Publications Authored by Laurent Essioux

Combining expression of GPC3 in tumors and CD16 on NK cells from peripheral blood to identify patients responding to codrituzumab.

Authors:

Gong Chen Ya-Chi Chen Bernhard Reis Anton Belousov Lori Jukofsky Christine Rossin Axel Muehlig Chao Xu Laurent Essioux Toshihiko Ohtomo Laura Di Laurenzio Oscar Puig Ray Lee

Oncotarget 2018 Feb 2;9(12):10436-10444. Epub 2018 Jan 2.

Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.

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http://dx.doi.org/10.18632/oncotarget.23830	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828203	PMC

February 2018

Growth Differentiation Factor-15 and Risk of CKD Progression.

J Am Soc Nephrol 2017 Jul 3;28(7):2233-2240. Epub 2017 Feb 3.

Kidney Research Institute, Division of Nephrology, University of Washington, Seattle, Washington;

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http://dx.doi.org/10.1681/ASN.2016080919	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491285	PMC

July 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:

Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772	PMC

January 2017

Drug Target Identification and Validation: Global Pharmaceutical Industry Experts on Challenges, Best Strategies, Innovative Precompetitive Collaboration Concepts, and Future Areas of Industry Precompetitive Research and Development.

Authors:

Tobias Bergauer Thorsten Ruppert Laurent Essioux Olivia Spleiss

Ther Innov Regul Sci 2016 Nov 10;50(6):769-776. Epub 2016 Jul 10.

1 Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.

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http://journals.sagepub.com/doi/10.1177/2168479016651298	Publisher Site
http://dx.doi.org/10.1177/2168479016651298	DOI Listing

November 2016

Combined Plasma and Cerebrospinal Fluid Signature for the Prediction of Midterm Progression From Mild Cognitive Impairment to Alzheimer Disease.

Authors:

Benoit Lehallier Laurent Essioux Javier Gayan Roxana Alexandridis Tania Nikolcheva Tony Wyss-Coray Markus Britschgi

JAMA Neurol 2016 02 14;73(2):203-212. Epub 2015 Dec 14.

Neuroscience, Ophthalmology, and Rare Diseases Discovery and Translational Areas, Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd, Basel, Switzerland.

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http://dx.doi.org/10.1001/jamaneurol.2015.3135	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214993	PMC

February 2016

Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker.

Sci Transl Med 2015 Dec;7(316):316ra193

Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac7071	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861144	PMC

December 2015

MDM2 antagonist clinical response association with a gene expression signature in acute myeloid leukaemia.

Authors:

Hua Zhong Gong Chen Lori Jukofsky David Geho Sung Won Han Fabian Birzele Sabine Bader Lucia Himmelein James Cai Zayed Albertyn Mark Rothe Laurent Essioux Helmut Burtscher Steven A Middleton Ruediger Rueger Lin-Chi Chen Markus Dangl Gwen Nichols William E Pierceall

Br J Haematol 2015 Nov 8;171(3):432-5. Epub 2015 Apr 8.

Translational Medicine Oncology, Roche Pharmaceutical Research and Early Development, Roche Innovation Center New York, New York, NY, USA.

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http://dx.doi.org/10.1111/bjh.13411	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104337	PMC

November 2015

Multiple protein analysis of formalin-fixed and paraffin-embedded tissue samples with reverse phase protein arrays.

Authors:

Maziar Assadi Jens Lamerz Tiantom Jarutat Alexandra Farfsing Hubert Paul Berthold Gierke Ewa Breitinger Markus F Templin Laurent Essioux Susanne Arbogast Miro Venturi Michael Pawlak Hanno Langen Thomas Schindler

Mol Cell Proteomics 2013 Sep 7;12(9):2615-22. Epub 2013 May 7.

Translational Research Sciences, Pharma Research & Early Development, F. Hoffmann - La Roche AG, Basel, Switzerland.

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http://dx.doi.org/10.1074/mcp.M112.023051	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769334	PMC

September 2013

The frequency of anti-infliximab antibodies in patients with rheumatoid arthritis treated in routine care and the associations with adverse drug reactions and treatment failure.

Authors:

Sophine B Krintel Veit Peter Grunert Merete L Hetland Julia S Johansen Matthias Rothfuss Giuseppe Palermo Laurent Essioux Ursula Klause

Rheumatology (Oxford) 2013 Jul 4;52(7):1245-53. Epub 2013 Mar 4.

Department of Medicine, Copenhagen University Hospital Herlev, Herlev Ringvej 75, DK-2730 Herlev, Denmark.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.	Publisher Site
http://dx.doi.org/10.1093/rheumatology/ket017	DOI Listing

July 2013

Quantitative chemical proteomics profiling differentiates erlotinib from gefitinib in EGFR wild-type non-small cell lung carcinoma cell lines.

Authors:

Angélique Augustin Jens Lamerz Hélène Meistermann Sabrina Golling Stefan Scheiblich Johannes C Hermann Guillemette Duchateau-Nguyen Manuel Tzouros David W Avila Hanno Langen Laurent Essioux Barbara Klughammer

Mol Cancer Ther 2013 Apr 31;12(4):520-9. Epub 2013 Jan 31.

Translational Research Sciences, Pharmaceuticals Division, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0880	DOI Listing

April 2013

Improving basic and translational science by accounting for litter-to-litter variation in animal models.

Authors:

Stanley E Lazic Laurent Essioux

BMC Neurosci 2013 Mar 22;14:37. Epub 2013 Mar 22.

In Silico Lead Discovery, Novartis Institutes for Biomedical Research, Switzerland.

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http://dx.doi.org/10.1186/1471-2202-14-37	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661356	PMC

March 2013

ViralZone: recent updates to the virus knowledge resource.

Authors:

Patrick Masson Chantal Hulo Edouard De Castro Hans Bitter Lore Gruenbaum Laurent Essioux Lydie Bougueleret Ioannis Xenarios Philippe Le Mercier

Nucleic Acids Res 2013 Jan 28;41(Database issue):D579-83. Epub 2012 Nov 28.

SIB Swiss Institute of Bioinformatics, Swiss-Prot Group, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1093/nar/gks1220	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531065	PMC

January 2013

CD6 and syntaxin binding protein 6 variants and response to tumor necrosis factor alpha inhibitors in Danish patients with rheumatoid arthritis.

Authors:

Sophine B Krintel Laurent Essioux Assaf Wool Julia S Johansen Ehud Schreiber Tomer Zekharya Pinchas Akiva Mikkel Ostergaard Merete L Hetland

PLoS One 2012 7;7(6):e38539. Epub 2012 Jun 7.

DANBIO Registry and Department of Rheumatology, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038539	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369852	PMC

December 2012

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.

Authors:

Sophine B Krintel Giuseppe Palermo Julia S Johansen Søren Germer Laurent Essioux Ryma Benayed Laura Badi Mikkel Ostergaard Merete L Hetland

Pharmacogenet Genomics 2012 Aug;22(8):577-89

DANBIO Registry and Department of Rheumatology, Hvidovre and Glostrup Hospitals, Glostrup, Denmark.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land	Publisher Site
http://dx.doi.org/10.1097/FPC.0b013e3283544043	DOI Listing

August 2012

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact.

Nat Rev Drug Discov 2010 06;9(6):435-45

Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US FDA, Building 51, 10903 New Hampshire Avenue, Silver Spring, Maryland 20903-002, USA.

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