Publications by authors named "Lawrence A Siegel"

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Two cases of zolpidem-associated homicide.

Prim Care Companion CNS Disord 2012 23;14(4). Epub 2012 Aug 23.

Department of Psychology, Marymount Manhattan College, New York, and Department of Psychiatry, The State University of New York, Downstate Medical Center, Brooklyn, USA.

Zolpidem is the most commonly prescribed medication for the short-term treatment of insomnia. Adverse reactions include nightmares, confusion, and memory deficits. Reported rare adverse neuropsychiatric reactions include sensory distortions such as hallucinations. Previous research has identified 4 factors that may place a patient at increased risk of zolpidem-associated psychotic or delirious reactions: (1) concomitant use of a selective serotonin reuptake inhibitor (SSRI), (2) female gender, (3) advanced age, and (4) zolpidem doses of 10 mg or higher. In this article, 2 cases are presented in which individuals killed their spouses and claimed total or partial amnesia. Neither individual had a history of aggressive behavior. Both had concomitantly taken 10 mg or more of zolpidem in addition to an SSRI (paroxetine).
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June 2013