Lawrence Chan

Lawrence Chan

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The applications of big data in molecular diagnostics.

Expert Rev Mol Diagn 2019 10 29;19(10):905-917. Epub 2019 Aug 29.

Department of Health Technology and Informatics, Hong Kong Polytechnic University , Hong Kong Special Administrative Region.

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http://dx.doi.org/10.1080/14737159.2019.1657834DOI Listing
October 2019

The applications of metabolomics in the molecular diagnostics of cancer.

Expert Rev Mol Diagn 2019 Sep 21;19(9):785-793. Epub 2019 Aug 21.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University , Kowloon , Hong Kong Special Administrative Region , China.

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http://dx.doi.org/10.1080/14737159.2019.1656530DOI Listing
September 2019

Association Patterns of Ontological Features Signify Electronic Health Records in Liver Cancer.

J Healthc Eng 2017 6;2017:6493016. Epub 2017 Aug 6.

Department of Diagnostic Radiology, University of Hong Kong, Pok Fu Lam, Hong Kong.

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http://dx.doi.org/10.1155/2017/6493016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563431PMC
July 2019

Spinal Ewing Sarcoma Metastatic to Bilateral Orbits.

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):e206-e208

Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut.

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http://Insights.ovid.com/crossref?an=00002341-900000000-9840
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http://dx.doi.org/10.1097/IOP.0000000000001249DOI Listing
May 2019

Magnetic Foreign Body Ingestion in Children: The Attractive Hazards.

Case Rep Pediatr 2019 28;2019:3549242. Epub 2019 Apr 28.

Department of Pediatrics, The University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1155/2019/3549242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512031PMC
April 2019

IL-4 dysregulates microRNAs involved in inflammation, angiogenesis and apoptosis in epidermal keratinocytes.

Microbiol Immunol 2018 Nov;62(11):732-736

Department of Dermatology, University of Illinois, 808 S Wood St., Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1111/1348-0421.12650DOI Listing
November 2018

Multi-scale representation of proteomic data exhibits distinct microRNA regulatory modules in non-smoking female patients with lung adenocarcinoma.

Comput Biol Med 2018 11 12;102:51-56. Epub 2018 Sep 12.

Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00104825183026
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http://dx.doi.org/10.1016/j.compbiomed.2018.09.005DOI Listing
November 2018

Gene therapy for neuropathic pain using dorsal root ganglion-targeted helper-dependent adenoviral vectors with GAD67 expression.

Pain Rep 2018 Nov 15;3(6):e695. Epub 2018 Oct 15.

Department of Stem Cell Biology and Regenerative Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan.

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http://dx.doi.org/10.1097/PR9.0000000000000695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344132PMC
November 2018

Oxygen Saturation and Heart Rate Variations as Predictors of Intradialytic Hypotension.

Nephrol Nurs J 2018 Jan-Feb;45(1):53-60

Chair Professor, Department of Health & Physical Education, The Education University of Hong Kong, Hong Kong.

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August 2018

Implementation and new insights in molecular diagnostics for HIV infection.

Expert Rev Mol Diagn 2018 05 19;18(5):433-441. Epub 2018 Apr 19.

a Department of Health Technology and Informatics, Faculty of Health and Social Sciences , The Hong Kong Polytechnic University , Kowloon , Hong Kong Special Administrative Region , China.

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http://dx.doi.org/10.1080/14737159.2018.1464393DOI Listing
May 2018

Hotspot exon 2 mutations in CD166 positive colorectal cancer and colorectal adenoma cells.

Oncotarget 2018 04 17;9(29):20426-20438. Epub 2018 Apr 17.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region.

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http://dx.doi.org/10.18632/oncotarget.24921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945530PMC
April 2018

Vector-model-supported optimization in volumetric-modulated arc stereotactic radiotherapy planning for brain metastasis.

Med Dosim 2017 Summer;42(2):85-89. Epub 2017 Mar 18.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.meddos.2017.01.002DOI Listing
March 2018

Vector-model-supported approach in prostate plan optimization.

Med Dosim 2017 Summer;42(2):79-84. Epub 2017 Mar 18.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.meddos.2017.01.001DOI Listing
March 2018

Yoga training modulates adipokines in adults with high-normal blood pressure and metabolic syndrome.

Scand J Med Sci Sports 2018 Mar 7;28(3):1130-1138. Epub 2018 Feb 7.

School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1111/sms.13029DOI Listing
March 2018

Adipokine Profiling in Adult Women With Central Obesity and Hypertension.

Front Physiol 2018 27;9:294. Epub 2018 Mar 27.

School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.3389/fphys.2018.00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881161PMC
March 2018

Unusually extensive scalp ulcerations manifested in pemphigus erythematosus.

Dermatol Online J 2018 Jan 15;24(1). Epub 2018 Jan 15.

University of Illinois College of Medicine, Chicago, Illinois.

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January 2018

Genome Surgery and Gene Therapy in Retinal Disorders.

Yale J Biol Med 2017 12 19;90(4):523-532. Epub 2017 Dec 19.

Jonas Children's Vision Care, and Bernard & Shirlee Brown Glaucoma Laboratory, Department of Ophthalmology, Columbia University Medical Center, New York, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733860PMC
December 2017

Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity.

Mol Metab 2017 11 1;6(11):1350-1359. Epub 2017 Sep 1.

School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325000, China; USDA-ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Division of Diabetes, Endocrinology & Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681239PMC
November 2017

Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice.

Mol Metab 2017 11 18;6(11):1381-1394. Epub 2017 Jul 18.

Department of Physiology, Monash University, Clayton, Victoria, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia; Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778173005
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http://dx.doi.org/10.1016/j.molmet.2017.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681238PMC
November 2017

Editorial: Cancer Diagnostic and Therapeutic Target Identification and Verification Based on the Regulatory Functions of MicroRNAs.

Front Genet 2017 15;8:178. Epub 2017 Nov 15.

Department of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong.

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http://dx.doi.org/10.3389/fgene.2017.00178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694744PMC
November 2017

Anti-TCRβ mAb in Combination With Neurogenin3 Gene Therapy Reverses Established Overt Type 1 Diabetes in Female NOD Mice.

Endocrinology 2017 10;158(10):3140-3151

Center for Immunobiology and Transplantation Research, Department of Surgery, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas 77030.

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http://dx.doi.org/10.1210/en.2016-1947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659705PMC
October 2017

Adiponectin is required for maintaining normal body temperature in a cold environment.

BMC Physiol 2017 Oct 23;17(1). Epub 2017 Oct 23.

USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s12899-017-0034-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651620PMC
October 2017

Irregular erythematous patch on the face of an infant.

Cutis 2017 Oct;100(4):E4-E6

Medical Service, Jesse Brown VA Medical Center, Chicago; and the Department of Dermatology, University of Illinois, Chicago, USA.

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October 2017

Inhibition of Miro1 disturbs mitophagy and pancreatic β-cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes.

Oncotarget 2017 Oct 16;8(53):90693-90705. Epub 2017 Sep 16.

ABSL-3 Laboratory at the Center for Animal Experiment and Institute of Animal Model for Human Disease, Wuhan University School of Medicine, Wuhan, P. R. China.

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http://dx.doi.org/10.18632/oncotarget.20963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710878PMC
October 2017

Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells.

PLoS One 2017 21;12(3):e0173981. Epub 2017 Mar 21.

Department of Dermatology, University of Illinois at Chicago (UIC)-College of Medicine, Chicago, IL, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173981PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360272PMC
September 2017

The constitutive lipid droplet protein PLIN2 regulates autophagy in liver.

Autophagy 2017 Jul 26;13(7):1130-1144. Epub 2017 May 26.

a Departments of Medicine, Baylor College of Medicine , Houston , TX , USA.

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http://dx.doi.org/10.1080/15548627.2017.1319544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529083PMC
July 2017

Loss of glutaredoxin 3 impedes mammary lobuloalveolar development during pregnancy and lactation.

Am J Physiol Endocrinol Metab 2017 03 15;312(3):E136-E149. Epub 2016 Nov 15.

USDA/ARS Children Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas;

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http://dx.doi.org/10.1152/ajpendo.00150.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374299PMC
March 2017

Long-term outcome of expanded newborn screening at Boston children's hospital: benefits and challenges in defining true disease.

J Inherit Metab Dis 2017 03 4;40(2):209-218. Epub 2017 Jan 4.

Division of Genetics and Genomics, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, 1 Autumn Street, Rm 526.1, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s10545-016-0004-4DOI Listing
March 2017

Paraneoplastic Pemphigus and Autoimmune Blistering Diseases Associated with Neoplasm: Characteristics, Diagnosis, Associated Neoplasms, Proposed Pathogenesis, Treatment.

Am J Clin Dermatol 2017 Feb;18(1):105-126

Department of Dermatology, University of Illinois College of Medicine, UIC-Derm, MC624, 808 S. Wood Street, R380, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1007/s40257-016-0235-zDOI Listing
February 2017

Pathway analysis of complex diseases for GWAS, extending to consider rare variants, multi-omics and interactions.

Biochim Biophys Acta Gen Subj 2017 Feb 23;1861(2):335-353. Epub 2016 Nov 23.

Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, China.

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https://linkinghub.elsevier.com/retrieve/pii/S03044165163045
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http://dx.doi.org/10.1016/j.bbagen.2016.11.030DOI Listing
February 2017

Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial.

Transplantation 2017 Jan;101(1):157-165

1 School of Medicine, University of Maryland, Baltimore, MD. 2 Emory University, Atlanta, GA. 3 Henry Ford Hospital, Detroit, MI. 4 California Pacific Medical Center, San Francisco, CA. 5 University of Iowa, Iowa City, IA. 6 Stanford University, Palo Alto, CA. 7 University of Colorado, Denver, CO. 8 Medical University of South Carolina, Charleston, SC. 9 Baylor University Medical Center, Dallas, TX. 10 St. Barnabas Medical Center, Newark, NJ. 11 University of Kentucky, Lexington, KY. 12 Vanderbilt University Medical Center, Nashville, TN. 13 Our Lady of Lourdes Medical Center, Camden, NJ. 14 CTI Clinical Trial and Consulting Services, Cincinatti, OH.

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http://dx.doi.org/10.1097/TP.0000000000001098DOI Listing
January 2017

Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.

Endocrinology 2017 01;158(1):9-20

Diabetes and Endocrinology Research Center, Division of Diabetes, Endocrinology, and Metabolism, Departments of Medicine, Molecular and Cellular Biology, Biochemistry and Molecular Biology, and Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2016-1541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412984PMC
January 2017

A case report of iatrogenic cutaneous Kaposi sarcoma due to rituximab therapy for thrombotic thrombocytopenic purpura.

Acta Oncol 2017 Jan 25;56(1):111-113. Epub 2016 Nov 25.

a Department of Dermatology , University of Illinois at Chicago , Illinois , USA.

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http://dx.doi.org/10.1080/0284186X.2016.1253867DOI Listing
January 2017

PLIN2 is a Key Regulator of the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic β Cells.

Sci Rep 2017 01 19;7:40855. Epub 2017 Jan 19.

Department of Molecular &Cellular Biology, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1038/srep40855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244387PMC
January 2017

Cholesterol Accumulation in CD11c Immune Cells Is a Causal and Targetable Factor in Autoimmune Disease.

Immunity 2016 12;45(6):1311-1326

Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181791PMC
December 2016

Circulating Plasma MicroRNAs As Diagnostic Markers for NSCLC.

Front Genet 2016 3;7:193. Epub 2016 Nov 3.

Department of Health Technology and Informatics, Hong Kong Polytechnic University Hong Kong, Hong Kong.

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http://dx.doi.org/10.3389/fgene.2016.00193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093122PMC
November 2016

MiR-30a-5p Overexpression May Overcome EGFR-Inhibitor Resistance through Regulating PI3K/AKT Signaling Pathway in Non-small Cell Lung Cancer Cell Lines.

Front Genet 2016 15;7:197. Epub 2016 Nov 15.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University Hong Kong, China.

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http://dx.doi.org/10.3389/fgene.2016.00197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108768PMC
November 2016

Outcome of Encephalitis in Pediatric Intensive Care Unit.

Indian J Pediatr 2016 Oct 7;83(10):1098-103. Epub 2016 Apr 7.

Division of Critical Care Medicine, Nicklaus Childrens Hospital, Miami, FL, USA.

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http://dx.doi.org/10.1007/s12098-016-2068-4DOI Listing
October 2016

Solving the VA Physician Shortage Problem: The Right Thing to Do.

Authors:
Lawrence S Chan

Fed Pract 2016 Oct;33(10):8-11

is an attending physician at the Jesse Brown VAMC and at the Captain James A. Lovell Federal Health Care Center, both in Chicago, Illinois. He also is the Dr. Orville J. Stone Professor of Dermatology and head of the dermatology department at the University of Illinois in Chicago.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373710PMC
October 2016

Associations of mRNA:microRNA for the Shared Downstream Molecules of EGFR and Alternative Tyrosine Kinase Receptors in Non-small Cell Lung Cancer.

Front Genet 2016 13;7:173. Epub 2016 Oct 13.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University Hong Kong, Hong Kong.

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http://dx.doi.org/10.3389/fgene.2016.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061729PMC
October 2016

Doxorubicin Induces Inflammatory Modulation and Metabolic Dysregulation in Diabetic Skeletal Muscle.

Front Physiol 2016 27;7:323. Epub 2016 Jul 27.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University Hong Kong, China.

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http://dx.doi.org/10.3389/fphys.2016.00323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961708PMC
August 2016

S100A8 and S100A9 Are Associated with Doxorubicin-Induced Cardiotoxicity in the Heart of Diabetic Mice.

Front Physiol 2016 5;7:334. Epub 2016 Aug 5.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, Hong Kong Polytechnic University Hong Kong, China.

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http://dx.doi.org/10.3389/fphys.2016.00334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974484PMC
August 2016

Aberrant Wound Healing in an Epidermal Interleukin-4 Transgenic Mouse Model of Atopic Dermatitis.

PLoS One 2016 11;11(1):e0146451. Epub 2016 Jan 11.

Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146451PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709197PMC
July 2016

ChREBP Regulates Itself and Metabolic Genes Implicated in Lipid Accumulation in β-Cell Line.

PLoS One 2016 25;11(1):e0147411. Epub 2016 Jan 25.

Clinical Molecular Pathology Laboratory, Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147411PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725739PMC
July 2016

MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex.

Hum Mol Genet 2016 07 10;25(14):3029-3041. Epub 2016 Jun 10.

Genetics and Genome Biology Program, The Hospital for Sick Children, The Peter Gilgan Centre for Research and Learning, Toronto, ON M5G 0A4, Canada

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http://dx.doi.org/10.1093/hmg/ddw156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181597PMC
July 2016

ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity.

Sci Rep 2016 07 14;6:29669. Epub 2016 Jul 14.

Nephrology Division, Department of Medicine, Selzman Institute for Kidney Health, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1038/srep29669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944137PMC
July 2016

Acute Treatment of Resveratrol Alleviates Doxorubicin-Induced Myotoxicity in Aged Skeletal Muscle Through SIRT1-Dependent Mechanisms.

J Gerontol A Biol Sci Med Sci 2016 06 8;71(6):730-9. Epub 2015 Oct 8.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong 852, China.

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http://dx.doi.org/10.1093/gerona/glv175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888387PMC
June 2016

Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.

Endocr Rev 2016 06 1;37(3):190-222. Epub 2016 Apr 1.

Division of Endocrinology (Y.Y.), Department of Medicine, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio 44109; and Diabetes and Endocrinology Research Center (L.C.), Division of Diabetes, Endocrinology and Metabolism, Departments of Medicine, Molecular and Cellular Biology, Biochemistry and Molecular Biology, and Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030.

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http://dx.doi.org/10.1210/er.2015-1116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890265PMC
June 2016

Current and future molecular diagnostics in non-small-cell lung cancer.

Expert Rev Mol Diagn 2015 7;15(8):1061-74. Epub 2015 Jul 7.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, Hong Kong Polytechnic University, Hong Kong Special Administrative Region, Hong Kong, China.

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http://dx.doi.org/10.1586/14737159.2015.1063420DOI Listing
April 2016

Personalized Medicine: Cell and Gene Therapy Based on Patient-Specific iPSC-Derived Retinal Pigment Epithelium Cells.

Adv Exp Med Biol 2016 ;854:549-55

New York Presbyterian Hospital/Columbia University Medical Center, 10032, New York, NY, USA.

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http://dx.doi.org/10.1007/978-3-319-17121-0_73DOI Listing
April 2016

A community-based cross-sectional immunisation survey in parents of primary school students.

NPJ Prim Care Respir Med 2016 Apr 7;26:16011. Epub 2016 Apr 7.

Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1038/npjpcrm.2016.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823920PMC
April 2016

Coexpression Pattern Analysis of NPM1-Associated Genes in Chronic Myelogenous Leukemia.

Biomed Res Int 2015 15;2015:610595. Epub 2015 Apr 15.

Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

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http://dx.doi.org/10.1155/2015/610595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413041PMC
February 2016

Differential expression of inflammation-related genes in IL-4 transgenic mice before and after the onset of atopic dermatitis skin lesions.

Mol Cell Probes 2016 Feb 14;30(1):30-8. Epub 2015 Nov 14.

Department of Dermatology, University of Illinois, Chicago, IL, USA; Department of Microbiology/Immunology, University of Illinois, Chicago, IL, USA; Medical Service, Jesse Brown VA Med Center, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mcp.2015.11.001DOI Listing
February 2016

Ablation of a small subpopulation of diabetes-specific bone marrow-derived cells in mice protects against diabetic neuropathy.

Am J Physiol Endocrinol Metab 2016 Feb 22;310(4):E269-75. Epub 2015 Dec 22.

Division of Diabetes, Endocrinology, and Metabolism and the Diabetes Research Center, Departments of Medicine, Molecular and Cellular Biology, Biochemistry, and Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas; and

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http://ajpendo.physiology.org/content/ajpendo/early/2015/12/
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http://ajpendo.physiology.org/lookup/doi/10.1152/ajpendo.003
Publisher Site
http://dx.doi.org/10.1152/ajpendo.00381.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971812PMC
February 2016

Implications of MicroRNAs in the Treatment of Gefitinib-Resistant Non-Small Cell Lung Cancer.

Int J Mol Sci 2016 Feb 15;17(2):237. Epub 2016 Feb 15.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.3390/ijms17020237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783968PMC
February 2016

End-of-life decision-making for newborns: a 12-year experience in Hong Kong.

Arch Dis Child Fetal Neonatal Ed 2016 Jan 13;101(1):F37-42. Epub 2015 Aug 13.

Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1136/archdischild-2015-308659DOI Listing
January 2016

Gene network exploration of crosstalk between apoptosis and autophagy in chronic myelogenous leukemia.

Biomed Res Int 2015 3;2015:459840. Epub 2015 Mar 3.

Department of Health Technology and Informatics, Hong Kong Polytechnic University, Lee Shau Kee Building, Hung Hom, Kowloon, Hong Kong.

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http://dx.doi.org/10.1155/2015/459840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363532PMC
December 2015

Effects of long-term resveratrol-induced SIRT1 activation on insulin and apoptotic signalling in aged skeletal muscle.

Acta Diabetol 2015 Dec 12;52(6):1063-75. Epub 2015 May 12.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1007/s00592-015-0767-3DOI Listing
December 2015

Unacylated ghrelin restores insulin and autophagic signaling in skeletal muscle of diabetic mice.

Pflugers Arch 2015 Dec 31;467(12):2555-69. Epub 2015 Jul 31.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1007/s00424-015-1721-5DOI Listing
December 2015

The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice.

Endocrinology 2015 Dec 16;156(12):4474-91. Epub 2015 Sep 16.

Children's Nutrition Research Center (L.Z., P.X., X.C., Y.Y., A.O.H., Y.Xi., K.S., X.Y., F.Z., H.D., C.W., C.Y., M.F., Y.Xu), Department of Pediatrics; Diabetes Research Center (P.S., L.C.), Department of Medicine; and Department of Molecular and Cellular Biology (L.C., Y.Xu), Baylor College of Medicine, and Brown Foundation Institute of Molecular Medicine (Q.T.), University of Texas Health Science Center at Houston, Houston, Texas 77030; Department of Gastroenterology (L.Z.), Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, People's Republic of China; Medical College of Qingdao University (C.Y.), Qingdao 266020, People's Republic of China; Department of Cancer Biology (S.A.K.), Vontz Center for Molecular Studies, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267; Department of Pathology (J.Z.), Harvard Medical School, and Department of Cancer Biology Dana-Farber Cancer Institute, Boston, Massachusetts 02115; and Department of Biomedical Research (D.J.C.), Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048.

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http://dx.doi.org/10.1210/en.2015-1660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655219PMC
December 2015

FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance.

Endocrinology 2015 Nov 6;156(11):4020-32. Epub 2015 Aug 6.

Diabetes and Endocrinology Research Center (A.M.N.-A., N.P., M.L., L.C.), Department of Medicine, and Children's Nutrition Research Center (A.M.N.-A., M.M., S.G., F.Z.), Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030; and Charité University School of Medicine (M.S.), Institute of Pharmacology, Center for Cardiovascular Research, 10115 Berlin, Germany.

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http://dx.doi.org/10.1210/en.2015-1210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606753PMC
November 2015

SIRT1-dependent myoprotective effects of resveratrol on muscle injury induced by compression.

Front Physiol 2015 21;6:293. Epub 2015 Oct 21.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University Hong Kong, Hong Kong.

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http://dx.doi.org/10.3389/fphys.2015.00293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617057PMC
November 2015

Eruptive Syringocystadenoma Papilliferum, Keratoacanthoma, and Verruca Vulgaris in a Keratinocytic Epidermal Nevus on the Leg.

Skinmed 2015;13(5):395-7. Epub 2015 Oct 1.

Department of Dermatology, University of Illinois at Chicago College of Medicine, Chicago, IL.

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October 2015

Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.

Mol Endocrinol 2015 Sep 20;29(9):1320-33. Epub 2015 Jul 20.

Department of Molecular and Cellular Biology (S.M.H., D.A.B., K.V.A., M.Mo., M.P.H., W.L., B.Y., L.C., D.D.M., M.A.M., S.E.M.), Baylor College of Medicine, Houston, Texas 77030; Department of Biochemistry and Molecular Biology (W.L.), Wright State University Boonshoft School of Medicine, Dayton, Ohio 45435; Hans Popper Laboratory of Molecular Hepatology (M.Mu., M.T.), Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; Laboratory of Experimental Hepatology (M.W.), Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria; Diabetes and Endocrinology Research Center (L.C., M.B.), Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Baylor College of Medicine, and the Baylor St Luke's Medical Center, Houston, Texas 77030; and Division of Radiation Oncology (S.E.M.), The University of Texas MD Anderson Cancer Center, Houston, Texas 77030.

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http://dx.doi.org/10.1210/me.2015-1084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552434PMC
September 2015

Rapid resolution of retinoschisis with acetazolamide.

Doc Ophthalmol 2015 Aug 22;131(1):63-70. Epub 2015 Mar 22.

Barbara and Donald Jonas Laboratory of Stem Cell and Regenerative Medicine, Department of Ophthalmology, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1007/s10633-015-9496-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504776PMC
August 2015

Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice.

FASEB J 2015 Aug 7;29(8):3537-48. Epub 2015 May 7.

*Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA; Children's Nutrition Research Center, U.S. Department of Agriculture, Houston, Texas, USA; and Department of Stem Cell Biology and Regenerative Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan

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http://dx.doi.org/10.1096/fj.15-271452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511209PMC
August 2015

Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin.

Endocrinology 2015 Jun 9;156(6):1982-94. Epub 2015 Mar 9.

Department of Medicine (N.P., B.C., M.I., L.C.), Baylor College of Medicine, Houston, Texas 77030; Clinical Molecular Pathology Laboratory (N.P., K.M., C.S.-L.), Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand; Laboratory for Endocrinology, Metabolism and Kidney Diseases (M.I.) RIKEN Center for Integrative Medical Sciences, Yokohama, Japan 230-0045; Division of Biostatistics (J.C., W.L.), Dan L. Duncan Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030; and Molecular Medicine Program (K.M.), Multidisciplinary Unit, Faculty of Science, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1210/en.2014-1666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430618PMC
June 2015

Novel approach for coexpression analysis of E2F1-3 and MYC target genes in chronic myelogenous leukemia.

Biomed Res Int 2014 10;2014:439840. Epub 2014 Aug 10.

Department of Health Technology and Informatics, Hong Kong Polytechnic University, Lee Shau Kee Building, Hung Hom, Kowloon, Hong Kong.

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http://www.hindawi.com/journals/bmri/2014/439840/
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http://dx.doi.org/10.1155/2014/439840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142389PMC
May 2015

The effect of diabetes self-management education on body weight, glycemic control, and other metabolic markers in patients with type 2 diabetes mellitus.

J Diabetes Res 2014 17;2014:789761. Epub 2014 Jul 17.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

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http://dx.doi.org/10.1155/2014/789761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127232PMC
April 2015

Protective effects of desacyl ghrelin on diabetic cardiomyopathy.

Acta Diabetol 2015 Apr 6;52(2):293-306. Epub 2014 Sep 6.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1007/s00592-014-0637-4DOI Listing
April 2015

Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis.

J Physiol 2015 Apr 9;593(8):1887-99. Epub 2015 Feb 9.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1113/jphysiol.2014.270101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405749PMC
April 2015

PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.

Diabetes 2015 Feb 20;64(2):529-40. Epub 2014 Oct 20.

Division of Diabetes, Endocrinology and Metabolism, Diabetes and Endocrinology Research Center, and Department of Medicine, Baylor College of Medicine, Houston, TX Division of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX

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http://dx.doi.org/10.2337/db13-1737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303975PMC
February 2015

Bone marrow-derived TNF-α causes diabetic neuropathy in mice.

Diabetologia 2015 Feb 16;58(2):402-10. Epub 2014 Nov 16.

Department of Medicine, Baylor College of Medicine, One Baylor Plaza (MS: BCM185), Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s00125-014-3440-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289451PMC
February 2015

[D-Lys3]-GHRP-6 exhibits pro-autophagic effects on skeletal muscle.

Mol Cell Endocrinol 2015 Feb 29;401:155-64. Epub 2014 Oct 29.

Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.09.031DOI Listing
February 2015

Molecular mechanisms underlying fasting modulated liver insulin sensitivity and metabolism in male lipodystrophic Bscl2/Seipin-deficient mice.

Endocrinology 2014 Nov 5;155(11):4215-25. Epub 2014 Aug 5.

Department of Physiology (W.C., H.Z.), Medical College of Georgia at Georgia Regents University, Augusta, Georgia 30912; and Diabetes and Endocrinology Research Center, Division of Diabetes, Endocrinology and Metabolism, Departments of Medicine (P.S., L.L., L.C.), Molecular and Cellular Biology (L.C.), and Biochemistry, Baylor College of Medicine (L.C.), and St. Luke's Medical Center (L.C.), Houston, Texas 77030.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2014-1292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197977PMC
November 2014

MondoA deficiency enhances sprint performance in mice.

Biochem J 2014 Nov;464(1):35-48

‡Richard Roudebush VA Medical Center, 1481 West Tenth Street, Indianapolis, IN 46202, U.S.A.

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http://dx.doi.org/10.1042/BJ20140530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410994PMC
November 2014