Lea Davis

Lea Davis

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Sex differences in the genetic architecture of obsessive-compulsive disorder.

Am J Med Genet B Neuropsychiatr Genet 2019 Sep 20;180(6):351-364. Epub 2018 Nov 20.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois.

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http://doi.wiley.com/10.1002/ajmg.b.32687
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http://dx.doi.org/10.1002/ajmg.b.32687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527502PMC
September 2019

The new science of sex differences in neuropsychiatric traits.

Am J Med Genet B Neuropsychiatr Genet 2019 Sep 24;180(6):333-334. Epub 2019 Jun 24.

Section of Genetic Medicine, Department of Medicine, The University of Chicago.

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http://dx.doi.org/10.1002/ajmg.b.32747DOI Listing
September 2019

Estimating Uterine Fibroid SNP-Based Heritability in European American Women with Imaging-Confirmed Fibroids.

Hum Hered 2019 Sep 3:1-9. Epub 2019 Sep 3.

Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA,

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http://dx.doi.org/10.1159/000501335DOI Listing
September 2019

Author Correction: The role of sex in the genomics of human complex traits.

Nat Rev Genet 2019 Aug;20(8):494

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41576-019-0148-9DOI Listing
August 2019

Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems.

Am J Psychiatry 2019 Aug 16:appiajp201918091085. Epub 2019 Aug 16.

Psychiatric and Neurodevelopmental Genetics Unit (Zheutlin, Chen, Ge, Smoller) and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (Chen); Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Mass. (Zheutlin, Chen, Stahl, Smoller); Division of Genetic Medicine, Department of Medicine (Dennis, Straub, Ruderfer, Davis), Vanderbilt Genetics Institute (Dennis, Straub, Ruderfer, Davis), and Department of Biomedical Informatics (Ruderfer), Vanderbilt University Medical Center, Nashville; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam (Karlsson Linnér); Autism and Developmental Medicine Institute, Geisinger, Lewisburg, Pa. (Karlsson Linnér, Chabris); Charles Bronfman Institute for Personalized Medicine (Moscati), Pamela Sklar Division of Psychiatric Genomics (Huckins, Charney, Stahl), and Department of Genetics and Genomic Sciences (Huckins, Charney, Stahl, ), Icahn School of Medicine at Mount Sinai, New York; Department of Biomedical and Translational Informatics, Geisinger, Rockville, Md. (Restrepo, Kirchner); Research Information Science and Computing, Partners HealthCare, Somerville, Mass. (Castro).

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http://dx.doi.org/10.1176/appi.ajp.2019.18091085DOI Listing
August 2019

Usefulness of Single Nucleotide Polymorphisms as Predictors of Sudden Cardiac Death.

Am J Cardiol 2019 Jun 20;123(12):1900-1905. Epub 2019 Mar 20.

Division of Cardiology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, Florida.

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http://dx.doi.org/10.1016/j.amjcard.2019.02.058DOI Listing
June 2019

The role of sex in the genomics of human complex traits.

Nat Rev Genet 2019 03;20(3):173-190

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41576-018-0083-1
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http://dx.doi.org/10.1038/s41576-018-0083-1DOI Listing
March 2019

Common knowledge: shared genetics in psychiatry.

Nat Neurosci 2019 03;22(3):331-332

Department of Medicine, Department of Psychiatry and Behavioral Sciences, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1038/s41593-019-0346-yDOI Listing
March 2019

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

Am J Psychiatry 2019 Mar;176(3):217-227

The Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston (Yu, Illmann, Osiecki, Smoller, Pauls, Neale, Scharf); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass. (Yu, Neale, Scharf); the Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles (Sul, Huang, Zelaya, Ophoff, Freimer, Coppola); the Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (Sul, Huang, Zelaya, Freimer, Coppola); the Department of Molecular Biology and Genetics, Democritus University of Thrace, Xanthi, Greece (Tsetsos); the Department of Biological Sciences, Purdue University, West Lafayette, Ind. (Tsetsos, Paschou); deCODE Genetics/Amgen, Reykjavik, Iceland (Nawaz, H. Stefansson, K. Stefansson); the Bioinformatics Interdepartmental Program, University of California, Los Angeles (Huang, Zelaya); the Department of Psychiatry, University of California, San Francisco (Darrow); the Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco (Hirschtritt, Willsey); the Department of Psychiatry, Massachusetts General Hospital, Boston (Greenberg, Roffman, Buckner); the Clinic of Psychiatry, Social Psychiatry, and Psychotherapy, Hannover Medical School, Hannover, Germany (Muller-Vahl); the Institute of Human Genetics, Hannover Medical School, Hannover, Germany (Stuhrmann); McGill University Health Center, University of Montreal, McGill University Health Centre, Montreal (Dion); the Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal (Rouleau); the Department of Psychiatry and Psychotherapy, Medical University Vienna, Vienna (Aschauer, Stamenkovic); Biopsychosocial Corporation, Vienna (Aschauer, Schlögelhofer); University Health Network, Youthdale Treatment Centres, and University of Toronto, Toronto (Sandor); the Krembil Research Institute, University Health Network, Hospital for Sick Children, and University of Toronto, Toronto (Barr); Johns Hopkins University School of Medicine, Baltimore (Grados, Singer); the Institute of Human Genetics, University Hospital Bonn, University of Bonn Medical School, Bonn, Germany (Nöthen); the Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany (Hebebrand, Hinney); the Yale Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (King, Fernandez); the Institute of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest, Hungary (Barta); Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary (Tarnok, Nagy); the Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen, Essen, Germany (Depienne); Sorbonne Universités, UPMC Université Paris 06, UMR S 1127, CNRS UMR 7225, ICM, Paris (Depienne, Worbe, Hartmann); French Reference Centre for Gilles de la Tourette Syndrome, Groupe Hospitalier Pitié-Salpêtrière, Paris (Worbe, Hartmann); Assistance Publique-Hôpitaux de Paris, Department of Neurology, Groupe Hospitalier Pitié-Salpêtrière, Paris (Worbe, Hartmann); Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York (Budman); Child Neuropsychiatry, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy (Rizzo); the Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (Lyon); the Department of Psychiatry, University of Utah, Salt Lake City (McMahon); Children's Mercy Hospital, Kansas City, Mo. (Batterson); the Department of Psychiatry, University Medical Center Groningen and Rijksuniversity Groningen, and Drenthe Mental Health Center, Groningen, the Netherlands (Cath); the Department of Neurology, Fixel Center for Neurological Diseases, McKnight Brain Institute, University of Florida, Gainesville (Malaty, Okun); Pennsylvania State University College of Medicine, Hershey (Berlin); Marquette University and University of Wisconsin-Milwaukee, Milwaukee (Woods); Tripler Army Medical Center and University of Hawaii John A. Burns School of Medicine, Honolulu (Lee); Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston (Jankovic); the Division of Psychiatry, Department of Neuropsychiatry, University College London (Robertson); the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati (Gilbert); Children's Hospital of Philadelphia, Philadelphia (Brown); the Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami (Coffey); the Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (Dietrich, Hoekstra); University of Iowa Carver College of Medicine, Iowa City (Kuperman); the Department of Pediatrics, University of Washington, Seattle (Zinner); the Department of Pediatrics, Landspitalinn University Hospital, Reykjavik, Iceland (Luðvigsson, Thorarensen); the Faculty of Medicine, University of Iceland, Reykjavík, Iceland (Sæmundsen, Stefansson); the State Diagnostic and Counselling Centre, Kópavogur, Iceland (Sæmundsen); the Department of Genetics and the Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Atzmon, Barzilai); the Department of Human Biology, Haifa University, Haifa, Israel (Atzmon); the Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany (Wagner); the Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany (Moessner); SUNY Downstate Medical Center Brooklyn, New York (C.M. Pato, M.T. Pato, Knowles); the Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital, Charlestown (Roffman, Buckner); the Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston (Smoller); the Center for Brain Science and Department of Psychology, Harvard University, Cambridge, Mass. (Buckner); the Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco (Willsey); the Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway (Tischfield, Heiman); the Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, VU University Amsterdam, Amsterdam (Posthuma); the Division of Genetic Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tenn. (Cox, Davis); the Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston (Neale); the Department of Psychiatry, Genetics Institute, University of Florida, Gainesville (Mathews); and the Department of Neurology, Brigham and Women's Hospital, and the Department of Neurology, Massachusetts General Hospital, Boston (Scharf).

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http://dx.doi.org/10.1176/appi.ajp.2018.18070857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677250PMC
March 2019

Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry.

Addict Biol 2019 Jan 23;24(1):121-131. Epub 2017 Oct 23.

Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1111/adb.12574DOI Listing
January 2019

Bridging Molecular Genetics and Epidemiology to Better Understand Sex Differences in Attention-Deficit/Hyperactivity Disorder.

Biol Psychiatry 2018 06;83(12):e55-e57

Department of Medicine, Division of Genetic Medicine, Department of Psychiatry and Behavioral Sciences, and the Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.04.005DOI Listing
June 2018

Shared Genetic Control of Brain Activity During Sleep and Insulin Secretion: A Laboratory-Based Family Study.

Diabetes 2018 01 30;67(1):155-164. Epub 2017 Oct 30.

Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN

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http://dx.doi.org/10.2337/db16-1229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741150PMC
January 2018

Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.

Am J Psychiatry 2017 04 4;174(4):387-396. Epub 2016 Nov 4.

From the Department of Psychiatry, University of California, San Francisco; the Department of Medicine, Vanderbilt University Medical Center, Nashville; the Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; the Department of Psychiatry and University Health Network, University of Toronto, Toronto; the Youthdale Treatment Centres, Toronto; the Department of Psychiatry, University of Montreal, Montreal; the Yale Child Study Center and the Department of Genetics, Yale University School of Medicine, New Haven, Conn.; the Feinstein Institute for Medical Research, North Shore/Long Island Jewish Health System, Manhasset, N.Y.; the Faculty of Social and Behavioral Sciences, Utrecht University, Utrecht, The Netherlands; the Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.; the Department of Psychology, University of Denver, Denver; the Department of Psychiatry, University of Utah, Salt Lake City; the Department of Behavioral Health, Tripler Army Medical Center, Honolulu; the Departments of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Boston; and the Department of Psychiatry, University of Florida, Gainesville.

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http://dx.doi.org/10.1176/appi.ajp.2016.16020240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378637PMC
April 2017

Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation.

Neuropsychopharmacology 2017 Mar 15;42(4):811-821. Epub 2016 Sep 15.

Department of Human Genetics, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/npp.2016.197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312064PMC
March 2017

STAMS: STRING-assisted module search for genome wide association studies and application to autism.

Bioinformatics 2016 12 19;32(24):3815-3822. Epub 2016 Aug 19.

Departments of Bioengineering and Genetics, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167061PMC
December 2016

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Authors:
Dongmei Yu Carol A Mathews Jeremiah M Scharf Benjamin M Neale Lea K Davis Eric R Gamazon Eske M Derks Patrick Evans Christopher K Edlund Jacquelyn Crane Jesen A Fagerness Lisa Osiecki Patience Gallagher Gloria Gerber Stephen Haddad Cornelia Illmann Lauren M McGrath Catherine Mayerfeld Sampath Arepalli Cristina Barlassina Cathy L Barr Laura Bellodi Fortu Benarroch Gabriel Bedoya Berrió O Joseph Bienvenu Donald W Black Michael H Bloch Helena Brentani Ruth D Bruun Cathy L Budman Beatriz Camarena Desmond D Campbell Carolina Cappi Julio C Cardona Silgado Maria C Cavallini Denise A Chavira Sylvain Chouinard Edwin H Cook M R Cookson Vladimir Coric Bernadette Cullen Daniele Cusi Richard Delorme Damiaan Denys Yves Dion Valsama Eapen Karin Egberts Peter Falkai Thomas Fernandez Eduardo Fournier Helena Garrido Daniel Geller Donald L Gilbert Simon L Girard Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Edna Grünblatt John Hardy Gary A Heiman Sian M J Hemmings Luis D Herrera Dianne M Hezel Pieter J Hoekstra Joseph Jankovic James L Kennedy Robert A King Anuar I Konkashbaev Barbara Kremeyer Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Chunyu Liu Christine Lochner Thomas L Lowe Sara Lupoli Fabio Macciardi Wolfgang Maier Paolo Manunta Maurizio Marconi James T McCracken Sandra C Mesa Restrepo Rainald Moessner Priya Moorjani Jubel Morgan Heike Muller Dennis L Murphy Allan L Naarden Erika Nurmi William Cornejo Ochoa Roel A Ophoff Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Scott L Rauch Tobias Renner Victor I Reus Margaret A Richter Mark A Riddle Mary M Robertson Roxana Romero Maria C Rosário David Rosenberg Stephan Ruhrmann Chiara Sabatti Erika Salvi Aline S Sampaio Jack Samuels Paul Sandor Susan K Service Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein Eric Strengman Jay A Tischfield Maurizio Turiel Ana V Valencia Duarte Homero Vallada Jeremy Veenstra-VanderWeele Susanne Walitza Ying Wang Mike Weale Robert Weiss Jens R Wendland Herman G M Westenberg Yin Yao Shugart Ana G Hounie Euripedes C Miguel Humberto Nicolini Michael Wagner Andres Ruiz-Linares Danielle C Cath William McMahon Danielle Posthuma Ben A Oostra Gerald Nestadt Guy A Rouleau Shaun Purcell Michael A Jenike Peter Heutink Gregory L Hanna David V Conti Paul D Arnold Nelson B Freimer S Evelyn Stewart James A Knowles Nancy J Cox David L Pauls

Am J Psychiatry 2015 Jan 31;172(1):82-93. Epub 2014 Oct 31.

From the Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston; the Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Mass.; the Department of Psychiatry, University of California, San Francisco; the Department of Neurology, Massachusetts General Hospital, Boston; the Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston; the Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago; the Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam; the Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles; the Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Md.; the Genomic and Bioinformatic Unit, Filarete Foundation, Milan, Italy; the Department of Health Sciences, Graduate School of Nephrology, University of Milan, Milan; the Toronto Western Research Institute, University Health Network, Toronto; Hospital for Sick Children, Toronto; Università Vita-Salute San Raffaele, Milan; the Herman Dana Division of Child and Adolescent Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem; Universidad de Antioquia, Universidad Pontificia Bolivariana, Medellín, Colombia; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; the Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; the Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.; the Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil; North Shore-Long Island Jewish Medical Center and North Shore-Lo

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http://dx.doi.org/10.1176/appi.ajp.2014.13101306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282594PMC
January 2015

Consensus Genotyper for Exome Sequencing (CGES): improving the quality of exome variant genotypes.

Bioinformatics 2015 Jan 29;31(2):187-93. Epub 2014 Sep 29.

Department of Medicine, Section of Genetic Medicine, Computation Institute, University of Chicago, Chicago, IL 60637, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA, Vanderbilt Brain Institute, Vanderbilt University School of Medicine, Nashville, TN 37232 and Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60608, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287941PMC
January 2015

Structural architecture of SNP effects on complex traits.

Am J Hum Genet 2014 Nov 9;95(5):477-89. Epub 2014 Oct 9.

Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225594PMC
November 2014

Summaries of oral sessions at the XXI World Congress of Psychiatric Genetics, Boston, Massachusetts, 17-21 October 2013: state of the field.

Psychiatr Genet 2014 Aug;24(4):125-50

aMeharry Medical College, Nashville, Tennessee bHuman Genetics Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland cSection of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois dWashington University School of Medicine at Washington University Medical Center, St Louis, Missouri eHarvard Medical School, VA Boston Healthcare System, Brockton, Massachusetts fHospital for Sick Children, Toronto, Ontario, USA gDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan hThe Weizmann Institute of Science, Rehovot, Israel iMax-Planck Institute of Psychiatry, Munich jSection on Psychiatric Genetics, University Medical Center, University of Goettingen, Goettingen kDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany lDepartment of Psychiatry, Yuli Mental Health Research Center, Yuli Branch, Taipei Veterans General Hospital, Yuli mInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan nInstitute of Psychiatry, Department of Biomedical and Neuromotor Science - DIBINEM, University of Bologna, Bologna, Italy oDepartment of General Biology, Fluminense Federal University, Rio de Janeiro, Brazil pMRC Centre for Neuropsychiatric Genetics and Genomic, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff qMedical Research Council Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics rThe Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK sDepartment of Psychiatry and Neuropsychiatric Genetics Research Group, Trinity College Dublin, Trinity Centre for Health Sciences, St James's Hospital, Dublin, Ireland tNeurosciences, Molecular Genetics Laboratory, Neurobiology Research Center, National Institute of Mental Health and Neurosciences uNe

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http://dx.doi.org/10.1097/YPG.0000000000000043DOI Listing
August 2014

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.

Authors:
Lauren M McGrath Dongmei Yu Christian Marshall Lea K Davis Bhooma Thiruvahindrapuram Bingbin Li Carolina Cappi Gloria Gerber Aaron Wolf Frederick A Schroeder Lisa Osiecki Colm O'Dushlaine Andrew Kirby Cornelia Illmann Stephen Haddad Patience Gallagher Jesen A Fagerness Cathy L Barr Laura Bellodi Fortu Benarroch O Joseph Bienvenu Donald W Black Michael H Bloch Ruth D Bruun Cathy L Budman Beatriz Camarena Danielle C Cath Maria C Cavallini Sylvain Chouinard Vladimir Coric Bernadette Cullen Richard Delorme Damiaan Denys Eske M Derks Yves Dion Maria C Rosário Valsama Eapen Patrick Evans Peter Falkai Thomas V Fernandez Helena Garrido Daniel Geller Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Edna Grünblatt Gary A Heiman Sian M J Hemmings Luis D Herrera Ana G Hounie Joseph Jankovic James L Kennedy Robert A King Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Christine Lochner Thomas L Lowe Gholson J Lyon Fabio Macciardi Wolfgang Maier James T McCracken William McMahon Dennis L Murphy Allan L Naarden Benjamin M Neale Erika Nurmi Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Victor I Reus Margaret A Richter Mark Riddle Mary M Robertson David Rosenberg Guy A Rouleau Stephan Ruhrmann Aline S Sampaio Jack Samuels Paul Sandor Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein Jay A Tischfield Homero Vallada Jeremy Veenstra-VanderWeele Susanne Walitza Ying Wang Jens R Wendland Yin Yao Shugart Euripedes C Miguel Humberto Nicolini Ben A Oostra Rainald Moessner Michael Wagner Andres Ruiz-Linares Peter Heutink Gerald Nestadt Nelson Freimer Tracey Petryshen Danielle Posthuma Michael A Jenike Nancy J Cox Gregory L Hanna Helena Brentani Stephen W Scherer Paul D Arnold S Evelyn Stewart Carol A Mathews James A Knowles Edwin H Cook David L Pauls Kai Wang Jeremiah M Scharf

J Am Acad Child Adolesc Psychiatry 2014 Aug 24;53(8):910-9. Epub 2014 Jun 24.

Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address:

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http://dx.doi.org/10.1016/j.jaac.2014.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218748PMC
August 2014

Testing for association of the monoamine oxidase A promoter polymorphism with brain structure volumes in both autism and the fragile X syndrome.

J Neurodev Disord 2014 Mar 26;6(1). Epub 2014 Mar 26.

Department of Psychiatry, University of Iowa Carver College of Medicine, 1-191 MEB, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1186/1866-1955-6-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987046PMC
March 2014

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.

Authors:
Lea K Davis Dongmei Yu Clare L Keenan Eric R Gamazon Anuar I Konkashbaev Eske M Derks Benjamin M Neale Jian Yang S Hong Lee Patrick Evans Cathy L Barr Laura Bellodi Fortu Benarroch Gabriel Bedoya Berrio Oscar J Bienvenu Michael H Bloch Rianne M Blom Ruth D Bruun Cathy L Budman Beatriz Camarena Desmond Campbell Carolina Cappi Julio C Cardona Silgado Danielle C Cath Maria C Cavallini Denise A Chavira Sylvain Chouinard David V Conti Edwin H Cook Vladimir Coric Bernadette A Cullen Dieter Deforce Richard Delorme Yves Dion Christopher K Edlund Karin Egberts Peter Falkai Thomas V Fernandez Patience J Gallagher Helena Garrido Daniel Geller Simon L Girard Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Stephen Haddad Gary A Heiman Sian M J Hemmings Ana G Hounie Cornelia Illmann Joseph Jankovic Michael A Jenike James L Kennedy Robert A King Barbara Kremeyer Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Chunyu Liu Christine Lochner Thomas L Lowe Fabio Macciardi James T McCracken Lauren M McGrath Sandra C Mesa Restrepo Rainald Moessner Jubel Morgan Heike Muller Dennis L Murphy Allan L Naarden William Cornejo Ochoa Roel A Ophoff Lisa Osiecki Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Scott L Rauch Tobias J Renner Victor I Reus Margaret A Richter Mark A Riddle Mary M Robertson Roxana Romero Maria C Rosàrio David Rosenberg Guy A Rouleau Stephan Ruhrmann Andres Ruiz-Linares Aline S Sampaio Jack Samuels Paul Sandor Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein E Strengman Jay A Tischfield Ana V Valencia Duarte Homero Vallada Filip Van Nieuwerburgh Jeremy Veenstra-Vanderweele Susanne Walitza Ying Wang Jens R Wendland Herman G M Westenberg Yin Yao Shugart Euripedes C Miguel William McMahon Michael Wagner Humberto Nicolini Danielle Posthuma Gregory L Hanna Peter Heutink Damiaan Denys Paul D Arnold Ben A Oostra Gerald Nestadt Nelson B Freimer David L Pauls Naomi R Wray S Evelyn Stewart Carol A Mathews James A Knowles Nancy J Cox Jeremiah M Scharf

PLoS Genet 2013 Oct 24;9(10):e1003864. Epub 2013 Oct 24.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812053PMC
October 2013

Copy number variations on chromosome 12q14 in patients with normal tension glaucoma.

Hum Mol Genet 2011 Jun 29;20(12):2482-94. Epub 2011 Mar 29.

Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1093/hmg/ddr123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098731PMC
June 2011

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism.

Neuron 2011 Jun;70(5):863-85

Program on Neurogenetics, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.neuron.2011.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939065PMC
June 2011

Parent-of-origin effects of the serotonin transporter gene associated with autism.

Am J Med Genet B Neuropsychiatr Genet 2011 Mar 8;156(2):139-44. Epub 2010 Dec 8.

Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, 86 Jonathon Lucas St., Charleston, SC 29425, USA.

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http://doi.wiley.com/10.1002/ajmg.b.31146
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http://dx.doi.org/10.1002/ajmg.b.31146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438509PMC
March 2011

A single-tube quantitative high-resolution melting curve method for parent-of-origin determination of 15q duplications.

Genet Test Mol Biomarkers 2010 Aug;14(4):571-6

Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://www.liebertpub.com/doi/10.1089/gtmb.2010.0030
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http://dx.doi.org/10.1089/gtmb.2010.0030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064527PMC
August 2010

Cortical enlargement in autism is associated with a functional VNTR in the monoamine oxidase A gene.

Am J Med Genet B Neuropsychiatr Genet 2008 Oct;147B(7):1145-51

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1002/ajmg.b.30738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752707PMC
October 2008