Lawrence W Castellani

Lawrence W Castellani

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Lawrence W Castellani

Lawrence W Castellani

Publications by authors named "Lawrence W Castellani"

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Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.

J Cell Sci 2015 Jun 8;128(12):2236-48. Epub 2015 May 8.

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90024, USA Molecular Biology Institute, University of California, Los Angeles, CA 90024, USA Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90024, USA

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http://dx.doi.org/10.1242/jcs.163774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487014PMC
June 2015

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis.

FASEB J 2015 Apr 4;29(4):1185-97. Epub 2014 Dec 4.

*Division of Cardiology, Department of Medicine, Department of Microbiology, Immunology, and Molecular Genetics, Department of Human Genetics, Department of Molecular and Medical Pharmacology, and Department of Medicine and Molecular Biology Institute, University of California at Los Angeles, Los Angeles, California, USA; IGBMC, Illkirch and Hôpitaux Universitaires de Strasbourg, and **Laboratoire de Toxicologie, Universitaires de Strasbourg, Strasbourg, France; Department of Biochemistry and Molecular Biology, and Center for Cardiovascular Research, St. Louis University School of Medicine, St. Louis, Missouri, USA; University of Alberta, Edmonton, Alberta, Canada; and Laboratory for Integrative and Systems Physiology, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://www.fasebj.org/content/early/2014/12/03/fj.14-260570.
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http://www.fasebj.org/cgi/doi/10.1096/fj.14-260570
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http://dx.doi.org/10.1096/fj.14-260570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396607PMC
April 2015

Genetic architecture of insulin resistance in the mouse.

Cell Metab 2015 Feb;21(2):334-347

Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349439PMC
February 2015

Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice.

PLoS One 2014 28;9(1):e85341. Epub 2014 Jan 28.

Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America ; Cancer Science Institute of Singapore and National Cancer Institute, National University of Singapore, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085341PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904867PMC
December 2014

A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models.

Biochim Biophys Acta 2012 Mar 23;1821(3):435-47. Epub 2011 Jul 23.

Department of Human Genetics, David Geffen School of Medicine at UCLA, Gonda (Goldschmied) Neuroscience and Genetics Research Center, 695 Charles E. Young Drive South, Box 708822, Los Angeles, CA 90095-7088, USA.

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http://dx.doi.org/10.1016/j.bbalip.2011.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265689PMC
March 2012

Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice.

Hum Mol Genet 2010 Feb 8;19(4):597-608. Epub 2009 Dec 8.

Department of Human Genetics, David Geffen School of Medicine at University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/hmg/ddp526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807368PMC
February 2010

Chylomicronemia elicits atherosclerosis in mice--brief report.

Arterioscler Thromb Vasc Biol 2010 Jan 8;30(1):20-3. Epub 2009 Oct 8.

Departments of Medicine, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.196329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796285PMC
January 2010

Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.

Diabetes 2009 Aug 9;58(8):1739-48. Epub 2009 Jun 9.

Department of Molecular Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db09-0349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712781PMC
August 2009

The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia.

Endocrinology 2008 May 31;149(5):2208-18. Epub 2008 Jan 31.

Larry L. Hillblom Islet Research Center, University of California Los Angeles, Los Angeles, California 90095-7345, USA.

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http://dx.doi.org/10.1210/en.2007-1059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734491PMC
May 2008

Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance.

J Biol Chem 2008 Apr 26;283(17):11633-44. Epub 2007 Dec 26.

Departments of Medicine/Cardiology University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1074/jbc.M708995200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431075PMC
April 2008

ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.

J Lipid Res 2007 Apr 26;48(4):794-805. Epub 2007 Jan 26.

Division of Rheumatology, Department of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1194/jlr.M600512-JLR200DOI Listing
April 2007

Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.

Biochim Biophys Acta 2006 Aug 18;1764(8):1363-71. Epub 2006 Jun 18.

The Molecular Biology Institute and The Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.bbapap.2006.06.001DOI Listing
August 2006

Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males.

J Lipid Res 2006 Jul 25;47(7):1366-77. Epub 2006 Apr 25.

Department of Medicine, University of California-Los Angeles, 90095, USA.

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http://dx.doi.org/10.1194/jlr.M600005-JLR200DOI Listing
July 2006

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits.

Nat Genet 2005 Nov 2;37(11):1224-33. Epub 2005 Oct 2.

Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095-1679, USA.

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http://dx.doi.org/10.1038/ng1619DOI Listing
November 2005

The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity.

J Clin Endocrinol Metab 2005 Aug 31;90(8):4816-23. Epub 2005 May 31.

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard., Becker B-128, Los Angeles, California 90048, USA.

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http://dx.doi.org/10.1210/jc.2005-0389DOI Listing
August 2005

Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition.

J Lipid Res 2005 Jan 1;46(1):123-34. Epub 2004 Nov 1.

Department of Human Genetics, Medicine, Molecular Biology Institute, University of California, Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M400341-JLR200
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http://dx.doi.org/10.1194/jlr.M400341-JLR200DOI Listing
January 2005

Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II.

J Lipid Res 2004 Dec 1;45(12):2377-87. Epub 2004 Oct 1.

Department of Medicine, 47-123 CHS, University of California, Los Angeles, CA 90095, USA.

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http://www.jlr.org/content/45/12/2377.full.pdf
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http://www.jlr.org/cgi/doi/10.1194/jlr.M400345-JLR200
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http://dx.doi.org/10.1194/jlr.M400345-JLR200DOI Listing
December 2004

Coronary vasomotor abnormalities in insulin-resistant individuals.

Ann Intern Med 2004 May;140(9):700-8

Division of Endocrinology, Diabetes and Hypertension, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.7326/0003-4819-140-9-200405040-00009DOI Listing
May 2004

ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36.

J Lipid Res 2004 Apr 16;45(4):706-15. Epub 2004 Jan 16.

Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1194/jlr.M300417-JLR200DOI Listing
April 2004

Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.

Biochem Biophys Res Commun 2004 Apr;317(1):223-9

Department of Radiology, University of Virginia, Charlottesville 22908, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.037DOI Listing
April 2004

Mice heterozygous for Atp10c, a putative amphipath, represent a novel model of obesity and type 2 diabetes.

J Nutr 2004 Apr;134(4):799-805

Department of Nutrition, University of Tennessee, Knoxville, TN 37996, USA.

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http://dx.doi.org/10.1093/jn/134.4.799DOI Listing
April 2004

Dissection of multigenic obesity traits in congenic mouse strains.

Mamm Genome 2004 Jan;15(1):14-22

Department of Human Genetics, Gonda/Goldschmeid Center for Neuroscience and Human Genetics Research, 695 Charles E Young Dr South, Room 6524, Los Angeles, CA 90095-7088, USA.

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http://dx.doi.org/10.1007/s00335-003-2294-8DOI Listing
January 2004

Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR.

Genes Dev 2004 Jan 16;18(2):157-69. Epub 2004 Jan 16.

Department of Biological Chemistry, University of California at Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1101/gad.1138104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC324422PMC
January 2004

Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia.

Circ Res 2003 Jun 8;92(11):1262-7. Epub 2003 May 8.

Department of Human Genetics, Gonda Genetics Research Center, of California, Los Angeles, Calif 90095, USA.

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http://dx.doi.org/10.1161/01.RES.0000075600.87675.16DOI Listing
June 2003

Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice.

Circulation 2002 Jul;106(4):484-90

Department of Medicine, University of California, Los Angeles 90095-1679, USA.

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http://dx.doi.org/10.1161/01.cir.0000023623.87083.4fDOI Listing
July 2002

Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parent.

Arterioscler Thromb Vasc Biol 2002 May;22(5):843-8

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles 90033, USA.

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http://dx.doi.org/10.1161/01.atv.0000015329.15481.e8DOI Listing
May 2002

Positional cloning of the combined hyperlipidemia gene Hyplip1.

Nat Genet 2002 Jan 20;30(1):110-6. Epub 2001 Dec 20.

Department of Medicine, University of California, Los Angeles, 47-123 CHS, UCLA School of Medicine, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ng811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846781PMC
January 2002

Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice.

Arterioscler Thromb Vasc Biol 2002 Jan;22(1):121-6

Mammalian Cell and Molecular Biology Laboratory, San Diego State University, San Diego, CA, USA.

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http://dx.doi.org/10.1161/hq0102.102588DOI Listing
January 2002