Publications by authors named "Laurent Dubuquoy"

68Publications

INTEGRATED MULTI-OMICS REVEALS GLUCOSE USE REPROGRAMMING AND IDENTIFIES A NOVEL HEXOKINASE IN ALCOHOLIC HEPATITIS.

Gastroenterology 2020 Dec 9. Epub 2020 Dec 9.

Division of Gastroenterology and Hepatology, Departments of Medicine and Nutrition, and Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, NC; Department of Gastroenterology and Hepatology, Division of Medicine, University of Pittsburgh Medical Center (UPMC). Pittsburgh, PA. Electronic address:

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December 2020

High carriage of adherent invasive in wildlife and healthy individuals.

Gut Pathog 2018 14;10:23. Epub 2018 Jun 14.

Lille Inflammation Research International Center, UMR 995 Inserm, Lille University, CHRU Lille, Lille, France.

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June 2018

β-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway.

J Hepatol 2018 09 27;69(3):687-696. Epub 2018 Apr 27.

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520, USA; USA West Haven Veterans Medical Center, West Haven, CT 06516, USA. Electronic address:

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September 2018

Cross regulation between mTOR signaling and O-GlcNAcylation.

J Bioenerg Biomembr 2018 06 9;50(3):213-222. Epub 2018 Mar 9.

CNRS, UMR 8576 - UGSF - Unité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, F 59000, Lille, France.

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June 2018

One- or Two-Step Synthesis of C-8 and N-9 Substituted Purines.

J Org Chem 2018 01 14;83(1):422-430. Epub 2017 Dec 14.

Univ. Lille, Inserm, ICPAL, U995 - LIRIC - Lille Inflammation Research International Center , 3 rue du Pr Laguesse BP83, F-59006 Lille, France.

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January 2018

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis.

Gastroenterology 2018 03 11;154(4):1009-1023.e14. Epub 2017 Nov 11.

INSERM, U1193, Paul-Brousse University Hospital, Hepatobiliary Centre, Villejuif, France; University Paris-Sud, Université Paris-Saclay, Faculté de Médecine Le Kremlin-Bicêtre, France; Assistance Publique-Hôpitaux de Paris (AP-HP), Pôle de Biologie Médicale, Paul-Brousse University Hospital, Villejuif, France. Electronic address:

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March 2018

Chronic bowel inflammation and inflammatory joint disease: Pathophysiology.

Joint Bone Spine 2017 Jul 3;84(4):417-420. Epub 2017 Jan 3.

Lille Inflammation Research International Center (LIRIC), U995, University Lille, Inserm, CHU Lille, 59000 Lille, France. Electronic address:

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July 2017

[Enteric microflora in inflammatory bowel disease patients].

Med Sci (Paris) 2016 Nov 23;32(11):968-973. Epub 2016 Dec 23.

LIRIC UMR 995 Inserm ; université de Lille ; CHRU de Lille, faculté de médecine, Place de Verdun, F-59045, Lille Cedex, France.

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November 2016

Short fungal fractions of β-1,3 glucans affect platelet activation.

Am J Physiol Heart Circ Physiol 2016 09 10;311(3):H725-34. Epub 2016 Jun 10.

Univ Lille Nord de France, Lille, France; UDSL, Lille, France; INSERM U995, Lille, France; CHRU Lille, Lille, France;

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September 2016

MicroRNA in alcoholic hepatitis: implications for pathophysiology and treatment.

Gut 2016 09 1;65(9):1400-1. Epub 2016 Jun 1.

LIRIC-Lille Inflammation Research International Center-U995, Univ. Lille, Inserm, CHU Lille, Lille, France.

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September 2016

Lipocalin 2 highlights the complex role of neutrophils in alcoholic liver disease.

Authors:
Laurent Dubuquoy

J Hepatol 2016 Apr 23;64(4):770-2. Epub 2016 Jan 23.

LIRIC - Lille Inflammation Research International Center, U995, Univ. Lille, Inserm, CHU Lille, F-59000 Lille, France. Electronic address:

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April 2016

Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis.

Inflamm Bowel Dis 2016 Feb;22(2):279-92

*Inserm, LIRIC UMR995, Lille, France; †CHRU de Lille, Service des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Claude Huriez, LIRIC, UMR995, Lille, France; ‡Department of Life, Health and Environmental Sciences, Gastroenterology Unit, University of L'Aquila, L'Aquila, Italy; §IBD, Lille, France; ‖Department of Pathobiology, Lerner Research Institute, and Department of Gastroenterology, Hepatology & Nutrition, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, Ohio; ¶Université Lille Nord de France, Lille, France; and **Department of Human Anatomy, University of Roma "La Sapienza," Roma, Italy.

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February 2016

Escherichia coli LF82 differentially regulates ROS production and mucin expression in intestinal epithelial T84 cells: implication of NOX1.

Inflamm Bowel Dis 2015 May;21(5):1018-26

*Inserm U1149, CNRS-ERL8252, Centre de Recherche sur l'Inflammation, Paris, France; †Université Paris Diderot, Sorbonne Paris Cité, Laboratoire d'Excellence Inflamex, Faculté de Médecine, Site Xavier Bichat, Paris, France; ‡Inserm U995-Team 1, Faculté de Médecine, Pôle recherche, Laboratoire J&K, Lille, France; §UMR 1071 Inserm/UdA, Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte, Facultés de Médecine et de Pharmacie, Clermont-Ferrand, France; and ‖Aix Marseille Université, INSERM UMR_S 911, Faculté de pharmacie, Marseille, France.

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May 2015

Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis.

Gut 2015 Dec 2;64(12):1949-60. Epub 2015 Mar 2.

Inserm, UMR995 - LIRIC, Lille, France Univ Lille, UMR995 - LIRIC, Lille, France CHRU Lille, Service des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Huriez, Lille, France.

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December 2015

Intestinal steroidogenesis.

Steroids 2015 Nov 2;103:64-71. Epub 2015 Jan 2.

Université de Lille, F-59000 Lille, France; Inserm U995, F-59045 Lille, France; Faculté des Sciences Pharmaceutiques et Biologiques, F-59006 Lille, France. Electronic address:

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November 2015

Peroxisome proliferator-activated receptor gamma in the colon: inflammation and innate antimicrobial immunity.

J Clin Gastroenterol 2014 Nov-Dec;48 Suppl 1:S23-7

*INSERM U995 †Université Lille Nord de France ‡CHU Lille, Service des maladies de l'appareil digestif et de la nutrition, Hôpital Claude Huriez, Lille, France.

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June 2015

Intestinal steroidogenesis controls PPARγ expression in the colon and is impaired during ulcerative colitis.

Gut 2015 Jun 22;64(6):901-10. Epub 2014 Jul 22.

Université Lille Nord de France, Lille, France Inserm U995, Lille, France UDSL, Faculté des Sciences Pharmaceutiques et Biologiques, Lille, France.

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June 2015

Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration.

Am J Physiol Gastrointest Liver Physiol 2014 Aug 29;307(3):G274-85. Epub 2014 May 29.

INSERM U995, Lille, France; Université Lille Nord de France, Lille, France; CHU Lille, Service des maladies de l'appareil digestif et de la nutrition, Hôpital Claude Huriez, Lille, France;

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August 2014

Functional polymorphisms in the regulatory regions of the VNN1 gene are associated with susceptibility to inflammatory bowel diseases.

Inflamm Bowel Dis 2013 Oct;19(11):2315-25

1Centre d'Immunologie de Marseille-Luminy (CIML), Aix-Marseille University, Marseille, France; 2Institut National de la Santé et de la Recherche Médicale (Inserm), U1104, Marseille, France; 3Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France; 4Inserm, UMR_S1090, TAGC, Marseille, France; 5Aix-Marseille University, Marseille, France; 6Oncogenetic Laboratory, Institut Paoli Calmettes, Marseille, France; 7Université Lille Nord de France, Lille, France; 8Inserm U995, Lille, France; 9CHU Lille, Service des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Claude, Huriez, Lille, France; 10UDSL, Faculte des Sciences Pharmaceutiques et Biologiques, Lille, France; 11Icahn School of Medicine at Mount Sinai, Mount Sinai, New York; 12Inserm U1080, IRCAN Team 3, Nice, France; 13Université de Nice Sophia Antipolis, Nice, France; and 14Human Tissue Biobank Centre de Ressources Biologiques INSERM, Pasteur Hospital, Nice, France.

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October 2013

PPAR-gamma in ulcerative colitis: a novel target for intervention.

Curr Drug Targets 2013 Nov;14(12):1501-7

Mount Sinai School of Medicine, New York, NY 10029-6574, USA.

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November 2013

Visceral fat and gut inflammation.

Nutrition 2012 Feb;28(2):113-7

Université Lille Nord de France, Lille, France.

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February 2012

Obesity, visceral fat and Crohn's disease.

Curr Opin Clin Nutr Metab Care 2010 Sep;13(5):574-80

Université Lille Nord de France, France.

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September 2010

Peroxisome proliferator-activated receptors in HBV-related infection.

PPAR Res 2009 9;2009:145124. Epub 2009 Apr 9.

Institute National de la Santé et de la recherche Médicale INSERM, U795, 59037 Lille, France.

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September 2012

Peroxisome proliferator-activated receptors in HCV-related infection.

PPAR Res 2009 30;2009:357204. Epub 2009 Mar 30.

Unité INSERM 795, Université Lille 2, Service des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Huriez, CHRU Lille, 59037 Lille, France.

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September 2012

PPARgamma agonists as a new class of effective treatment for ulcerative colitis.

Inflamm Bowel Dis 2009 Jun;15(6):959-60

University of Lille 2, Huriez Hospital, Digestive Tract Diseases and Nutrition Department, Lille, France.

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June 2009

LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.

Proc Natl Acad Sci U S A 2007 Aug 1;104(32):13098-103. Epub 2007 Aug 1.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS, INSERM, Université Louis Pasteur, Illkirch, and Service des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Huriez, Lille, France.

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August 2007

The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine.

J Exp Med 2006 Sep 21;203(9):2057-62. Epub 2006 Aug 21.

Division of Immunopathology, Institute of Pathology, University of Bern, 3010 Bern, Switzerland.

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September 2006

Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation.

Proc Natl Acad Sci U S A 2005 Feb 31;102(6):2058-62. Epub 2005 Jan 31.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique/Institut National de la Santé et de la Recherche Médicale/Université Louis Pasteur, 67404 Illkirch, France.

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February 2005

Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation.

J Clin Invest 2003 May;111(9):1329-38

Equipe Mixte INSERM 0114 sur la Physiopathologie des Maladies Inflammatoires Intestinales, Centre Hospitalier Universitaire, Lille, France.

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May 2003

Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases.

Lancet 2002 Nov;360(9343):1410-8

Equipe Propre INSERM 0114 sur la Physiopathologie des Maladies Inflammatoires Intestinales, Centre Hospitalier Universitaire, Lille, France.

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November 2002