Lawrence J Abraham

Lawrence J Abraham

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Lawrence J Abraham

Lawrence J Abraham

Publications by authors named "Lawrence J Abraham"

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Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes.

J Hypertens 2019 May;37(5):997-1011

The Curtin/UWA Centre for Genetic Origins of Health and Disease, School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University.

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http://dx.doi.org/10.1097/HJH.0000000000002023DOI Listing
May 2019

Finding potential cis-regulatory loci using allele-specific chromatin accessibility as weights in a kernel-based variance component test.

BMC Proc 2016 18;10(Suppl 7):103-108. Epub 2016 Oct 18.

South Texas Diabetes and Obesity Institute, University of Texas at the Rio Grande Valley, One West University Blvd., Brownsville, TX 78520 USA ; South Texas Diabetes and Obesity Institute, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 USA.

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http://dx.doi.org/10.1186/s12919-016-0013-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133489PMC
October 2016

Identification of a thalidomide derivative that selectively targets tumorigenic liver progenitor cells and comparing its effects with lenalidomide and sorafenib.

Eur J Med Chem 2016 Sep 9;120:275-83. Epub 2016 Mar 9.

School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA 6009, Australia; The Centre for Medical Research, The Perkins Institute of Medical Research, Nedlands, WA 6009, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.03.015DOI Listing
September 2016

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells.

Cell Mol Immunol 2016 Jan 2;13(1):119-31. Epub 2015 Feb 2.

School of Pathology and Laboratory Medicine, Centre for Genetic Origins of Health and Disease, The University of Western Australia, Crawley, WA, Australia.

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http://www.nature.com/articles/cmi2014138
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http://dx.doi.org/10.1038/cmi.2014.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711682PMC
January 2016

Analysis of tandem E-box motifs within human Complement receptor 2 (CR2/CD21) promoter reveals cell specific roles for RP58, E2A, USF and localized chromatin accessibility.

Int J Biochem Cell Biol 2015 Jul 27;64:107-19. Epub 2015 Mar 27.

School of Pathology and Laboratory Medicine, Centre for Genetic Origins of Health and Disease, The University of Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2015.03.016DOI Listing
July 2015

MACROD2 gene associated with autistic-like traits in a general population sample.

Psychiatr Genet 2014 Dec;24(6):241-248

Centre for Genetic Origins of Health and Disease, Telethon Institute for Child Health Research, University of Western Australia, Perth, Australia.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/YPG.0000000000000052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320645PMC
December 2014

Molecular prioritization strategies to identify functional genetic variants in the cardiovascular disease-associated expression QTL Vanin-1.

Eur J Hum Genet 2014 May 18;22(5):688-95. Epub 2013 Sep 18.

1] School of Chemistry and Biochemistry, University of Western Australia, Crawley, WA, Australia [2] Centre for Genetic Origins of Health and Disease (GOHaD), University of Western Australia, Crawley, WA, Australia.

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http://www.nature.com/articles/ejhg2013208
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http://dx.doi.org/10.1038/ejhg.2013.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992570PMC
May 2014

Ethynylbenzenoid metabolites of Antrodia camphorata: synthesis and inhibition of TNF expression.

Org Biomol Chem 2014 Feb;12(7):1100-13

School of Chemistry and Biochemistry, The University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1039/c3ob42333fDOI Listing
February 2014

Genome-wide association study of autistic-like traits in a general population study of young adults.

Front Hum Neurosci 2013 11;7:658. Epub 2013 Oct 11.

Centre for Genetic Origins of Health and Disease, University of Western Australia , Perth, WA , Australia.

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http://dx.doi.org/10.3389/fnhum.2013.00658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795398PMC
October 2013

TNF-inducible expression of lymphotoxin-β in hepatic cells: an essential role for NF-κB and Ets1 transcription factors.

Cytokine 2012 Nov 26;60(2):498-504. Epub 2012 Jun 26.

Biochemistry and Molecular Biology, School of Chemistry and Biochemistry, The University of Western Australia, Crawley 6009, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S104346661200243
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http://dx.doi.org/10.1016/j.cyto.2012.05.029DOI Listing
November 2012

Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases.

Biochem Biophys Res Commun 2012 Jan 1;417(2):653-8. Epub 2011 Dec 1.

School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1102120
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http://dx.doi.org/10.1016/j.bbrc.2011.11.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259148PMC
January 2012

Efforts toward elucidating Thalidomide's molecular target: an expedient synthesis of the first Thalidomide biotin analogue.

Org Biomol Chem 2010 Sep 13;8(18):4059-62. Epub 2010 Jul 13.

School of Biomedical, Biomolecular and Chemical Science, University of Western Australia, 35 Stirling Hwy, Crawley, 6009, WA, Australia.

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http://dx.doi.org/10.1039/c0ob00060dDOI Listing
September 2010

New thalidomide analogues derived through Sonogashira or Suzuki reactions and their TNF expression inhibition profiles.

Bioorg Med Chem 2010 Jan 6;18(2):650-62. Epub 2009 Dec 6.

The School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia Crawley, WA 6009, Australia.

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http://dx.doi.org/10.1016/j.bmc.2009.12.001DOI Listing
January 2010

Bone marrow cells play only a very minor role in chronic liver regeneration induced by a choline-deficient, ethionine-supplemented diet.

Stem Cell Res 2008 Sep 3;1(3):195-204. Epub 2008 Jun 3.

Western Australian Institute for Medical Research, Centre for Medical Research, Perth, WA, Australia.

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http://dx.doi.org/10.1016/j.scr.2008.05.004DOI Listing
September 2008

Genetic association of preeclampsia to the inflammatory response gene SEPS1.

Am J Obstet Gynecol 2008 Mar 20;198(3):336.e1-5. Epub 2008 Feb 20.

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1016/j.ajog.2007.09.024DOI Listing
March 2008

Quantitative differences in chromatin accessibility across regulatory regions can be directly compared in distinct cell-types.

Biochem Biophys Res Commun 2008 Mar 27;367(2):349-55. Epub 2007 Dec 27.

Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, 6009 WA, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2007.12.121DOI Listing
March 2008

Synthesis and TNF expression inhibitory properties of new thalidomide analogues derived via Heck cross coupling.

Bioorg Med Chem Lett 2007 Nov 25;17(21):5819-24. Epub 2007 Aug 25.

The School of Biomedical, Biomolecular & Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia.

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http://dx.doi.org/10.1016/j.bmcl.2007.08.042DOI Listing
November 2007

Integration site-specific transcriptional reporter gene analysis using Flp recombinase targeted cell lines.

Biotechniques 2007 Feb;42(2):217-24

University of Western Australia, Crawley, WA, Australia.

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http://dx.doi.org/10.2144/000112317DOI Listing
February 2007

Attenuated liver progenitor (oval) cell and fibrogenic responses to the choline deficient, ethionine supplemented diet in the BALB/c inbred strain of mice.

J Hepatol 2007 Jan 9;46(1):134-41. Epub 2006 Oct 9.

School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, Alma Rd., Fremantle, WA 6101, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S016882780600500
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http://dx.doi.org/10.1016/j.jhep.2006.08.015DOI Listing
January 2007

Hepatic expression of the tumor necrosis factor family member lymphotoxin-beta is regulated by interleukin (IL)-6 and IL-1beta: transcriptional control mechanisms in oval cells and hepatoma cell lines.

Liver Int 2005 Jun;25(3):633-46

Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, The University of Western Australia, Crawley, Western Australia, Australia.

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http://dx.doi.org/10.1111/j.1478-3231.2005.01080.xDOI Listing
June 2005

Polymorphism of the CD30 promoter microsatellite repressive element is associated with development of primary cutaneous lymphoproliferative disorders.

Cancer Epidemiol Biomarkers Prev 2005 May;14(5):1322-5

The Western Australian Institute for Medical Research and Centre for Medical Research, The University of Western Australia, Level 6, MRF Building, 50 Rear Murray Street, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1158/1055-9965.EPI-04-0826DOI Listing
May 2005

Differential lymphotoxin-beta and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury.

Hepatology 2005 Feb;41(2):327-35

School of Biomedical and Chemical Sciences, The University of Western Australia, Crawley, Australia.

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http://doi.wiley.com/10.1002/hep.20520
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http://dx.doi.org/10.1002/hep.20520DOI Listing
February 2005

TNF and phorbol esters induce lymphotoxin-beta expression through distinct pathways involving Ets and NF-kappa B family members.

J Immunol 2004 Apr;172(7):4332-41

Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences and the Center for Medical Research, University of Western Australia, Crawley, Western Australia, Australia.

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http://dx.doi.org/10.4049/jimmunol.172.7.4332DOI Listing
April 2004

Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).

Nucleic Acids Res 2003 Oct;31(19):5483-9

Integrated Department of Immunology, National Jewish Medical and Research Center and University of Colorado Health Sciences Center, Denver, CO 80262, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC206479PMC
http://dx.doi.org/10.1093/nar/gkg785DOI Listing
October 2003

Oval cell-mediated liver regeneration: Role of cytokines and growth factors.

J Gastroenterol Hepatol 2003 Jan;18(1):4-12

Western Australian Institute for Medical Research, School of Biomedical and Chemical Sciences, The University of Western Australia, Crawley, Australia.

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http://dx.doi.org/10.1046/j.1440-1746.2003.02906.xDOI Listing
January 2003

A proteomics approach for the identification of DNA binding activities observed in the electrophoretic mobility shift assay.

Mol Cell Proteomics 2002 Jun;1(6):472-8

Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences and Western Australian Institute for Medical Research, The University of Western Australia, Crawley 6009, Australia.

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http://dx.doi.org/10.1074/mcp.t200003-mcp200DOI Listing
June 2002