Laurence J N Cooper

Laurence J N Cooper

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Laurence J N Cooper

Publications by authors named "Laurence J N Cooper"

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Etiologies and Impact of Readmission Rates in the First 180 Days After Hematopoietic Stem Cell Transplantation in Children, Adolescents, and Young Adults.

J Pediatr Hematol Oncol 2017 11;39(8):609-613

*Division of Pediatrics Departments of ‡Stem Cell Transplantation and Cellular Therapy §Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX †Department of Pediatrics, The National Cancer Institute, Cairo University, Cairo, Egypt.

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https://journals.lww.com/jpho-online/toc/2017/11000
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http://Insights.ovid.com/crossref?an=00043426-201711000-0000
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http://dx.doi.org/10.1097/MPH.0000000000000898DOI Listing
November 2017

Targeting B-cell malignancies through human B-cell receptor specific CD4 T cells.

Oncoimmunology 2016 19;5(11):e1232220. Epub 2016 Sep 19.

Department of Lymphoma and Myeloma, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center , Houston, TX, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1232220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139634PMC
September 2016

Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor.

J Immunother 2016 06;39(5):205-17

*Division of Pediatrics Departments of ‡Biostatistics ∥Neurosurgery §Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center †The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX.

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http://dx.doi.org/10.1097/CJI.0000000000000126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847343PMC
June 2016

T cells expressing CD19-specific Engager Molecules for the Immunotherapy of CD19-positive Malignancies.

Sci Rep 2016 06 3;6:27130. Epub 2016 Jun 3.

Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/srep27130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891739PMC
June 2016

Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations.

PLoS One 2015 1;10(6):e0128151. Epub 2015 Jun 1.

Pediatrics, Children's Cancer Hospital, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America; University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128151PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451012PMC
April 2016

Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma.

J Immunother 2014 Nov-Dec;37(9):448-60

*Department of Melanoma Medical Oncology †Division of Pediatrics, MD Anderson Cancer Center, Houston, TX ‡Infectious Disease and Immunogenetics Section, Department of Transfusion Medicine, Clinical Center and trans-NIH Center for Human Immunology, National Institutes of Health, Bethesda, MD ∥Lion Biotechnologies, Woodland Hills, CA §Sidra Medical and Research Hospital, Doha, Qatar.

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http://dx.doi.org/10.1097/CJI.0000000000000056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199393PMC
November 2015

Haploidentical Hematopoietic Stem Cell Transplantation as a Platform for Post-Transplantation Cellular Therapy.

Biol Blood Marrow Transplant 2015 Oct 11;21(10):1714-20. Epub 2015 Jul 11.

Department of Stem Cell Transplantation and Cellular Therapy, University of Texas, MD Anderson Cancer Center, Houston, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791150045
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http://dx.doi.org/10.1016/j.bbmt.2015.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825320PMC
October 2015

Dihydrofolate Reductase and Thymidylate Synthase Transgenes Resistant to Methotrexate Interact to Permit Novel Transgene Regulation.

J Biol Chem 2015 Sep 4;290(38):22970-6. Epub 2015 Aug 4.

From the Division of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center (MDACC), Houston, Texas 77030 and the The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas 77030

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http://dx.doi.org/10.1074/jbc.C115.671123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645590PMC
September 2015

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity.

Cancer Res 2015 Sep;75(17):3505-18

Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624228PMC
September 2015

Genetic Engineering of T Cells to Target HERV-K, an Ancient Retrovirus on Melanoma.

Clin Cancer Res 2015 Jul 31;21(14):3241-51. Epub 2015 Mar 31.

Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas. University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-3197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506228PMC
July 2015

Clinical applications of gamma delta T cells with multivalent immunity.

Front Immunol 2014 11;5:636. Epub 2014 Dec 11.

Division of Pediatrics, University of Texas MD Anderson Cancer Center , Houston, TX , USA ; The University of Texas Graduate School of Biomedical Sciences, UT MD Anderson Cancer Center , Houston, TX , USA.

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http://journal.frontiersin.org/article/10.3389/fimmu.2014.00
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http://dx.doi.org/10.3389/fimmu.2014.00636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263175PMC
January 2015

Epidermal growth factor receptor and variant III targeted immunotherapy.

Neuro Oncol 2014 Oct;16 Suppl 8:viii20-5

The Preston Robert Tisch Brain Tumor Center (K.L.C., P.C.G., C.M.S., J.H.S.); Division of Neurosurgery, Department of Surgery, Duke University Medical Center Durham, North Carolina (K.L.C., P.C.G., C.M.S., J.H.S.); Department of Biomedical Engineering, Duke University Durham, North Carolina (P.C.G.); Department of Pathology, Duke University Medical Center Durham, North Carolina (J.H.S.); Department of Immunology, The University of Texas M.D. Anderson Cancer Center Houston, Texas (H.G.C., L.J.N.C.); Division of Pediatrics, The University of Texas M.D. Anderson Cancer Center Houston, Texas (H.G.C., L.J.N.C.); Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center Houston, Texas (A.B.H.).

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http://dx.doi.org/10.1093/neuonc/nou236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207138PMC
October 2014

The human application of gene therapy to re-program T-cell specificity using chimeric antigen receptors.

Chin J Cancer 2014 Sep;33(9):421-33

Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.cjcsysu.cn/abstract.asp?fr=doi&idno=21099
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http://dx.doi.org/10.5732/cjc.014.10100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190432PMC
September 2014

Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.

Nat Commun 2014 Aug 7;5:4577. Epub 2014 Aug 7.

1] Lester &Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas 77030, USA [2] Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA [3] Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA [4] Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://www.nature.com/articles/ncomms5577
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http://dx.doi.org/10.1038/ncomms5577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130357PMC
August 2014

Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity.

J Immunother 2014 May;37(4):204-13

*Division of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center ‡Department of Biostatistics, The University of Texas MD Anderson Cancer Center †The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX.

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http://dx.doi.org/10.1097/CJI.0000000000000032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139067PMC
May 2014

Driving CAR-based T-cell therapy to success.

Curr Hematol Malig Rep 2014 Mar;9(1):50-6

Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Pediatrics (Unit #907), 1515 Holcombe Blvd., Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s11899-013-0197-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995024PMC
March 2014

Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents.

Sci Rep 2014 Mar 28;4:4502. Epub 2014 Mar 28.

1] Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 [2] Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.

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http://dx.doi.org/10.1038/srep04502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968458PMC
March 2014

A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19.

Immunol Rev 2014 Jan;257(1):181-90

Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1111/imr.12137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109051PMC
January 2014

Peripheral and thymic foxp3(+) regulatory T cells in search of origin, distinction, and function.

Front Immunol 2013 27;4:253. Epub 2013 Aug 27.

Department of Paediatrics, University Children's Medical Institute, National University Hospital , Singapore.

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http://dx.doi.org/10.3389/fimmu.2013.00253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753660PMC
August 2013

Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy.

Transl Res 2013 Apr 10;161(4):265-83. Epub 2013 Jan 10.

Department of Genetics Cell Biology and Development, Center for Genome Engineering and Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.trsl.2012.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602164PMC
April 2013

Growth and activation of natural killer cells ex vivo from children with neuroblastoma for adoptive cell therapy.

Clin Cancer Res 2013 Apr 1;19(8):2132-43. Epub 2013 Feb 1.

Division of Hematology/Oncology and Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658308PMC
April 2013

Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy.

Stem Cells Transl Med 2013 Apr 20;2(4):274-83. Epub 2013 Mar 20.

Department of Medicine Hematology, Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.5966/sctm.2012-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659832PMC
April 2013

CARs in chronic lymphocytic leukemia -- ready to drive.

Curr Hematol Malig Rep 2013 Mar;8(1):60-70

Department of Stem Cell Transplantation, University of Texas MD Anderson Cancer Center, Unit 423, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s11899-012-0145-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864912PMC
March 2013

Quantitative high-throughput single-cell cytotoxicity assay for T cells.

J Vis Exp 2013 Feb 2(72):e50058. Epub 2013 Feb 2.

Department of Chemical and Biomolecular Engineering, University of Houston, TX, USA.

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http://dx.doi.org/10.3791/50058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596999PMC
February 2013

Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64.

Integr Biol (Camb) 2013 Jan;5(1):231-8

Baylor College of Medicine & Texas Children's Hospital, Department of Obstetrics & Gynecology, Division of Maternal Fetal Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1039/c2ib20093gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713485PMC
January 2013

A new approach to simultaneously quantify both TCR α- and β-chain diversity after adoptive immunotherapy.

Clin Cancer Res 2012 Sep 3;18(17):4733-42. Epub 2012 Jul 3.

Department of Melanoma Medical Oncology, Unit 904, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-3234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823368PMC
September 2012

Good T cells for bad B cells.

Blood 2012 Mar;119(12):2700-2

The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, TX, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-12-39
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http://dx.doi.org/10.1182/blood-2011-12-398719DOI Listing
March 2012

Chimeric antibody receptors (CARs): driving T-cell specificity to enhance anti-tumor immunity.

Front Biosci (Schol Ed) 2012 Jan 1;4:520-31. Epub 2012 Jan 1.

Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889487PMC
January 2012

Efficacy and safety of Sleeping Beauty transposon-mediated gene transfer in preclinical animal studies.

Curr Gene Ther 2011 Oct;11(5):341-9

Dept. of Genetics, Cell Biology and Development, 321 Church St. SE, Minneapolis, MN 55455, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728161PMC
October 2011

Highlights of the second international conference on "Immunotherapy in Pediatric Oncology".

Pediatr Hematol Oncol 2011 Sep;28(6):459-60

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.3109/08880018.2011.596615DOI Listing
September 2011

Off-the-shelf T-cell therapy.

Blood 2010 Dec;116(23):4741-3

University of Texas MD Anderson Cancer Center, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-10-30
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http://dx.doi.org/10.1182/blood-2010-10-308379DOI Listing
December 2010

A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells.

Biomed Microdevices 2010 Oct;12(5):855-63

Division of Pediatrics, Children's Cancer Hospital, The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s10544-010-9440-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109048PMC
October 2010

Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor.

Blood 2010 Aug 3;116(7):1035-44. Epub 2010 May 3.

Division of Pediatrics, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1182/blood-2010-01-043737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938125PMC
August 2010

A transposon and transposase system for human application.

Mol Ther 2010 Apr 26;18(4):674-83. Epub 2010 Jan 26.

Department of Genetics, Cell Biology, and Development, Center for Genome Engineering, Institute of Human Genetics, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152500161632323
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http://dx.doi.org/10.1038/mt.2010.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862530PMC
April 2010

New approaches to allogeneic hematopoietic stem cell transplantation in pediatric cancers.

Curr Oncol Rep 2009 Nov;11(6):423-30

Department of Pediatrics, Unit 907, Children's Cancer Hospital, The University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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November 2009

Persuading natural killer cells to eliminate bad B cells.

Clin Cancer Res 2009 Aug 28;15(15):4790-1. Epub 2009 Jul 28.

Division of Pediatrics, Children's Cancer Hospital, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730884PMC
August 2009

Highlights of the First International "Immunotherapy in Pediatric Oncology: Progress and Challenges" Meeting.

J Pediatr Hematol Oncol 2009 Apr;31(4):227-44

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/MPH.0b013e31819a5d8dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714285PMC
April 2009

Test-driving CARs.

Blood 2008 Sep;112(6):2172-3

University of Texas M.D. Anderson Cancer Center, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-06-16
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http://dx.doi.org/10.1182/blood-2008-06-163006DOI Listing
September 2008

Immunotherapy for pediatric cancer.

Biol Blood Marrow Transplant 2008 Jan;14(1 Suppl 1):33-43

Division of Oncology, Department of Pediatrics, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S108387910700544
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http://dx.doi.org/10.1016/j.bbmt.2007.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888484PMC
January 2008

Antigen-independent and antigen-dependent methods to numerically expand CD19-specific CD8+ T cells.

Exp Hematol 2007 Jul;35(7):1083-90

Division of Molecular Medicine, Beckman Research Institute and City of Hope National Medical Center, Duarte, Calif., USA.

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http://dx.doi.org/10.1016/j.exphem.2007.04.007DOI Listing
July 2007

Lymphoid reconstruction and vaccines.

Biol Blood Marrow Transplant 2007 Jan;13(1 Suppl 1):17-22

Experimental Transplantation and Immunology Branch, National Cancer Institute, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.bbmt.2006.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858644PMC
January 2007

Enhancing siRNA effects in T cells for adoptive immunotherapy.

Hematology 2005 Dec;10(6):461-7

Division of Molecular Biology, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA 90010-3000, USA.

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http://dx.doi.org/10.1080/10245330500233569DOI Listing
December 2005