Publications by authors named "Lauren Averett Byers"

40Publications

This Is Our Cells Under Pressure: Decreased DNA Damage Repair in Response to Targeted Therapies Facilitates the Emergence of Drug-Resistant Clones.

Cancer Cell 2020 01;37(1):5-7

Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.12.005DOI Listing
January 2020

Temozolomide plus PARP Inhibition in Small-Cell Lung Cancer: Could Patient-Derived Xenografts Accelerate Discovery of Biomarker Candidates?

Cancer Discov 2019 Oct;9(10):1340-1342

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0850DOI Listing
October 2019

Integrated Approaches for the Use of Large Datasets to Identify Rational Therapies for the Treatment of Lung Cancers.

Cancers (Basel) 2019 Feb 19;11(2). Epub 2019 Feb 19.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers11020239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406670PMC
February 2019

Evading the STING: LKB1 Loss Leads to STING Silencing and Immune Escape in KRAS-Mutant Lung Cancers.

Cancer Discov 2019 01;9(1):16-18

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-18-1286DOI Listing
January 2019

ILK and SHP2 expression identify a poor prognostic cohort of EGFR-mutant lung cancer.

EBioMedicine 2019 01 13;39:5-6. Epub 2018 Dec 13.

Medical Oncology, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1016/j.ebiom.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355652PMC
January 2019

Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.

J Clin Oncol 2018 08 15;36(23):2386-2394. Epub 2018 Jun 15.

M. Catherine Pietanza, Lee M. Krug, Mark G. Kris, and Charles M. Rudin, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College; Kaitlin M. Woo, Yevgeniva Bensman, Brenda Hurtado, and Martin Fleisher, Memorial Sloan Kettering Cancer Center, New York, NY; Saiama N. Waqar, Washington University School of Medicine in St. Louis, St Louis, MO; Afshin Dowlati, Case Western Reserve University and University Hospitals Seidman Cancer Center, Cleveland, OH; Christine L. Hann, Johns Hopkins University, Baltimore; Alice Chen, National Institutes of Health, Bethesda, MD; Alberto Chiappori, H. Lee Moffitt Cancer Center, Tampa, FL; Taofeek K. Owonikoko, Emory University, Atlanta, GA; and Robert J. Cardnell, Junya Fujimoto, Lihong Long, Lixia Diao, Jing Wang, Patricia de Groot, Erik P. Sulman, Ignacio I. Wistuba, John V. Heymach, and Lauren Averett Byers, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2018.77.7672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085179PMC
August 2018

Targeting DNA damage repair in small cell lung cancer and the biomarker landscape.

Transl Lung Cancer Res 2018 Feb;7(1):50-68

Department of Thoracic and Head & Neck Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.21037/tlcr.2018.02.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835589PMC
February 2018

Targeting AXL and mTOR Pathway Overcomes Primary and Acquired Resistance to WEE1 Inhibition in Small-Cell Lung Cancer.

Clin Cancer Res 2017 Oct 11;23(20):6239-6253. Epub 2017 Jul 11.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882197PMC
October 2017

Giving AXL the axe: targeting AXL in human malignancy.

Br J Cancer 2017 Feb 10;116(4):415-423. Epub 2017 Jan 10.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://www.nature.com/articles/bjc2016428
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http://dx.doi.org/10.1038/bjc.2016.428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318970PMC
February 2017

AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers.

Mol Cancer Res 2017 01 26;15(1):45-58. Epub 2016 Sep 26.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, 6565 MD Anderson Blvd. Unit 1052, Houston, Texas 77030.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215967PMC
January 2017

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 Oct;34(30):3638-3647

Vassiliki Papadimitrakopoulou, J. Jack Lee, Ignacio I. Wistuba, Anne S. Tsao, Frank V. Fossella, Neda Kalhor, Sanjay Gupta, Lauren Averett Byers, Julie G. Izzo, Ximing Tang, Ferdinandos Skoulidis, Don L. Gibbons, Li Shen, Caimiao Wei, Lixia Diao, S. Andrew Peng, Jing Wang, Alda L. Tam, John V. Heymach, and Waun Ki Hong, The University of Texas MD Anderson Cancer Center, Houston, TX; Scott N. Gettinger, Sarah B. Goldberg, Ja Seok Koo, and Roy S. Herbst, Yale University, New Haven, CT; Vincent A. Miller, Foundation Medicine, Cambridge, MA; Kevin R. Coombes, Ohio State University College of Medicine, Columbus, OH; and David J. Mauro and Eric H. Rubin, Merck, North Wales, PA.

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http://dx.doi.org/10.1200/JCO.2015.66.0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065110PMC
October 2016

Selecting Reliable mRNA Expression Measurements Across Platforms Improves Downstream Analysis.

Cancer Inform 2016 10;15:81-9. Epub 2016 May 10.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.4137/CIN.S38590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863871PMC
May 2016

Axl Receptor Axis: A New Therapeutic Target in Lung Cancer.

J Thorac Oncol 2016 08 26;11(8):1357-1362. Epub 2016 Apr 26.

Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961571PMC
August 2016

Altering the Course of Small Cell Lung Cancer: Targeting Cancer Stem Cells via LSD1 Inhibition.

Cancer Cell 2015 Jul;28(1):4-6

Department of Thoracic and Head and Neck Medical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497474PMC
July 2015

Small cell lung cancer: will recent progress lead to improved outcomes?

Clin Cancer Res 2015 May;21(10):2244-55

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497796PMC
May 2015

Small cell lung cancer: where do we go from here?

Cancer 2015 Mar 21;121(5):664-72. Epub 2014 Oct 21.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncr.29098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497465PMC
March 2015

A HER 1-2 punch: dual EGFR targeting deals resistance a deadly blow.

Cancer Discov 2014 Sep;4(9):991-4

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990388PMC
September 2014

Identification and characterization of a suite of tumor targeting peptides for non-small cell lung cancer.

Sci Rep 2014 Mar 27;4:4480. Epub 2014 Mar 27.

1] Departments of Internal Medicine, University of Texas Southwestern Medical Center 5323 Harry Hines Blvd. Dallas, TX 75390-8807, USA [2] The Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center 5323 Harry Hines Blvd. Dallas, TX 75390-8807, USA.

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http://dx.doi.org/10.1038/srep04480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967199PMC
March 2014

Teaching an old dog new tricks: drug repositioning in small cell lung cancer.

Cancer Discov 2013 Dec;3(12):1333-5

1Departments of Bioinformatics and Computational Biology and 2Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878064PMC
December 2013

Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.

Clin Cancer Res 2009 Nov 27;15(22):6852-61. Epub 2009 Oct 27.

Division of Cancer Medicine and Department of Thoracic/Head and Neck Medical Oncology, Unit 432, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030-4009, USA.

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http://clincancerres.aacrjournals.org/content/clincanres/ear
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-09-0767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935176PMC
November 2009