Laurie J Goodyear

Laurie J Goodyear

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Laurie J Goodyear

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Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity.

Mol Metab 2019 Dec 10;30:203-220. Epub 2019 Oct 10.

Fraternal Order of Eagles Diabetes Research Center and Division of Endocrinology and Metabolism, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819874PMC
December 2019

Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting.

Biomed Pharmacother 2019 Sep 6;117:109197. Epub 2019 Jul 6.

Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2019.109197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686878PMC
September 2019

Sucrose nonfermenting AMPK-related kinase (SNARK) regulates exercise-stimulated and ischemia-stimulated glucose transport in the heart.

J Cell Biochem 2019 01 7;120(1):685-696. Epub 2018 Sep 7.

Integrative Physiology and Metabolism Section, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/jcb.27425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347018PMC
January 2019

Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue.

iScience 2019 Jan 3;11:425-439. Epub 2019 Jan 3.

Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 460 W. 12(th) Avenue, Columbus, OH 43210, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348298PMC
January 2019

Postexercise improvement in glucose uptake occurs concomitant with greater γ3-AMPK activation and AS160 phosphorylation in rat skeletal muscle.

Am J Physiol Endocrinol Metab 2018 11 21;315(5):E859-E871. Epub 2018 Aug 21.

Muscle Biology Laboratory, School of Kinesiology, University of Michigan , Ann Arbor, Michigan.

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http://dx.doi.org/10.1152/ajpendo.00020.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293165PMC
November 2018

Muscle-Adipose Tissue Cross Talk.

Cold Spring Harb Perspect Med 2018 08 1;8(8). Epub 2018 Aug 1.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215.

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http://dx.doi.org/10.1101/cshperspect.a029801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685935PMC
August 2018

Voluntary wheel running promotes resilience to chronic social defeat stress in mice: a role for nucleus accumbens ΔFosB.

Neuropsychopharmacology 2018 08 24;43(9):1934-1942. Epub 2018 May 24.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1038/s41386-018-0103-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046059PMC
August 2018

Tribbles 3 regulates protein turnover in mouse skeletal muscle.

Biochem Biophys Res Commun 2017 11 27;493(3):1236-1242. Epub 2017 Sep 27.

Division of Applied Physiology, Department of Exercise Science, University of South Carolina, Columbia, SC 29208, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.09.134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675010PMC
November 2017

Validity Assessment of 5 Day Repeated Forced-Swim Stress to Model Human Depression in Young-Adult C57BL/6J and BALB/cJ Mice.

eNeuro 2016 Nov-Dec;3(6). Epub 2016 Dec 29.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215; Department of Medicine, Brigham, and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215.

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http://dx.doi.org/10.1523/ENEURO.0201-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197406PMC
October 2017

Lipidomic Adaptations in White and Brown Adipose Tissue in Response to Exercise Demonstrate Molecular Species-Specific Remodeling.

Cell Rep 2017 02;18(6):1558-1572

Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558157PMC
February 2017

Exercise and Regulation of Carbohydrate Metabolism.

Prog Mol Biol Transl Sci 2015 20;135:17-37. Epub 2015 Aug 20.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA; Department of Medicine, Brigham, and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/bs.pmbts.2015.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727532PMC
November 2016

Exercise regulation of adipose tissue.

Adipocyte 2016 Apr-Jun;5(2):153-62. Epub 2016 May 18.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1080/21623945.2016.1191307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916870PMC
July 2016

Relationship of brown adipose tissue perfusion and function: a study through β2-adrenoreceptor stimulation.

J Appl Physiol (1985) 2016 Apr 28;120(8):825-32. Epub 2016 Jan 28.

Cardiac Ultrasound Laboratory and Cardiovascular Research Center, Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.1152/japplphysiol.00634.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835910PMC
April 2016

Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling.

Biochem Biophys Res Commun 2016 Feb 20;470(4):783-91. Epub 2016 Jan 20.

Division of Applied Physiology, Department of Exercise Science, University of South Carolina, Columbia, SC 29208, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.01.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768059PMC
February 2016

MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network.

EMBO Rep 2015 Oct 24;16(10):1378-93. Epub 2015 Aug 24.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA

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http://dx.doi.org/10.15252/embr.201540837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766451PMC
October 2015

Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.

Nat Commun 2015 Aug 24;6:8054. Epub 2015 Aug 24.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, 1 Joslin Plaza, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/ncomms9054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552045PMC
August 2015

Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations.

Diabetes 2015 Jul 7;64(7):2361-8. Epub 2015 Jun 7.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.2337/db15-0227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477356PMC
July 2015

Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes.

Nat Med 2015 Jul 15;21(7):760-8. Epub 2015 Jun 15.

1] Section on Integrative Physiology and Metabolism, Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA. [2] Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nm.3881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496292PMC
July 2015

A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis.

Diabetes 2015 Jun 20;64(6):2002-14. Epub 2015 Jan 20.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db14
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http://dx.doi.org/10.2337/db14-0704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439563PMC
June 2015

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.

Cell Rep 2015 May 14;11(8):1220-35. Epub 2015 May 14.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.04.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449334PMC
May 2015

Exercise before and during pregnancy prevents the deleterious effects of maternal high-fat feeding on metabolic health of male offspring.

Diabetes 2015 Feb 9;64(2):427-33. Epub 2014 Sep 9.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db13
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http://dx.doi.org/10.2337/db13-1848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303966PMC
February 2015

Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle.

Adv Physiol Educ 2014 Dec;38(4):308-14

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1152/advan.00080.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315445PMC
December 2014

Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice.

Am J Physiol Regul Integr Comp Physiol 2014 Jun 16;306(12):R925-33. Epub 2014 Apr 16.

Research Division, Joslin Diabetes Center, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and

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http://ajpregu.physiology.org/content/ajpregu/306/12/R925.fu
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http://ajpregu.physiology.org/content/ajpregu/early/2014/04/
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http://ajpregu.physiology.org/cgi/doi/10.1152/ajpregu.00027.
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http://dx.doi.org/10.1152/ajpregu.00027.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159733PMC
June 2014

Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle.

J Physiol 2014 Jan 18;592(2):351-75. Epub 2013 Nov 18.

The August Krogh Centre, Department of Nutrition, Exercise and Sports, Section of Molecular Physiology, University of Copenhagen, Universitetsparken 13 DK-2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1113/jphysiol.2013.266338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922499PMC
January 2014

Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation.

Exp Gerontol 2013 Nov 3;48(11):1274-84. Epub 2013 Aug 3.

Centre of Inflammation and Metabolism, August Krogh Centre, August Krogh Building, Department of Biology, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2013.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045249PMC
November 2013

The therapeutic potential of brown adipose tissue.

Hepatobiliary Surg Nutr 2013 Oct;2(5):286-7

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.3978/j.issn.2304-3881.2013.09.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924699PMC
October 2013

Contraction and AICAR stimulate IL-6 vesicle depletion from skeletal muscle fibers in vivo.

Diabetes 2013 Sep 12;62(9):3081-92. Epub 2013 Jun 12.

Research Division, Joslin Diabetes Center and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db12-1261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749330PMC
September 2013

Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake.

Antioxid Redox Signal 2013 Jul 9;19(3):243-57. Epub 2012 Oct 9.

Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1089/ars.2012.4536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691916PMC
July 2013

Characterization of an acute muscle contraction model using cultured C2C12 myotubes.

PLoS One 2012 31;7(12):e52592. Epub 2012 Dec 31.

Department of Health Promotion Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052592PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534077PMC
June 2013

Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle.

Cell Rep 2013 May 23;3(5):1449-56. Epub 2013 May 23.

Cardiovascular Institute, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688451PMC
May 2013

Exercise training-induced adaptations associated with increases in skeletal muscle glycogen content.

FEBS J 2013 Feb 7;280(3):916-26. Epub 2013 Jan 7.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1111/febs.12085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558638PMC
February 2013

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

J Clin Invest 2013 Jan 10;123(1):215-23. Epub 2012 Dec 10.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI62308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533266PMC
January 2013

Exercise increases TBC1D1 phosphorylation in human skeletal muscle.

Am J Physiol Endocrinol Metab 2011 Jul 19;301(1):E164-71. Epub 2011 Apr 19.

Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1152/ajpendo.00042.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129834PMC
July 2011

Myo1c regulates glucose uptake in mouse skeletal muscle.

J Biol Chem 2011 Feb 2;286(6):4133-40. Epub 2010 Dec 2.

Section on Integrative Physiology and Metabolism, the Joslin Diabetes Center, Boston, Massachusetts 02215, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.174938
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http://dx.doi.org/10.1074/jbc.M110.174938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039380PMC
February 2011

Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.

Biochem J 2010 Oct;431(2):311-20

Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, U.S.A.

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http://dx.doi.org/10.1042/BJ20101100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947193PMC
October 2010

Kinetics of contraction-induced GLUT4 translocation in skeletal muscle fibers from living mice.

Diabetes 2010 Sep 9;59(9):2134-44. Epub 2010 Jul 9.

Research Division, Joslin Diabetes Center and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db10-0233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927934PMC
September 2010

CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle.

Am J Physiol Endocrinol Metab 2010 Jun 9;298(6):E1150-60. Epub 2010 Mar 9.

Joslin Diabetes Center, Research Division, Department of Medicine, Brigham and Women'sHospital, and Harvard Medical School, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1152/ajpendo.00659.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886528PMC
June 2010

TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.

Diabetes 2010 Jun 18;59(6):1358-65. Epub 2010 Mar 18.

Research Division, Joslin Diabetes Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db09-1266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874696PMC
June 2010

Diabetes: Exercise and type 2 diabetes mellitus--good for body and mind?

Nat Rev Endocrinol 2010 Jun;6(6):303-4

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http://dx.doi.org/10.1038/nrendo.2010.47DOI Listing
June 2010

Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats.

Am J Physiol Endocrinol Metab 2009 Aug 2;297(2):E495-504. Epub 2009 Jun 2.

Research Division, Department of Medicine, and Harvard Medical School, Joslin Diabetes Center, Boston, Massachusetts 02215, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.90424.2008
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http://dx.doi.org/10.1152/ajpendo.90424.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724117PMC
August 2009

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle.

Aging (Albany NY) 2009 Aug 15;1(9):771-83. Epub 2009 Aug 15.

USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815736PMC
http://dx.doi.org/10.18632/aging.100075DOI Listing
August 2009

Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus.

Biochem Biophys Res Commun 2009 May 3;382(4):646-50. Epub 2009 Mar 3.

Obesity and Metabolism, JM-USDA HNRCA at Tufts University, Boston, MA 02111, USA.

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http://dx.doi.org/10.1016/j.bbrc.2009.02.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692044PMC
May 2009

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.

Diabetes 2008 Nov 26;57(11):2958-66. Epub 2008 Aug 26.

Department of Medicine, Research Division, Joslin Diabetes Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db07-1187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570392PMC
November 2008

The exercise pill--too good to be true?

N Engl J Med 2008 Oct;359(17):1842-4

Joslin Diabetes Center and Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcibr0806723DOI Listing
October 2008

Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles.

Cell 2008 Jul;134(1):37-47

Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cell.2008.05.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665268PMC
July 2008

Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway.

Am J Physiol Endocrinol Metab 2008 May 26;294(5):E889-97. Epub 2008 Feb 26.

Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.

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http://dx.doi.org/10.1152/ajpendo.00150.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882683PMC
May 2008

LKB1 and AMPK and the regulation of skeletal muscle metabolism.

Curr Opin Clin Nutr Metab Care 2008 May;11(3):227-32

Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MCO.0b013e3282fb7b76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887290PMC
May 2008

Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

J Biol Chem 2008 Apr 13;283(15):9787-96. Epub 2008 Feb 13.

The Joslin Diabetes Center Section on Metabolism and Proteomics Core and Harvard Medical School, One Joslin Place, Boston, MA 02215, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M708839200
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http://dx.doi.org/10.1074/jbc.M708839200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442306PMC
April 2008

Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise.

IUBMB Life 2008 Mar;60(3):145-53

Research Division, Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/iub.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885767PMC
March 2008

Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle.

Diabetes 2007 Dec 23;56(12):2854-62. Epub 2007 Aug 23.

Department of Metabolism, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db07-06
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http://dx.doi.org/10.2337/db07-0681DOI Listing
December 2007

Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes.

Curr Diab Rep 2007 Dec;7(6):399-401

The Joslin Diabetes Center and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1007/s11892-007-0065-8DOI Listing
December 2007

Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-.

Diabetes Res Clin Pract 2007 Sep 23;77 Suppl 1:S92-8. Epub 2007 Apr 23.

Research Division, Joslin Diabetes Center, and the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, One Joslin Place, Boston, MA 02215, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016882270700171
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http://dx.doi.org/10.1016/j.diabres.2007.01.040DOI Listing
September 2007

Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.

Diabetes 2007 Aug 18;56(8):2062-9. Epub 2007 May 18.

Research Division, Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.2337/db07-0255DOI Listing
August 2007

Exercise, MAPK, and NF-kappaB signaling in skeletal muscle.

J Appl Physiol (1985) 2007 Jul 15;103(1):388-95. Epub 2007 Feb 15.

Metabolism, Research Division, Joslin Diabetes Center, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.

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http://www.physiology.org/doi/10.1152/japplphysiol.00085.200
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July 2007

Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes.

Biochem J 2007 May;403(3):473-81

Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1042/BJ20061479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876380PMC
May 2007

Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation.

Diabetes 2007 May 7;56(5):1403-9. Epub 2007 Feb 7.

Research Division, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.2337/db06-1230DOI Listing
May 2007

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.

J Clin Invest 2007 May 12;117(5):1432-9. Epub 2007 Apr 12.

NMR Laboratory for Physiological Chemistry, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.

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http://www.jci.org/cgi/doi/10.1172/JCI30658
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847536PMC
May 2007

Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation.

Am J Physiol Endocrinol Metab 2007 Mar 14;292(3):E802-11. Epub 2006 Nov 14.

Department of Medicine, Dartmouth Medical School, Dartmouth College, Hanover, NH 03755-3833, USA.

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http://dx.doi.org/10.1152/ajpendo.00369.2006DOI Listing
March 2007

Role of Akt2 in contraction-stimulated cell signaling and glucose uptake in skeletal muscle.

Am J Physiol Endocrinol Metab 2006 Nov 27;291(5):E1031-7. Epub 2006 Jun 27.

The Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1152/ajpendo.00204.2006DOI Listing
November 2006

AMP-activated protein kinase and the regulation of glucose transport.

Am J Physiol Endocrinol Metab 2006 Nov 5;291(5):E867-77. Epub 2006 Jul 5.

Research Division, Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.00207.2006
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November 2006

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

J Biol Chem 2006 Oct 25;281(42):31478-85. Epub 2006 Aug 25.

Joslin Diabetes Center Research Division, Metabolism Section, Massachusetts 02215, USA.

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http://dx.doi.org/10.1074/jbc.M605461200DOI Listing
October 2006

Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise.

Metabolism 2006 Aug;55(8):1046-52

Center for Physical Activity and Nutrition (C-PAN), School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria 3125, Australia.

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http://dx.doi.org/10.1016/j.metabol.2006.03.016DOI Listing
August 2006

Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia.

Cell Metab 2006 May;3(5):355-66

Department of Systems Biology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cmet.2006.04.003DOI Listing
May 2006