Lawrence Recht

Lawrence Recht

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Lawrence Recht

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A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.

PLoS One 2019 10;14(10):e0223558. Epub 2019 Oct 10.

Clinical and Translational Research Program, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Palo Alto, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223558PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786640PMC
March 2020

Macrophage exclusion after radiation therapy (MERT): A new and effective way to increase the therapeutic ratio of radiotherapy.

Radiother Oncol 2020 Mar 5;144:159-164. Epub 2019 Dec 5.

Department of Neurology, Stanford University School of Medicine, United States.

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http://dx.doi.org/10.1016/j.radonc.2019.11.020DOI Listing
March 2020

A Metabolic Therapy for Malignant Glioma Requires a Clinical Measure.

Curr Oncol Rep 2017 Nov 2;19(12):84. Epub 2017 Nov 2.

Department of Neurology & Neurological Sciences (LR), Stanford University School of Medicine, Palo Alto, CA, 94305, USA.

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http://dx.doi.org/10.1007/s11912-017-0637-yDOI Listing
November 2017

Optimizing bevacizumab dosing in glioblastoma: less is more.

J Neurooncol 2017 Oct 30;135(1):99-105. Epub 2017 Jun 30.

Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/s11060-017-2553-2DOI Listing
October 2017

The Promise of Targeting Macrophages in Cancer Therapy.

Clin Cancer Res 2017 07 24;23(13):3241-3250. Epub 2017 Mar 24.

Department of Medicine, Stanford University, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-3122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529121PMC
July 2017

Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O-Methylguanine-DNA Methyltransferase Biomarker Analyses.

J Clin Oncol 2017 Jan 5;35(3):343-351. Epub 2016 Dec 5.

Timothy Cloughesy, University of California, Los Angeles; Lawrence Recht, Stanford Cancer Center, Stanford; Carlos Bais, Thomas Sandmann, Jean-Marie Bruey, Hartmut Koeppen, Bo Liu, Wendy Verret, See-Chun Phan, and David S. Shames, Genentech, South San Francisco, CA; Tom Mikkelsen, Henry Ford Hospital, Detroit, MI; Gaetano Finocchiaro, Istituto Neurologico Carlo Besta, Milan; Alba A. Brandes, Azienda Unità Sanitaria Locale-Istituto di Ricovero e Cura a Carattere Scientifico Institute of Neurologic Sciences, Bologna, Italy; Cristóbal Belda-Iniesta, Centro Integral Oncológico Clara Campal, University Hospital HM Sanchinarro, Madrid; Estela Pineda, Hospital Clinic of Barcelona; Carmen Balana, Institut Català d'Oncologia Badalona Hospital Germans Trias I Pujol, Barcelona, Spain; Olivier L. Chinot, Aix-Marseille Université Assistance Publique-Hôpitaux de Marseille, Marseille, France; David R. Macdonald, London Health Sciences Centre, London, Ontario, Canada; Manfred Westphal, University Clinic Hamburg-Eppendorf, Hamburg, Germany; Kirsten Hopkins, Bristol Haematology and Oncology Centre, Bristol, United Kingdom; and Michael Weller, University Hospital Zurich, Zurich, Switzerland.

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http://ascopubs.org/doi/10.1200/JCO.2015.64.7685
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http://dx.doi.org/10.1200/JCO.2015.64.7685DOI Listing
January 2017

SDF-1 Blockade Enhances Anti-VEGF Therapy of Glioblastoma and Can Be Monitored by MRI.

Neoplasia 2017 01 7;19(1):1-7. Epub 2016 Dec 7.

Department of Radiation Oncology, Stanford University, A246, 1050A Arastradero Rd., Palo Alto, CA 94304-1334, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149063PMC
January 2017

Response of metastatic glioma to vemurafenib.

Neurooncol Pract 2016 Dec 22;3(4):268-271. Epub 2015 Nov 22.

Neuro Oncology, Stanford, California (L.R., R.P.T.); Neurology, Stanford, California (K.E.L., N.Z.); Neuropathology, Stanford University Medical Center, Palo Alto, California (J.L.Z., H.V.).

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http://dx.doi.org/10.1093/nop/npv054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657395PMC
December 2016

Bevacizumab for Treatment-Refractory Pain Control in Neurofibromatosis Patients.

Cureus 2016 Dec 18;8(12):e933. Epub 2016 Dec 18.

Department of Neurology, Stanford University School of Medicine.

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http://dx.doi.org/10.7759/cureus.933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249264PMC
December 2016

Glioblastoma Multiforme Recurrence: An Exploratory Study of (18)F FPPRGD2 PET/CT.

Radiology 2015 Nov 12;277(2):497-506. Epub 2015 May 12.

From the Division of Nuclear Medicine and Molecular Imaging (A.I., C.M., E.M.), Department of Radiology, Neuroradiology Section (G.Z., N.F.), Division of Neurosurgery (G.H., G.L.), and Division of Neuro Oncology (S.N., L.R.), Stanford University Medical Center, 300 Pasteur Dr, Room H-2200, Stanford, CA 94305; and Departments of Radiology, Bioengineering, Materials Science, and Engineering, Stanford University School of Medicine, Stanford, Calif (S.S.G.).

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http://dx.doi.org/10.1148/radiol.2015141550DOI Listing
November 2015

Central Nervous System Cancers, Version 1.2015.

J Natl Compr Canc Netw 2015 Oct;13(10):1191-202

From University of Alabama at Birmingham Comprehensive Cancer Center; City of Hope Comprehensive Cancer Center; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; Yale Cancer Center/Smilow Cancer Hospital; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The University of Texas MD Anderson Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; University of Washington/Seattle Cancer Care Alliance; Roswell Park Cancer Institute; Duke Cancer Institute; UC San Diego Moores Cancer Center; University of Michigan Comprehensive Cancer Center; Memorial Sloan Kettering Cancer Center; St. Jude Children's Research Hospital/University of Tennessee Health Science Center; Massachusetts General Hospital Cancer Center; American Brain Tumor Association; Vanderbilt-Ingram Cancer Center; Mayo Clinic Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Stanford Cancer Institute; Fred & Pamela Buffet Cancer Center; Huntsman Cancer Institute at the University of Utah; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; Moffitt Cancer Center; Fox Chase Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; National Comprehensive Cancer Network.

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http://www.jnccn.org/content/13/10/1191.full.pdf
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http://dx.doi.org/10.6004/jnccn.2015.0148DOI Listing
October 2015

Inflammatory Pseudotumors of the Skull Base: Meta-Analysis.

Otol Neurotol 2015 Sep;36(8):1432-8

*Departments of Otolaryngology-Head and Neck Surgery, †Neurosurgery, and ‡Pathology, Stanford University School of Medicine, Stanford, California; and §Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1097/MAO.0000000000000818DOI Listing
September 2015

A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.

Neuro Oncol 2015 Jun 13;17(6):854-61. Epub 2015 Jan 13.

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania (J.S.); The Neurological Institute of Columbia University, New York, New York (R.K.L.); Stanford Cancer Center, Stanford, California (L.D.R.); Duke University Medical Center, Durham, North Carolina (D.A.R., G.E.A., D.D.B., J.H.S.); Evanston Northwestern Healthcare, Evanston, Illinois (N.A.P.); University of Texas M.D. Anderson Cancer Center, Houston, Texas (M.D.G.); University of Washington School of Medicine, Seattle, Washington (M.M.M.); Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah (R.J.); Yale University School of Medicine, New Haven, Connecticut (J.M.B); University Hospital-Case Medical Center & Case Comprehensive Cancer Center, Cleveland, Ohio (A.S.); Scott Cruickshank & Associates, Inc., Santa Barbara, C alifornia (S.C.); Celldex Therapeutics, Inc., Hampton, New Jersey (J.A.G., T.K., T.A.D.); University of Texas M.D. Anderson Cancer Center, Houston, Texas (A.B.H.).

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http://dx.doi.org/10.1093/neuonc/nou348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483122PMC
June 2015

γ-Glutamyl transferase 7 is a novel regulator of glioblastoma growth.

BMC Cancer 2015 Apr 7;15:225. Epub 2015 Apr 7.

Department of Neurosurgery, Stanford University School of Medicine, Institute for Stem Cell Biology and Regenerative Medicine, 1201 Welch Rd P309, Stanford, CA, 94305-5487, USA.

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http://dx.doi.org/10.1186/s12885-015-1232-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393868PMC
April 2015

Treatment options for optic pathway gliomas.

Curr Treat Options Neurol 2015 Feb;17(2):333

Stanford University Hospital, 875 Blake Wilbur Drive, Stanford, CA, 94305, USA.

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http://link.springer.com/10.1007/s11940-014-0333-2
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http://dx.doi.org/10.1007/s11940-014-0333-2DOI Listing
February 2015

Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines.

J Natl Compr Canc Netw 2014 Nov;12(11):1517-23

From University of Alabama at Birmingham Comprehensive Cancer Center; City of Hope Comprehensive Cancer Center; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The University of Texas MD Anderson Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; University of Washington/Seattle Cancer Care Alliance; Memorial Sloan Kettering Cancer Center; Roswell Park Cancer Institute; Duke Cancer Institute; UC San Diego Moores Cancer Center; American Brain Tumor Association; University of Michigan Comprehensive Cancer Center; St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; Massachusetts General Hospital Cancer Center; Vanderbilt-Ingram Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Stanford Comprehensive Cancer Center; Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center; Huntsman Cancer Institute at the University of Utah; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; Moffitt Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; and National Comprehensive Cancer Network.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337873PMC
http://dx.doi.org/10.6004/jnccn.2014.0151DOI Listing
November 2014

Supratentorial low-grade diffuse astrocytoma: medical management.

Semin Oncol 2014 Aug 1;41(4):446-457. Epub 2014 Jul 1.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00937754140015
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http://dx.doi.org/10.1053/j.seminoncol.2014.06.013DOI Listing
August 2014

Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats.

Neuro Oncol 2014 Jan 10;16(1):21-8. Epub 2013 Dec 10.

Corresponding author: J. Martin Brown, PhD, Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, A246, 1050A Arastradero Rd, Palo Alto, CA 94304-1334.

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http://images.biomedsearch.com/24335554/not149.pdf?AWSAccess
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http://neuro-oncology.oxfordjournals.org/cgi/doi/10.1093/neu
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http://dx.doi.org/10.1093/neuonc/not149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870826PMC
January 2014

Visualization of rodent brain tumor angiogenesis and effects of antiangiogenic treatment using 3D ΔR2-μMRA.

Angiogenesis 2013 Oct 5;16(4):785-93. Epub 2013 Jun 5.

Institute of Biomedical Sciences, Academia Sinica, N123, 128 Sec. 2, Academia Road, Nankang, Taipei, 11529, Taiwan, ROC.

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http://dx.doi.org/10.1007/s10456-013-9355-8DOI Listing
October 2013

Alterations in cerebrospinal fluid proteins in a presymptomatic primary glioma model.

PLoS One 2012 19;7(11):e49724. Epub 2012 Nov 19.

Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049724PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501526PMC
May 2013

Simultaneous perfusion and permeability measurements using combined spin- and gradient-echo MRI.

J Cereb Blood Flow Metab 2013 May 6;33(5):732-43. Epub 2013 Mar 6.

Lucas Center, Department of Radiology, Stanford University, Stanford, California 94305-5488, USA.

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http://dx.doi.org/10.1038/jcbfm.2013.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652702PMC
May 2013

Steroid-sparing effect of corticorelin acetate in peritumoral cerebral edema is associated with improvement in steroid-induced myopathy.

J Clin Oncol 2013 Mar 4;31(9):1182-7. Epub 2013 Feb 4.

Department of Neurology, Advanced Medicine Clinic, Stanford University School of Medicine, 875 Blake Wilbur Dr, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1200/JCO.2012.43.9455DOI Listing
March 2013

Advances in the management of glioblastoma: the role of temozolomide and MGMT testing.

Clin Pharmacol 2013 27;5:1-9. Epub 2012 Dec 27.

Department of Neurological Sciences, Stanford University Hospital, Stanford, CA, USA.

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http://dx.doi.org/10.2147/CPAA.S26586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534290PMC
January 2013

Bevacizumab improves quality of life in patients with recurrent glioblastoma.

Chemother Res Pract 2011 2;2011:602812. Epub 2011 Oct 2.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.

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https://www.hindawi.com/archive/2011/602812/
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http://dx.doi.org/10.1155/2011/602812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263615PMC
August 2012

Chemerin158K protein is the dominant chemerin isoform in synovial and cerebrospinal fluids but not in plasma.

J Biol Chem 2011 Nov 19;286(45):39520-7. Epub 2011 Sep 19.

Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.258954
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http://dx.doi.org/10.1074/jbc.M111.258954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234775PMC
November 2011

Treatment and prophylaxis of hematologic malignancy in the central nervous system.

Curr Treat Options Neurol 2011 Aug;13(4):400-12

Stanford Cancer Center, 875 Blake Wilbur Drive CC2221, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/s11940-011-0128-7DOI Listing
August 2011

5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.

Int J Cancer 2011 May;128(9):2230-9

Department of Neurology and Clinical Neurosciences, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1002/ijc.25558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992079PMC
May 2011

Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy.

Nat Med 2011 Feb 16;17(2):223-8. Epub 2011 Jan 16.

James H. Clark Center for Biomedical Engineering & Sciences, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nm.2292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833825PMC
February 2011

Treatment and prevention of secondary CNS lymphoma.

Semin Neurol 2010 Jul 24;30(3):263-72. Epub 2010 Jun 24.

Department of Neurology, Stanford University Medical School, Stanford, California 94305, USA.

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http://dx.doi.org/10.1055/s-0030-1255222DOI Listing
July 2010

Gender disparity in the rate of partner abandonment in patients with serious medical illness.

Cancer 2009 Nov;115(22):5237-42

Department of Oncology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1002/cncr.24577DOI Listing
November 2009

The science of prevention: novel strategies for and new insights into central nervous system prophylaxis in patients with cancer.

Semin Oncol 2009 Aug;36(4 Suppl 2):S1

Penn State Hershey Medical Center, Hershey, PA, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2009.05.010DOI Listing
August 2009

Understanding the origins of gliomas and developing novel therapies: cerebrospinal fluid and subventricular zone interplay.

Semin Oncol 2009 Aug;36(4 Suppl 2):S17-24

Department of Neurosurgery, Penn State Hershey Medical Center, Hershey, PA 17033-0859, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2009.05.003DOI Listing
August 2009

Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice.

J Neurol Sci 2009 Jan 8;276(1-2):133-7. Epub 2008 Nov 8.

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1016/j.jns.2008.09.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650849PMC
January 2009

A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection.

J Neurosurg 2008 Apr;108(4):782-90

Department of Neurology, Stanford University Medical School, Stanford, California 94305, USA.

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http://thejns.org/doi/10.3171/JNS/2008/108/4/0782
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http://dx.doi.org/10.3171/JNS/2008/108/4/0782DOI Listing
April 2008

Optimizing therapy for patients with brain metastases.

Semin Oncol 2006 Jun;33(3):299-306

Department of Medical Oncology, Stanford University Medical School, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2006.03.005DOI Listing
June 2006

Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas.

J Clin Oncol 2006 Jan 19;24(2):274-87. Epub 2005 Dec 19.

Division of Oncology, Center for Clinical Sciences Research, Institute for Computational and Mathematical Engineering, Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305-5151, USA.

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http://dx.doi.org/10.1200/JCO.2005.02.9405DOI Listing
January 2006

Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas.

Cancer Res 2005 Oct;65(19):8679-89

Division of Oncology, Center for Clinical Sciences Research, Stanford University School of Medicine, Stanford, California 94305-5151, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-1204DOI Listing
October 2005

High-resolution genome-wide mapping of genetic alterations in human glial brain tumors.

Cancer Res 2005 May;65(10):4088-96

Division of Oncology, Center for Clinical Sciences Research, Stanford University School of Medicine, Stanford, California 94305-5151, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4229DOI Listing
May 2005

Differentiation prevents assessment of neural stem cell pluripotency after blastocyst injection.

Stem Cells 2004 ;22(4):600-8

Department of Neurology, University of Massachusetts Medical School, Worcester, USA.

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http://dx.doi.org/10.1634/stemcells.22-4-600DOI Listing
March 2005

Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure.

J Neurosurg 2005 Jan;102(1):98-108

Departments of Neurology, Neurosurgery, and Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://thejns.org/doi/10.3171/jns.2005.102.1.0098
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http://dx.doi.org/10.3171/jns.2005.102.1.0098DOI Listing
January 2005

Prevention and treatment of central nervous system involvement by non-Hodgkin's lymphoma: a review of the literature.

Semin Neurol 2004 Dec;24(4):395-404

Department of Medical Oncology, Stanford University Medical Center, 300 Pasteur Drive, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1055/s-2004-861534DOI Listing
December 2004

Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis.

Neurobiol Dis 2004 Apr;15(3):544-52

Department of Surgery (Neurosurgery), University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1016/j.nbd.2003.11.016DOI Listing
April 2004

Neurologic complications of hematologic neoplasms.

Neurol Clin 2003 Feb;21(1):87-105

Department of Neurology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1016/s0733-8619(02)00030-0DOI Listing
February 2003

Neural stem cells: the end of the beginning.

Authors:
Lawrence Recht

J Cell Biochem 2003 Jan;88(1):9-10

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1002/jcb.10407DOI Listing
January 2003

Neural stem cells and neuro-oncology: quo vadis?

J Cell Biochem 2003 Jan;88(1):11-9

Departments of Neurology and Surgery (Neurosurgery), University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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http://dx.doi.org/10.1002/jcb.10208DOI Listing
January 2003

Somatic plasticity of neural stem cells: fact or fancy?

J Cell Biochem 2003 Jan;88(1):51-6

Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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http://doi.wiley.com/10.1002/jcb.10314
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http://dx.doi.org/10.1002/jcb.10314DOI Listing
January 2003