Laure Segurel

Laure Segurel

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Laure Segurel

Laure Segurel

Publications by authors named "Laure Segurel"

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Close inbreeding and low genetic diversity in Inner Asian human populations despite geographical exogamy.

Sci Rep 2018 Jun 20;8(1):9397. Epub 2018 Jun 20.

Eco-anthropologie et Ethnobiologie, UMR 7206 CNRS, MNHN, Univ Paris Diderot, Sorbonne Paris Cité, Sorbonne Universités, 75016, Paris, France.

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http://dx.doi.org/10.1038/s41598-018-27047-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010435PMC
June 2018

Gut Protozoa: Friends or Foes of the Human Gut Microbiota?

Trends Parasitol 2017 12 1;33(12):925-934. Epub 2017 Sep 1.

UMR 7206 Eco-anthropologie et ethnobiologie, CNRS - MNHN - Paris Diderot University - Sorbonne Paris Cité, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2017.08.005DOI Listing
December 2017

[Importance of intestinal paleomicrobiome study for contemporaneous medical problematics].

Med Sci (Paris) 2017 Nov 4;33(11):984-990. Epub 2017 Dec 4.

UMR 7206 Éco-anthropologie et éthnobiologie. CNRS - Muséum National d'Histoire Naturelle - Univ Paris Diderot - Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1051/medsci/20173311016DOI Listing
November 2017

On the Evolution of Lactase Persistence in Humans.

Annu Rev Genomics Hum Genet 2017 08 19;18:297-319. Epub 2017 Apr 19.

Laboratoire Éco-Anthropologie et Ethnobiologie, UMR 7206 CNRS - Muséum national d'Histoire naturelle - Univ Paris Diderot, Sorbonne Paris Cité, F-75016 Paris, France; email: ,

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http://dx.doi.org/10.1146/annurev-genom-091416-035340DOI Listing
August 2017

Sex-specific genetic diversity is shaped by cultural factors in Inner Asian human populations.

Am J Phys Anthropol 2017 04 3;162(4):627-640. Epub 2017 Feb 3.

Eco-anthropologie et Ethnobiologie, UMR 7206 CNRS, MNHN, Univ Paris Diderot, Sorbonne Paris Cité, F-75016, Paris, France.

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http://dx.doi.org/10.1002/ajpa.23151DOI Listing
April 2017

Latitude as a co-driver of human gut microbial diversity?

Bioessays 2017 03 13;39(3). Epub 2017 Jan 13.

Eco-anthropologie et ethnobiologie, UMR 7206 CNRS - MNHN - Univ Paris Diderot, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1002/bies.201600145DOI Listing
March 2017

Detection and interpretation of shared genetic influences on 42 human traits.

Nat Genet 2016 07 16;48(7):709-17. Epub 2016 May 16.

23andMe, Inc., Mountain View, California, USA.

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http://dx.doi.org/10.1038/ng.3570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207801PMC
July 2016

Detection of Allelic Frequency Differences between the Sexes in Humans: A Signature of Sexually Antagonistic Selection.

Genome Biol Evol 2016 06 2;8(5):1489-500. Epub 2016 Jun 2.

Eco-Anthropologie et Ethnobiologie, UMR 7206 CNRS, MNHN, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1093/gbe/evw090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898804PMC
June 2016

Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence.

PLoS Genet 2015 Nov 30;11(11):e1005658. Epub 2015 Nov 30.

Eco-anthropology and Ethnobiology, Museum national d'Histoire naturelle, Centre national de la recherche scientifique, University Denis Diderot, Paris, France.

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http://dx.doi.org/10.1371/journal.pgen.1005658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664238PMC
November 2015

Determinants of mutation rate variation in the human germline.

Annu Rev Genomics Hum Genet 2014 5;15:47-70. Epub 2014 Jun 5.

Laboratoire Éco-Anthropologie et Ethnobiologie, UMR 7206, Muséum National d'Histoire Naturelle-Centre National de la Recherche Scientifique-Université Paris 7 Diderot, Paris 75231, France; email:

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http://www.annualreviews.org/doi/10.1146/annurev-genom-03171
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http://dx.doi.org/10.1146/annurev-genom-031714-125740DOI Listing
May 2015

Microsatellite data show recent demographic expansions in sedentary but not in nomadic human populations in Africa and Eurasia.

Eur J Hum Genet 2014 Oct 12;22(10):1201-7. Epub 2014 Feb 12.

Laboratoire d'Eco-Anthropologie et Ethnobiologie, UMR 7206, Muséum National d'Histoire Naturelle-Centre National de la Recherche Scientifique-Université Paris 7 Diderot, Paris, France.

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http://dx.doi.org/10.1038/ejhg.2014.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169540PMC
October 2014

Preserving immune diversity through ancient inheritance and admixture.

Curr Opin Immunol 2014 Oct 3;30:79-84. Epub 2014 Sep 3.

Unit of Human Evolutionary Genetics, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France; CNRS URA3012, 75015 Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09527915140010
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http://dx.doi.org/10.1016/j.coi.2014.08.002DOI Listing
October 2014

TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception.

Bioinformatics 2014 Jul 21;30(14):2035-42. Epub 2014 Mar 21.

Department of Human Genetics and Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA and Department of Biology, Spelman College, Atlanta, GA 30314, USADepartment of Human Genetics and Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA and Department of Biology, Spelman College, Atlanta, GA 30314, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080739PMC
July 2014

Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming.

Mol Biol Evol 2013 Dec 24;30(12):2629-44. Epub 2013 Sep 24.

Laboratoire Eco-Anthropologie et Ethnobiologie, UMR 7206, Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Université Paris 7 Diderot, Paris, France.

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http://dx.doi.org/10.1093/molbev/mst156DOI Listing
December 2013

Positive selection of protective variants for type 2 diabetes from the Neolithic onward: a case study in Central Asia.

Eur J Hum Genet 2013 Oct 23;21(10):1146-51. Epub 2013 Jan 23.

1] Eco-Anthropologie et Ethnobiologie, UMR 7206, Muséum National d'Histoire Naturelle - Centre National de la Recherche Scientifique - Université Paris 7 Diderot, Paris, France [2] Department of Human Genetics, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/ejhg.2012.295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778335PMC
October 2013

Ancestry runs deeper than blood: the evolutionary history of ABO points to cryptic variation of functional importance.

Bioessays 2013 Oct 9;35(10):862-7. Epub 2013 Jul 9.

Department of Human Genetics, University of Chicago, Chicago, IL, USA; Department of Ecology and Evolution, University of Chicago, Chicago, IL, USA; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1002/bies.201300030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034584PMC
October 2013

Revisiting an old riddle: what determines genetic diversity levels within species?

PLoS Biol 2012 11;10(9):e1001388. Epub 2012 Sep 11.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439417PMC
June 2013

The complex binding of PRDM9.

Authors:
Laure Ségurel

Genome Biol 2013 Apr 24;14(4):112. Epub 2013 Apr 24.

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http://dx.doi.org/10.1186/gb-2013-14-4-112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663109PMC
April 2013

The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans.

PLoS Biol 2011 Dec 6;9(12):e1001211. Epub 2011 Dec 6.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1371/journal.pbio.1001211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232208PMC
December 2011

Lactase persistence in central Asia: phenotype, genotype, and evolution.

Hum Biol 2011 Jun;83(3):379-92

Eco-anthropology and Ethnobiology Unit, Muséum National d'Histoire Naturelle, Université Paris Diderot, France.

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http://dx.doi.org/10.3378/027.083.0304DOI Listing
June 2011

In the heartland of Eurasia: the multilocus genetic landscape of Central Asian populations.

Eur J Hum Genet 2011 Feb 8;19(2):216-23. Epub 2010 Sep 8.

Muséum National d'Histoire Naturelle - Centre National de la Recherche Scientifique-Université Paris 7, UMR 7206, Éco-Anthropologie et Ethnobiologie, Paris, France.

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http://dx.doi.org/10.1038/ejhg.2010.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025785PMC
February 2011

Frequency of the AGT Pro11Leu polymorphism in humans: Does diet matter?

Ann Hum Genet 2010 Jan;74(1):57-64

Muséum National d'Histoire Naturelle-Centre National de la Recherche Scientifique-Université Paris Diderot-Paris, UMR Eco-Anthropologie et Ethnobiologie, France.

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http://dx.doi.org/10.1111/j.1469-1809.2009.00549.xDOI Listing
January 2010

Looking for signatures of sex-specific demography and local adaptation on the X chromosome.

Genome Biol 2010 Jan 28;11(1):203. Epub 2010 Jan 28.

Human Population Genetics Team, UMR 7206 EcoAnthropologie MNHN/CNRS/UPD, 57 rue Cuvier, 75005 Paris, France.

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http://dx.doi.org/10.1186/gb-2010-11-1-203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847711PMC
January 2010

Genetic diversity and the emergence of ethnic groups in Central Asia.

BMC Genet 2009 Sep 1;10:49. Epub 2009 Sep 1.

Eco-anthropologie et Ethnobiologie, UMR7206 Département Hommes Natures Sociétés, Musée de l'Homme - 17, Place du Trocadéro - 75116 Paris, France.

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http://link.springer.com/content/pdf/10.1186/1471-2156-10-49
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http://www.biomedcentral.com/1471-2156/10/49
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http://dx.doi.org/10.1186/1471-2156-10-49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745423PMC
September 2009

Sex-specific genetic structure and social organization in Central Asia: insights from a multi-locus study.

PLoS Genet 2008 Sep 26;4(9):e1000200. Epub 2008 Sep 26.

Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique UMR 5145, Université Paris 7, Eco-Anthropologie et Ethnobiologie, Musée de l'Homme, Paris, France.

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http://dx.doi.org/10.1371/journal.pgen.1000200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535577PMC
September 2008