Publications by authors named "Laurie Gay"

60Publications

Unique Genomic Landscape of High-Grade Neuroendocrine Cervical Carcinoma: Implications for Rethinking Current Treatment Paradigms.

JCO Precis Oncol 2020 3;4. Epub 2020 Sep 3.

Center for Personalized Cancer Therapy, University of California San Diego, La Jolla, CA.

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http://dx.doi.org/10.1200/PO.19.00248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529537PMC
September 2020

Analysis of Amplification: Next-Generation Sequencing of Patients With Diverse Malignancies.

JCO Precis Oncol 2018 13;2018. Epub 2018 Jul 13.

University of California, San Diego, Moores Cancer Center, La Jolla.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106866PMC
http://dx.doi.org/10.1200/PO.17.00235DOI Listing
July 2018

Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.

Structure 2018 07 31;26(7):972-986.e6. Epub 2018 May 31.

Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09692126183016
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http://dx.doi.org/10.1016/j.str.2018.04.018DOI Listing
July 2018

Mutations and PD-1 Inhibitor Resistance in -Mutant Lung Adenocarcinoma.

Cancer Discov 2018 07 17;8(7):822-835. Epub 2018 May 17.

Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-18-0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030433PMC
July 2018

in Lung Cancers: Analysis of Patient Cases Reveals Recurrent Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

JCO Precis Oncol 2018 19;2. Epub 2018 Apr 19.

, Vancouver General Hospital, Vancouver, British Columbia, Canada; , , , , , , , , , , , , , , , , , , and , Foundation Medicine, Cambridge, MA; , The Angeles Clinic and Research Institute and Cedars-Sinai Medical Center, Los Angeles; , University of California San Diego, San Diego; , University of California, San Francisco, San Francisco; and , University of California, Irvine, Medical Center, Irvine, CA; , Cleveland Clinic; and , University Hospitals Cleveland Medical Center and Case Western Reserve University, Cleveland, OH; , Soroka Medical Center and Ben-Gurion University, Beer-Sheve, Israel; , Northwestern University Feinberg School of Medicine Northwestern Medical Center, Chicago, IL; and , Cancer Institute of New Jersey, New Brunswick, NJ.

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http://dx.doi.org/10.1200/PO.17.00172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446447PMC
April 2018

Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers.

Clin Cancer Res 2018 07 3;24(13):3059-3068. Epub 2018 Apr 3.

Department of Pharmaceutical Sciences, Skaags School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030480PMC
July 2018

Elevated tumor mutational burden and prolonged clinical response to anti-PD-L1 antibody in platinum-resistant recurrent ovarian cancer.

Gynecol Oncol Rep 2017 Aug 27;21:78-80. Epub 2017 Jun 27.

Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, United States.

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http://dx.doi.org/10.1016/j.gore.2017.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510487PMC
August 2017

reversion mutation acquired after treatment identified by liquid biopsy.

Gynecol Oncol Rep 2017 Aug 21;21:57-60. Epub 2017 Jun 21.

Foundation Medicine, Inc., Cambridge, MA, USA.

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http://dx.doi.org/10.1016/j.gore.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496455PMC
August 2017

The sleeping ugly: Tumour microenvironment's act to make or break the spell of dormancy.

Biochim Biophys Acta Rev Cancer 2017 Aug 10;1868(1):231-238. Epub 2017 May 10.

Tumour Host Interaction Laboratory, The Francis Crick Institute, 1 Midland Rd, NW1 1AT London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2017.05.002DOI Listing
August 2017

Structure and function of a broad-specificity chitin deacetylase from Aspergillus nidulans FGSC A4.

Sci Rep 2017 05 11;7(1):1746. Epub 2017 May 11.

Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences, Ås, 1432, Norway.

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http://dx.doi.org/10.1038/s41598-017-02043-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431758PMC
May 2017

Comprehensive genomic profiling (CGP) of ovarian clear cell carcinomas (OCCC) identifies clinically relevant genomic alterations (CRGA) and targeted therapy options.

Gynecol Oncol Rep 2017 May 1;20:62-66. Epub 2017 Mar 1.

Cancer Treatment Centers of America at Eastern Regional Medical Center, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.gore.2017.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357688PMC
May 2017

Next-Generation Sequencing Reveals Pathway Activations and New Routes to Targeted Therapies in Cutaneous Metastatic Melanoma.

Am J Dermatopathol 2017 Jan;39(1):1-13

*Professor of Pathology and Dermatology, Albany Medical College, Albany, NY; †Pathology Resident, Unversidade Estadual Paulista, Botucatu, Brazil; ‡Pathology Resident, Albany Medical College, Albany, NY; §Director of Research, Associate Professor, Department of Pathology, Albany, Medical College, Albany, NY; ¶Research and Development, Foundation Medicine, Inc, Cambridge, MA; ‖Chief Medical Officer, Foundation Medicine, Inc, Cambridge, MA; #Chief Scientific Officer, Foundation Medicine, Inc, Cambridge, MA; **Associate Medical Officer, Foundation Medicine, Inc, Cambridge, MA; ††Associate Medical Director, Foundation Medicine, Inc, Cambridge, MA; ‡‡Research Scientist, Foundation Medicine, Inc, Cambridge, MA; §§Chief, Professor of Pathology, Albany, Medical College, Albany, NY; and ¶¶Medical Director, Foundation Medicine, Inc, Cambridge, MA.

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http://dx.doi.org/10.1097/DAD.0000000000000729DOI Listing
January 2017

Comprehensive genomic sequencing and the molecular profiles of clinically advanced breast cancer.

Pathology 2017 Feb 26;49(2):120-132. Epub 2016 Dec 26.

Foundation Medicine, Inc., Cambridge, MA, United States.

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http://dx.doi.org/10.1016/j.pathol.2016.11.005DOI Listing
February 2017

Comprehensive Genomic Profiling of Central Giant Cell Lesions Identifies Clinically Relevant Genomic Alterations.

J Oral Maxillofac Surg 2017 May 1;75(5):955-961. Epub 2016 Nov 1.

Chair and Consultant, Division of Oral and Maxillofacial Surgery, Department of Surgery, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.joms.2016.10.027DOI Listing
May 2017

Host endothelial S1PR1 regulation of vascular permeability modulates tumor growth.

Am J Physiol Cell Physiol 2014 Jul 16;307(1):C14-24. Epub 2014 Apr 16.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California; and Department of Immunology, The Scripps Research Institute, La Jolla, California

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http://dx.doi.org/10.1152/ajpcell.00043.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080184PMC
July 2014

New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.

Oncologist 2014 Mar 21;19(3):235-42. Epub 2014 Feb 21.

Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, New York, USA; Foundation Medicine, Inc., Cambridge, Massachusetts, USA; University of Chicago, Chicago, Illinois, USA; The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1634/theoncologist.2013-0352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958461PMC
March 2014

Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.

J Clin Invest 2013 Mar 15;123(3):1068-81. Epub 2013 Feb 15.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1172/JCI64264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582128PMC
March 2013

Platelets alter tumor cell attributes to propel metastasis: programming in transit.

Cancer Cell 2011 Nov;20(5):553-4

The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561081100407
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http://dx.doi.org/10.1016/j.ccr.2011.11.001DOI Listing
November 2011

Contribution of platelets to tumour metastasis.

Nat Rev Cancer 2011 Feb;11(2):123-34

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://www.nature.com/articles/nrc3004
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http://dx.doi.org/10.1038/nrc3004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894505PMC
February 2011

Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network.

Proc Natl Acad Sci U S A 2008 Feb 1;105(6):1931-6. Epub 2008 Feb 1.

Department of Pathology and Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1073/pnas.0706545105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542865PMC
February 2008

A conserved dimer and global conformational changes in the structure of apo-PknE Ser/Thr protein kinase from Mycobacterium tuberculosis.

J Mol Biol 2006 Jul 19;360(2):409-20. Epub 2006 May 19.

Department of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720-3206, USA.

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http://dx.doi.org/10.1016/j.jmb.2006.05.015DOI Listing
July 2006

Structure/function studies of Ser/Thr and Tyr protein phosphorylation in Mycobacterium tuberculosis.

J Mol Microbiol Biotechnol 2005 ;9(3-4):167-81

Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3206, USA.

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http://dx.doi.org/10.1159/000089645DOI Listing
March 2006

Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains.

Protein Sci 2005 Jul;14(7):1918-21

Department of Molecular and Cell Biology, University of California, Berkeley, 94720, USA.

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http://doi.wiley.com/10.1110/ps.051413405
Publisher Site
http://dx.doi.org/10.1110/ps.051413405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253351PMC
July 2005