Leanne de Kock

Leanne de Kock

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Leanne de Kock

Leanne de Kock

Publications by authors named "Leanne de Kock"

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Further evidence that full gene deletions of DICER1 predispose to DICER1 syndrome.

Genes Chromosomes Cancer 2019 08 28;58(8):602-604. Epub 2019 Jan 28.

Department of Human Genetics, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1002/gcc.22728DOI Listing
August 2019

Ten years of DICER1 mutations: Provenance, distribution, and associated phenotypes.

Hum Mutat 2019 Jul 24. Epub 2019 Jul 24.

Department of Human Genetics, McGill University, Montréal, Québec, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/humu.23877
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http://dx.doi.org/10.1002/humu.23877DOI Listing
July 2019

An update on the central nervous system manifestations of DICER1 syndrome.

Acta Neuropathol 2019 Apr 5. Epub 2019 Apr 5.

Department of Pathology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Bader 104, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s00401-019-01997-yDOI Listing
April 2019

Infantile Pulmonary Teratoid Tumor.

N Engl J Med 2018 06;378(23):2238-2240

McGill University, Montreal, QC, Canada

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http://dx.doi.org/10.1056/NEJMc1803354DOI Listing
June 2018

DICER1 Mutations Are Frequent in Adolescent-Onset Papillary Thyroid Carcinoma.

J Clin Endocrinol Metab 2018 05;103(5):2009-2015

Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1210/jc.2017-02698DOI Listing
May 2018

Familial multinodular goiter and Sertoli-Leydig cell tumors associated with a large intragenic in-frame deletion.

Eur J Endocrinol 2018 Feb 29;178(2):K11-K19. Epub 2017 Nov 29.

Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montréal, Québec, Canada.

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http://dx.doi.org/10.1530/EJE-17-0904DOI Listing
February 2018

A case of neuroblastoma in DICER1 syndrome: Chance finding or noncanonical causation?

Pediatr Blood Cancer 2018 Jan 2;65(1). Epub 2017 Aug 2.

Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.

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http://dx.doi.org/10.1002/pbc.26715DOI Listing
January 2018

DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.

Am J Surg Pathol 2017 Sep;41(9):1178-1187

*Department of Human Genetics, McGill University †Segal Cancer Centre, Lady Davis Institute, Jewish General Hospital ¶Research Institute of the McGill University Health Centre, Montréal, QC, Canada ‡Department of Laboratory Medicine and Pathobiology, University Health Network, University of Toronto, Toronto, ON, Canada §Department of Pathology, Belfast Health and Social Care Trust, Royal Group of Hospitals Trust, Belfast, United Kingdom ∥School for Women's and Infants' Health, University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1097/PAS.0000000000000895DOI Listing
September 2017

Biologic and Clinical Perspectives on Thyroid Cancer.

N Engl J Med 2016 12;375(23):2306-2307

McGill University, Montreal, QC, Canada

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http://dx.doi.org/10.1056/NEJMc1613118DOI Listing
December 2016

Sarcoma and germ-line DICER1 mutations.

Lancet Oncol 2016 11;17(11):e470

Department of Human Genetics, McGill University, Montréal, Quebec, Canada; Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, 3755 Cote Sainte Catherine Road, Montreal, Quebec H3T 1E2, Canada; Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30522-8DOI Listing
November 2016

Deep Sequencing Reveals Spatially Distributed Distinct Hot Spot Mutations in DICER1-Related Multinodular Goiter.

J Clin Endocrinol Metab 2016 10 26;101(10):3637-3645. Epub 2016 Jul 26.

Departments of Human Genetics (L.d.K., M.K.W., W.D.F.), Pathology (I.B.), Oncology (W.D.F.), McGill University; Department of Medical Genetics, Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital (L.d.K., M.K.W., N.S., W.D.F.); Research Institute of the McGill University Health Centre (L.d.K., W.D.F.); McGill University and Genome Québec Innovation Centre (T.R., P.B., J.R.), Montréal, Québec, Canada; and (J.R.P.), Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1210/jc.2016-1328DOI Listing
October 2016

Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.

Int J Gynecol Pathol 2016 Jul;35(4):301-8

Department of Pathology (S.C., I.H., V.V.), Centre Regional de Lutte Contre Le Cancer, Bordeaux, France Department of Human Genetics (L.d.K., W.D.F.), McGill University Segal Cancer Centre (L.d.K., W.D.F.), Lady Davis Institute, Jewish General Hospital Department of Medical Genetics (T.B., W.D.F.), Research Institute of the McGill University Health Centre Program in Cancer Genetics (W.D.F.), Department of Oncology and Human Genetics, McGill University, Montreal, QC, Canada Department of Pathology (W.G.M.C.), Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.

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https://insights.ovid.com/crossref?an=00004347-201607000-000
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http://dx.doi.org/10.1097/PGP.0000000000000240DOI Listing
July 2016

Somatic DICER1 mutations in adult-onset pulmonary blastoma.

Eur Respir J 2016 06 28;47(6):1879-82. Epub 2016 Apr 28.

Dept of Human Genetics, McGill University, Montreal, QC, Canada Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada Dept of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, QC, Canada Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, QC, Canada

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http://dx.doi.org/10.1183/13993003.00172-2016DOI Listing
June 2016

Germline and Somatic DICER1 Mutations in a Well-Differentiated Fetal Adenocarcinoma of the Lung.

J Thorac Oncol 2016 Mar 10;11(3):e31-3. Epub 2015 Dec 10.

Department of Human Genetics, McGill University, Montreal, Quebec, Canada; Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Quebec, Canada; Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada; Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2015.09.012DOI Listing
March 2016

Adult-Onset Cervical Embryonal Rhabdomyosarcoma and DICER1 Mutations.

J Low Genit Tract Dis 2016 Jan;20(1):e8-e10

Department of Human Genetics McGill University Montreal, Quebec Canada Lady Davis Institute Segal Cancer Centre Jewish General Hospital Montreal, Quebec Canada Lady Davis Institute Segal Cancer Centre Jewish General Hospital Montreal, Quebec Canada Department of Gynecologic Oncology IRCCS National Cancer Institute Milan, Italy Department of Oncology Medical Center HCP Poznan, Poland Department of Pediatric Endocrinology and Rheumatology Poznan University of Medical Sciences Poznan, Poland Department of Human Genetics McGill University Montreal, Quebec Canada Lady Davis Institute Segal Cancer Centre Jewish General Hospital Montreal, Quebec Canada Department of Medical Genetics Research Institute of the McGill University Health Centre Montreal, Quebec Canada

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/LGT.0000000000000149DOI Listing
January 2016

High-sensitivity sequencing reveals multi-organ somatic mosaicism causing DICER1 syndrome.

J Med Genet 2016 Jan 16;53(1):43-52. Epub 2015 Oct 16.

Department of Human Genetics, McGill University, Montréal, Québec, Canada Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montréal, Québec, Canada Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1136/jmedgenet-2015-103428DOI Listing
January 2016

Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome.

Hum Pathol 2015 Jun 5;46(6):917-22. Epub 2015 Mar 5.

Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 0G4; Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2; Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada H3H 2R9; Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada H2W 1S6. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2015.02.008DOI Listing
June 2015

Exploring the association Between DICER1 mutations and differentiated thyroid carcinoma.

J Clin Endocrinol Metab 2014 Jun 11;99(6):E1072-7. Epub 2014 Mar 11.

Department of Human Genetics (L.d.K.) and Program in Cancer Genetics, Department of Oncology and Human Genetics (W.D.F.), McGill University, Montreal, Quebec H2W 1S6, Canada; Lady Davis Institute (L.d.K., N.S.), Segal Cancer Centre, Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada; Department of Pathology (D.B.-D.S., R.C.) and Endocrine Service (C.L.D.), CHU-Sainte Justine and University of Montreal, Montreal, Quebec H3T 1C5, Canada; Department of Pediatric Radiology (R.P.G.), Baylor College of Medicine, Texas Children's Hospital, Houston, Texas 77030; Center for Pediatric Oncology (B.-K.P.), National Cancer Center, Goyang-si, South Korea 410-769; and (J.R.P.) Minneapolis, Minnesota 55454.

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http://dx.doi.org/10.1210/jc.2013-4206DOI Listing
June 2014

DICER1 mutations in an adolescent with cervical embryonal rhabdomyosarcoma (cERMS).

Pediatr Blood Cancer 2014 Mar 22;61(3):568-9. Epub 2013 Oct 22.

Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.24826DOI Listing
March 2014

Germ-line and somatic DICER1 mutations in a pleuropulmonary blastoma.

Pediatr Blood Cancer 2013 Dec 19;60(12):2091-2. Epub 2013 Jul 19.

Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada.

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http://dx.doi.org/10.1002/pbc.24692DOI Listing
December 2013