Publications by authors named "Laurel Thomas"

25Publications

An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity.

Mol Cell 2018 12 8;72(6):985-998.e7. Epub 2018 Nov 8.

Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA; Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309500PMC
December 2018

A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis.

Am J Hum Genet 2018 05 12;102(5):995-1007. Epub 2018 Apr 12.

Centre de Génétique Médicale, Centre de Référence "Déficiences Intellectuelles de causes rares," CHU de Dijon Bourgogne, 21079 Dijon, France; Fédération Hospitalo-Universitaire Médecine Translationnelle et Anomalies du Développement (TRANSLAD), CHU de Dijon Bourgogne, 21079 Dijon, France; Inserm UMR1231 GAD, Génétique des Anomalies du Développement, Université de Bourgogne, 21079 Dijon, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986694PMC
May 2018

Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.

J Cell Sci 2017 Jun 5;130(11):1865-1876. Epub 2017 May 5.

Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada T6G2H7.

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http://dx.doi.org/10.1242/jcs.199463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482974PMC
June 2017

Suppression of calpain expression by NSAIDs is associated with inhibition of cell migration in rat duodenum.

Toxicology 2017 05 22;383:1-12. Epub 2017 Mar 22.

Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA.

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http://dx.doi.org/10.1016/j.tox.2017.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519291PMC
May 2017

Oral perfluorooctane sulfonate (PFOS) lessens tumor development in the APC mouse model of spontaneous familial adenomatous polyposis.

BMC Cancer 2016 12 8;16(1):942. Epub 2016 Dec 8.

Department of Epidemiology, School of Public Health, West Virginia University, Morgantown, WV, 26506, USA.

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http://dx.doi.org/10.1186/s12885-016-2861-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143440PMC
December 2016

Inhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration by disrupting calpain signaling.

Biochem Pharmacol 2015 Dec 7;98(4):614-28. Epub 2015 Nov 7.

Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States.

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http://dx.doi.org/10.1016/j.bcp.2015.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656099PMC
December 2015

The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.

Cell Rep 2014 Sep 21;8(5):1545-57. Epub 2014 Aug 21.

Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.07.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285392PMC
September 2014

Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen.

Retrovirology 2013 Nov 14;10:135. Epub 2013 Nov 14.

Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Bridgeside Point II, Suite 523, 15219, Pittsburgh, PA USA.

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http://dx.doi.org/10.1186/1742-4690-10-135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874621PMC
November 2013

A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking.

EMBO J 2006 Oct 14;25(19):4423-35. Epub 2006 Sep 14.

Vollum Institute, Oregon Health & Science University, Oregon Health Sciences University, Portland, 97239, USA.

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http://dx.doi.org/10.1038/sj.emboj.7601336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1589982PMC
October 2006

The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic.

EMBO J 2003 Dec;22(23):6234-44

Vollum Institute, L-474, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1093/emboj/cdg596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC291837PMC
December 2003

AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1.

EMBO Rep 2003 Dec 7;4(12):1182-9. Epub 2003 Nov 7.

Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1038/sj.embor.7400018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326413PMC
December 2003

Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production.

J Virol 2003 Oct;77(20):11105-13

Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC224974PMC
http://dx.doi.org/10.1128/jvi.77.20.11105-11113.2003DOI Listing
October 2003

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.

Cell 2002 Dec;111(6):853-66

Vollum Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/s0092-8674(02)01162-5DOI Listing
December 2002