Laurence G Rahme

Laurence G Rahme

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Laurence G Rahme

Publications by authors named "Laurence G Rahme"

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Pseudomonas aeruginosa Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System.

MBio 2019 Oct 1;10(5). Epub 2019 Oct 1.

Department of Surgery, Center for Surgery, Innovation and Bioengineering, Massachusetts General Hospital, Harvard Medical School Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/mBio.02211-19DOI Listing
October 2019

Targeting bacterial quorum sensing shows promise in improving intestinal barrier function following burn‑site infection.

Mol Med Rep 2019 May 21;19(5):4057-4066. Epub 2019 Mar 21.

Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.3892/mmr.2019.10071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472113PMC
May 2019

Magnetization transfer contrast MRI in GFP‑tagged live bacteria.

Mol Med Rep 2019 Jan 19;19(1):617-621. Epub 2018 Nov 19.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriners Burns Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.3892/mmr.2018.9669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297796PMC
January 2019

Effects of a small, volatile bacterial molecule on Pseudomonas aeruginosa bacteria using whole cell high-resolution magic angle spinning nuclear magnetic resonance spectroscopy and genomics.

Int J Mol Med 2018 Oct 6;42(4):2129-2136. Epub 2018 Jul 6.

NMR Surgical Laboratory, Center for Surgery, Innovation and Bioengineering, Department of Surgery, Massachusetts General and Shriners Burns Hospitals, Harvard Medical School, Boston, MA 02114, USA.

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http://www.spandidos-publications.com/10.3892/ijmm.2018.3760
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http://dx.doi.org/10.3892/ijmm.2018.3760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108874PMC
October 2018

Animal Models for Pseudomonas aeruginosa Quorum Sensing Studies.

Methods Mol Biol 2018 ;1673:227-241

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7309-5_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538071PMC
June 2018

Pharmacological Inhibition of the Pseudomonas aeruginosa MvfR Quorum-Sensing System Interferes with Biofilm Formation and Potentiates Antibiotic-Mediated Biofilm Disruption.

Antimicrob Agents Chemother 2017 12 22;61(12). Epub 2017 Nov 22.

Departments of Surgery and Microbiology and Immunobiology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA, and Shriners Hospitals for Children Boston, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/AAC.01362-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700327PMC
December 2017

Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa.

ACS Chem Biol 2016 11 22;11(11):3061-3067. Epub 2016 Sep 22.

Chemical Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 422, New York, New York 10065, United States

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http://pubs.acs.org/doi/10.1021/acschembio.6b00575
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http://dx.doi.org/10.1021/acschembio.6b00575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117135PMC
November 2016

A quorum-sensing signal promotes host tolerance training through HDAC1-mediated epigenetic reprogramming.

Nat Microbiol 2016 Oct 3;1:16174. Epub 2016 Oct 3.

Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://www.nature.com/articles/nmicrobiol2016174
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066596PMC
http://dx.doi.org/10.1038/nmicrobiol.2016.174DOI Listing
October 2016

Considerations and caveats in anti-virulence drug development.

Curr Opin Microbiol 2016 10 16;33:41-46. Epub 2016 Jun 16.

Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Shriners Hospitals for Children Boston, Boston, MA 02114, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069136PMC
http://dx.doi.org/10.1016/j.mib.2016.06.001DOI Listing
October 2016

TNF-α/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections.

Front Public Health 2016 5;4:216. Epub 2016 Oct 5.

Department of Surgery, Massachusetts General Hospital, Boston, MA, USA; Department of Microbiology and Immunology, Harvard Medical School, Boston, MA, USA; Shriners Hospitals for Children-Boston®, Boston, MA, USA.

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http://dx.doi.org/10.3389/fpubh.2016.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050217PMC
October 2016

Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR.

Sci Rep 2016 Sep 28;6:34083. Epub 2016 Sep 28.

Department of Surgery, Massachusetts General Hospital, Boston MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039717PMC
http://dx.doi.org/10.1038/srep34083DOI Listing
September 2016

Bacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle.

Int J Mol Med 2016 Apr 12;37(4):867-78. Epub 2016 Feb 12.

NMR Surgical Laboratory, Center for Surgery, Innovation and Bioengineering, Department of Surgery, Massachusetts General and Shriners Burns Hospitals, Harvard Medical School, Boston, MA 02114, USA.

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https://www.spandidos-publications.com/10.3892/ijmm.2016.248
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http://dx.doi.org/10.3892/ijmm.2016.2487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790710PMC
April 2016

Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance.

Curr Biol 2016 Jan 14;26(2):195-206. Epub 2016 Jan 14.

Department of Surgery and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Surgery, Center for Surgery, Innovation and Bioengineering, Massachusetts General Hospital, Boston, MA 02114, USA; Shriners Hospitals for Children Boston, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.11.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729643PMC
January 2016

Do standard burn mortality formulae work on a population of severely burned children and adults?

Burns 2015 Aug 25;41(5):935-45. Epub 2015 Apr 25.

Department of Surgery, Massachusetts General Hospital, Bigelow 1302, 55 Fruit Street, Boston, MA 02114, USA; Shriners Hospitals for Children-Boston®, 51 Blossom St., Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2015.03.017DOI Listing
August 2015

Prediction of multiple infections after severe burn trauma: a prospective cohort study.

Ann Surg 2015 Apr;261(4):781-92

*Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA †Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA ‡Shriners Hospitals for Children Boston, Boston, MA §Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland ¶Department of Biochemistry and Stanford Genome Technology Center, Stanford University School of Medicine, Palo Alto, CA ‖Department of Biomedical Engineering, Worcester Polytechnic Institute, Worchester, MA **Program in Bioinformatics and Computational Biology, Worcester Polytechnic Institute, Worchester, MA.

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http://dx.doi.org/10.1097/SLA.0000000000000759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284150PMC
April 2015

Assessing Pseudomonas virulence with the nonmammalian host model: Arabidopsis thaliana.

Methods Mol Biol 2014 ;1149:689-97

Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1007/978-1-4939-0473-0_53DOI Listing
March 2015

Assessing Pseudomonas aeruginosa Persister/antibiotic tolerant cells.

Methods Mol Biol 2014 ;1149:699-707

Department of Surgery, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-0473-0_54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538066PMC
March 2015

A quorum sensing small volatile molecule promotes antibiotic tolerance in bacteria.

PLoS One 2013 19;8(12):e80140. Epub 2013 Dec 19.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America ; Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080140PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868577PMC
October 2014

In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in Drosophila GST2 mutants.

Int J Mol Med 2014 Jul 24;34(1):327-33. Epub 2014 Apr 24.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriners Burn Institute, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.3892/ijmm.2014.1757DOI Listing
July 2014

A small volatile bacterial molecule triggers mitochondrial dysfunction in murine skeletal muscle.

PLoS One 2013 30;8(9):e74528. Epub 2013 Sep 30.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Athinoula A. Martinos Center of Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Shriners Hospitals for Children Boston, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074528PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787027PMC
May 2014

Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model.

Int J Oncol 2013 Sep 28;43(3):886-94. Epub 2013 Jun 28.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriners Burn Institute, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.3892/ijo.2013.1998DOI Listing
September 2013

Live-cell high resolution magic angle spinning magnetic resonance spectroscopy for analysis of metabolomics.

Biomed Rep 2013 Sep 22;1(5):707-712. Epub 2013 Jul 22.

Nuclear Magnetic Resonance Surgical Laboratory, Department of Surgery, Division of Burns, Massachusetts General Hospital and Shriners Burns Institute, Harvard Medical School, Boston, MA 02114, USA ; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.3892/br.2013.148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917020PMC
September 2013

Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy.

FASEB J 2013 Jun 12;27(6):2521-30. Epub 2013 Mar 12.

Nuclear Magnetic Resonance Surgical Laboratory, Department of Surgery, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Shriners Burns Institute, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1096/fj.12-220764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659352PMC
June 2013

The quorum sensing volatile molecule 2-amino acetophenon modulates host immune responses in a manner that promotes life with unwanted guests.

PLoS Pathog 2012 15;8(11):e1003024. Epub 2012 Nov 15.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499575PMC
April 2013

Production of Pseudomonas aeruginosa Intercellular Small Signaling Molecules in Human Burn Wounds.

J Pathog 2011 17;2011:549302. Epub 2011 Mar 17.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA ; Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4061/2011/549302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594954PMC
March 2013

A method for high throughput determination of viable bacteria cell counts in 96-well plates.

BMC Microbiol 2012 Nov 13;12:259. Epub 2012 Nov 13.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1186/1471-2180-12-259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534621PMC
November 2012

Honey's Ability to Counter Bacterial Infections Arises from Both Bactericidal Compounds and QS Inhibition.

Front Microbiol 2012 11;3:144. Epub 2012 Apr 11.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital Boston, MA, USA.

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http://dx.doi.org/10.3389/fmicb.2012.00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323871PMC
October 2012

Imaging C-Fos Gene Expression in Burns Using Lipid Coated Spion Nanoparticles.

Adv J Mol Imaging 2012 Oct;2(4):31-37

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriners Burns Institute, Harvard Medical School, Boston, USA ; Athinoula A. Martinos Center of Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, USA ; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.4236/ami.2012.24005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076698PMC
October 2012

Immune response to bacteria induces dissemination of Ras-activated Drosophila hindgut cells.

EMBO Rep 2012 Jun 1;13(6):569-76. Epub 2012 Jun 1.

Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/embor.2012.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367237PMC
June 2012

Drosophila melanogaster as a model for human intestinal infection and pathology.

Dis Model Mech 2011 Jan;4(1):21-30

Department of Surgery, Massachusetts General Hospital, 50 Blossom Street, Their 340, Boston, MA 02114, USA.

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http://dx.doi.org/10.1242/dmm.003970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014343PMC
January 2011

Magnetic resonance spectroscopy of live Drosophila melanogaster using magic angle spinning.

J Vis Exp 2010 Apr 15(38). Epub 2010 Apr 15.

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, MA, USA.

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http://dx.doi.org/10.3791/1710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278327PMC
April 2010

Homeostatic interplay between bacterial cell-cell signaling and iron in virulence.

PLoS Pathog 2010 Mar 12;6(3):e1000810. Epub 2010 Mar 12.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837411PMC
March 2010

Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection.

Nat Protoc 2009 13;4(9):1285-94. Epub 2009 Aug 13.

Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nprot.2009.124DOI Listing
October 2009

Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.

Int J Mol Med 2009 Sep;24(3):387-92

NMR Surgical Laboratory, Department of Surgery, Massachusetts General and Shriners Hospitals, Harvard Medical School, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207251PMC
http://dx.doi.org/10.3892/ijmm_00000244DOI Listing
September 2009

The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria.

PLoS One 2009 Sep 25;4(9):e7167. Epub 2009 Sep 25.

Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007167PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744870PMC
September 2009

Modeling Pseudomonas aeruginosa pathogenesis in plant hosts.

Nat Protoc 2009 ;4(2):117-24

Department of Surgery at Massachusetts General Hospital, 50 Blossom St., Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/nprot.2008.224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501584PMC
April 2009

Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma.

Int J Mol Med 2008 Jun;21(6):825-32

NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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June 2008

Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosa.

BMC Mol Biol 2008 Feb 4;9:20. Epub 2008 Feb 4.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1186/1471-2199-9-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287187PMC
February 2008

Inhibitors of pathogen intercellular signals as selective anti-infective compounds.

PLoS Pathog 2007 Sep;3(9):1229-39

Department of Surgery, Microbiology and Molecular Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.ppat.0030126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323289PMC
September 2007

Uncoupling protein 3 expression and intramyocellular lipid accumulation by NMR following local burn trauma.

Int J Mol Med 2006 Dec;18(6):1223-9

Department of Surgery, Massachusetts General Hospital, Shriners Burn Institute and Harvard Medical School, Boston, MA 02114, USA.

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December 2006

Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle.

J Trauma 2006 Aug;61(2):280-92

Department of Surgery, Massachusetts General Hospital, Shriners Burns, Institute and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1097/01.ta.0000230567.56797.6cDOI Listing
August 2006

Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry.

Microbiology 2006 Jun;152(Pt 6):1679-86

Department of Surgery, Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1099/mic.0.28605-0DOI Listing
June 2006

Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis.

FASEB J 2005 Sep;19(11):1431-40

Department of Surgery, Massachusetts General Hospital, Shriners Burns Institute and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1096/fj.04-2005comDOI Listing
September 2005

Burn injury causes mitochondrial dysfunction in skeletal muscle.

Proc Natl Acad Sci U S A 2005 Apr 4;102(15):5368-73. Epub 2005 Apr 4.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1073/pnas.0501211102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC556259PMC
April 2005

Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression.

Proc Natl Acad Sci U S A 2005 Feb 4;102(7):2573-8. Epub 2005 Feb 4.

Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1073/pnas.0409588102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549001PMC
February 2005

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response.

Eukaryot Cell 2004 Apr;3(2):413-9

Department of Surgery, Massachusetts General Hospital. Shriner's Burns Institute, Boston, Massachusetts 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC387633PMC
http://dx.doi.org/10.1128/ec.3.2.413-419.2004DOI Listing
April 2004

Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication.

Proc Natl Acad Sci U S A 2004 Feb 22;101(5):1339-44. Epub 2004 Jan 22.

Department of Surgery, Harvard Medical School and Shriners Burns Institute, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1073/pnas.0307694100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC337054PMC
February 2004

Pseudomonas aeruginosa-plant root interactions. Pathogenicity, biofilm formation, and root exudation.

Plant Physiol 2004 Jan 30;134(1):320-31. Epub 2003 Dec 30.

Department of Horticulture and Landscape Architecture, Colorado State University, Fort Collins, Colorado 80523, USA.

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http://dx.doi.org/10.1104/pp.103.027888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC316311PMC
January 2004

Use of plant and insect hosts to model bacterial pathogenesis.

Methods Enzymol 2002 ;358:3-13

Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)58077-0DOI Listing
January 2003