Publications by authors named "Laurence Klotz"

100Publications

Trends in urologic oncology clinical practice and medical education under COVID-19 pandemic: An international survey of senior clinical and academic urologists.

Urol Oncol 2020 Oct 7. Epub 2020 Oct 7.

Department of Urology, Chaim Sheba Medical Center, Ramat Gan, Israel, The Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.

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http://dx.doi.org/10.1016/j.urolonc.2020.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539173PMC
October 2020

When to biopsy Prostate Imaging and Data Reporting System version 2 (PI-RADSv2) assessment category 3 lesions? Use of clinical and imaging variables to predict cancer diagnosis at targeted biopsy.

Can Urol Assoc J 2020 Sep 28. Epub 2020 Sep 28.

Division of Urology, Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.6781DOI Listing
September 2020

Patients' perspective of telephone visits during the COVID-19 pandemic.

Can Urol Assoc J 2020 Sep;14(9):E402-E406

Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.6758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492037PMC
September 2020

Scoping review: hotspots for COVID-19 urological research: what is being published and from where?

World J Urol 2020 Sep 9. Epub 2020 Sep 9.

Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00345-020-03434-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480207PMC
September 2020

Active surveillance for low-risk prostate cancer - in pursuit of a standardized protocol.

Cent European J Urol 2020 25;73(2):123-126. Epub 2020 Jun 25.

Division of Urology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.5173/ceju.2020.0167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407781PMC
June 2020

Intermittent versus continuous androgen deprivation therapy for advanced prostate cancer.

Nat Rev Urol 2020 Aug 30;17(8):469-481. Epub 2020 Jun 30.

Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/s41585-020-0335-7DOI Listing
August 2020

The history of intermittent androgen deprivation therapy - A Canadian story.

Authors:
Laurence Klotz

Can Urol Assoc J 2020 Jun;14(6):159-162

University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.6601DOI Listing
June 2020

Impact of COVID-19 on Urology Practice: A Global Perspective and Snapshot Analysis.

J Clin Med 2020 Jun 3;9(6). Epub 2020 Jun 3.

Department of Urology, Istanbul Medipol University, Istanbul 34214, Turkey.

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http://dx.doi.org/10.3390/jcm9061730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356721PMC
June 2020

Systematic review and meta-analysis of trials evaluating the role of adjuvant radiation after radical prostatectomy for prostate cancer: Implications for early salvage.

Can Urol Assoc J 2020 May 12. Epub 2020 May 12.

Division of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.6440DOI Listing
May 2020

Impact of Biopsy Compliance on Outcomes for Patients on Active Surveillance for Prostate Cancer.

J Urol 2020 Nov 24;204(5):934-940. Epub 2020 Apr 24.

Department of Radiation Oncology, Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/JU.0000000000001091DOI Listing
November 2020

Intermediate-risk Prostate Cancer: Stratification and Management.

Eur Urol Oncol 2020 Jun 14;3(3):270-280. Epub 2020 Apr 14.

Department of Radiation Oncology, Brigham and Women's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.euo.2020.03.002DOI Listing
June 2020

A Systematic Review and Network Meta-analysis of Novel Androgen Receptor Inhibitors in Non-metastatic Castration-resistant Prostate Cancer.

Clin Genitourin Cancer 2020 Oct 6;18(5):343-350. Epub 2020 Mar 6.

Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2020.02.005DOI Listing
October 2020

Reply by Authors.

J Urol 2020 06 16;203(6):1093. Epub 2020 Mar 16.

Urology Division, Surgical Oncology Department, Princess Margaret Cancer Center, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/JU.0000000000000595.02DOI Listing
June 2020

Testosterone Breakthrough Rates during Androgen Deprivation Therapy for Castration Sensitive Prostate Cancer.

J Urol 2020 Sep 25;204(3):416-426. Epub 2020 Feb 25.

Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/JU.0000000000000809DOI Listing
September 2020

Can high resolution micro-ultrasound replace MRI in the diagnosis of prostate cancer?

Eur Urol Focus 2020 03 24;6(2):419-423. Epub 2019 Nov 24.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2019.11.006DOI Listing
March 2020

Active surveillance in intermediate-risk prostate cancer.

Authors:
Laurence Klotz

BJU Int 2020 03 16;125(3):346-354. Epub 2020 Jan 16.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/bju.14935DOI Listing
March 2020

Apalutamide for Metastatic, Hormone-Responsive Prostate Cancer.

Authors:
Laurence Klotz

N Engl J Med 2019 07;381(1):84-86

From the Sunnybrook Health Sciences Centre, Toronto.

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http://dx.doi.org/10.1056/NEJMe1905891DOI Listing
July 2019

Consistent Biopsy Quality and Gleason Grading Within the Global Active Surveillance Global Action Plan 3 Initiative: A Prerequisite for Future Studies.

Eur Urol Oncol 2019 05 13;2(3):333-336. Epub 2018 Sep 13.

Erasmus Medical Center, Rotterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S25889311183013
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http://dx.doi.org/10.1016/j.euo.2018.08.017DOI Listing
May 2019

Advanced Androgen Blockage in Nonmetastatic Castration-resistant Prostate Cancer: An Indirect Comparison of Apalutamide and Enzalutamide.

Eur Urol Oncol 2018 08 15;1(3):238-241. Epub 2018 May 15.

Division of Urology, Department of Surgery, University of Toronto, Toronto, Canada; Division of Urology, Department of Surgery, Princess Margaret Hospital, University Health Network, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S25889311183003
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http://dx.doi.org/10.1016/j.euo.2018.04.004DOI Listing
August 2018

Contemporary approach to active surveillance for favorable risk prostate cancer.

Authors:
Laurence Klotz

Asian J Urol 2019 Apr 15;6(2):146-152. Epub 2018 Dec 15.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S22143882183009
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http://dx.doi.org/10.1016/j.ajur.2018.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488691PMC
April 2019

Active surveillance in intermediate risk prostate cancer.

Arch Esp Urol 2019 Mar;72(2):157-166

Division of Urology. Sunnybrook Health Sciences Centre. Toronto. ON. Canada.

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March 2019

Re: Prostate Cancer-specific Mortality Across Gleason Scores in Black vs Nonblack Men.

Eur Urol 2019 06 26;75(6):1036-1037. Epub 2019 Feb 26.

Department of Surgery, Division of Urology, Medical College of Georgia at Augusta University, Augusta, GA, USA; Georgia Cancer Center at Augusta University, Augusta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2019.02.019DOI Listing
June 2019

Combining urinary DNA methylation and cell-free microRNA biomarkers for improved monitoring of prostate cancer patients on active surveillance.

Urol Oncol 2019 05 16;37(5):297.e9-297.e17. Epub 2019 Feb 16.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2019.01.031DOI Listing
May 2019

Value of Increasing Biopsy Cores per Target with Cognitive MRI-targeted Transrectal US Prostate Biopsy.

Radiology 2019 04 29;291(1):83-89. Epub 2019 Jan 29.

From the Department of Medical Imaging (M.Z., L.M., M.A.H.), Division of Anatomic Pathology (L.S., M.D.), and Department of Surgery (L.K.), Sunnybrook Health Sciences Centre, Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada (L.M., F.K., S.M.B., L.K.); Ontario Institute for Cancer Research, Toronto, Canada (M.A.H.); Department of Medical Imaging, Mount Sinai Hospital, University of Toronto, 600 University Ave, 5th Floor, Toronto, ON, Canada M5G 1X5 (M.A.H.); and Lunenfeld Tanenbaum Research Institute, Toronto, Canada (M.A.H.).

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http://pubs.rsna.org/doi/10.1148/radiol.2019180712
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http://dx.doi.org/10.1148/radiol.2019180712DOI Listing
April 2019

Discordance between testosterone measurement methods in castrated prostate cancer patients.

Endocr Connect 2019 Feb;8(2):132-140

Division of Urology, Department of Surgery and Cancer Research Center, Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Québec, Québec, Canada.

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http://dx.doi.org/10.1530/EC-18-0476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376995PMC
February 2019

A Phase 1 Pilot Study of Preoperative Radiation Therapy for Prostate Cancer: Long-Term Toxicity and Oncologic Outcomes.

Int J Radiat Oncol Biol Phys 2019 05 6;104(1):61-66. Epub 2019 Jan 6.

Department of Radiation Oncology, University of Toronto, Toronto, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Techna Institute, University Health Network, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.12.054DOI Listing
May 2019

Combining Desmopressin and Docetaxel for the Treatment of Castration-Resistant Prostate Cancer in an Orthotopic Model.

Anticancer Res 2019 Jan;39(1):113-118

Department of Surgery, Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada

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http://dx.doi.org/10.21873/anticanres.13086DOI Listing
January 2019

Oncologic and Functional Outcomes of Partial Gland Ablation with High Intensity Focused Ultrasound for Localized Prostate Cancer.

J Urol 2019 01;201(1):113-119

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00225347184355
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http://dx.doi.org/10.1016/j.juro.2018.07.040DOI Listing
January 2019

Cannabinoid WIN 55,212-2 induces cell cycle arrest and apoptosis, and inhibits proliferation, migration, invasion, and tumor growth in prostate cancer in a cannabinoid-receptor 2 dependent manner.

Prostate 2019 02 21;79(2):151-159. Epub 2018 Sep 21.

Department of Surgery (Urology), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pros.23720DOI Listing
February 2019

Oncologic and Functional Outcomes of Partial Gland Ablation with High Intensity Focused Ultrasound for Localized Prostate Cancer.

J Urol 2019 01;201(1):113-119

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto , Toronto , Ontario , Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00225347184355
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http://dx.doi.org/10.1016/j.juro.2018.07.040DOI Listing
January 2019

Stratifying Risk for Men With Low-Volume Intermediate-Risk Prostate Cancer.

Authors:
Laurence Klotz

JAMA Oncol 2018 08;4(8):1133

Division of Urology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaoncol.2018.0748DOI Listing
August 2018

The future of active surveillance.

Authors:
Laurence Klotz

Transl Androl Urol 2018 Apr;7(2):256-259

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.21037/tau.2018.01.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911542PMC
April 2018

Prostate cancer prevention: proof is elusive.

Authors:
Laurence Klotz

BJU Int 2018 04;121(4):487-488

Division of Urology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/bju.14184DOI Listing
April 2018

MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis.

N Engl J Med 2018 May 18;378(19):1767-1777. Epub 2018 Mar 18.

From University College London (UCL) and UCL Hospitals NHS Foundation Trust (V.K., C.A., F.G., A.F., S.M., S.P., M.E., C.M.M.), London North West Healthcare NHS Trust (G.H.), Whittington Health NHS Trust (M.G.), Royal Free London NHS Foundation Trust (P.B.S.), and UCL Surgical and Interventional Trials Unit (N.R.W., C.B.-G.), London, Hampshire Hospitals NHS Foundation Trust, Basingstoke (R.G.H.), Princess Alexandra Hospital NHS Trust, Harlow (J.V.), and the Institute of Applied Health Research and the NIHR Birmingham Biomedical Research Centre, University of Birmingham, Birmingham (J.D., Y.T.) - all in the United Kingdom; Helsinki University and Helsinki University Hospital, Helsinki (A.S.R.), and Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu (M.H.V.) - all in Finland; Centro de Urología, Buenos Aires (M.B.); Sapienza University, Rome (V.P.), and IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milan (A.B.) - all in Italy; Mayo Clinic, Rochester, MN (L.A.M.); Martini Klinik, Hamburg (L.B.), University Hospital Essen, Essen (B.A.H.), and University Hospital Heidelberg, Heidelberg (B.A.H.) - all in Germany; Erasmus University Medical Center, Rotterdam (M.J.R.), and Radboud University Medical Center, Nijmegen (W.V.) - both in the Netherlands; University of Chicago, Chicago (S.E.); Université de Lille and Centre Hospitalier Universitaire Lille, Lille (A.V.), Université de Bordeaux and Bordeaux Pellegrin University Hospital, Bordeaux (G.R.), and Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud (A.R.), and Hospices Civils de Lyon of the Hôpital Edouard Herriot (S.C.), Lyon - all in France; Jewish General Hospital, Montreal (F.B.), and Sunnybrook Health Sciences Centre, Toronto (L.K.) - both in Canada; Ghent University Hospital, Ghent, Belgium (G.M.V.); University Hospital Bern, Bern, Switzerland (S.B.); Weill Cornell Medicine, New York-Presbyterian Hospital (J.C.H., D.M.), and New York University Langone Medical Center (S.S.T.), New York; National Institutes of Health, Bethesda, MD (P.P.); and the University of Southern California Institute of Urology, Keck School of Medicine, Los Angeles (I.G.).

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http://dx.doi.org/10.1056/NEJMoa1801993DOI Listing
May 2018

Personal prostate-specific antigen screening and treatment choices for localized prostate cancer among expert physicians.

Can Urol Assoc J 2018 Feb 1;12(2):E59-E63. Epub 2017 Dec 1.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.4736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937408PMC
February 2018

Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Part II: Recommended Approaches and Details of Specific Care Options.

J Urol 2018 04 10;199(4):990-997. Epub 2018 Jan 10.

American Urological Association Education and Research, Inc., Linthicum, Maryland; ASTRO, Arlington, Virginia; Society of Urologic Oncology, Schamburg, Illinois.

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http://dx.doi.org/10.1016/j.juro.2018.01.002DOI Listing
April 2018

A single mitochondrial DNA deletion accurately detects significant prostate cancer in men in the PSA 'grey zone'.

World J Urol 2018 Mar 16;36(3):341-348. Epub 2017 Dec 16.

Academic Urology Group, Department of Surgery and Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s00345-017-2152-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846823PMC
March 2018

Assessment of Serum microRNA Biomarkers to Predict Reclassification of Prostate Cancer in Patients on Active Surveillance.

J Urol 2018 06 12;199(6):1475-1481. Epub 2017 Dec 12.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225347177806
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http://dx.doi.org/10.1016/j.juro.2017.12.006DOI Listing
June 2018

Total energy expenditure and vigorous-intensity physical activity are associated with reduced odds of reclassification among men on active surveillance.

Prostate Cancer Prostatic Dis 2018 06 14;21(2):187-195. Epub 2017 Dec 14.

Division of Urology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41391-017-0010-0DOI Listing
June 2018

Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Part I: Risk Stratification, Shared Decision Making, and Care Options.

J Urol 2018 03 15;199(3):683-690. Epub 2017 Dec 15.

American Urological Association Education and Research, Inc., Linthicum, Maryland; ASTRO, Arlington, Virginia; Society of Urologic Oncology, Schamburg, Illinois.

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http://dx.doi.org/10.1016/j.juro.2017.11.095DOI Listing
March 2018

Evaluating Metformin as a Potential Chemosensitizing Agent when Combined with Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Cells.

Anticancer Res 2017 12;37(12):6601-6607

Division of Urology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

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http://dx.doi.org/10.21873/anticanres.12117DOI Listing
December 2017

Comparative Analysis of Biopsy Upgrading in Four Prostate Cancer Active Surveillance Cohorts.

Ann Intern Med 2018 01 28;168(1):1-9. Epub 2017 Nov 28.

From University of Washington, Seattle, Washington; Fred Hutchinson Cancer Research Center, Seattle, Washington; Technical University of Munich, Garching, Germany; The James Buchanan Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland; University of California, San Francisco, San Francisco, California; University of Toronto, Toronto, Ontario, Canada; and Vanderbilt University, Nashville, Tennessee.

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http://dx.doi.org/10.7326/M17-0548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752581PMC
January 2018

Contemporary Active Surveillance: Candidate Selection, Follow-up Tools, and Expected Outcomes.

Urol Clin North Am 2017 Nov;44(4):565-574

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue. # MG 408, Toronto, Ontario M4N3M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ucl.2017.07.005DOI Listing
November 2017

Prostatectomy versus Observation for Early Prostate Cancer.

N Engl J Med 2017 09;377(13):1301-2

Sunnybrook Health Sciences Centre, Toronto, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1710384DOI Listing
September 2017

Active Surveillance for Intermediate Risk Prostate Cancer.

Authors:
Laurence Klotz

Curr Urol Rep 2017 Aug 11;18(10):80. Epub 2017 Aug 11.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave. #MG408, Toronto, Ontario, M4N 3M5, Canada.

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http://link.springer.com/10.1007/s11934-017-0726-3
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http://dx.doi.org/10.1007/s11934-017-0726-3DOI Listing
August 2017

Active Surveillance for Prostate Cancer: How to Do It Right.

Oncology (Williston Park) 2017 05;31(5):333-40, 345

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May 2017

Maximal testosterone suppression in the management of recurrent and metastatic prostate cancer.

Can Urol Assoc J 2017 Jan-Feb;11(1-2):E62-E63. Epub 2017 Feb 20.

Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.5489/cuaj.4494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403685PMC
February 2017

The drama of prostate cancer diagnostics.

Lancet Oncol 2017 03 2;18(3):e132. Epub 2017 Mar 2.

Department of Urology/CamPARI Clinic, Cambridge University Hospitals, Cambridge, UK; Academic Urology Group, Department of Surgery, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1016/S1470-2045(17)30121-3DOI Listing
March 2017

Active surveillance for low-risk prostate cancer.

Authors:
Laurence Klotz

Curr Opin Urol 2017 May;27(3):225-230

Division of Urology Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MOU.0000000000000393DOI Listing
May 2017

10-Year Outcomes in Localized Prostate Cancer.

N Engl J Med 2017 01;376(2):178

Brigham and Women’s Hospital, Boston, MA

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http://dx.doi.org/10.1056/NEJMc1614342DOI Listing
January 2017

The Effect of Metformin Use during Docetaxel Chemotherapy on Prostate Cancer Specific and Overall Survival of Diabetic Patients with Castration Resistant Prostate Cancer.

J Urol 2017 04 28;197(4):1068-1075. Epub 2016 Oct 28.

Division of Urology, Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.10.069DOI Listing
April 2017

The uptake of active surveillance for the management of prostate cancer: A population-based analysis.

Can Urol Assoc J 2016 Sep-Oct;10(9-10):E342-E346. Epub 2016 Oct 13.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto.

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http://dx.doi.org/10.5489/cuaj.4207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085922PMC
October 2016

The uptake of active surveillance for the management of prostate cancer: A population-based analysis.

Can Urol Assoc J 2016 Sep-Oct;10(9-10):333-338

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto.

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http://dx.doi.org/10.5489/cuaj.3684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085913PMC
November 2016

Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance.

J Urol 2017 02 18;197(2):335-341. Epub 2016 Aug 18.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Pathology, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.08.081DOI Listing
February 2017

Active Surveillance for Intermediate Risk Prostate Cancer: Survival Outcomes in the Sunnybrook Experience.

J Urol 2016 12 26;196(6):1651-1658. Epub 2016 Aug 26.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Measurement and Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.06.102DOI Listing
December 2016

Intermittent Androgen Deprivation Therapy-An Important Treatment Option for Prostate Cancer.

JAMA Oncol 2016 Dec;2(12):1531-1532

Division of Medical Oncology, Departments of Medicine and Urology, University of Washington School of Medicine, Fred Hutchinson Cancer Research Center, Seattle.

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http://dx.doi.org/10.1001/jamaoncol.2016.3138DOI Listing
December 2016

Laurence Klotz on the Controversy Surrounding Screening for Prostate Cancer.

Authors:
Laurence Klotz

Oncology (Williston Park) 2016 08;30(8):694, 764

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August 2016

Testosterone Therapy Can be Given to Men with No Concern that it will Promote Prostate Cancer Development or Progression: Con.

J Urol 2016 10 9;196(4):985-8. Epub 2016 Aug 9.

Department of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2016.08.010DOI Listing
October 2016

Surgery Provides Better Oncologic Outcomes than Radiation for the Treatment of Prostate Cancer.

J Urol 2016 08 7;196(2):309-11. Epub 2016 May 7.

Department of Urology, University of California, Davis School of Medicine, Sacramento, California.

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http://dx.doi.org/10.1016/j.juro.2016.05.008DOI Listing
August 2016

Active surveillance and focal therapy for low-intermediate risk prostate cancer.

Authors:
Laurence Klotz

Transl Androl Urol 2015 Jun;4(3):342-54

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Canada.

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http://dx.doi.org/10.3978/j.issn.2223-4683.2015.06.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708232PMC
June 2015

Overtreatment in cancer - is it a problem?

Expert Opin Pharmacother 2016 20;17(1):1-5. Epub 2016 Jan 20.

a Division of Urology , Sunnybrook Health Sciences Centre , Toronto , ON , Canada.

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http://dx.doi.org/10.1517/14656566.2016.1115481DOI Listing
June 2016