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Publications Authored by Lawryn H Kasper | PubFacts
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23Publications

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ChIPseqSpikeInFree: A ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in.

Bioinformatics 2019 Sep 30. Epub 2019 Sep 30.

Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz720DOI Listing
September 2019

Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.

PLoS One 2016 5;11(1):e0146366. Epub 2016 Jan 5.

Department of Biochemistry, St Jude Children's Research Hospital, Memphis, TN 38105, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146366PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701386PMC
August 2016

T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs.

PLoS One 2014 23;9(7):e102076. Epub 2014 Jul 23.

Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102076PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108324PMC
April 2015

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Nucleic Acids Res 2014 Oct 23;42(18):11363-82. Epub 2014 Sep 23.

Department of Biochemistry, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1093/nar/gku827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191404PMC
October 2014

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.

Nat Genet 2012 Oct 2;44(10):1104-10. Epub 2012 Sep 2.

Department of Translational Genomics, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1038/ng.2396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915822PMC
October 2012

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

EMBO J 2011 Jan 3;30(2):249-62. Epub 2010 Dec 3.

Nuclear Receptor Biology Section, CEB, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2010.318
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http://dx.doi.org/10.1038/emboj.2010.318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025463PMC
January 2011

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.

Cell Cycle 2011 Jan 15;10(2):212-21. Epub 2011 Jan 15.

Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048793PMC
http://dx.doi.org/10.4161/cc.10.2.14542DOI Listing
January 2011

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.

EMBO J 2010 Nov 21;29(21):3660-72. Epub 2010 Sep 21.

Department of Biochemistry, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1038/emboj.2010.235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982758PMC
November 2010

Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases.

Epigenetics 2010 Jan 27;5(1):9-15. Epub 2010 Jan 27.

Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829352PMC
http://dx.doi.org/10.4161/epi.5.1.10449DOI Listing
January 2010

Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development.

Mol Cell Biol 2009 Jul 11;29(14):3894-904. Epub 2009 May 11.

Department of Biochemistry, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1128/MCB.01598-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704754PMC
July 2009

Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms.

EMBO J 2007 Jun 24;26(12):2890-903. Epub 2007 May 24.

Department of Biochemistry, St Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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http://emboj.embopress.org/cgi/doi/10.1038/sj.emboj.7601734
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http://dx.doi.org/10.1038/sj.emboj.7601734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894772PMC
June 2007

Mammalian gene expression program resiliency: the roles of multiple coactivator mechanisms in hypoxia-responsive transcription.

Cell Cycle 2006 Jan 16;5(2):142-6. Epub 2006 Jan 16.

Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.4161/cc.5.2.2353DOI Listing
January 2006

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

EMBO J 2005 Nov 20;24(22):3846-58. Epub 2005 Oct 20.

Department of Biochemistry, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283945PMC
November 2005

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

Nature 2002 Oct;419(6908):738-43

Department of Biochemistry, St Jude Children's Research Hospital, 332 North Lauderdale, Memphis, Tennessee 38105, USA.

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http://www.nature.com/articles/nature01062
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http://dx.doi.org/10.1038/nature01062DOI Listing
October 2002