincinnati Children's Hospital Medical Center, Division of Behavioral Medicine & Clinical Psychology, Cincinnati, OH, United States; University of Cincinnati College of Medicine, Department of Pediatrics, Cincinnati, OH, United States.

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http://dx.doi.org/10.1016/j.pedn.2018.01.008DOI Listing
September 2018

Penetrating Crohn disease: does it occur in the absence of stricturing disease?

Abdom Radiol (NY) 2018 07;43(7):1583-1589

Department of Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1007/s00261-017-1398-7DOI Listing
July 2018

Validation of Neutrophil CD64 Blood Biomarkers to Detect Mucosal Inflammation in Pediatric Crohn's Disease.

Inflamm Bowel Dis 2017 12;24(1):198-208

Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1093/ibd/izx022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831176PMC
December 2017

Longitudinal Patterns of Medication Nonadherence and Associated Health Care Costs.

Inflamm Bowel Dis 2017 09;23(9):1577-1583

*Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; †Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio; and ‡Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/MIB.0000000000001165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561465PMC
September 2017

Exclusive and partial enteral nutrition for Crohn's disease - Authors' reply.

Lancet 2017 09;390(10101):1486-1487

Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, CT, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)32157-8DOI Listing
September 2017

Cytokine Patterns in Healthy Adolescent Girls: Heterogeneity Captured by Variable and Person-Centered Statistical Strategies.

Psychosom Med 2016 Jul-Aug;78(6):646-56

From the College of Nursing (Dorn, Engeland), The Pennsylvania State University; Prevention Research Center (Gayles), The Pennsylvania State University; Department of Biobehavioral Health (Engeland), The Pennsylvania State University, University Park, Pennsylvania; Department of Psychology and Neuroscience (Houts), Duke University, Durham, North Carolina; National Institute of Child Health and Human Development (Cizza), National Institutes of Health, Bethesda, Maryland; Pediatric Gastroenterology (Denson), Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; and University of Cincinnati School of Medicine (Denson), Cincinnati, Ohio.

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https://insights.ovid.com/crossref?an=00006842-201607000-000
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http://dx.doi.org/10.1097/PSY.0000000000000321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927350PMC
July 2017

Early Elevation in Interleukin-6 is Associated with Reduced Growth in Extremely Low Birth Weight Infants.

Am J Perinatol 2017 Feb 25;34(3):240-247. Epub 2016 Jul 25.

Division of Perinatal Medicine, Department of Pediatrics, Yale-New Haven Children's Hospital and the Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1055/s-0036-1585419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296404PMC
February 2017

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

Gastroenterology 2017 01 28;152(1):206-217.e2. Epub 2016 Sep 28.

Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164948PMC
January 2017

High Levels of Decisional Conflict and Decision Regret When Making Decisions About Biologics.

J Pediatr Gastroenterol Nutr 2016 12;63(6):e176-e181

*Division of Adolescent and Transition Medicine, Department of Pediatrics †Department of Pediatrics, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center ‡University of Cincinnati College of Medicine §Division of Rheumatology ||Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati ¶Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Nationwide Children's Hospital #The Ohio State College of Medicine **Division of Rheumatology, Department of Pediatrics, Nationwide Children's Hospital, Columbus ††Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://dx.doi.org/10.1097/MPG.0000000000001425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123667PMC
December 2016

A Low Neutrophil CD64 Index Is Associated with Sustained Remission During Infliximab Maintenance Therapy.

Inflamm Bowel Dis 2016 11;22(11):2641-2647

*Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; †Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio; and ‡Division of Cellular and Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1097/MIB.0000000000000922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117809PMC
November 2016

Granulocyte-Macrophage Colony Stimulating Factor Bioactivity and Mucosal Homeostasis in Crohn's Disease: A Role for Genetic Variation.

Gastroenterology 2016 10 30;151(4):593-6. Epub 2016 Aug 30.

Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München, Munich, Germany.

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http://dx.doi.org/10.1053/j.gastro.2016.08.042DOI Listing
October 2016

Parents' information needs and influential factors when making decisions about TNF-α inhibitors.

Pediatr Rheumatol Online J 2016 Sep 15;14(1):53. Epub 2016 Sep 15.

Division of Adolescent and Transition Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1186/s12969-016-0113-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024421PMC
September 2016

Importance of the Evaluation of N-Acetyltransferase Enzyme Activity Prior to 5-Aminosalicylic Acid Medication for Ulcerative Colitis.

Inflamm Bowel Dis 2016 08;22(8):1793-802

*Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio;†Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio;‡Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio; and§Division of Digestive Disease, Department of Internal Medicine, University of Cincinnati, Ohio.

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http://dx.doi.org/10.1097/MIB.0000000000000823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956520PMC
August 2016

Making decisions about chronic disease treatment: a comparison of parents and their adolescent children.

Health Expect 2016 06 3;19(3):716-26. Epub 2014 Jun 3.

Center for Innovation in Chronic Disease Care, Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1111/hex.12210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055230PMC
June 2016

Serum Infliximab, Antidrug Antibodies, and Tumor Necrosis Factor Predict Sustained Response in Pediatric Crohn's Disease.

Inflamm Bowel Dis 2016 06;22(6):1370-7

*Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; †Department of Gastroenterology, Seattle Children's Hospital, Seattle, Washington; ‡Departments of Pediatrics and Medicine, Division of Nephrology, Stanford University School of Medicine, Stanford, California; §Janssen Pharmaceuticals, Horsham, Pennsylvania; ‖Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; ¶Nestlé Health Science, Vevey, Switzerland; #Department of Pediatrics, Division of Nephrology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; and **Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/MIB.0000000000000769DOI Listing
June 2016

Practical Use of Infliximab Concentration Monitoring in Pediatric Crohn Disease.

J Pediatr Gastroenterol Nutr 2016 05;62(5):715-22

*Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH †Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan ‡Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://dx.doi.org/10.1097/MPG.0000000000001029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842082PMC
May 2016

Physicians' Perceptions of Shared Decision Making in Chronic Disease and Its Barriers and Facilitators.

J Pediatr 2016 Apr 23;171:307-9.e1-2. Epub 2016 Jan 23.

Center for Innovation in Chronic Disease Care, Division of Adolescent and Transition Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; University of Cincinnati College of Medicine, Cincinnati, OH. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2015.12.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808590PMC
April 2016

IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function.

Inflamm Bowel Dis 2015 Dec;21(12):2737-46

*Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; †Division of Pediatric Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee; ‡Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; §Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; ‖Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; ¶Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee; **Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee; ††Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee; and ‡‡The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1097/MIB.0000000000000532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654638PMC
December 2015

Altered cGMP dynamics at the plasma membrane contribute to diarrhea in ulcerative colitis.

Am J Pathol 2015 Oct 8;185(10):2790-804. Epub 2015 Aug 8.

Division of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607763PMC
October 2015

Epithelial Reactive Oxygen Species and Risk for Very Early Onset Inflammatory Bowel Disease.

Authors:
Lee A Denson

Cell Mol Gastroenterol Hepatol 2015 Sep 29;1(5):456-457. Epub 2015 Jul 29.

Division of Gastroenterology, Hepatology and Nutrition, Schubert-Martin Pediatric IBD Center, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

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http://dx.doi.org/10.1016/j.jcmgh.2015.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301400PMC
September 2015

Diagnostic Performance and Dose Comparison of Filtered Back Projection and Adaptive Iterative Dose Reduction Three-dimensional CT Enterography in Children and Young Adults.

Radiology 2015 Jul 4;276(1):233-42. Epub 2015 Feb 4.

From the Department of Radiology (D.B.W., D.J.P., J.S., A.J.T.), Department of Pediatrics, Division of Gastroenterology (L.A.D.), and Department of Biostatistics and Epidemiology (B.Z., S.R.S.), Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, ML 5031, Cincinnati, OH 45241.

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http://dx.doi.org/10.1148/radiol.14140468DOI Listing
July 2015

Improvements in Bone Density and Structure during Anti-TNF-α Therapy in Pediatric Crohn's Disease.

J Clin Endocrinol Metab 2015 Jul 28;100(7):2630-9. Epub 2015 Apr 28.

Department of Radiology (L.M.G.), New York University School of Medicine, New York, New York 10016; Janssen Pharmaceuticals (M.T.), Titusville, New Jersey 08560; Department of Pediatrics (R.N.B., B.S.Z., M.R.D., J.S., R.H., J.L., M.B.L.), The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104; Department of Pediatrics (M.D.D.), University of Virginia Health System, Charlottesville, Virginia 22908; Department of Pediatrics (L.A.D.), Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229; Department of Biostatistics and Epidemiology (J.S., M.B.L.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104; and Department of Pediatrics (M.B.L.), Stanford University Medical Center, Stanford, California 94025.

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http://dx.doi.org/10.1210/jc.2014-4152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490303PMC
July 2015

Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes.

Hum Mol Genet 2015 Jul 1;24(14):4147-57. Epub 2015 May 1.

Department of Genetics and Genomic Sciences, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA,

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http://dx.doi.org/10.1093/hmg/ddv142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560067PMC
July 2015

Concerns, Barriers, and Recommendations to Improve Transition from Pediatric to Adult IBD Care: Perspectives of Patients, Parents, and Health Professionals.

Inflamm Bowel Dis 2015 Jul;21(7):1641-51

*Department of Psychology, Auburn University, Auburn, Alabama; †Division of Gastroenterology, Hepatology and Nutrition, Schubert-Martin Pediatric IBD Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; ‡Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; and §Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

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http://dx.doi.org/10.1097/MIB.0000000000000419DOI Listing
July 2015

Health-related quality of life in youth with Crohn disease: role of disease activity and parenting stress.

J Pediatr Gastroenterol Nutr 2015 Jun;60(6):749-53

*Department of Psychology, Auburn University, Auburn, AL †Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH ‡Department of Clinical & Health Psychology, University of Florida §Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Florida Health, Gainesville ||Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Schubert-Martin Inflammatory Bowel Disease Center, Cincinnati, OH ¶Division of Gastroenterology, Hepatology, and Nutrition, Center for Pediatric Inflammatory Bowel Disease, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1097/MPG.0000000000000696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441543PMC
June 2015

Transition readiness skills acquisition in adolescents and young adults with inflammatory bowel disease: findings from integrating assessment into clinical practice.

Inflamm Bowel Dis 2015 May;21(5):1125-31

*Department of Psychology, Auburn University, Auburn, Alabama; †Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; ‡Schubert-Martin Pediatric IBD Center, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; and §Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

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http://dx.doi.org/10.1097/MIB.0000000000000352DOI Listing
May 2015

CT and MR enterography in children and adolescents with inflammatory bowel disease.

Radiographics 2013 Nov-Dec;33(7):1843-60

From the Departments of Radiology (A.J.T., J.S., D.B.W., D.J.P.) and Gastroenterology (L.A.D.), Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, ML 5031, Cincinnati, OH 45241.

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http://dx.doi.org/10.1148/rg.337105140DOI Listing
June 2014

Changes in vitamin D-related mineral metabolism after induction with anti-tumor necrosis factor-α therapy in Crohn's disease.

J Clin Endocrinol Metab 2014 Jun 11;99(6):E991-8. Epub 2014 Mar 11.

The Children's Hospital of Philadelphia (M.V.A., M.B.L., M.T., R.N.B., J.S., R.H., M.R.D.), Perelman School of Medicine at the University of Pennsylvania (M.B.L., R.N.B., J.S., M.R.D.), Philadelphia, Pennsylvania 19104; Kidney Research Institute, University of Washington (I.H.d.B.), Seattle, Washington 98104; Department of Pediatrics, Cincinnati Children's Hospital Medical Center (L.A.D.), Cincinnati, Ohio 45229; and Department of Pediatrics, University of Virginia Health System (M.D.D.), Charlottesville, Virginia 22908.

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http://dx.doi.org/10.1210/jc.2013-3846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037735PMC
June 2014

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Jun;20(6):1037-48

1Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Divisions of 2Allergy and Immunology and 3Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; 4Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; 5Division of Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; 6Division of Pediatric Gastroenterology and Nutrition, Cohen Children's Medical Center of New York, New Hyde Park, New York; 7Department of Pediatric Gastroenterology and Nutrition, Goryeb Children's Hospital/Atlantic Health System, Morristown, New Jersey; 8Division of Pediatric Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, Columbus, Ohio; 9Department of Pediatrics, University of California, San Francisco, San Francisco, California; 10Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; 11Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; 12Digestive Diseases and Nutrition Center, Department of Pediatrics, University at Buffalo, Buffalo, New York; 13Division of Digestive Diseases and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut; and 14Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1097/MIB.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151275PMC
June 2014

Salivary cytokines in healthy adolescent girls: Intercorrelations, stability, and associations with serum cytokines, age, and pubertal stage.

Dev Psychobiol 2014 May 19;56(4):797-811. Epub 2013 Jul 19.

Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1002/dev.21149DOI Listing
May 2014

Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease.

J Pediatr Gastroenterol Nutr 2014 May;58(5):561-8

*Department of Pediatrics †Department of Human Genetics, Emory University School of Medicine, Atlanta, GA ‡Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN §Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://dx.doi.org/10.1097/MPG.0000000000000302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277865PMC
May 2014

Assessing psychosocial risk in pediatric inflammatory bowel disease: validation of the Psychosocial Assessment Tool 2.0_General.

J Pediatr Gastroenterol Nutr 2014 Jan;58(1):51-6

*Center for Treatment Adherence and Self-Management †Division of Behavioral Medicine and Clinical Psychology ‡Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, OH.

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http://dx.doi.org/10.1097/MPG.0b013e3182a938b7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885900PMC
January 2014

NASPGHAN single-topic symposium: discovering the future of pediatric IBD care.

J Pediatr Gastroenterol Nutr 2014 Jan;58(1):130-8

*Division of Gastroenterology, Nationwide Children's Hospital, Columbus, OH †The Children's Hospital of Philadelphia, Philadelphia, PA ‡Pediatric Gastroenterology, Boston Children's Hospital, Boston, MA §Pediatric Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH ||Pediatric Gastroenterology, New York-Presbyterian Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY ¶Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, OH.

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http://dx.doi.org/10.1097/MPG.0000000000000178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889135PMC
January 2014

Report of the CCFA pediatric bone, growth and muscle health workshop, New York City, November 11-12, 2011, with updates.

Inflamm Bowel Dis 2013 Dec;19(13):2919-26

*Connecticut Children's Medical Center, Hartford, CT and University of Connecticut Health Center, Farmington, CT; †Children's Hospital Boston, Harvard University, Boston, MA; ‡Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; §Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ‖University Hospital of Geneva, Geneva, Switzerland; ¶University of California San Francisco Children's Hospital, San Francisco, CA and UCLA/Orthopaedic Hospital, Los Angeles, CA; **Dr. von Haunersches Kinderspital, Ludwig Maximilians Universität München, Germany; ††Michigan State University, East Lansing, MI; ‡‡Royal London Hospital, Bart's & London School of Medicine, London, United Kingdom; §§Children's Hospital of Eastern Ontario, Ontario, Canada; and ‖‖Saint Francis Hospital and Medical Center, Hartford CT and University of Connecticut Health Center, Farmington, CT.

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December 2013

Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease.

Am J Gastroenterol 2013 Dec 22;108(12):1901-10. Epub 2013 Oct 22.

1] Department of Pediatric Rheumatology and Immunology, University Children's Hospital Münster, Münster, Germany [2] Interdisciplinary Center of Clinical Research, University of Münster, Münster, Germany [3] The Royal Children's Hospital Melbourne, Murdoch Children's Research Institute, Parkville, Victoria, Australia [4] Department of Pediatrics, University of Melbourne, Melboure Medical School, Parkville, Victoria, Australia.

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http://www.nature.com/articles/ajg2013360
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http://dx.doi.org/10.1038/ajg.2013.360DOI Listing
December 2013

Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice.

Vaccine 2013 Dec 6;32(1):48-53. Epub 2013 Nov 6.

Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, University of Cincinnati, OH, USA; Center for Global Child Health, Cincinnati Children's Hospital Medical Center, University of Cincinnati, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2013.10.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887447PMC
December 2013

The clinical utility of health-related quality of life screening in a pediatric inflammatory bowel disease clinic.

Inflamm Bowel Dis 2013 Nov;19(12):2666-72

*Department of Psychology, Oklahoma State University, Stillwater, Oklahoma; †Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; ‡Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; §Center for the Promotion of Treatment Adherence and Self-Management, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; and ‖Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1097/MIB.0b013e3182a82b15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863996PMC
November 2013

Development and reliability of a correction factor for family-reported medication adherence: pediatric inflammatory bowel disease as an exemplar.

J Pediatr Psychol 2013 Sep 26;38(8):893-901. Epub 2013 Jun 26.

Division of Behavioral Medicine and Clinical Psychology, Center for Adherence and Self-Management, MLC-7039, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/jpepsy/jst043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859234PMC
September 2013

The role of the innate and adaptive immune system in pediatric inflammatory bowel disease.

Authors:
Lee A Denson

Inflamm Bowel Dis 2013 Aug;19(9):2011-20

Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1097/MIB.0b013e318281f590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077715PMC
August 2013

Delays in puberty, growth, and accrual of bone mineral density in pediatric Crohn's disease: despite temporal changes in disease severity, the need for monitoring remains.

J Pediatr 2013 Jul 22;163(1):17-22. Epub 2013 Mar 22.

Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1016/j.jpeds.2013.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692567PMC
July 2013

Linking genetic variation to phenotype: eQTL analysis of normal human ileum.

Authors:
Lee A Denson

Gastroenterology 2013 Jun 24;144(7):1339-41. Epub 2013 Apr 24.

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http://dx.doi.org/10.1053/j.gastro.2013.04.025DOI Listing
June 2013

Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.

J Immunol 2013 May 5;190(9):4773-85. Epub 2013 Apr 5.

Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.4049/jimmunol.1200057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969817PMC
May 2013