Publications by authors named "Lazzaro Mazzoni"

11Publications

Identification with MRI of the pleura as a major site of the acute inflammatory effects induced by ovalbumin and endotoxin challenge in the airways of the rat.

Authors:
Harry Karmouty Quintana Catherine Cannet Elisabeth Schaeublin Stefan Zurbruegg Rosemary Sugar Lazzaro Mazzoni Clive P Page John R Fozard Nicolau Beckmann

Am J Physiol Lung Cell Mol Physiol 2006 Oct 25;291(4):L651-7. Epub 2006 May 25.

Novartis Institutes for BioMedical Research, Discovery Technologies, Lichtstr. 35, WSJ-386.2.09, CH-4002 Basel, Switzerland.

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October 2006

A locally active antiinflammatory macrolide (MLD987) for inhalation therapy of asthma.

Authors:
Rene Hersperger Karl-Heinz Buchheit Salvatore Cammisuli Albert Enz Olivier Lohse Monique Ponelle Walter Schuler Alain Schweitzer Christoph Walker Hartmut Zehender Gerhard Zenke Alfred G Zimmerlin Markus Zollinger Lazzaro Mazzoni John R Fozard

J Med Chem 2004 Sep;47(20):4950-7

Novartis Institutes for BioMedical Research and Novartis Pharma Development, CH-4002 Basle, Switzerland.

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September 2004

Synthesis and biological properties of novel glucocorticoid androstene C-17 furoate esters.

Authors:
David A Sandham Lucy Barker David Beattie David Beer Louise Bidlake David Bentley Keith D Butler Sarah Craig David Farr Claire Ffoulkes-Jones John R Fozard Sandra Haberthuer Colin Howes Deborah Hynx Sarah Jeffers Thomas H Keller Paul A Kirkham Janet C Maas Lazzaro Mazzoni Andrew Nicholls Gaynor E Pilgrim Elisabeth Schaebulin Gillian M Spooner Rowan Stringer Pamela Tranter Katharine L Turner Morris F Tweed Christoph Walker Simon J Watson Bernard M Cuenoud

Bioorg Med Chem 2004 Oct;12(19):5213-24

Novartis Institutes for Biomedical Research, Horsham Research Centre, Wimblehurst Road, Horsham, West Sussex, RH12 5AB, United Kingdom.

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October 2004

New highly potent and selective adenosine A(3) receptor antagonists.

Authors:
Neil J Press Thomas H Keller Pamela Tranter David Beer Ken Jones Alexander Faessler Richard Heng Christine Lewis Trevor Howe Peter Gedeck Lazzaro Mazzoni John R Fozard

Curr Top Med Chem 2004 ;4(8):863-70

Respiratory Disease Area, Novartis Horsham Research Center, Wimblehurst Road, Horsham, West Sussex, RH12 5AB, UK.

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October 2004

Techniques: magnetic resonance imaging of the lung provides potential for non-invasive preclinical evaluation of drugs.

Authors:
Nicolau Beckmann Bruno Tigani Lazzaro Mazzoni John R Fozard

Trends Pharmacol Sci 2003 Oct;24(10):550-4

Discovery Technologies Center, Novartis Institutes for BioMedical Research, Lichtstrasse 35, WSJ-386.2.09, CH-4002 Basel, Switzerland.

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October 2003

Resolution of the oedema associated with allergic pulmonary inflammation in rats assessed noninvasively by magnetic resonance imaging.

Authors:
Bruno Tigani Catherine Cannet Stefen Zurbrugg Elisabeth Schaeublin Lazzaro Mazzoni John R Fozard Nicolau Beckmann

Br J Pharmacol 2003 Sep 18;140(2):239-46. Epub 2003 Aug 18.

Novartis Institutes for Biomedical Research, Central Technologies, Analytics and Imaging Sciences Unit, Lichtstr. 35, WSJ-386.2.09 CH-4002 Basel, Switzerland.

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September 2003

Effects of immunomodulators on airways hyperresponsiveness to adenosine induced in actively sensitised Brown Norway rats by exposure to allergen.

Authors:
Bruno Tigani Jason P Hannon Elisabeth Schaeublin Lazzaro Mazzoni John R Fozard

Naunyn Schmiedebergs Arch Pharmacol 2003 Jul 24;368(1):17-25. Epub 2003 Jun 24.

Novartis Institute for Biomedical Research, WSJ.386.508, 4002 Basel, Switzerland.

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July 2003

Noninvasive detection of endotoxin-induced mucus hypersecretion in rat lung by MRI.

Authors:
Nicolau Beckmann Bruno Tigani Rosemary Sugar Alan D Jackson Gareth Jones Lazzaro Mazzoni John R Fozard

Am J Physiol Lung Cell Mol Physiol 2002 Jul;283(1):L22-30

Central Technologies, Novartis Pharma, CH-4002 Basel, Switzerland.

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July 2002

Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.

Authors:
John R Fozard Karen M Ellis Maria F Villela Dantas Bruno Tigani Lazzaro Mazzoni

Eur J Pharmacol 2002 Mar;438(3):183-8

Research Department, Novartis Pharma AG, WSJ-386.510, CH-4002, Basel, Switzerland.

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March 2002

Pharmacological profile of a novel phosphodiesterase 4 inhibitor, 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid (NVP-ABE171), a 1,7-naphthyridine derivative, with anti-inflammatory activities.

Authors:
Alexandre Trifilieff Daniel Wyss Christoph Walker Lazzaro Mazzoni Rene Hersperger

J Pharmacol Exp Ther 2002 Apr;301(1):241-8

Novartis Horsham Respiratory Centre, Horsham, United Kingdom.

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April 2002

KCO912: a potent and selective opener of ATP-dependent potassium (K(ATP)) channels which suppresses airways hyperreactivity at doses devoid of cardiovascular effects.

Authors:
Karl-Heinz Buchheit Paul W Manley Ulrich Quast Ulrich Russ Lazzaro Mazzoni John R Fozard

Naunyn Schmiedebergs Arch Pharmacol 2002 Mar 23;365(3):220-30. Epub 2002 Jan 23.

Present address: EDQM, Council of Europe, B.P. 907, 67029 Strasbourg Cedex 1, France.

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March 2002