Publications by authors named "Laurence Albiges"

100Publications

Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Nivolumab plus Cabozantinib Joins Immune Checkpoint Inhibition Combination Therapies for Treatment-naïve Metastatic Clear-Cell Renal Cell Carcinoma.

Eur Urol 2020 Dec 20. Epub 2020 Dec 20.

The Royal Free London NHS Foundation Trust, London, UK; UCL Division of Surgery and Interventional Science, University College London, London, UK; Department of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Electronic address:

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December 2020

Immunomodulatory Roles of VEGF Pathway Inhibitors in Renal Cell Carcinoma.

Drugs 2020 Aug;80(12):1169-1181

Department of Medical Oncology, Gustave Roussy, 114 rue Edouard Vaillant, 94800, Villejuif, France.

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August 2020

Management of Metastatic Nonclear Renal Cell Carcinoma: What Are the Options and Challenges?

Eur Urol Oncol 2020 Jun 15. Epub 2020 Jun 15.

Predictive onco-uro, APHP, Urology, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.

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June 2020

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients.

Eur Urol 2020 08 4;78(2):195-206. Epub 2020 May 4.

Gustave Roussy Cancer Campus (GRCC), Villejuif, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U1015, Équipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France; Faculté de Médecine Kremlin-Bicêtre, Université Paris Sud, Université Paris Saclay, France; Department of Medical Oncology, Gustave Roussy Cancer Campus (GRCC), Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France; EverImmune, GRCC, Villejuif, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China. Electronic address:

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August 2020

Tyrosine kinase inhibitors and immunotherapy combinations in renal cell carcinoma.

Ther Adv Med Oncol 2020 18;12:1758835920907504. Epub 2020 Mar 18.

Department of Cancer Medicine, Gustave Roussy Institute, Université Paris-Saclay, 114 rue Edouard Vaillant, Villejuif, 94805, France.

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March 2020

The Effect of Weight Change During Treatment With Targeted Therapy in Patients With Metastatic Renal Cell Carcinoma.

Clin Genitourin Cancer 2019 12 19;17(6):443-450.e1. Epub 2019 Jul 19.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

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December 2019

Renal Cell Carcinoma with bone metastases isn't always bad.

Oncotarget 2019 Jul 16;10(44):4511-4512. Epub 2019 Jul 16.

Department of Cancer Medicine, Gustave Roussy Cancer Campus, Paris-Sud University, Villejuif, France.

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July 2019

Clear-cell Renal Cell Carcinoma: Molecular Characterization of IMDC Risk Groups and Sarcomatoid Tumors.

Clin Genitourin Cancer 2019 10 25;17(5):e981-e994. Epub 2019 May 25.

Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium; Inserm, UMR-1162, Génomique fonctionnelle des tumeurs solides, IUH, Paris, France. Electronic address:

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October 2019

Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Immune Checkpoint Inhibition Is the New Backbone in First-line Treatment of Metastatic Clear-cell Renal Cell Carcinoma.

Eur Urol 2019 Aug;76(2):151-156

Department of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; Specialist Centre for Kidney Cancer, Royal Free London NHS Foundation Trust, London, UK; UCL Division of Surgery and Interventional Science, London, UK. Electronic address:

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August 2019

Body Mass Index and Outcomes in Germ-Cell Tumors.

Clin Genitourin Cancer 2019 08 25;17(4):283-290. Epub 2019 Apr 25.

Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH.

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August 2019

Welcome to European Urology Oncology: Your New Journal, Where Multiple Disciplines Meet To Improve Care of Patients with Genitourinary Cancers.

Eur Urol Oncol 2018 05 15;1(1):1-2. Epub 2018 May 15.

Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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May 2018

[Testicular tumors: A diagnostic challenge of imaging].

Bull Cancer 2019 Oct 12;106(10):875-886. Epub 2019 May 12.

Institut Gustave-Roussy, département d'oncologie, 114, rue Edouard-Vaillaxnt, 94805 Villejuif, France.

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October 2019

Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma.

N Engl J Med 2019 03 16;380(12):1103-1115. Epub 2019 Feb 16.

From Memorial Sloan Kettering Cancer Center (R.J.M.) and Pfizer (S.H.), New York; Private Medical Institution Euromedservice (K.P.) and Nonstate Health Institution Road Clinical Hospital-Russian Railways (A.V.), St. Petersburg, and the Moscow Scientific Research Oncology Institute, Moscow (B.A.) - all in Russia; the Netherlands Cancer Institute, Amsterdam (J.H.); the Cleveland Clinic, Cleveland (B.R.); Institut Gustave Roussy, Villejuif (L.A.), and Centre Léon Bérard, University of Lyon, Lyon (S.N.) - both in France; the University of Texas M.D. Anderson Cancer Center, Houston (M.T.C.); University of Glasgow, Beatson West of Scotland Cancer Centre, Glasgow (B.V.), and Royal Marsden NHS Foundation Trust, London (J.L.) - both in the United Kingdom; British Columbia Cancer Agency, Vancouver (C.K.), and Lady Davis Institute and Jewish General Hospital, McGill University, Montreal (W.H.M.) - both in Canada; Osaka University Hospital, Osaka, Japan (M.U.); University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea (J.L.L.); Macquarie University, Sydney (H.G.); Department of Medicine I, Clinical Division of Oncology and Comprehensive Cancer Center, Medical University of Vienna, Vienna (M.S.); Georgetown Lombardi Comprehensive Cancer Center, Washington, DC (M.B.A.); Department of Urology, University of Tübingen, Tübingen, Germany (J.B.); Pfizer, Cambridge (J.W., A.C.), and the Lank Center for Genitourinary Oncology at Dana-Farber Cancer Institute, and Brigham and Women's Hospital, Boston (T.K.C.) - both in Massachusetts; Pfizer (M.M., A.P.) and Pfizer Italia (C.F.), Milan; Pfizer, San Diego, CA (P.B.R.); and Pfizer, Groton, CT (B.H.).

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March 2019

Cold agglutinin disease as a new immune-related adverse event associated with anti-PD-L1s and its treatment with rituximab.

Eur J Cancer 2019 03 7;110:21-23. Epub 2019 Feb 7.

APHP, Service de Médecine Interne Immunologie Clinique, Hôpitaux Universitaires Paris Sud, Le Kremlin Bicêtre, France. Electronic address:

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March 2019

A new prognostic model for survival in second line for metastatic renal cell carcinoma: development and external validation.

Angiogenesis 2019 08 9;22(3):383-395. Epub 2019 Feb 9.

Departments of Medical Oncology, Gustave Roussy, 114 Rue Edward Vaillant, 94800, Villejuif, France.

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August 2019

Characterization of Testicular Masses in Adults: Performance of Combined Quantitative Shear Wave Elastography and Conventional Ultrasound.

Ultrasound Med Biol 2019 03 29;45(3):720-731. Epub 2018 Dec 29.

Institut Langevin, ESPCI Paris, PSL Research University CNRS UMR 7587, INSERM ERL U-979, Paris, France; Department of Adult Radiology, Necker University Hospital, Paris, France; Paris Descartes University, Paris, France.

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March 2019

Traitement des métastases osseuses du cancer du rein.

Bull Cancer 2018 Dec;105 Suppl 3:S268-S279

Département d'oncologie médicale, Gustave Roussy, Villejuif, France.. Electronic address:

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December 2018

Les métastases cérébrales de cancer du rein, un défi clinique.

Bull Cancer 2018 Dec;105 Suppl 3:S261-S267

Département de médecine oncologique, Gustave-Roussy, Villejuif, France. Electronic address:

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December 2018

Cancer du rein : tendances et perspectives.

Bull Cancer 2018 Dec;105 Suppl 3:S219-S220

Département de radiothérapie, institut de cancérologie Lucien-Neuwirth 108 bis, avenue Albert-Raimond, BP 60008, 42270 Saint-Priest-en-Jarez, cedex, France. Electronic address:

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December 2018

Haematological immune-related adverse events induced by anti-PD-1 or anti-PD-L1 immunotherapy: a descriptive observational study.

Lancet Haematol 2019 Jan 4;6(1):e48-e57. Epub 2018 Dec 4.

Service de Médecine Interne and Immunologie Clinique, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France; Université Paris Sud, Centre de Recherche en Immunologie des Infections Virales et des Maladies Auto-Immunes, INSERM, Le Kremlin-Bicêtre, France; Division d'Immunovirologie, Commissariat à l'Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, France.

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January 2019

Non-Clear Cell Renal Cell Carcinomas: From Shadow to Light.

J Clin Oncol 2018 Oct 29:JCO2018792531. Epub 2018 Oct 29.

Laurence Albiges and Ronan Flippot, Gustave Roussy, Université Paris-Saclay, Villejuif; Nathalie Rioux-Leclercq, Rennes University Hospital, Rennes, France; and Toni K. Choueiri, Dana-Farber Cancer Institute, Boston, MA.

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October 2018

Systemic Treatment of Metastatic Clear Cell Renal Cell Carcinoma in 2018: Current Paradigms, Use of Immunotherapy, and Future Directions.

Eur Urol 2019 01 13;75(1):100-110. Epub 2018 Oct 13.

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Electronic address:

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January 2019

Immune Checkpoint Inhibitors: Toward New Paradigms in Renal Cell Carcinoma.

Drugs 2018 Sep;78(14):1443-1457

Department of Medical Oncology, Gustave Roussy, 114 rue Edouard Vaillant, 94800, Villejuif, France.

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September 2018

Treating patients with renal cell carcinoma and bone metastases.

Expert Rev Anticancer Ther 2018 11 13;18(11):1135-1143. Epub 2018 Sep 13.

a Department of Medical Oncology , Gustave Roussy , Villejuif , France.

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November 2018

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma.

N Engl J Med 2018 Aug 3;379(5):417-427. Epub 2018 Jun 3.

From the Departments of Urology (A.M., M.-O.T.) and Medical Oncology (S.O.), Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Descartes, and Paris Descartes Necker-Cochin Clinical Research Unit, AP-HP (S.C.), Paris, the Department of Medical Oncology, Bordeaux University Hospital (A.R.), the Department of Medical Oncology, Hôpital Saint André, Centre Hospitalier Universitaire (CHU) de Bordeaux (M.G.-G.), and the Department of Urology, CHU de Bordeaux and Université de Bordeaux (J.-C.B.), Bordeaux, Biometrics Unit, Cancer Institute of Montpellier, University of Montpellier, Montpellier (S.T.), the Department of Urology, CHU Rangueil (J.-B.B.), and the Department of Medical Oncology, Institut Universitaire du Cancer Toulouse-Oncopole (C.C.), Toulouse, the Department of Urology, University of Rennes (K.B.), and the Department of Medical Oncology, Centre Eugene Marquis (B.L.), Rennes, the Department of Medical Oncology, Institut de Cancerologie de Lorraine, Vandoeuvre lès Nancy (L. Geoffrois), the Department of Medical Oncology, CHU Besançon, Oncologie, and Université de Franche-Comte, INSERM Unité Mixte de Recherche (UMR) 1098, Structure Fédérative de Recherche Ingénierie et Biologie Cellulaire et Tissulaire, Besançon (A.T.-V.), the Department of Urology, CHU François Mitterrand, Dijon (L.C.), the Department of Urology, CHU Strasbourg, Translational Medicine Federation Strasbourg, Strasbourg (H.L.), the Department of Urology, Gabriel Montpied Hospital, and Clermont Auvergne University, Clermont-Ferrand (L. Guy), the Department of Medical Oncology, Centre de Recherche en Cancerologie de Marseille, INSERM UMR 1068, Centre National de la Recherche Scientifique UMR 7258 and Institut Paoli-Calmettes (G.G.), and the Department of Urology, Hôpital la Conception (E.L.), Aix Marseille Université, Marseille, the Department of Medical Oncology, Institut de Cancerologie de l'Ouest, Nantes (F.R.), the Department of Medical Oncology, CHU Bretonneau, and the Department of Medicine, Université François Rabelais, Tours (C.L.), the Department of Urology, Mont de Marsan General Hospital, Mont de Marsan (J.-J.P.), the Departments of Medical Oncology (C.T.) and Urology (T.L.), Hôpital Foch, Suresnes, the Department of Urology, Imagerie Adaptative Diagnostique et Interventionnelle INSERM Unité 1254, CHU de Nancy, Brabois (J.H.), the Department of Medical Oncology, Institut Gustave Roussy and Université Paris-Saclay, Villejuif (L.A., B.E.), and Université Versailles, St.-Quentin-en-Yvelines (T.L.) - all in France; the Department of Urology, Haukeland University Hospital (C.B.), and the Department of Clinical Medicine, University of Bergen (C.B.), Bergen, Norway; and the Department of Urology, Royal Free Hospital, London (M.A.).

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August 2018

Safety and efficacy of anti-programmed death 1 antibodies in patients with cancer and pre-existing autoimmune or inflammatory disease.

Eur J Cancer 2018 03 10;91:21-29. Epub 2018 Jan 10.

Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Service de Médecine Interne et Immunologie Clinique, F-94275, Le Kremlin-Bicêtre, France; INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases, F-94276, Le Kremlin-Bicêtre, France; Université Paris Sud, UMR 1184, F-94276, Le Kremlin-Bicêtre, France; CEA, DSV/iMETI, IDMIT, F-92265, Fontenay-aux-Roses, France. Electronic address:

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March 2018

ERCC1 as a prognostic factor for survival in patients with advanced urothelial cancer treated with platinum based chemotherapy: A systematic review and meta-analysis.

Crit Rev Oncol Hematol 2017 Dec 2;120:120-126. Epub 2017 Nov 2.

Bladder Cancer Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address:

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December 2017

Smoking and Disease Outcomes in Patients With Malignant Germ Cell Tumors.

Clin Genitourin Cancer 2017 Aug 3. Epub 2017 Aug 3.

Dana-Farber Cancer Institute, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:

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August 2017

Age ≥40 Years Is Associated with Adverse Outcome in Metastatic Germ Cell Cancer Despite Appropriate Intended Chemotherapy.

Eur Urol Focus 2017 12 26;3(6):621-628. Epub 2016 Oct 26.

Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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December 2017

Recommendations for the Management of Rare Kidney Cancers.

Eur Urol 2017 12 16;72(6):974-983. Epub 2017 Jul 16.

Division of Surgical Oncology, Department of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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December 2017

Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.

J Clin Oncol 2017 Sep 23;35(26):2993-3001. Epub 2017 Jun 23.

Toni K. Choueiri, Dana-Farber Cancer Institute, Boston; Melanie M. Frigault, Edwin A. Clark, Amir A. Handzel, and Humphrey Gardner, AstraZeneca, Waltham, MA; Elizabeth Plimack, Fox Chase Cancer Center, Philadelphia, PA; Eric Jonasch, MD Anderson Cancer Center, Houston, TX; Sumanta Kumar Pal, City of Hope, Duarte, CA; Hendrik-Tobias Arkenau, Sarah Cannon Research Institute, University College London Cancer Institute; Thomas Powles, Barts Cancer Institute, London; Shethah Morgan, AstraZeneca, Cambridge, United Kingdom; Daniel Y.C. Heng, Tom Baker Cancer Center, Calgary, Alberta, Canada; and Laurence Albiges, Institute Gustave Roussy, Paris, France.

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September 2017

Testicular ultrasensitive Doppler preliminary experience: a feasibility study.

Acta Radiol 2018 Mar 1;59(3):346-354. Epub 2017 Jun 1.

3 Institut Langevin, ESPCI Paris, PSL Research University CNRS UMR 7587, INSERM U979, Paris, France.

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March 2018

Long-term complete remission with Ipilimumab in metastatic castrate-resistant prostate cancer: case report of two patients.

J Immunother Cancer 2017 18;5:31. Epub 2017 Apr 18.

Institut Gustave Roussy, University of Paris-Sud, Department of Cancer Medicine, 114 Rue Edouard Vaillant, 94800 Villejuif, France.

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June 2018

Antiangiogenic therapy combined with immune checkpoint blockade in renal cancer.

Angiogenesis 2017 May 11;20(2):205-215. Epub 2017 Apr 11.

Department of Urology, The Netherlands Cancer Institute, Postbus 90203, 1006 BE, Amsterdam, The Netherlands.

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May 2017

Nivolumab in renal cell carcinoma: latest evidence and clinical potential.

Ther Adv Med Oncol 2017 Mar 11;9(3):171-181. Epub 2016 Dec 11.

Département de médecine Oncologique, Gustave Roussy, Université Paris-Saclay, Villejuif, F-94805, 114 Rue Edouard Vaillant, 94800 Villejuif, France.

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March 2017

Renal cell carcinoma.

Nat Rev Dis Primers 2017 Mar 9;3:17009. Epub 2017 Mar 9.

Department of Experimental and Clinical Medical Sciences - Urologic Clinic, University of Udine, Udine, Italy.

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March 2017

Onset of connective tissue disease following anti-PD1/PD-L1 cancer immunotherapy.

Ann Rheum Dis 2018 03 27;77(3):468-470. Epub 2017 Feb 27.

Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Service de Médecine Interne et Immunologie clinique, Le Kremlin-Bicêtre, France.

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March 2018

Renal-cell carcinoma in 2016: Advances in treatment - jostling for pole position.

Nat Rev Clin Oncol 2017 Feb 10;14(2):82-84. Epub 2017 Jan 10.

Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Dana 1230, Boston, Massachusetts 02215, USA.

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February 2017

Hypertension and Angiotensin System Inhibitors in Patients with Metastatic Renal Cell Carcinoma.

Oncol Rev 2016 Oct 24;10(2):298. Epub 2016 Nov 24.

Gustave Roussy Cancer Center, University of Paris-Saclay , Villejuif, France.

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October 2016

Cabozantinib for the treatment of renal cell carcinoma.

Expert Opin Pharmacother 2016 Dec 22;17(18):2499-2504. Epub 2016 Nov 22.

a Department of Medical Oncology , Gustave Roussy , Villejuif , France.

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December 2016

Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations.

J Clin Oncol 2016 Oct;34(30):3655-3663

Laurence Albiges, Wanling Xie, Rana R. McKay, Andre P. Fay, Guillermo de Velasco, Sabina Signoretti, and Toni K. Choueiri, Dana-Farber Cancer Institute; Wanling Xie, Rana R. McKay, Mark A. Preston, Eunyoung Cho, Sabina Signoretti, and Toni K. Choueiri, Brigham and Women's Hospital; Laurence Albiges, Wanling Xie, Rana R. McKay, Andre P. Fay, Guillermo de Velasco, Eunyoung Cho, David F. McDermott, Sabina Signoretti, and Toni K. Choueiri, Harvard Medical School; Mark A. Preston and Kathryn M. Wilson, Harvard School of Public Health; David F. McDermott, Beth Israel Deaconess Medical Center, Boston, MA; Laurence Albiges, Gustave Roussy, Université Paris-Saclay, Villejuif, France; A. Ari Hakimi, Emily C. Zabor, Anders J. Skanderup, and Helena Furberg, Memorial Sloan Kettering Cancer Center, New York; Ronit Simantov and Xun Lin, Pfizer Oncology, New York, NY; Jae-Lyun Lee, University of Ulsan College of Medicine, Asan; Sun-Young Rha, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea; Brian I. Rini, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH; Sandy Srinivas, Stanford Cancer Institute, Stanford; Sumanta K. Pal, City of Hope Comprehensive Cancer Center, Duarte, CA; Georg A. Bjarnason, Sunnybrook Odette Cancer Center, Toronto; Scott Ernst, London Health Sciences Center, London, Ontario; Lori A. Wood, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia; Daniel Y.C. Heng, Tom Baker Cancer Center; University of Calgary, Calgary, Alberta, Canada; Ulka N. Vaishamayan, Karmanos Cancer Center, Detroit, MI; Neeraj Agarwal, University of Utah Huntsman Cancer Institute, Salt Lake City, UT; Takeshi Yuasa, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan; Aristotelis Bamias, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece; and Eunyoung Cho, The Warren Alpert Medical School of Brown University; Brown University School of Public Health, Providence, RI.

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October 2016

Assessment of Early Tumour Shrinkage: Ready for Integration in the Treatment Strategy for Metastatic Renal Cell Carcinoma?

Eur Urol 2016 12 5;70(6):1016-1018. Epub 2016 Aug 5.

Genitourinary Oncology, Department of Medicine, Gustave Roussy Université Paris-Saclay, Villejuif, France.

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December 2016