Publications by authors named "Lauren A Byers"

69Publications

Metastatic lung adenocarcinoma mimicking Richter transformation in a patient with chronic lymphocytic leukemia.

Leuk Res 2020 Sep 13;98:106445. Epub 2020 Sep 13.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2020.106445DOI Listing
September 2020

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8 T cell exhaustion.

Nat Commun 2020 09 9;11(1):4520. Epub 2020 Sep 9.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-020-18298-8DOI Listing
September 2020

Comparative genomics of high grade neuroendocrine carcinoma of the cervix.

PLoS One 2020 16;15(6):e0234505. Epub 2020 Jun 16.

Department of Gynecologic Oncology & Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234505PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297329PMC
August 2020

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.

Mol Cell 2019 12 26;76(5):838-851.e5. Epub 2019 Sep 26.

Children's Medical Center Research Institute at UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.08.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898782PMC
December 2019

PARP Inhibition Combined with Immune Checkpoint Blockade in SCLC: Oasis in an Immune Desert or Mirage?

J Thorac Oncol 2019 08;14(8):1323-1326

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193036
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http://dx.doi.org/10.1016/j.jtho.2019.05.004DOI Listing
August 2019

PARP Inhibitors: Extending Benefit Beyond -Mutant Cancers.

Clin Cancer Res 2019 07 13;25(13):3759-3771. Epub 2019 Feb 13.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-0968DOI Listing
July 2019

Beyond chemotherapy: Emerging biomarkers and therapies as small cell lung cancer enters the immune checkpoint era.

Cancer 2019 02 8;125(4):496-498. Epub 2019 Jan 8.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncr.31863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353664PMC
February 2019

Reply to F. Liang.

J Clin Oncol 2019 01 29;37(3):259. Epub 2018 Nov 29.

M. Catherine Pietanza, MD, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; and Lixia Diao, Jing Wang, PhD, and Lauren A. Byers, MD, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.18.01153DOI Listing
January 2019

Differential Sensitivity Analysis for Resistant Malignancies (DISARM) Identifies Common Candidate Therapies across Platinum-Resistant Cancers.

Clin Cancer Res 2019 01 26;25(1):346-357. Epub 2018 Sep 26.

Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320267PMC
January 2019

Prognostic significance of pretreatment total lymphocyte count and neutrophil-to-lymphocyte ratio in extensive-stage small-cell lung cancer.

Radiother Oncol 2018 Mar 2;126(3):499-505. Epub 2018 Feb 2.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2017.12.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856620PMC
March 2018

Comparative study of lung and extrapulmonary poorly differentiated neuroendocrine carcinomas: A SEER database analysis of 162,983 cases.

Cancer 2018 02 6;124(4):807-815. Epub 2017 Dec 6.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://doi.wiley.com/10.1002/cncr.31124
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http://dx.doi.org/10.1002/cncr.31124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801102PMC
February 2018

HIRA deficiency in muscle fibers causes hypertrophy and susceptibility to oxidative stress.

J Cell Sci 2017 Aug 9;130(15):2551-2563. Epub 2017 Jun 9.

Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA

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http://dx.doi.org/10.1242/jcs.200642DOI Listing
August 2017

Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays.

Cancer Cell 2017 02;31(2):225-239

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501076PMC
February 2017

Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression.

Oncoimmunology 2016 26;5(11):e1234570. Epub 2016 Sep 26.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1234570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139626PMC
September 2016

Using reverse-phase protein arrays as pharmacodynamic assays for functional proteomics, biomarker discovery, and drug development in cancer.

Semin Oncol 2016 08 15;43(4):476-83. Epub 2016 Jun 15.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2016.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111873PMC
August 2016

Sequencing of mutational hotspots in cancer-related genes in small cell neuroendocrine cervical cancer.

Gynecol Oncol 2016 06 15;141(3):588-591. Epub 2016 Apr 15.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.ygyno.2016.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877250PMC
June 2016

Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer.

PLoS One 2016 7;11(4):e0152584. Epub 2016 Apr 7.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152584PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824499PMC
August 2016

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma.

Clin Cancer Res 2016 07 5;22(14):3630-42. Epub 2016 Feb 5.

Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947453PMC
July 2016

drexplorer: A tool to explore dose-response relationships and drug-drug interactions.

Bioinformatics 2015 May 18;31(10):1692-4. Epub 2015 Jan 18.

Departments of Bioinformatics and Computational Biology, Houston, TX 77030, Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43210, Thoracic and Head and Neck Medical Oncology and Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426846PMC
May 2015

A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma.

Mol Cancer Ther 2014 Nov 5;13(11):2738-50. Epub 2014 Sep 5.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-1090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221385PMC
November 2014

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

Nat Biotechnol 2014 Jul 22;32(7):644-52. Epub 2014 Jun 22.

1] Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USA. [2] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. [3].

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http://www.nature.com/articles/nbt.2940
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http://dx.doi.org/10.1038/nbt.2940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102885PMC
July 2014

Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer--response.

Clin Cancer Res 2014 Apr 31;20(8):2237. Epub 2014 Mar 31.

Authors' Affiliation: Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098859PMC
April 2014

Smoking, p53 mutation, and lung cancer.

Mol Cancer Res 2014 Jan;12(1):3-13

University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Box 0432, Houston, Texas 77030.

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http://dx.doi.org/10.1158/1541-7786.MCR-13-0539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925633PMC
January 2014

Progress in the management of limited-stage small cell lung cancer.

Cancer 2014 Mar 10;120(6):790-8. Epub 2013 Dec 10.

Department, of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; University of California at Irvine School of Medicine, Irvine, California.

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http://dx.doi.org/10.1002/cncr.28505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947683PMC
March 2014

HRAS mutations and resistance to the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in head and neck squamous cell carcinoma cells.

Head Neck 2014 Nov 20;36(11):1547-54. Epub 2014 Mar 20.

Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Otolaryngology - Head and Neck Surgery, Seoul National University Hospital and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1002/hed.23499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010580PMC
November 2014

Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer.

Clin Cancer Res 2013 Nov 27;19(22):6322-8. Epub 2013 Sep 27.

Authors' Affiliations: Department of Thoracic/Head and Neck Medical Oncology; Bioinformatics and Computational Biology; Systems Biology, UT MD Anderson Cancer Center, Houston; Hamon Center for Therapeutic Oncology Research and the Simmons Comprehensive Cancer Center, UT Southwestern, Dallas, Texas; and Biomarin Pharmaceuticals Inc., Novato, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882158PMC
November 2013

Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus.

PLoS One 2012 4;7(6):e36116. Epub 2012 Jun 4.

MCW Cancer Center, Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036116PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366984PMC
October 2012

Blasted cell line names.

Cancer Inform 2010 Oct 14;9:251-5. Epub 2010 Oct 14.

Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://journals.sagepub.com/doi/10.4137/CIN.S5613
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http://dx.doi.org/10.4137/CIN.S5613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978931PMC
October 2010

Dual targeting of the vascular endothelial growth factor and epidermal growth factor receptor pathways: rationale and clinical applications for non-small-cell lung cancer.

Clin Lung Cancer 2007 Feb;8 Suppl 2:S79-85

Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.3816/clc.2007.s.006DOI Listing
February 2007