Leanne E Felkin

Leanne E Felkin

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Leanne E Felkin

Leanne E Felkin

Publications by authors named "Leanne E Felkin"

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39Publications

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Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.

Circulation 2019 Sep 9;140(11):937-951. Epub 2019 Jul 9.

Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore (S.C., S.S., E.A., S.V., A.W., S.L., M.W., G.D., S.G.S., B.L.G., S.L., E.Y.C., E.C., J.D., S.A.C., O.J.L.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.039596DOI Listing
September 2019

The Translational Landscape of the Human Heart.

Cell 2019 Jun 30;178(1):242-260.e29. Epub 2019 May 30.

Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, 13347 Berlin, Germany; Berlin Institute of Health (BIH), 10178 Berlin, Germany; Charité-Universitätsmedizin, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.05.010DOI Listing
June 2019

The Calcineurin Variant CnAβ1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation.

Cell Chem Biol 2016 Nov 13;23(11):1372-1382. Epub 2016 Oct 13.

Myocardial Pathophysiology Program, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain; National Heart and Lung Institute, Imperial College London, London SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2016.09.010DOI Listing
November 2016

Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure.

J Am Heart Assoc 2014 Dec;3(6):e001104

Division of Cardiovascular Medicine, Department of Internal Medicine, Cardiovascular Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA

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http://dx.doi.org/10.1161/JAHA.114.001104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338699PMC
December 2014

Heat shock protein-27 delays acute rejection after cardiac transplantation: an experimental model.

Transplantation 2014 Jul;98(1):29-38

1 Transplant Immunology Group, National Heart and Lung Institute, Imperial College, Harefield Heart Science Centre, Harefield, United Kingdom. 2 Molecular Biology Group, National Heart and Lung Institute, Imperial College, Harefield Heart Science Centre, Harefield, United Kingdom. 3 Address correspondence to: Marlene Rose, Ph.D., National Heart and Lung Institute, Imperial College, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, UB9 6JH, UK.

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http://dx.doi.org/10.1097/TP.0000000000000170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164282PMC
July 2014

Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1.

J Cardiovasc Transl Res 2010 Dec 25;3(6):688-95. Epub 2010 Jun 25.

Heart Science Centre, National Heart and Lung Institute, Imperial College, Harefield, Middlesex, London, UK.

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http://dx.doi.org/10.1007/s12265-010-9199-1DOI Listing
December 2010

A gene expression profile of the myocardial response to clenbuterol.

J Cardiovasc Transl Res 2009 Jun 13;2(2):191-7. Epub 2009 Mar 13.

Harefield Heart Science Centre, National Heart and Lung Institute, Imperial College, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.

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http://link.springer.com/content/pdf/10.1007%2Fs12265-009-90
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http://link.springer.com/10.1007/s12265-009-9097-6
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http://dx.doi.org/10.1007/s12265-009-9097-6DOI Listing
June 2009

Expression of extracellular matrix genes during myocardial recovery from heart failure after left ventricular assist device support.

J Heart Lung Transplant 2009 Feb;28(2):117-22

Harefield Heart Science Centre, National Heart and Lung Institute, Imperial College London, Harefield, Middlesex, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S105324980801733
Publisher Site
http://dx.doi.org/10.1016/j.healun.2008.11.910DOI Listing
February 2009

Expression of follistatin-related genes is altered in heart failure.

Endocrinology 2008 Nov 10;149(11):5822-7. Epub 2008 Jul 10.

Harefield Heart Science Centre, Hill End Road, Harefield, Middlesex UB9 6JH, United Kingdom.

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http://dx.doi.org/10.1210/en.2008-0151DOI Listing
November 2008

Heterogeneic nature of adult cardiac side population cells.

Biochem Biophys Res Commun 2008 Jul 14;371(4):615-20. Epub 2008 Apr 14.

Harefield Heart Science Centre, Imperial College London, Middlesex, UK.

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http://dx.doi.org/10.1016/j.bbrc.2008.04.021DOI Listing
July 2008

Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure.

Cardiovasc Res 2008 Mar 4;77(4):695-706. Epub 2008 Jan 4.

Heart Science Centre, Imperial College London, National Heart and Lung Institute, Laboratory of Cellular Electrophysiology, Harefield Hospital, Harefield, Middlesex, UK.

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http://dx.doi.org/10.1093/cvr/cvm106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436743PMC
March 2008

Direct intramyocardial but not intracoronary injection of bone marrow cells induces ventricular arrhythmias in a rat chronic ischemic heart failure model.

Circulation 2007 May 16;115(17):2254-61. Epub 2007 Apr 16.

Harefield Heart Science Centre, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.662577DOI Listing
May 2007

Correlation between vascular responsivensss and expression of novel transcripts of the ETA-receptor in human vascular tissue.

Vascul Pharmacol 2007 Mar 18;46(3):181-7. Epub 2006 Oct 18.

Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, UB9 6JH, United Kingdom.

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http://dx.doi.org/10.1016/j.vph.2006.09.007DOI Listing
March 2007

Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy.

Eur Heart J 2007 Mar 28;28(5):613-27. Epub 2006 Nov 28.

Lillehei Heart Institute, Division of Cardiology, Department of Medicine, University of Minnesota, Mayo Mail Code 508, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1093/eurheartj/ehl365DOI Listing
March 2007

Real-time quantitative polymerase chain reaction in cardiac transplant research.

Methods Mol Biol 2006 ;333:305-30

National Heart and Lung Institute, Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, England.

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http://dx.doi.org/10.1385/1-59745-049-9:305DOI Listing
July 2006

Expression of human membrane skeleton protein genes for protein 4.1 and betaIISigma2-spectrin assayed by real-time RT-PCR.

Cell Mol Biol Lett 2005 ;10(1):135-49

Randall Division of Cell and Molecular Biophysics, King's College London, Guy's Campus, London SE1 1UL, UK.

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August 2005

Phenylephrine requires the TATA box to activate transcription of GLUT1 in neonatal rat cardiac myocytes.

J Mol Cell Cardiol 2005 Apr;38(4):677-84

National Heart and Lung Institute, Faculty of Medicine, Imperial College London, Heart Science Centre, Harefield, Middlesex, UK.

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http://dx.doi.org/10.1016/j.yjmcc.2005.02.013DOI Listing
April 2005

Sequential expression of three known protective genes in cardiac biopsies after transplantation.

Transplantation 2005 Mar;79(5):584-90

Department of Transplant Immunology, National Heart and Lung Institute, Imperial College London, Heart Science Centre, Harefield Hospital, Harefield, Middlesex, United Kingdom.

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http://dx.doi.org/10.1097/01.tp.0000153154.37616.94DOI Listing
March 2005

The slow skeletal muscle troponin T gene is expressed in developing and diseased human heart.

Mol Cell Biochem 2004 Aug;263(1):91-7

Department of Basic Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.

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http://dx.doi.org/10.1023/B:MCBI.0000041851.53074.72DOI Listing
August 2004

The slow skeletal muscle troponin T gene is expressed in developing and diseased human heart.

Mol Cell Biochem 2004 Aug;263(1-2):91-7

National Heart and Lung Institute, Imperial College, London, Heart Science Centre, Harefield, Middlesex UB9 6JH, UK.

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August 2004

Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices.

J Heart Lung Transplant 2004 Feb;23(2):228-35

Heart Science Centre, Royal Brompton and Harefield Hospital, Harefield, Middlesex, United Kingdom.

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http://dx.doi.org/10.1016/S1053-2498(03)00106-2DOI Listing
February 2004

Increased expression of extracellular matrix regulators TIMP1 and MMP1 in deteriorating heart failure.

J Heart Lung Transplant 2003 Jul;22(7):738-44

Heart Science Centre, Royal Brompton and Harefield Hospital, Harefield, Middlesex, United Kingdom

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http://dx.doi.org/10.1016/s1053-2498(02)00557-0DOI Listing
July 2003