Publications by authors named "Laurie B Griffin"

15Publications

Predicting the pathogenicity of aminoacyl-tRNA synthetase mutations.

Methods 2017 01 20;113:139-151. Epub 2016 Nov 20.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, United States; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253330PMC
January 2017

Dimerization is required for GARS-mediated neurotoxicity in dominant CMT disease.

Hum Mol Genet 2016 Apr 7;25(8):1528-42. Epub 2016 Feb 7.

Developmental Biology, Biomedical Research Foundation Academy of Athens, Soranou Ephessiou 4, 11527 Athens, Greece,

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http://dx.doi.org/10.1093/hmg/ddw031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805310PMC
April 2016

A novel AARS mutation in a family with dominant myeloneuropathy.

Neurology 2015 May 22;84(20):2040-7. Epub 2015 Apr 22.

From the Department of Neurology (W.W.M., S.S.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Cellular and Molecular Biology Program (L.B.G., A.A.), Medical Science Training Program (L.B.G.), and the Departments of Human Genetics (A.A.) and Neurology (A.A.), University of Michigan Medical School, Ann Arbor; the Neurogenetics Group (I.M., J.B., P.D.J.) and the Molecular Neurogenomics Group (E.D.V., A.J.), VIB, Department of Molecular Genetics, University of Antwerp; the Neurogenetics Laboratory (I.M., J.B., E.D.V., P.D.J., A.J.), Institute Born-Bunge, University of Antwerp; and the Department of Neurology (J.B., P.D.J.), Antwerp University Hospital, Belgium.

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http://dx.doi.org/10.1212/WNL.0000000000001583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442103PMC
May 2015

Loss-of-function alanyl-tRNA synthetase mutations cause an autosomal-recessive early-onset epileptic encephalopathy with persistent myelination defect.

Am J Hum Genet 2015 Apr 26;96(4):675-81. Epub 2015 Mar 26.

Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Center for Genetic Medicine Research, Children's National Health System, Washington, DC 20010, USA; Departments of Integrated Systems Biology and of Pediatrics, George Washington University, Washington, DC 20052, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385183PMC
April 2015

Impaired function is a common feature of neuropathy-associated glycyl-tRNA synthetase mutations.

Hum Mutat 2014 Nov;35(11):1363-71

Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, Michigan; Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1002/humu.22681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213347PMC
November 2014

Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.

J Natl Cancer Inst 2011 Jun 8;103(12):962-78. Epub 2011 Jun 8.

Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr-MSC 1104, 10 CRC 1W-3816, Bethesda, MD 20892-1104, USA.

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http://dx.doi.org/10.1093/jnci/djr156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119649PMC
June 2011

Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells.

Neoplasia 2011 Feb;13(2):145-53

Molecular Oncology Section, Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1928, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033593PMC
http://dx.doi.org/10.1593/neo.101202DOI Listing
February 2011