Lay Kek Teh

Lay Kek Teh

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Lay Kek Teh

Lay Kek Teh

Publications by authors named "Lay Kek Teh"

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Association of with levels and toxicity of methotrexate in Malaysian Childhood Acute Lymphoblastic Leukemia (ALL).

Pediatr Hematol Oncol 2020 Apr 23;37(3):185-197. Epub 2019 Dec 23.

Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Selangor, Malaysia.

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http://dx.doi.org/10.1080/08880018.2019.1705949DOI Listing
April 2020

Antinociceptive Activity of Petroleum Ether Fraction of Leaves Methanolic Extract: Roles of Nonopioid Pain Modulatory Systems and Potassium Channels.

Biomed Res Int 2019 5;2019:6593125. Epub 2019 Aug 5.

Integrative Pharmacogenomics Institute (iPROMISE), Level 7, FF3, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia.

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http://dx.doi.org/10.1155/2019/6593125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699298PMC
January 2020

Aqueous Partition of Methanolic Extract of Leaves Protects against Liver Damage Induced by Paracetamol.

Nutrients 2019 Dec 4;11(12). Epub 2019 Dec 4.

Integrative Pharmacogenomics Institute (I-PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam 42300, Selangor, Malaysia.

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http://dx.doi.org/10.3390/nu11122945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950669PMC
December 2019

A study on the genetic polymorphisms of CYP3A5 among the Orang Asli in Malaysia using a next generation sequencing platform.

Ann Hum Biol 2018 Mar 25;45(2):166-169. Epub 2018 Feb 25.

a Integrative Pharmacogenomics Institute (iPROMISE) , Universiti Teknologi MARA Selangor (UiTM) , ALAM , Malaysia.

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http://dx.doi.org/10.1080/03014460.2018.1440004DOI Listing
March 2018

Metabolomic-guided discovery of Alzheimer's disease biomarkers from body fluid.

J Neurosci Res 2017 10 16;95(10):2005-2024. Epub 2017 Mar 16.

Faculty of Pharmacy, University Teknologi MARA (UiTM), 42300 Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia.

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http://dx.doi.org/10.1002/jnr.24048DOI Listing
October 2017

Inference of the Genetic Polymorphisms of CYP2D6 in Six Subtribes of the Malaysian Orang Asli from Whole-Genome Sequencing Data.

Genet Test Mol Biomarkers 2017 Jul 19;21(7):409-415. Epub 2017 May 19.

1 Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM) , Puncak Alam, Malaysia .

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http://dx.doi.org/10.1089/gtmb.2016.0235DOI Listing
July 2017

Semipurified Ethyl Acetate Partition of Methanolic Extract of Leaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds.

Oxid Med Cell Longev 2017 11;2017:6542631. Epub 2017 Jan 11.

Department of Biomedical Science, Faculty of Medicine and Health Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA, Level 7, FF3 Building, 42300 Puncak Alam, Selangor, Malaysia.

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http://dx.doi.org/10.1155/2017/6542631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267083PMC
March 2017

Coupling Genotyping and Computational Modeling in Prediction of Anti-epileptic Drugs that cause Stevens Johnson Syndrome and Toxic Epidermal Necrolysis for Carrier of HLA-B*15:02.

J Pharm Pharm Sci 2016 ;19(1):147-60

Integrative Pharmacogenomics Institute, Universiti Teknologi MARA Selangor, Puncak Alam, Malaysia. Faculty of Pharmacy, Universiti Teknologi MARA Selangor, Puncak Alam, Malaysia.

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http://dx.doi.org/10.18433/J38G7XDOI Listing
February 2017

Gastroprotective activity of chloroform extract of Muntingia calabura and Melastoma malabathricum leaves.

Pharm Biol 2016 9;54(5):812-26. Epub 2015 Oct 9.

b Integrative Pharmacogenomics Institute (iPROMISE), Level 7, FF3, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Puncak Alam Campus , Selangor , Malaysia .

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http://dx.doi.org/10.3109/13880209.2015.1085580DOI Listing
December 2016

Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies.

Bioorg Chem 2016 08 13;67:9-17. Epub 2016 May 13.

Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia; Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia.

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http://dx.doi.org/10.1016/j.bioorg.2016.05.002DOI Listing
August 2016

Transgenerational effects of paternal heroin addiction on anxiety and aggression behavior in male offspring.

Behav Brain Funct 2016 Aug 31;12(1):23. Epub 2016 Aug 31.

Integrative Pharmacogenomics Institute (iPROMISE), Level 7, FF3, Universiti Teknologi MARA Selangor, Puncak Alam Campus, 42300, Bandar Puncak Alam, Selangor, Malaysia.

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http://dx.doi.org/10.1186/s12993-016-0107-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006377PMC
August 2016

Genome sequencing and annotation of multidrug resistant Mycobacterium tuberculosis (MDR-TB) PR10 strain.

Genom Data 2016 Mar 9;7:245-6. Epub 2016 Jan 9.

Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia; Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Selangor, Malaysia.

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http://dx.doi.org/10.1016/j.gdata.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778625PMC
March 2016

Metabolomics and partial least square discriminant analysis to predict history of myocardial infarction of self-claimed healthy subjects: validity and feasibility for clinical practice.

J Clin Bioinforma 2015 13;5. Epub 2015 Mar 13.

Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Puncak Alam Malaysia, Selangor 42300 Malaysia ; Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor 42300 Malaysia.

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http://dx.doi.org/10.1186/s13336-015-0018-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371619PMC
March 2015

Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients.

Can J Physiol Pharmacol 2014 Jan 19;92(1):50-7. Epub 2013 Dec 19.

a Integrative Pharmacogenomics Institute, Universiti Teknologi MARA (UiTM), 42300 Puncak Alam, Selangor DE, Malaysia.

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http://dx.doi.org/10.1139/cjpp-2013-0128DOI Listing
January 2014

Activity-Guided Isolation of Bioactive Constituents with Antinociceptive Activity from Muntingia calabura L. Leaves Using the Formalin Test.

Evid Based Complement Alternat Med 2013 21;2013:715074. Epub 2013 Nov 21.

Integrative Pharmacogenomics Institute, Universiti Teknologi MARA, 42300 Puncak Alam, Selangor, Malaysia ; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.

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http://dx.doi.org/10.1155/2013/715074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856150PMC
December 2013

Potential of dihydropyrimidine dehydrogenase genotypes in personalizing 5-fluorouracil therapy among colorectal cancer patients.

Ther Drug Monit 2013 Oct;35(5):624-30

*Pharmacogenomics Centre, Faculty of Pharmacy, Universiti Teknologi MARA; †Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia; ‡Department of Surgery, Kulliyah of Medicine, International Islamic University Malaysia, Kuantan, Malaysia; and §Department of Surgery, Faculty of Medicine, Universiti Teknologi MARA, Selangor, Malaysia.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FTD.0b013e318290acd2DOI Listing
October 2013

Pharmacogenomics of CYP2D6: molecular genetics, interethnic differences and clinical importance.

Drug Metab Pharmacokinet 2012 20;27(1):55-67. Epub 2011 Dec 20.

Pharmacogenomics Centre PROMISE, Faculty of Pharmacy, Universiti Teknologi MARA, Selangor DE, Malaysia.

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http://dx.doi.org/10.2133/dmpk.dmpk-11-rv-121DOI Listing
July 2012

Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes.

Eur J Clin Pharmacol 2012 Jul 1;68(7):1033-42. Epub 2012 Feb 1.

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet-Karolinska University Hospital, Huddinge 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00228-012-1210-0DOI Listing
July 2012

Influence of DRD2 polymorphisms on the clinical outcomes of patients with schizophrenia.

Psychiatr Genet 2011 Aug;21(4):183-9

Pharmacogenetics Research Group, Institute for Research in Molecular Medicine Hospital USM, Kelantan, Malaysia.

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http://dx.doi.org/10.1097/YPG.0b013e3283437250DOI Listing
August 2011

Influence of CYP2D6 polymorphisms on symptomatology and side-effects of patients with schizophrenia in Malaysia.

Malays J Med Sci 2009 Jul;16(3):12-20

Pharmacogenetics Research Group, Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia Health Campus & Department of Pharmacy, Hospital Universiti Sains Malaysia, Universiti Sains Malaysia Health Campus, Jln Raja Perempuan Zainab II, 16150 Kubang Kerian, Kelantan, Malaysia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329140PMC
July 2009

Functional role of Ile264 in CYP2C8: mutations affect haem incorporation and catalytic activity.

Drug Metab Pharmacokinet 2008 ;23(3):165-74

School of Pharmacy and Health Sciences, International Medical University, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.2133/dmpk.23.165DOI Listing
August 2008