Laurence Zitvogel

Laurence Zitvogel

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Laurence Zitvogel

Publications by authors named "Laurence Zitvogel"

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The intimate relationship between gut microbiota and cancer immunotherapy.

Gut Microbes 2019 19;10(3):424-428. Epub 2018 Oct 19.

a Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM) , Montréal , Qc , Canada.

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https://www.tandfonline.com/doi/full/10.1080/19490976.2018.1
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http://dx.doi.org/10.1080/19490976.2018.1527167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546322PMC
December 2019

Immunostimulatory gut bacteria.

Science 2019 11;366(6469):1077-1078

Suzhou Institute for Systems Biology, Chinese Academy of Medical Sciences, Suzhou, China.

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http://dx.doi.org/10.1126/science.aaz7595DOI Listing
November 2019

Immunosuppression by Mutated Calreticulin Released from Malignant Cells.

Mol Cell 2019 Nov 23. Epub 2019 Nov 23.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France; Sorbonne Université, Paris, France; Université of Paris, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Karolinska Institutet, Department of Women's and Children's Health, Stockholm, Sweden; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.11.004DOI Listing
November 2019

Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies.

Nat Rev Clin Oncol 2019 Oct 8. Epub 2019 Oct 8.

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1038/s41571-019-0272-7DOI Listing
October 2019

Interferon-γ induces cancer cell ferroptosis.

Cell Res 2019 Sep;29(9):692-693

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1038/s41422-019-0186-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796847PMC
September 2019

Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat.

Immunity 2019 09;51(3):423-425

Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Faculty of Medicine, Paris Sud/Paris XI University, Le Kremlin-Bicêtre, France; Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; INSERM U1015, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France.

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http://dx.doi.org/10.1016/j.immuni.2019.08.010DOI Listing
September 2019

Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade.

Oncoimmunology 2019 22;8(10):e1637188. Epub 2019 Jul 22.

Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China.

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http://dx.doi.org/10.1080/2162402X.2019.1637188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791413PMC
July 2019

Trial watch: dendritic cell vaccination for cancer immunotherapy.

Oncoimmunology 2019 18;8(11):e1638212. Epub 2019 Jul 18.

Cell Death Research & Therapy (CDRT) unit, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1080/2162402X.2019.1638212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791419PMC
July 2019

Trial watch: dietary interventions for cancer therapy.

Oncoimmunology 2019 3;8(7):1591878. Epub 2019 Apr 3.

Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2019.1591878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527263PMC
April 2019

Tumor lysis with LTX-401 creates anticancer immunity.

Oncoimmunology 2019 13;8(7):1594555. Epub 2019 Apr 13.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2019.1594555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527292PMC
April 2019

A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers.

Oncoimmunology 2019 26;8(8):1606665. Epub 2019 Apr 26.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2019.1606665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682369PMC
April 2019

CD16NKG2A Natural Killer Cells Infiltrate Breast Cancer-Draining Lymph Nodes.

Cancer Immunol Res 2019 02 4;7(2):208-218. Epub 2018 Dec 4.

INSERM U1160, Institut Universitaire d'Hématologie, Hôpital Saint Louis, Paris, France.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0085DOI Listing
February 2019

Failure of immunosurveillance accelerates aging.

Oncoimmunology 2019 9;8(4):e1575117. Epub 2019 Feb 9.

Equipe 11 labellisée par la Ligue contre le Cancer, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2019.1575117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422365PMC
February 2019

PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade.

Br J Cancer 2019 01 9;120(1):3-5. Epub 2018 Nov 9.

Département d'Innovation Thérapeutique et d'Essais Précoces, Gustave Roussy, Université Paris-Saclay, Villejuif, F-94805, France.

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http://www.nature.com/articles/s41416-018-0294-4
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http://dx.doi.org/10.1038/s41416-018-0294-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325162PMC
January 2019

The impact of the intestinal microbiota in therapeutic responses against cancer.

C R Biol 2018 May - Jun;341(5):284-289. Epub 2018 Apr 7.

U1015 INSERM, université Paris-11, Saclay, Institut Gustave-Roussy, 114, rue Édouard-Vaillant, 94800 Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.crvi.2018.03.004DOI Listing
October 2018

TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves.

Oncoimmunology 2018 1;7(9):e1462431. Epub 2018 Aug 1.

Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2018.1462431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140814PMC
August 2018

Reply to 'Challenging PD-L1 expressing cytotoxic T cells as a predictor for response to immunotherapy in melanoma'.

Nat Commun 2018 07 26;9(1):2922. Epub 2018 Jul 26.

Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, 94805, Villejuif, France.

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http://dx.doi.org/10.1038/s41467-018-05048-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062500PMC
July 2018

Immunogenic and Non-immunogenic Cell Death in the Tumor Microenvironment.

Adv Exp Med Biol 2017 ;1036:65-79

Gustave Roussy Cancer Campus, Villejuif, Cedex, France.

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http://dx.doi.org/10.1007/978-3-319-67577-0_5DOI Listing
June 2018

[Gut microbiota and efficacy of cancer therapies].

Biol Aujourdhui 2017 6;211(1):51-67. Epub 2017 Jul 6.

Gustave Roussy Cancer Campus, 39 rue Camille Desmoulins, 94800 Villejuif, France - Université Paris Saclay, 63 rue Gabriel Péri, 94276 Le Kremlin-Bicêtre, France - Unité INSERM U1015, 114 rue Edouard Vaillant, 94800 Villejuif, France.

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http://dx.doi.org/10.1051/jbio/2017009DOI Listing
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies.

Science 2018 03;359(6382):1366-1370

Department of Pathology, Department of Medicine, and the Ben May Department of Cancer, University of Chicago, Chicago, IL 60615, USA.

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http://dx.doi.org/10.1126/science.aar6918DOI Listing
March 2018

NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis.

Immunity 2018 01 9;48(1):107-119.e4. Epub 2018 Jan 9.

The Lautenberg Center for General and Tumor Immunology, Department of Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University Medical School, Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.12.007DOI Listing
January 2018

Cancer immunotherapy in 2017: The breakthrough of the microbiota.

Nat Rev Immunol 2018 01;18(2):87-88

INSERM U1015, labellisée Ligue Française Contre le Cancer, Université Paris-Saclay, Gustave Roussy Immuno-Oncology Programme, Paris, France.

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http://dx.doi.org/10.1038/nri.2018.4DOI Listing
January 2018

The immune contexture in cancer prognosis and treatment.

Nat Rev Clin Oncol 2017 Dec 25;14(12):717-734. Epub 2017 Jul 25.

Paris Descartes University (Paris 5), Sorbonne Paris Cité, INSERM UMRS 1138, Cordeliers Research Centre.

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http://www.nature.com/doifinder/10.1038/nrclinonc.2017.101
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http://dx.doi.org/10.1038/nrclinonc.2017.101DOI Listing
December 2017

[Chemokine receptors expression on T cells: contribution to diagnosis of melanoma metastasis dissemination status].

Med Sci (Paris) 2016 8-9;32(8-9):690-2. Epub 2016 Sep 12.

Inserm U1015, Gustave Roussy Cancer Campus, 114, rue Edouard Vaillant, 94800 Villejuif, France.

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http://dx.doi.org/10.1051/medsci/20163208010DOI Listing
August 2017

Anticancer effects of the microbiome and its products.

Nat Rev Microbiol 2017 Aug 22;15(8):465-478. Epub 2017 May 22.

Center of Clinical Investigations CIC1428, GRCC, Villejuif 94805, France.

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http://www.nature.com/doifinder/10.1038/nrmicro.2017.44
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http://dx.doi.org/10.1038/nrmicro.2017.44DOI Listing
August 2017

Nutrition, inflammation and cancer.

Nat Immunol 2017 Jul;18(8):843-850

Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1038/ni.3754DOI Listing
July 2017

Reply: Immunosuppressive cell death in cancer.

Nat Rev Immunol 2017 06 8;17(6):402. Epub 2017 May 8.

Université Paris Descartes/Paris V, Sorbonne Paris Cité, 75006 Paris, France; Université Pierre et Marie Curie/Paris VI, 75006 Paris; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France; at INSERM, U1138, 75006 Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, 94805 Villejuif, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, 17176 Stockholm, Sweden; and at Pôle de Biologie, Hopitâl Européen George Pompidou, AP-HP; 75015 Paris, France.

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http://dx.doi.org/10.1038/nri.2017.48DOI Listing
June 2017

Immunogenic cell death in cancer and infectious disease.

Nat Rev Immunol 2017 02 17;17(2):97-111. Epub 2016 Oct 17.

Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France.

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http://dx.doi.org/10.1038/nri.2016.107DOI Listing
February 2017

Reply: The complement system is also important in immunogenic cell death.

Nat Rev Immunol 2017 02 28;17(2):143. Epub 2016 Dec 28.

Equipe 11 Labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France; INSERM, U1138, 75006 Paris, France; Université Pierre et Marie Curie/Paris VI, 75006 Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, 94805 Villejuif, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, 17176 Stockholm, Sweden; and Pôle de Biologie, Hopitâl Européen George Pompidou, AP-HP; 75015 Paris, France.

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http://dx.doi.org/10.1038/nri.2016.143DOI Listing
February 2017

Mouse models in oncoimmunology.

Nat Rev Cancer 2016 12 30;16(12):759-773. Epub 2016 Sep 30.

Equipe 11 labelisée par la Ligue Nationale contre le Cancer, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France.

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http://dx.doi.org/10.1038/nrc.2016.91DOI Listing
December 2016

Immunological Mechanisms Underneath the Efficacy of Cancer Therapy.

Cancer Immunol Res 2016 11;4(11):895-902

Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1158/2326-6066.CIR-16-0197DOI Listing
November 2016

[The role of intestinal microbiota in the response to anti-tumor therapies].

Med Sci (Paris) 2016 Nov 23;32(11):974-982. Epub 2016 Dec 23.

Gustave Roussy cancer campus, 114, rue Édouard Vaillant, 94800 Villejuif, France - Université Paris-Saclay, Le Kremlin-Bicêtre, France - Unité Inserm U1015, 94800 Villejuif, France.

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http://dx.doi.org/10.1051/medsci/20163211013DOI Listing
November 2016

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects.

Immunity 2016 10 4;45(4):931-943. Epub 2016 Oct 4.

Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, Villejuif, 94805, France; Institut National de la Santé Et de la Recherche Medicale (INSERM), U1015, GRCC, Villejuif, 94805, France; University of Paris-Saclay, Kremlin Bicêtre, 94270, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, 94805, France. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.09.009DOI Listing
October 2016

Fine-Tuning Cancer Immunotherapy: Optimizing the Gut Microbiome.

Cancer Res 2016 08 29;76(16):4602-7. Epub 2016 Jul 29.

Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), Villejuif, France. INSERM Unit U1015, Villejuif, France. Université Paris Sud, Université Paris-Saclay, Faculté de Médecine, Le Kremlin Bicêtre, France. Center of Clinical Investigations CICBT1428, Gustave Roussy Cancer Campus, 94805, Villejuif, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0448DOI Listing
August 2016

The ratio of CD8/FOXP3 T lymphocytes infiltrating breast tissues predicts the relapse of ductal carcinoma .

Oncoimmunology 2016 18;5(10):e1218106. Epub 2016 Aug 18.

Gustave Roussy Cancer Campus, Villejuif, France; INSERM, U1138, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Center de Recherche des Cordeliers, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1080/2162402X.2016.1218106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087306PMC
August 2016

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance.

Cancer Cell 2016 07;30(1):147-160

Gustave Roussy Cancer Campus, 94800 Villejuif, France; INSERM, U1138, 75006 Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, 75006 Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800 Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, 75015 Paris, France; Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden; INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715805PMC
July 2016

Calreticulin expression: Interaction with the immune infiltrate and impact on survival in patients with ovarian and non-small cell lung cancer.

Oncoimmunology 2016 Jul 9;5(7):e1177692. Epub 2016 Jun 9.

Université Paris Descartes, Sorbonne Paris Cité, 15 rue de l'Ecole de Médecine, Paris, France; Université Pierre et Marie Curie, 15 rue de l'Ecole de Médecine, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1080/2162402X.2016.1177692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006900PMC
July 2016

Trial Watch: Immunotherapy plus radiation therapy for oncological indications.

Oncoimmunology 2016 25;5(9):e1214790. Epub 2016 Jul 25.

INSERM, U1138, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Center de Recherche des Cordeliers, Paris, France; Gustave Roussy Cancer Campus, Villejuif, France; Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1214790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048768PMC
July 2016

Impact of Pattern Recognition Receptors on the Prognosis of Breast Cancer Patients Undergoing Adjuvant Chemotherapy.

Cancer Res 2016 06 16;76(11):3122-6. Epub 2016 May 16.

Gustave Roussy Cancer Campus, Villejuif, France. INSERM, U1138, Paris, France. Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France. Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Université Pierre et Marie Curie, Paris, France. Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France. Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France. Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0294DOI Listing
June 2016

Unchaining NK cell-mediated anticancer immunosurveillance.

Nat Immunol 2016 06;17(7):746-7

Gustave Roussy Cancer Campus, Villejuif, France, Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Paris, France, Université Pierre &Marie Curie, Paris, France, Metabolomics and Cell Biology Platforms, Gustave Roussy, Villejuif, France, Pôle de Biologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Paris, France, and Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1038/ni.3471DOI Listing
June 2016

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors.

Immunity 2016 06;44(6):1255-69

Institut de Cancérologie, Gustave Roussy Cancer Campus, 94800 Villejuif, France; INSERM U1015, 94800 Villejuif, France; Faculté de Médecine, Université Paris Sud, Université Paris-Saclay, 94276 Le Kremlin Bicêtre, France; Center of Clinical Investigations CICBT1428, Gustave Roussy Cancer Campus, 94805 Villejuif Cedex 05, France. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.06.001DOI Listing
June 2016

Inhibition of formyl peptide receptor 1 reduces the efficacy of anticancer chemotherapy against carcinogen-induced breast cancer.

Oncoimmunology 2016 Jun 18;5(6):e1139275. Epub 2016 Feb 18.

Gustave Roussy Cancer Campus, Villejuif, France; INSERM, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1080/2162402X.2016.1139275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938360PMC
June 2016

Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy.

Oncoimmunology 2016 Jun 10;5(6):e1149673. Epub 2016 Mar 10.

Equipe 11 labellisée Ligue contre le Cancer, Center de Recherche des Cordeliers, Institut National de la Santé Et de la Recherche Medicale (INSERM) U 1138, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), Villejuif, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1080/2162402X.2016.1149673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938314PMC
June 2016

Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.

Oncoimmunology 2016 Jun 10;5(6):e1149674. Epub 2016 Mar 10.

INSERM, U1138, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2016.1149674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938376PMC
June 2016

Biomarkers of immunogenic stress in metastases from melanoma patients: Correlations with the immune infiltrate.

Oncoimmunology 2016 Jun 16;5(6):e1160193. Epub 2016 Mar 16.

Equipe 11 labellisée pas la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; INSERM, U1138, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1080/2162402X.2016.1160193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938307PMC
June 2016

Positive impact of autophagy in human breast cancer cells on local immunosurveillance.

Oncoimmunology 2016 Jun 24;5(6):e1174801. Epub 2016 May 24.

Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Université Pierre et Marie Curie, Paris, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Paris, France; Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden; INSERM, U1138, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2016.1174801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938361PMC
June 2016

Yet another pattern recognition receptor involved in the chemotherapy-induced anticancer immune response: Formyl peptide receptor-1.

Oncoimmunology 2016 May 30;5(5):e1118600. Epub 2016 Mar 30.

Gustave Roussy Cancer Campus, Villejuif, France; INSERM, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1080/2162402X.2015.1118600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910768PMC
May 2016

STAT3 inhibition for cancer therapy: Cell-autonomous effects only?

Oncoimmunology 2016 May 8;5(5):e1126063. Epub 2016 Jan 8.

Gustave Roussy Comprehensive Cancer Center, Villejuif, France; INSERM, U1015, Equipe labellisé e Ligue Nationale Contre le Cancer, Villejuif, France; University of Paris Sud/Paris XI, Le Kremlin-Bicêtre, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 507, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1126063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910743PMC
May 2016

Prognostic impact of the expression of NCR1 and NCR3 NK cell receptors and PD-L1 on advanced non-small cell lung cancer.

Oncoimmunology 2017 13;6(1):e1163456. Epub 2016 May 13.

Gustave Roussy Cancer Campus (GRCC), Villejuif, France; INSERM, GRCC, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT), GRCC, Villejuif, France; University of Paris Sud XI, Kremlin Bicêtre, France; Department of Immuno-Oncology, GRCC, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2016.1163456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283624PMC
May 2016

Microbiome and Anticancer Immunosurveillance.

Cell 2016 Apr;165(2):276-87

Equipe 11 labellisée par la Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France; Cell Biology and Metabolomics platforms, Gustave Roussy Comprehensive Cancer Center, 95800 Villejuif, France; INSERM, U1138, 75006 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France; Université Pierre et Marie Curie, 75006 Paris, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, 75015 Paris, France; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, 17176 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.03.001DOI Listing
April 2016

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC.

Oncoimmunology 2016 Apr 12;5(4):e1071008. Epub 2015 Aug 12.

Gustave Roussy Cancer Campus, Villejuif, France; Laboratoire d'Immunomonitoring en Oncologie, UMS 3655 CNRS / US 23 INSERM Gustave Roussy Cancer Campus, Villejuif, France; Centre d'Investigation Clinique en Biothérapies (CICBT) 1428, Villejuif, France; Laboratoire de Thérapie Cellulaire, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1071008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839329PMC
April 2016

Prime time for immune-checkpoint targeted therapy at ASCO 2015.

Oncoimmunology 2016 Mar 12;5(3):e1068494. Epub 2015 Aug 12.

Gustave Roussy Cancer Campus, Villejuif, France; INSERM, U1015, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1068494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839368PMC
March 2016

Trial Watch: Immunostimulation with Toll-like receptor agonists in cancer therapy.

Oncoimmunology 2016 Mar 2;5(3):e1088631. Epub 2015 Sep 2.

INSERM, U1138, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Gustave Roussy Cancer Campus, Villejuif, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Center de Recherche des Cordeliers, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2015.1088631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839356PMC
March 2016

Trial Watch-Oncolytic viruses and cancer therapy.

Oncoimmunology 2016 Feb 8;5(2):e1117740. Epub 2015 Dec 8.

INSERM, U1138, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Center de Recherche des Cordeliers, Paris, France; Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1117740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801444PMC
February 2016

Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut microbiota.

Oncoimmunology 2017 18;6(1):e1132137. Epub 2016 Feb 18.

Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), Villejuif, France; INSERM Unit U1015, Villejuif, France; Faculté de Médecine, Université Paris Sud, Université Paris-Saclay, Le Kremlin Bicêtre, France; INSERM Unit U932, Institut Curie, Paris Cedex 05, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 507, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2015.1132137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283646PMC
February 2016