Lawrence J Whalley

Lawrence J Whalley

Lawrence J Whalley

Lawrence J Whalley

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Increased diastolic blood pressure is associated with MRI biomarkers of dementia-related brain pathology in normative ageing.

Age Ageing 2018 01;47(1):95-100

Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.

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http://dx.doi.org/10.1093/ageing/afx102DOI Listing
January 2018

Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936.

Neurobiol Aging 2017 07 7;55:91-98. Epub 2017 Mar 7.

Aberdeen Biomedical Imaging Centre, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.02.019DOI Listing
July 2017

Are gender-specific approaches required to prevent dementia?

Maturitas 2016 10 1;92:7-8. Epub 2016 Jul 1.

Institute of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZH, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03785122163015
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http://dx.doi.org/10.1016/j.maturitas.2016.06.022DOI Listing
October 2016

Cerebral correlates of cognitive reserve.

Psychiatry Res Neuroimaging 2016 Jan 19;247:65-70. Epub 2015 Oct 19.

Aberdeen Biomedical Imaging Centre, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen AB25 2ZD, UK.

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http://dx.doi.org/10.1016/j.pscychresns.2015.10.012DOI Listing
January 2016

Polygenic risk for Alzheimer's disease is not associated with cognitive ability or cognitive aging in non-demented older people.

J Alzheimers Dis 2014 ;39(3):565-74

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK Department of Psychology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.3233/JAD-131058DOI Listing
October 2014

Early life socioeconomic circumstance and late life brain hyperintensities--a population based cohort study.

PLoS One 2014 18;9(2):e88969. Epub 2014 Feb 18.

Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom ; Department of Nuclear Medicine, NHS Grampian, Aberdeen, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088969PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928340PMC
October 2014

Structural brain complexity and cognitive decline in late life--a longitudinal study in the Aberdeen 1936 Birth Cohort.

Neuroimage 2014 Oct 30;100:558-63. Epub 2014 Jun 30.

Aberdeen Biomedical Imaging Centre, Lilian Sutton Building, University of Aberdeen, Foresterhill, AB25 2ZD Aberdeen, Scotland, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2014.06.054DOI Listing
October 2014

Homocysteine, antioxidant micronutrients and late onset dementia.

Eur J Nutr 2014 Feb 27;53(1):277-85. Epub 2013 Apr 27.

Institute of Applied Health Sciences, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, Scotland, AB25 2ZH, UK,

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http://dx.doi.org/10.1007/s00394-013-0526-6DOI Listing
February 2014

Genetic and environmental factors in late onset dementia: possible role for early parental death.

Int J Geriatr Psychiatry 2013 Jan 22;28(1):75-81. Epub 2012 Jul 22.

Institute of Applied Health Sciences, University of Aberdeen, UK.

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http://dx.doi.org/10.1002/gps.3792DOI Listing
January 2013

Depressive symptoms in late life and cerebrovascular disease: the importance of intelligence and lesion location.

Depress Anxiety 2013 Jan 16;30(1):77-84. Epub 2012 Nov 16.

Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, UK.

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http://dx.doi.org/10.1002/da.22022DOI Listing
January 2013

Openness to experience and activity engagement facilitate the maintenance of verbal ability in older adults.

Psychol Aging 2012 Dec 18;27(4):849-54. Epub 2012 Jun 18.

Department of Psychology, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1037/a0029066DOI Listing
December 2012

Anticholinergic drugs in late life: adverse effects on cognition but not on progress to dementia.

J Alzheimers Dis 2012 ;30(2):253-61

The Institute of Applied Health Sciences, Foresterhill, University of Aberdeen, Aberdeen, Scotland, UK.

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http://dx.doi.org/10.3233/JAD-2012-110935DOI Listing
September 2012

Brain structural complexity and life course cognitive change.

Neuroimage 2012 Jul 10;61(3):694-701. Epub 2012 Apr 10.

Aberdeen Biomedical Imaging Centre, Lilian Sutton Building, University of Aberdeen, Foresterhill, AB25 2ZD Aberdeen, Scotland, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S105381191200376
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http://dx.doi.org/10.1016/j.neuroimage.2012.03.088DOI Listing
July 2012

Spatial distribution and secular trends in the epidemiology of Alzheimer's disease.

Neuroimaging Clin N Am 2012 Feb;22(1):1-10, vii

Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Polwarth Building, Aberdeen AB25 2ZH, UK.

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http://dx.doi.org/10.1016/j.nic.2011.11.002DOI Listing
February 2012

The balance between cognitive reserve and brain imaging biomarkers of cerebrovascular and Alzheimer's diseases.

Brain 2011 Dec 18;134(Pt 12):3687-96. Epub 2011 Nov 18.

Aberdeen Biomedical Imaging Centre, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, UK.

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http://dx.doi.org/10.1093/brain/awr259DOI Listing
December 2011

Inter-individual differences in fMRI entropy measurements in old age.

IEEE Trans Biomed Eng 2011 Nov 22;58(11):3206-14. Epub 2011 Aug 22.

Aberdeen Biomedical Imaging Centre, SINAPSE Collaboration, University of Aberdeen, Aberdeen, Scotland, UK.

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http://dx.doi.org/10.1109/TBME.2011.2164793DOI Listing
November 2011

How useful are the SF-36 sub-scales in older people? Mokken scaling of data from the HALCyon programme.

Qual Life Res 2011 Sep 12;20(7):1005-10. Epub 2011 Jan 12.

MRC Unit for Lifelong Health and Ageing, University College London, 33, Bedford Place, London, WC1B 5JU, UK.

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http://dx.doi.org/10.1007/s11136-010-9838-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161183PMC
September 2011

Cerebellar brain volume accounts for variance in cognitive performance in older adults.

Cortex 2011 Apr 18;47(4):441-50. Epub 2010 Jan 18.

Department of Psychology, NUI, Galway, Ireland.

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http://dx.doi.org/10.1016/j.cortex.2010.01.001DOI Listing
April 2011

Caffeine, cognition, and socioeconomic status.

J Alzheimers Dis 2010 ;20 Suppl 1:S151-9

School of Medicine & Dentistry, Division of Applied Health Sciences, Foresterhill, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.3233/JAD-2010-1409DOI Listing
September 2010

Solvent exposure and cognitive ability at age 67: a follow-up study of the 1947 Scottish Mental Survey.

Occup Environ Med 2010 Jun 11;67(6):401-7. Epub 2009 Nov 11.

Environmental and Occupational Medicine, Population Health Section, Division of Applied Health Sciences, University of Aberdeen Medical School, Aberdeen, UK.

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http://dx.doi.org/10.1136/oem.2009.047977DOI Listing
June 2010

Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking.

PLoS One 2010 Jun 25;5(6):e11329. Epub 2010 Jun 25.

Nutrition and Epigenetics Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011329PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892514PMC
June 2010

Associations between childhood intelligence (IQ), adult morbidity and mortality.

Maturitas 2010 Feb 30;65(2):98-105. Epub 2009 Oct 30.

University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, Geriatric Medicine Unit, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.maturitas.2009.09.021DOI Listing
February 2010

Association of KIBRA and memory.

Neurosci Lett 2009 Jul 3;458(3):140-3. Epub 2009 May 3.

Department of Psychology, University of Edinburgh, 7 George Square, EH89JZ, Scotland, UK.

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http://dx.doi.org/10.1016/j.neulet.2009.04.050DOI Listing
July 2009

Genetic determinants of ageing processes and diseases in later life.

Maturitas 2009 Mar 8;62(3):225-9. Epub 2009 Feb 8.

Department of Medicine for the Elderly, Woodend Hospital, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1016/j.maturitas.2008.12.012DOI Listing
March 2009

Predictors and correlates of edentulism in the healthy old people in Edinburgh (HOPE) study.

Gerodontology 2008 Dec 15;25(4):199-204. Epub 2008 Apr 15.

Geriatric Medicine Unit, University of Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1111/j.1741-2358.2008.00227.xDOI Listing
December 2008

GSTz1 genotype and cognitive ability.

Psychiatr Genet 2008 Aug;18(4):211-2

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http://dx.doi.org/10.1097/YPG.0b013e328304dea8DOI Listing
August 2008

Blood pressure and cognition in the Aberdeen 1936 birth cohort.

Gerontology 2007 28;53(6):432-7. Epub 2007 Nov 28.

University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1159/000111696DOI Listing
July 2008

PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes.

Neurosci Lett 2008 Mar 17;434(1):50-5. Epub 2008 Jan 17.

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.neulet.2008.01.027DOI Listing
March 2008

Quality of life and its correlates in octogenarians. Use of the SEIQoL-DW in Wave 5 of the Aberdeen Birth Cohort 1921 Study (ABC1921).

Qual Life Res 2008 Feb 11;17(1):11-20. Epub 2007 Dec 11.

Department of Medicine and Therapeutics, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://link.springer.com/10.1007/s11136-007-9291-4
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http://dx.doi.org/10.1007/s11136-007-9291-4DOI Listing
February 2008

n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: an observational follow-up study in late adulthood.

Am J Clin Nutr 2008 Feb;87(2):449-54

Department of Environmental and Occupational Medicine, University of Aberdeen, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/87.2.449DOI Listing
February 2008

Predictors of tooth loss in the 1921 Lothian Birth Cohort.

Age Ageing 2008 Jan 21;37(1):111-4. Epub 2007 Nov 21.

Geriatric Medicine Unit, University of Edinburgh, Royal Victoria Hospital, Edinburgh, EH4 2DN, UK.

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http://dx.doi.org/10.1093/ageing/afm160DOI Listing
January 2008

Association between telomere length and heart disease in a narrow age cohort of older people.

Exp Gerontol 2007 Jun 20;42(6):571-3. Epub 2006 Dec 20.

Geriatric Medicine Unit, University of Edinburgh, The Royal Victoria Hospital, Craigleith Road, Edinburgh, Scotland, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S05315565060045
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http://dx.doi.org/10.1016/j.exger.2006.12.002DOI Listing
June 2007

No association of CETP genotype with cognitive function or age-related cognitive change.

Neurosci Lett 2007 Jun 10;420(2):189-92. Epub 2007 May 10.

Department of Psychology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neulet.2007.05.013DOI Listing
June 2007

COMT genotype and cognitive ability: a longitudinal aging study.

Neurosci Lett 2007 Jun 21;421(1):57-61. Epub 2007 May 21.

Department of Geriatric Medicine, Royal Victoria Hospital, Craigleith Road, Edinburgh EH4 2DN, UK.

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http://dx.doi.org/10.1016/j.neulet.2007.05.023DOI Listing
June 2007

Smoking and cognitive change from age 11 to 66 years: a confirmatory investigation.

Addict Behav 2007 Jan 2;32(1):63-8. Epub 2006 May 2.

Department of Geriatric Medicine, University of Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.addbeh.2006.03.020DOI Listing
January 2007

The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people.

Neurosci Lett 2006 Oct 21;406(3):260-4. Epub 2006 Aug 21.

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neulet.2006.07.055DOI Listing
October 2006

Physical fitness and lifetime cognitive change.

Neurology 2006 Oct;67(7):1195-200

Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1212/01.wnl.0000238520.06958.6aDOI Listing
October 2006

Generality and specificity in cognitive aging: a volumetric brain analysis.

Neuroimage 2006 May 10;30(4):1433-40. Epub 2006 Jan 10.

Department of Bio-medical Physics, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZD, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2005.11.004DOI Listing
May 2006

Commentary: childhood education and disparities in adult health--the need for improved theories and better data.

Int J Epidemiol 2006 Apr 22;35(2):466-7. Epub 2006 Mar 22.

Department of Mental Health, Institute of Applied Health Sciences, University of Aberdeen, Forresterhill, Aberdeen, AB25 2ZH, UK.

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http://dx.doi.org/10.1093/ije/dyl040DOI Listing
April 2006

A life-course approach to the aetiology of late-onset dementias.

Lancet Neurol 2006 Jan;5(1):87-96

Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1016/S1474-4422(05)70286-6DOI Listing
January 2006

Brain white matter hyperintensities: relative importance of vascular risk factors in nondemented elderly people.

Radiology 2005 Oct 26;237(1):251-7. Epub 2005 Aug 26.

Department of Radiology, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland.

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http://dx.doi.org/10.1148/radiol.2371041496DOI Listing
October 2005

Genetic influences on oxidative stress and their association with normal cognitive ageing.

Neurosci Lett 2005 Sep;386(2):116-20

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.neulet.2005.05.067DOI Listing
September 2005

Large, consistent estimates of the heritability of cognitive ability in two entire populations of 11-year-old twins from Scottish mental surveys of 1932 and 1947.

Behav Genet 2005 Sep;35(5):525-34

School of Biological Sciences, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, EH9 3JT, UK.

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http://dx.doi.org/10.1007/s10519-005-3556-xDOI Listing
September 2005

The cognitive cost of being a twin: two whole-population surveys.

Twin Res Hum Genet 2005 Aug;8(4):376-83

Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1375/1832427054936709DOI Listing
August 2005

KLOTHO genotype and cognitive ability in childhood and old age in the same individuals.

Neurosci Lett 2005 Apr 22;378(1):22-7. Epub 2005 Jan 22.

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.neulet.2004.12.005DOI Listing
April 2005

Differential cognitive outcomes in the Hypertensive Old People in Edinburgh study.

J Neurol Sci 2005 Mar 16;229-230:103-7. Epub 2004 Dec 16.

Geriatric Medicine unit, Edinburgh University, United Kingdom.

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http://dx.doi.org/10.1016/j.jns.2004.11.005DOI Listing
March 2005

Childhood IQ, smoking, and cognitive change from age 11 to 64 years.

Addict Behav 2005 Jan;30(1):77-88

Department of Mental Health, University of Aberdeen, Aberdeen, Scotland, UK.

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http://dx.doi.org/10.1016/j.addbeh.2004.04.014DOI Listing
January 2005

Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing.

Neurosci Lett 2005 Jan;373(2):110-4

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH89JZ, UK.

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http://dx.doi.org/10.1016/j.neulet.2004.09.073DOI Listing
January 2005

Enhanced hippocampal long-term potentiation in rats after chronic exposure to homocysteine.

Neurosci Lett 2005 Jan;373(2):119-24

School of Medical Sciences, College of Life Sciences and Medicine, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK.

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http://dx.doi.org/10.1016/j.neulet.2004.09.072DOI Listing
January 2005

Cognitive aging, childhood intelligence, and the use of food supplements: possible involvement of n-3 fatty acids.

Am J Clin Nutr 2004 Dec;80(6):1650-7

University of Aberdeen, Department of Mental Health, Royal Cornhill Hospital, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/80.6.1650DOI Listing
December 2004

Cognitive reserve and the neurobiology of cognitive aging.

Ageing Res Rev 2004 Nov;3(4):369-82

Clinical Research Centre, School of Medicine, University of Aberdeen, Royal Cornhill Hospital, Cornhill Road, Aberdeen AB25 2ZH, UK.

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http://dx.doi.org/10.1016/j.arr.2004.05.001DOI Listing
November 2004

Age at natural menopause and cognition.

Maturitas 2004 Oct;49(2):148-56

Department of Mental Health, Aberdeen University, Royal Cornhill Hospital, Cornhill Road, Aberdeen AB25 2ZH, UK.

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http://dx.doi.org/10.1016/j.maturitas.2003.12.014DOI Listing
October 2004

Diet and dementia.

J Br Menopause Soc 2004 Sep;10(3):113-7

Department of Mental Health, School of Medicine, University of Aberdeen, UK.

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http://dx.doi.org/10.1258/1362180043654575DOI Listing
September 2004

What provides cerebral reserve?

Brain 2004 May 26;127(Pt 5):1191-9. Epub 2004 Mar 26.

Department of Bio-Medical Physics and Bioengineering, University of Aberdeen and Aberdeen Royal Infirmary, Foresterhill, UK.

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http://dx.doi.org/10.1093/brain/awh144DOI Listing
May 2004

Searching for genetic influences on normal cognitive ageing.

Trends Cogn Sci 2004 Apr;8(4):178-84

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.tics.2004.02.008DOI Listing
April 2004

Life long changes in cognitive ability are associated with prescribed medications in old age.

Int J Geriatr Psychiatry 2004 Apr;19(4):327-32

Geriatric Medicine Unit, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/gps.1093DOI Listing
April 2004

The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947.

J Pers Soc Psychol 2004 Jan;86(1):130-47

Department of Psychology, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1037/0022-3514.86.1.130DOI Listing
January 2004

Quality of Life in healthy old age: relationships with childhood IQ, minor psychological symptoms and optimism.

Soc Psychiatry Psychiatr Epidemiol 2003 Nov;38(11):632-6

The Medical School, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1007/s00127-003-0685-5DOI Listing
November 2003

Brain ageing and dementia: what makes the difference?

Br J Psychiatry 2002 Nov;181:369-71

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http://dx.doi.org/10.1192/bjp.181.5.369DOI Listing
November 2002

Cognitive change and the APOE epsilon 4 allele.

Nature 2002 Aug;418(6901):932

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1038/418932aDOI Listing
August 2002

Homocysteine, B vitamin status, and cognitive function in the elderly.

Am J Clin Nutr 2002 May;75(5):908-13

Rowett Research Institute, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/75.5.908DOI Listing
May 2002