Publications by authors named "Layal Chaker"

60Publications

THYROID FUNCTION AND PHYSICAL ACTIVITY: A POPULATION-BASED COHORT STUDY.

Thyroid 2020 Nov 16. Epub 2020 Nov 16.

Erasmus MC, Thyroid Center Rotterdam, Department of Endocrinology, Room Ee500, Dr. Molewaterplein 50, Rotterdam, Netherlands, 3015 GE;

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http://dx.doi.org/10.1089/thy.2020.0517DOI Listing
November 2020

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

Authors:
Mathias Gorski Bettina Jung Yong Li Pamela R Matias-Garcia Matthias Wuttke Stefan Coassin Chris H L Thio Marcus E Kleber Thomas W Winkler Veronika Wanner Jin-Fang Chai Audrey Y Chu Massimiliano Cocca Mary F Feitosa Sahar Ghasemi Anselm Hoppmann Katrin Horn Man Li Teresa Nutile Markus Scholz Karsten B Sieber Alexander Teumer Adrienne Tin Judy Wang Bamidele O Tayo Tarunveer S Ahluwalia Peter Almgren Stephan J L Bakker Bernhard Banas Nisha Bansal Mary L Biggs Eric Boerwinkle Erwin P Bottinger Hermann Brenner Robert J Carroll John Chalmers Miao-Li Chee Miao-Ling Chee Ching-Yu Cheng Josef Coresh Martin H de Borst Frauke Degenhardt Kai-Uwe Eckardt Karlhans Endlich Andre Franke Sandra Freitag-Wolf Piyush Gampawar Ron T Gansevoort Mohsen Ghanbari Christian Gieger Pavel Hamet Kevin Ho Edith Hofer Bernd Holleczek Valencia Hui Xian Foo Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Navya Shilpa Josyula Mika Kähönen Chiea-Chuen Khor Wolfgang Koenig Holly Kramer Bernhard K Krämer Brigitte Kühnel Leslie A Lange Terho Lehtimäki Wolfgang Lieb Ruth J F Loos Mary Ann Lukas Leo-Pekka Lyytikäinen Christa Meisinger Thomas Meitinger Olle Melander Yuri Milaneschi Pashupati P Mishra Nina Mononen Josyf C Mychaleckyj Girish N Nadkarni Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Michelle L O'Donoghue Marju Orho-Melander Sarah A Pendergrass Brenda W J H Penninx Michael H Preuss Bruce M Psaty Laura M Raffield Olli T Raitakari Rainer Rettig Myriam Rheinberger Kenneth M Rice Alexander R Rosenkranz Peter Rossing Jerome I Rotter Charumathi Sabanayagam Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Sanaz Sedaghat Christian M Shaffer Konstantin Strauch Silke Szymczak Kent D Taylor Johanne Tremblay Layal Chaker Pim van der Harst Peter J van der Most Niek Verweij Uwe Völker Melanie Waldenberger Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Tien-Yin Wong Mark Woodward Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Yan Zhang Harold Snieder Christoph Wanner Carsten A Böger Anna Köttgen Florian Kronenberg Cristian Pattaro Iris M Heid

Kidney Int 2020 Oct 30. Epub 2020 Oct 30.

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2020.09.030DOI Listing
October 2020

Variation in Normal Range Thyroid Function Affects Serum Cholesterol Levels, Blood Pressure, and Type 2 Diabetes Risk: A Mendelian Randomization Study.

Thyroid 2020 Sep 9. Epub 2020 Sep 9.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1089/thy.2020.0393DOI Listing
September 2020

Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study.

J Clin Endocrinol Metab 2020 Aug;105(8)

Academic Center for Thyroid Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/clinem/dgaa239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316221PMC
August 2020

The Genetic Basis of Thyroid Function: Novel Findings and New Approaches.

J Clin Endocrinol Metab 2020 Jun;105(6)

Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/clinem/dgz225DOI Listing
June 2020

Thyroid Function and the Risk of Fibrosis of the Liver, Heart, and Lung in Humans: A Systematic Review and Meta-Analysis.

Thyroid 2020 06 13;30(6):806-820. Epub 2020 Feb 13.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1089/thy.2019.0572DOI Listing
June 2020

Development of Risk Prediction Equations for Incident Chronic Kidney Disease.

Authors:
Robert G Nelson Morgan E Grams Shoshana H Ballew Yingying Sang Fereidoun Azizi Steven J Chadban Layal Chaker Stephan C Dunning Caroline Fox Yoshihisa Hirakawa Kunitoshi Iseki Joachim Ix Tazeen H Jafar Anna Köttgen David M J Naimark Takayoshi Ohkubo Gordon J Prescott Casey M Rebholz Charumathi Sabanayagam Toshimi Sairenchi Ben Schöttker Yugo Shibagaki Marcello Tonelli Luxia Zhang Ron T Gansevoort Kunihiro Matsushita Mark Woodward Josef Coresh Varda Shalev John Chalmers Hisatomi Arima Vlado Perkovic Mark Woodward Josef Coresh Kunihiro Matsushita Morgan Grams Yingying Sang Kevan Polkinghorne Robert Atkins Steven Chadban Luxia Zhang Ming-Hui Zhao Fang Wang Jinwei Wang Marcello Tonelli Frank Sacks Gary Curhan Michael Shlipak Mark Sarnak Ronit Katz Jade Hiramoto Hiroyasu Iso Isao Muraki Kazumasa Yamagishi Mitsumasa Umesawa Hermann Brenner Ben Schöttker Kai-Uwe Saum Dietrich Rothenbacher Caroline Fox Shih-Jen Hwang Alex Chang Jamie Green Gurmukteshwar Singh H Lester Kirchner Corri Black Angharad Marks Gordon Prescott Laura Clark Nick Fluck Massimo Cirillo Stein Hallan Marius Øvrehus Knut Langlo Solfrid Romundstad Fujiko Irie Toshimi Sairenchi Adolfo Correa Casey Rebholz Bessie Young L Ebony Boulware Stanford Mwasongwe Tsuyoshi Watanabe Kunihiro Yamagata Kunitoshi Iseki Koichi Asahi Gabriel Chodick Varda Shalev Michael Shlipak Mark Sarnak Ronit Katz Carmen Peralta Erwin Bottinger Girish Nadkarni Stephen Ellis Rajiv Nadukuru Timothy Kenealy C Raina Elley John Collins Paul Drury Takayoshi Ohkubo Kei Asayama Masahiro Kikuya Hirohito Metoki Masaaki Nakayama Kunitoshi Iseki Chiho Iseki Robert Nelson Helen Looker William Knowler Ron Gansevoort Stephan Bakker Hiddo Heerspink Simerjot Jassal Jaclyn Bergstrom Joachim Ix Elizabeth Barrett-Connor Csaba Kovesdy Keiichi Sumida Kamyar Kalantar-Zadeh Sanaz Sedaghat Layal Chaker Arfan Ikram Ewout Hoorn Abbas Dehghan Juan Carrero Marie Evans Carl-Gustaf Elinder Tien Wong Charumathi Sabanayagam Ching-Yu Cheng Chi-Pang Wen Chwen-Keng Tsao Min-Kuang Tsai Chien-Hua Chen Farhad Hosseinpanah Farzad Hadaegh Fereidoun Azizi Mohammadhassan Mirbolouk Marit Solbu Bjørn Eriksen Trond Jenssen Anne Eggen Lars Lannfelt Anders Larsson Johan Ärnlöv Henk Bilo Gijs Landman Kornelis Hateren Nanne Kleefstra Stephan Dunning Nikita Stempniewicz John Cuddeback Elizabeth Ciemins Josef Coresh Morgan Grams Shoshana Ballew Kunihiro Matsushita Mark Woodward Ron Gansevoort Alex Chang Stein Hallan Anna Köttgen Csaba Kovesdy Andrew Levey Varda Shalev Luxia Zhang Shoshana Ballew Jingsha Chen Josef Coresh Morgan Grams Lucia Kwak Kunihiro Matsushita Yingying Sang Aditya Surapeneni Mark Woodward

JAMA 2019 11 8. Epub 2019 Nov 8.

Medical Division, Maccabi Healthcare Services, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1001/jama.2019.17379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865298PMC
November 2019

Thyroid Function and Cardiovascular Disease: The Mediating Role of Coagulation Factors.

J Clin Endocrinol Metab 2019 08;104(8):3203-3212

Department of Internal Medicine, Netherlands Academic Center for Thyroid Diseases, Erasmus Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2019-00072DOI Listing
August 2019

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-018-06356-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203810PMC
October 2018

Clinical aspects of thyroid function during ageing.

Lancet Diabetes Endocrinol 2018 09 17;6(9):733-742. Epub 2018 Jul 17.

Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(18)30028-7DOI Listing
September 2018

Hypothyroidism and hypertension: fact or myth? - Authors' reply.

Lancet 2018 01;391(10115):30

Academic Centre for Thyroid Disease, Erasmus University Medical Centre, Rotterdam 3015 CE, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)33321-4DOI Listing
January 2018

High Circulating Free Thyroxine Levels May Increase the Risk of Frailty: The Rotterdam Study.

J Clin Endocrinol Metab 2018 01;103(1):328-335

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2017-01854DOI Listing
January 2018

Thyroid Function and the Risk of Atherosclerotic Cardiovascular Morbidity and Mortality: The Rotterdam Study.

Circ Res 2017 Dec 31;121(12):1392-1400. Epub 2017 Oct 31.

From the Department of Internal Medicine (A.B., L.C., F.U.S.M.-R., R.P.P.), Academic Center for Thyroid Diseases (A.B., L.C., R.P.P.), Department of Epidemiology (A.B., L.C., M.A.I., O.H.F., R.P.P., M.K.), Section of Geriatric Medicine, Department of Internal Medicine (F.U.S.M.-R.), and Department of Radiology (A.v.d.L.), Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (L.C.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311603DOI Listing
December 2017

Age-dependent association of thyroid function with brain morphology and microstructural organization: evidence from brain imaging.

Neurobiol Aging 2018 01 22;61:44-51. Epub 2017 Sep 22.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580173030
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http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.014DOI Listing
January 2018

Improving the clinical impact of randomised trials in thyroidology.

Lancet Diabetes Endocrinol 2018 07 10;6(7):523-525. Epub 2017 Oct 10.

Academic Center for Thyroid Diseases, Erasmus University Medical Center, 3000 CA, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/S2213-8587(17)30316-9DOI Listing
July 2018

Childhood Thyroid Function Reference Ranges and Determinants: A Literature Overview and a Prospective Cohort Study.

Thyroid 2017 11 24;27(11):1360-1369. Epub 2017 Oct 24.

1 The Generation R Study Group, Erasmus Medical Center-Sophia Children's Hospital , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2017.0262DOI Listing
November 2017

Thyroid Function and Premature Delivery in TPO Antibody-Negative Women: The Added Value of hCG.

J Clin Endocrinol Metab 2017 09;102(9):3360-3367

Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00846DOI Listing
September 2017

Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma.

J Clin Endocrinol Metab 2017 08;102(8):2922-2929

Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2016-4025DOI Listing
August 2017

Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease.

J Clin Endocrinol Metab 2017 08;102(8):2853-2861

Department of Epidemiology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00410DOI Listing
August 2017

A Step Forward in Understanding the Relevance of Genetic Variation in Type 2 Deiodinase.

J Clin Endocrinol Metab 2017 05;102(5):1775-1778

Department of Internal Medicine, Academic Center for Thyroid Disease, Erasmus Medical Center, Rotterdam 3015 GE, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00585DOI Listing
May 2017

Response to the Letter by Choy.

J Clin Endocrinol Metab 2017 04;102(4):1409-1410

Rotterdam Thyroid Center.

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http://dx.doi.org/10.1210/jc.2016-3502DOI Listing
April 2017

Hypothyroidism.

Lancet 2017 Sep 20;390(10101):1550-1562. Epub 2017 Mar 20.

Academic Centre for Thyroid Disease, Erasmus University Medical Centre, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30703-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619426PMC
September 2017

Response by Chaker et al to Letter Regarding Article, "Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study".

Circulation 2017 02;135(8):e90-e91

From Rotterdam Thyroid Center (L.C., R.P.P.), Department of Internal Medicine (L.C., B.H.S., R.P.P.), and Department of Epidemiology (L.C., M.v.d.B., B.H.S., R.P.P.), Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026724DOI Listing
February 2017

Gait patterns associated with thyroid function: The Rotterdam Study.

Sci Rep 2016 12 14;6:38912. Epub 2016 Dec 14.

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/srep38912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155238PMC
December 2016

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.

J Clin Endocrinol Metab 2016 11 7;101(11):4270-4282. Epub 2016 Sep 7.

Departments of Internal Medicine (R.P.P., L.C., M.M.) and Epidemiology (R.P.P., O.H.F., A.D., A.H., A.I., L.C., M.L.P.P.), Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands; Rotterdam Thyroid Center (R.P.P., L.C., M.M.) and Department of Radiology and Neurology (M.A.I.), Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands; Department of General Internal Medicine (N.R., C.B., M.R.B.), Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; Service of Endocrinology, Diabetes, and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; Departments of Clinical Chemistry and Laboratory Medicine (W.P.J.d.E.), Public Health and Primary Care (J.G.), and Cardiology (W.J.), Leiden University Medical Center, 2300 RC Leiden, The Netherlands; Departments of Medicine and Epidemiology and Biostatistics (D.C.B.), University of California, San Francisco, San Francisco, California 94143; Division of Endocrinology, Diabetes, and Metabolism (A.R.C.), Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Epidemiology (A.H.), Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115; Department of Endocrinology (S.R.), Gateshead Health Foundation National Health Service Trust, Gateshead, SE18 4QH, United Kingdom; Department of Endocrinology and Diabetes (J.P.W.), Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia; Schools of Medicine and Pharmacology (J.P.W.) and Population Health (A.B.), University of Western Australia, Crawley, Western Australia 6009, Australia; National Council Research Institute of Clinical Physiology (G.I.), 56124 Pisa, Italy; Robertson Centre for Biostatistics (I.F.) and Institute of Cardiovascular and Medical Sciences (D.J.S.), Faculty of Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom; Department of Epidemiology (A.B.N.), University of Pittsburgh, Pittsburgh, Pennsylvania 15260; Department of Internal Medicine (S.J.L.B., R.P.D.), University Medical Center, University of Groningen, 9700 AB Groningen, The Netherlands; Department of Medicine (C.W., C.D.), Division of Nephrology, University Hospital of Würzburg, and Comprehensive Heart Failure Centre (C.W., C.D.), 97070 Würzburg, Germany; Department of Clinical Studies (M.I.), Radiation Effects Research Foundation, Nagasaki 850-8555, Japan; Department of Clinical and Experimental Medicine (G.C.), University of Parma, 143100 Parma, Italy; National Institute on Aging (L.F.), Baltimore, Maryland 21225; Institute for Community Medicine (H.V.), Clinical-Epidemiological Research/Study of Health in Pomerania, University Medicine, German Centre of Cardiovascular Research, Partner Site, Department of Internal Medicine (M.D.), and University Medicine (M.D.), German Centre of Cardiovascular Research, Partner Site, 17487 Greifswald, Germany; Departments of Neurology and Epidemiology (W.T.L.), and Cardiovascular Health Research Unit (W.T.L.), Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington 98108; Group Health Research Institute (B.M.P.), Group Health Cooperative, Seattle, Washington 98101; Division of Endocrinology (R.M.B.M., J.A.S.), Department of Medicine, Federal University of Sao Paulo, 05508-900 São Paulo, Brazil; Division of Endocrinology (J.A.S.), Faculdade de Medicina de Marília, Marília, Brazil; Department of Public Health and Primary Care (R.N.L., K.-T.K.), University of Cambridge, Cambridge CB2 1TN, United Kingdom; Interuniversity Cardiology Institute of The Netherlands (W.J.), 3508 GA Utrecht, The Netherlands; School of Clinical and Experimental Medicine (J.A.F.), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; and Department of Public Health and Center for Healthy Ageing (R.G.W.), Faculty of Health and Medical Sciences, University of Copenhagen, DK-2400 Copenhagen, Denmark.

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http://dx.doi.org/10.1210/jc.2016-2255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095234PMC
November 2016

Thyroid function and the risk of dementia: The Rotterdam Study.

Neurology 2016 Oct 16;87(16):1688-1695. Epub 2016 Sep 16.

From the Rotterdam Thyroid Center (L.C., T.I.M.K., R.P.P.) and Departments of Internal Medicine (L.C., T.I.M.K., R.P.P.), Epidemiology (L.C., F.J.W., D.B., T.I.M.K., A.H., O.H.F., A.D., M.W.V., R.P.P., M.A.I.), Neurology (F.J.W., P.J.K., M.A.I.), and Radiology (D.B., A.v.d.L., M.W.V., M.A.I.), Erasmus University Medical Center, Rotterdam, the Netherlands; and Department of Epidemiology (A.H.), Harvard T.H. Chan School of Public Health, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000003227DOI Listing
October 2016

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

J Clin Endocrinol Metab 2016 12 30;101(12):4945-4954. Epub 2016 Sep 30.

Department of General Internal Medicine (C.R., D.S., C.E.A., C.B., D.A., N.R.), Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; Institute of Primary Health Care (BIHAM), Faculty of Medicine (B.R.d.C., N.R.), University of Bern, 3012 Bern, Switzerland; Service of Endocrinology, Diabetes and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; University of Cambridge Metabolic Research Laboratories (T.-H.C.), Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom; Department of Epidemiology (L.C., R.P.P.), Rotterdam Thyroid Center, 3015 GE Rotterdam, The Netherlands; School of Psychiatry and Clinical Neurosciences (O.P.A.), University of Western Australia, Perth 6009, Australia; School of Sport, Exercise and Health Sciences (E.H.), Loughborough University, Loughborough LE11 3TU, United Kingdom; Department of Cardiology (S.T.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Kuakini Medical Center and the Department of Geriatric Medicine (K.M.), John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96817; Department of Gerontology and Geriatrics (S.P.M.), Leiden University Medical Center, Leiden and Institute for Evidence-based Medicine in Old Age (IEMO), 2333 ZA Leiden, The Netherlands; Department of Public Health and Primary Care (J.G.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; and Department of Medicine (D.C.B.), University of California-San Francisco, San Francisco California 94143.

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http://dx.doi.org/10.1210/jc.2016-2129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287525PMC
December 2016

Thyroid function and risk of type 2 diabetes: a population-based prospective cohort study.

BMC Med 2016 Sep 30;14(1):150. Epub 2016 Sep 30.

Department of Epidemiology, Erasmus University Medical Center, Room NA-2828, 3000CA, Rotterdam, The Netherlands.

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http://bmcmedicine.biomedcentral.com/articles/10.1186/s12916
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043536PMC
http://dx.doi.org/10.1186/s12916-016-0693-4DOI Listing
September 2016

The Risk of Preeclampsia According to High Thyroid Function in Pregnancy Differs by hCG Concentration.

J Clin Endocrinol Metab 2016 12 20;101(12):5037-5043. Epub 2016 Sep 20.

The Generation R Study Group (T.I.M.K., E.A.P.S., M.M., V.W.V.J.) and Departments of Internal Medicine (T.I.M.K., L.C., M.M., T.J.V., R.B.P.), Obstetrics and Gynecology (E.A.P.S.), Pediatrics (V.W.V.J.), Epidemiology (V.W.V.J.), and Clinical Chemistry (Y.B.d.R.), Erasmus Medical Center and/or Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands; and Rotterdam Thyroid Center (T.I.M.K., L.C., M.M., T.J.V., R.B.P.), Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2016-2397DOI Listing
December 2016

Thyroid Function and Cancer Risk: The Rotterdam Study.

J Clin Endocrinol Metab 2016 12 20;101(12):5030-5036. Epub 2016 Sep 20.

Rotterdam Thyroid Center (S.R.K., L.C., R.P.P.), Department of Epidemiology (S.R.K., L.C., R.R., A.H., A.D., O.H.F., B.H.C.S., R.P.P.), Department of Internal Medicine (L.C., R.P.P.), and Department of Pulmonology (J.G.J.V.A.), Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands; and Department of Epidemiology (A.H.), Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2016-2104DOI Listing
December 2016

Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study.

Circulation 2016 Sep;134(10):713-22

From Rotterdam Thyroid Center (L.C., R.P.P.), Department of Internal Medicine (L.C., B.H.C.S., R.P.P.), and Department of Epidemiology (L.C., M.E.v.d.B., M.N.N., O.H.F., A.D., A.H., M.E., B.H.C.S., R.P.P.), Erasmus University Medical Center; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (A.H.); Departments of Medical Informatics (P.R.R.) and Cardiology (J.W.D.), Erasmus University Medical Center, Rotterdam, The Netherlands; and Inspectorate of Health Care, Utrecht, The Netherlands (B.H.C.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020789DOI Listing
September 2016

Thyroid Function Characteristics and Determinants: The Rotterdam Study.

Thyroid 2016 09;26(9):1195-204

1 Rotterdam Thyroid Center, Erasmus University Medical Center , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2016.0133DOI Listing
September 2016

Thyroid Function and the Risk of Nonalcoholic Fatty Liver Disease: The Rotterdam Study.

J Clin Endocrinol Metab 2016 08 7;101(8):3204-11. Epub 2016 Jun 7.

Department of Internal Medicine (A.B., L.C., R.P.P.), Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands; Rotterdam Thyroid Center (A.B., L.C., R.P.P.), Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands; Department of Epidemiology (A.B., L.C., E.P.C.P., A.H., A.D., O.H.F., S.D.M., R.P.P.), Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands; Department of Gastroenterology and Hepatology (E.P.C.P., H.L.A.J., S.D.M.), Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands; and Toronto Centre for Liver Disease (H.L.A.J.), Toronto Western and General Hospital, University Health Network, Toronto, Ontario, M5G 2C4 Canada.

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August 2016

Thyroid function: Thyroid dysfunction and breast cancer risk - an unfinished story.

Nat Rev Endocrinol 2016 06 29;12(6):313-4. Epub 2016 Mar 29.

Department of Internal Medicine, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, Netherlands.

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http://dx.doi.org/10.1038/nrendo.2016.48DOI Listing
June 2016

Maternal and Birth Characteristics Are Determinants of Offspring Thyroid Function.

J Clin Endocrinol Metab 2016 Jan 19;101(1):206-13. Epub 2015 Nov 19.

The Generation R Study Group (T.I.M.K., V.W.V.J., M.M.) and Departments of Internal Medicine (T.I.M.K., L.C., T.J.V., M.M., R.P.P.), Pediatrics (V.W.V.J.), and Epidemiology (V.W.V.J.), Erasmus Medical Center-Sophia Children's Hospital, 3000 CA, Rotterdam, The Netherlands; and Rotterdam Thyroid Center (T.I.M.K., L.C., T.J.V., M.M., R.P.P.), Erasmus Medical Center, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-3559DOI Listing
January 2016

Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study.

Lancet Diabetes Endocrinol 2016 Jan 20;4(1):35-43. Epub 2015 Oct 20.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/S2213-8587(15)00327-7DOI Listing
January 2016

Normal Thyroid Function and the Risk of Atrial Fibrillation: the Rotterdam Study.

J Clin Endocrinol Metab 2015 Oct 11;100(10):3718-24. Epub 2015 Aug 11.

Rotterdam Thyroid Center (L.C., M.M., W.E.V., R.P.P.), Department of Internal Medicine (L.C., M.M., W.E.V., R.P.P.), and Department of Epidemiology (L.C., J.H., A.D., A.H., O.H.F.), Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands; and Department of General Internal Medicine (C.B., N.R.), Inselspital, University Hospital of Bern, 3010 Bern, Switzerland.

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http://dx.doi.org/10.1210/jc.2015-2480DOI Listing
October 2015

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis.

J Clin Endocrinol Metab 2015 Jun 9;100(6):2181-91. Epub 2015 Apr 9.

Department of Internal Medicine (L.C., M.M., R.P.P.), and Rotterdam Thyroid Center, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands; Department of Epidemiology (L.C., M.A.I., A.D., A.H., M.L.P.P., O.H.F.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Department of General Internal Medicine (C.B., M.R.B., N.R.), Inselspital, Bern University Hospital, 3010 Bern, Switzerland; Departments of Epidemiology, Public Health, and Primary Care (W.P.J.d.E., J.G.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Department of Radiology (M.A.I.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Department of Neurology (M.A.I., M.L.P.P.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Service of Endocrinology, Diabetes, and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; Department of Internal Medicine (S.J.L.B., R.P.D.), University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands; Department of Medicine (C.D., C.W.), Division of Nephrology, University Hospital of Würzburg, Germany Comprehensive Heart Failure Centre, D-97080 Würzburg, Germany; Department of Public Health and Primary Care (R.N.L., K.-T.K.), University of Cambridge, Cambridge CB2 1TN, United Kingdom; National Council Research Institute of Clinical Physiology (G.I.), Pisa 56124, Italy; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine (D.J.S.), and Robertson Centre for Biostatistics (I.F.), University of Glasgow, Glasgow G12 8QQ, United Kingdom; School of Population Health (A.B.), University of Western Australia, Crawley, Perth 6009, Western Australia, Australia; National Institute on Aging (L.F.), Baltimore, Maryland 20892; Department of Epidemiology (A.B.N.), University of Pittsburgh, Pittsburgh, Pennsylvania 15260; Division of Endocrinology (J.A.S.), Faculdade de Medicina de Marília, Marília, Sao Paulo 17519, Brazil; Di

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http://dx.doi.org/10.1210/jc.2015-1438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454799PMC
June 2015

The global impact of non-communicable diseases on macro-economic productivity: a systematic review.

Eur J Epidemiol 2015 May 3;30(5):357-95. Epub 2015 Apr 3.

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Office NA29-16, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s10654-015-0026-5
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457808PMC
May 2015

A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations.

J Clin Endocrinol Metab 2015 May 26;100(5):E799-807. Epub 2015 Feb 26.

Renal Division (U.T.S., Y.L., A.K.), Department of Medicine IV, Medical Center, University of Freiburg, 79106 Freiburg, Germany; Department of Internal Medicine and Rotterdam Thyroid Center (M.M., L.C., A.G.U., R.P.P.) and Department of Epidemiology (L.C., A.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; Institute for Community Medicine (A.T., H.V.), Interfaculty Institute for Genetics and Functional Genomics (G.H.), and Institute of Clinical Chemistry and Laboratory Medicine (M.N.), University Medicine Greifswald, 17475 Greifswald, Germany; and Department of Epidemiology (N.D., E.S., A.K.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205.

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http://dx.doi.org/10.1210/jc.2014-4352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422885PMC
May 2015

The global impact of non-communicable diseases on healthcare spending and national income: a systematic review.

Eur J Epidemiol 2015 Apr 18;30(4):251-77. Epub 2015 Jan 18.

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Office NA29-16, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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April 2015

The global impact of non-communicable diseases on households and impoverishment: a systematic review.

Eur J Epidemiol 2015 Mar 21;30(3):163-88. Epub 2014 Dec 21.

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Office NA 29-16, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s10654-014-9983-3
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March 2015

Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis.

Eur J Epidemiol 2014 Nov 2;29(11):791-800. Epub 2014 Sep 2.

Department of Internal Medicine, Thyroid Center, Erasmus University Medical Center, Room Ee502, PO Box 2040, 3000 CA, Rotterdam, The Netherlands,

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http://link.springer.com/10.1007/s10654-014-9946-8
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November 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Haemophagocytic syndrome and Hodgkin's disease variant of Richter's syndrome after fludarabine for CLL.

Eur J Haematol 2010 Jul 16;85(1):91-2. Epub 2010 Mar 16.

Department of Internal Medicine, Reinier de Graaf Gasthuis, Department of Pathology, Delft, the Netherlands.

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http://dx.doi.org/10.1111/j.1600-0609.2010.01444.xDOI Listing
July 2010