Leandro Cerchietti

Leandro Cerchietti

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Leandro Cerchietti

Leandro Cerchietti

Publications by authors named "Leandro Cerchietti"

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79Publications

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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.

Cancer Cell 2019 Jun;35(6):916-931.e9

Department of Medicine, Division of Hematology & Medical Oncology, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.05.002DOI Listing
June 2019

Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells.

Oncotarget 2019 Apr 30;10(32):3051-3065. Epub 2019 Apr 30.

Instituto de Investigaciones Biomédicas (BIOMED), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Ciencias Médicas, Pontificia Universidad Católica Argentina (UCA), Buenos Aires, Argentina.

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http://dx.doi.org/10.18632/oncotarget.26890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508960PMC
April 2019

Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway.

EBioMedicine 2018 Feb 31;28:80-89. Epub 2018 Jan 31.

Hematology and Oncology Division, Weill Cornell Medicine, Cornell University, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835559PMC
February 2018

The eIF4E inhibitor ribavirin as a potential antilymphoma therapeutic: early clinical data.

Leuk Lymphoma 2018 01 2;59(1):256-258. Epub 2017 Jun 2.

a Department of Medicine, Division of Hematology and Oncology , Meyer Cancer Center, Weill Cornell Medicine and New York-Presbyterian Hospital , New York , NY , USA.

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http://dx.doi.org/10.1080/10428194.2017.1323270DOI Listing
January 2018

Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model.

Cancer Res 2017 04 27;77(8):1818-1830. Epub 2017 Jan 27.

Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392381PMC
April 2017

DNA Methylation-Based Biomarkers.

J Clin Oncol 2017 03 23;35(7):793-795. Epub 2017 Jan 23.

Leandro Cerchietti and Ari Melnick, Weill Cornell Medicine, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.0616DOI Listing
March 2017

Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients.

Clin Epigenetics 2016 22;8:79. Epub 2016 Jul 22.

Division of Hematology and Medical Oncology, Weill Cornell Medical College and New York Presbyterian Hospital, New York, NY 10065 USA.

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http://dx.doi.org/10.1186/s13148-016-0245-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957280PMC
December 2016

Therapeutic implication of concomitant chromosomal aberrations in patients with aggressive B-cell lymphomas.

Cell Cycle 2016 Sep 15;15(17):2241-7. Epub 2016 Jul 15.

a Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine , New York , NY , USA.

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http://dx.doi.org/10.1080/15384101.2016.1207839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004704PMC
September 2016

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells.

Biomaterials 2015 Dec 11;73:110-9. Epub 2015 Sep 11.

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623826PMC
December 2015

Ex vivo engineered immune organoids for controlled germinal center reactions.

Biomaterials 2015 Sep 3;63:24-34. Epub 2015 Jun 3.

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490011PMC
September 2015

Epigenomic evolution in diffuse large B-cell lymphomas.

Nat Commun 2015 Apr 20;6:6921. Epub 2015 Apr 20.

1] Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA [2] Institute for Precision Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/ncomms7921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411286PMC
April 2015

Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells.

Blood 2015 Jan 8;125(5):841-51. Epub 2014 Dec 8.

Neuroimmunomodulation and Molecular Oncology Department, Institute for Biomedical Research (BIOMED), National Research Council of Argentina (CONICET), Catholic University of Argentina (UCA), Buenos Aires, Argentina; Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1182/blood-2014-07-587337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311229PMC
January 2015

Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications.

Cell Mol Bioeng 2014 Sep;7(3):394-408

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1007/s12195-014-0353-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196273PMC
September 2014

Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.

ACS Chem Biol 2014 Aug 17;9(8):1698-705. Epub 2014 Jun 17.

Program in Molecular Pharmacology and Chemistry and Department of Medicine and §Program in Molecular Biology, Proteomics Core, Memorial Sloan-Kettering Cancer Center , New York, New York 10021, United States.

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http://dx.doi.org/10.1021/cb500256uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134716PMC
August 2014

Targeting the epigenome and other new strategies in diffuse large B-cell lymphoma: beyond R-CHOP.

Hematology Am Soc Hematol Educ Program 2013 ;2013:591-5

1Division of Hematology and Medical Oncology, Weill Cornell Medical College and New York Presbyterian Hospital, New York, NY.

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http://dx.doi.org/10.1182/asheducation-2013.1.591DOI Listing
July 2014

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

Nature 2014 Jul 28;511(7507):90-3. Epub 2014 May 28.

Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, Université de Montréal, P.O. Box 6128, Downtown Station, Montréal, Québec H3C 3J7, Canada.

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http://dx.doi.org/10.1038/nature13283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138053PMC
July 2014

Mir-592 regulates the induction and cell death-promoting activity of p75NTR in neuronal ischemic injury.

J Neurosci 2014 Feb;34(9):3419-28

Department of Medicine and Brain and Mind Research Institute, Weill Cornell Medical College, New York, New York 10065, and Interdisciplinary Center for Neurosciences, Department of Neuroanatomy, University of Heidelberg, INF 307, D69120 Heidelberg, Germany.

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http://www.jneurosci.org/content/34/9/3419.full.pdf
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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1982-13.2
Publisher Site
http://dx.doi.org/10.1523/JNEUROSCI.1982-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935094PMC
February 2014

Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.

Cancer Discov 2013 Sep 16;3(9):1002-19. Epub 2013 Aug 16.

1Division of Hematology and Oncology, Department of Medicine, 2Division of Biostatistics and Epidemiology, Department of Public Health, 3Weill Cornell Cancer Center, and Departments of 4Pathology and 5Pharmacology, Weill Cornell Medical College, Cornell University, New York, New York; 6Section of Hematology/Oncology, Department of Medicine, The University of Chicago; Department of Pathology, Northwestern University, Chicago, Illinois; 8Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, University of Montreal, Montreal, Quebec; 9Centre for Lymphoid Cancer, BC Cancer Agency, Vancouver, British Columbia, Canada; 10IBM Research, Rio de Janeiro, Brazil; and 11Department of Oncological Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770813PMC
September 2013

The metabolism of lymphomas.

Curr Opin Hematol 2013 Jul;20(4):345-54

Hematology and Oncology Division, Medicine Department, Weill Cornell Medical College of Cornell University, New York, New York 10065, USA.

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http://dx.doi.org/10.1097/MOH.0b013e3283623d16DOI Listing
July 2013

Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes.

Blood 2013 Jun 30;121(26):5192-202. Epub 2013 Apr 30.

Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-03-49
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http://dx.doi.org/10.1182/blood-2013-03-490763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695363PMC
June 2013

BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.

J Clin Invest 2010 Dec 1;120(12):4569-82. Epub 2010 Nov 1.

Hematology and Oncology Division, and Department of Pharmacology, Weill Cornell Medical College, New York, New York, USA. Department of Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, New York, New York, USA. Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada. Department of Pathology, Weill Cornell Medical College, New York, New York, USA. Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. The University of Kansas Cancer Center, Kansas University Medical Center, Kansas City, Kansas, USA. Centre for Lymphoid Cancers and the Departments of Pathology and Experimental Therapeutics, British Columbia Cancer Agency, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1172/JCI42869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993589PMC
December 2010

DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma.

Blood 2010 Nov 7;116(20):e81-9. Epub 2010 Jul 7.

Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1182/blood-2010-05-285320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993635PMC
November 2010

Morphine versus midazolam as upfront therapy to control dyspnea perception in cancer patients while its underlying cause is sought or treated.

J Pain Symptom Manage 2010 May;39(5):820-30

Internal Medicine Department, Instituto Angel H. Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jpainsymman.2009.10.003DOI Listing
May 2010

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.

Blood 2009 Apr 16;113(15):3397-405. Epub 2008 Oct 16.

Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell College of Medicine, New York, NY 10065, USA

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http://dx.doi.org/10.1182/blood-2008-07-168773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668844PMC
April 2009

Sequential transcription factor targeting for diffuse large B-cell lymphomas.

Cancer Res 2008 May;68(9):3361-9

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748725PMC
May 2008

Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.

Mol Cell 2008 Feb;29(3):384-91

Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, 101 College Street, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.molcel.2007.12.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665293PMC
February 2008

Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer.

Nutr Cancer 2007 ;59(1):14-20

Translational Research Unit, Angel H Roffo Cancer Institute, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1080/01635580701365068DOI Listing
January 2008

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

Proc Natl Acad Sci U S A 2007 Feb 20;104(9):3207-12. Epub 2007 Feb 20.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0611399104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805543PMC
February 2007

Morphine mouthwashes for painful mucositis.

Support Care Cancer 2007 Jan 15;15(1):115-6; author reply 117. Epub 2006 Aug 15.

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http://link.springer.com/10.1007/s00520-006-0124-8
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http://dx.doi.org/10.1007/s00520-006-0124-8DOI Listing
January 2007

Inhibition of tumor progression and paraneoplastic syndrome development in a murine lung adenocarcinoma by medroxyprogesterone acetate and indomethacin.

Cancer Invest 2006 Mar;24(2):126-31

Animal Care and Experimental Cancer Department, Angel H. Roffo Institute of Oncology, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1080/07357900500524322DOI Listing
March 2006

Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer.

J Pain Symptom Manage 2006 Jan;31(1):38-47

Internal Medicine Department and Translational Research Unit, Angel H. Roffo Cancer Institute, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jpainsymman.2005.06.009DOI Listing
January 2006

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

Nat Med 2004 Dec 7;10(12):1329-35. Epub 2004 Nov 7.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nm1134DOI Listing
December 2004

Effects of celecoxib, medroxyprogesterone, and dietary intervention on systemic syndromes in patients with advanced lung adenocarcinoma: a pilot study.

J Pain Symptom Manage 2004 Jan;27(1):85-95

Supportive Care Division, Angel H. Roffo Cancer Institute, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.jpainsymman.2003.05.010DOI Listing
January 2004

Potential utility of the peripheral analgesic properties of morphine in stomatitis-related pain: a pilot study.

Pain 2003 Sep;105(1-2):265-73

Translational Research Unit, Angel H Roffo Cancer Institute, University of Buenos Aires, Ecuador 1573 1p 3, 1425, Buenos Aires, Argentina.

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http://pdfs.journals.lww.com/pain/2003/09000/Potential_utili
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http://dx.doi.org/10.1016/s0304-3959(03)00227-6DOI Listing
September 2003

Effect of topical morphine for mucositis-associated pain following concomitant chemoradiotherapy for head and neck carcinoma.

Cancer 2002 Nov;95(10):2230-6

Supportive Care Division, Department of Medical Oncology, Angel H. Roffo Cancer Institute, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1002/cncr.10938DOI Listing
November 2002