Publications by authors named "Laure Elens"

61Publications

Optimal sampling strategies for darunavir and external validation of the underlying population pharmacokinetic model.

Eur J Clin Pharmacol 2020 Nov 11. Epub 2020 Nov 11.

Integrated PharmacoMetrics, PharmacoGenomics and PharmacoKinetics, Louvain Drug Research Institute, Université catholique de Louvain, Avenue E. Mounier 72, B01.72.0, Brussels, Belgium.

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November 2020

Predictors of tacrolimus pharmacokinetic variability: current evidences and future perspectives.

Expert Opin Drug Metab Toxicol 2020 Sep 3;16(9):769-782. Epub 2020 Sep 3.

Integrated Pharmacometrics, Pharmacogenomics and Pharmacokinetics (PMGK), Louvain Drug Research Institute (LDRI), Université Catholique De Louvain , Brussels, Belgium.

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September 2020

Exploration of Reduced Doses and Short-Cycle Therapy for Darunavir/Cobicistat in Patients with HIV Using Population Pharmacokinetic Modeling and Simulations.

Clin Pharmacokinet 2020 Jul 22. Epub 2020 Jul 22.

Integrated PharmacoMetrics, PharmacoGenomics and PharmacoKinetics, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.

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July 2020

Should We Treat Bacteremic Prostatitis for 7 Days?

Clin Infect Dis 2020 01;70(2):351

Division of Internal Medicine and Infectious Disease, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

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January 2020

Rivaroxaban plasma levels in patients admitted for bleeding events: insights from a prospective study.

Thromb J 2018 12;16:28. Epub 2018 Nov 12.

7CHU UCL Namur, Namur Thrombosis and Hemostasis Center, Hematology Laboratory, Université catholique de Louvain, Yvoir, Belgium.

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November 2018

Cytochrome P450 genotype and aggressive behavior on selective serotonin reuptake inhibitors.

Pharmacogenomics 2018 09 31;19(14):1097-1099. Epub 2018 Aug 31.

Department of Clinical Chemistry, Erasmus University Medical Centre, Rotterdam, The Netherlands.

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September 2018

Effect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines.

Sci Rep 2018 Jul 12;8(1):10514. Epub 2018 Jul 12.

Louvain Centre for Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, UCL, Brussels, Belgium.

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July 2018

Pharmacogenetic associations with cytochrome P450 in antiretroviral therapy: what does the future hold?

Expert Opin Drug Metab Toxicol 2018 Jun 28;14(6):601-611. Epub 2018 May 28.

a Integrated Pharmacometrics, Pharmacogenomics and Pharmacokinetics , Louvain Drug Research Institute, Université catholique de Louvain , Brussels , Belgium.

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June 2018

Detection of a rare CYP3A4 variant in a transplant patient characterized by a tacrolimus poor metabolizer phenotype.

Pharmacogenomics 2018 03 22;19(4):305-310. Epub 2018 Feb 22.

Department of Integrated PharmacoMetrics, PharmacoGenomics & PharmacoKinetics (PMGK), Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCL), Brussels, Belgium.

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March 2018

Genotype-based tacrolimus dosing guidelines: with or without CYP3A4*22?

Pharmacogenomics 2017 Nov 2;18(16):1473-1480. Epub 2017 Nov 2.

Louvain Centre for Toxicology & Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, 1200 Brussels, Belgium.

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November 2017

Advanced cancer pain: the search for genetic factors correlated with interindividual variability in opioid requirement.

Pharmacogenomics 2017 Aug 26;18(12):1133-1142. Epub 2017 Jul 26.

Department of Clinical Chemistry, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.

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August 2017

The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation.

Pharmacogenet Genomics 2017 Sep;27(9):313-322

Departments of aNephrology bPharmacy, IDIBELL, Bellvitge University Hospital cDepartment of Pharmacy and Pharmaceutical Technology, Biopharmaceutics and Pharmacokinetics Unit, School of Pharmacy, University of Barcelona, Barcelona, Spain dDepartment of Integrated PharmacoMetrics, PharmacoGenomics and PharmacoKinetics, Louvain Drug Research Institute eLouvain Centre for Toxicology and Applied Pharmacology, Experimental and Clinical Research Institute, Catholic University of Louvain, Brussels, Belgium Departments of fInternal Medicine gHospital Pharmacy hClinical Biochemistry, Erasmus MC, University Medical Center Rotterdam, The Netherlands.

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September 2017

Tacrolimus Updated Guidelines through popPK Modeling: How to Benefit More from CYP3A Pre-emptive Genotyping Prior to Kidney Transplantation.

Front Pharmacol 2017 8;8:358. Epub 2017 Jun 8.

Louvain Centre for Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université catholique de LouvainBrussels, Belgium.

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June 2017

A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach.

Clin Pharmacokinet 2017 08;56(8):963-975

Laboratory 4122, Nephrology Service and Laboratory of Experimental Nephrology, University of Barcelona, Campus Bellvitge, Pavelló de Govern, Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907, Barcelona, Spain.

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August 2017

Interaction between Darunavir and Etravirine Is Partly Mediated by CYP3A5 Polymorphism.

PLoS One 2016 27;11(10):e0165631. Epub 2016 Oct 27.

Louvain centre for Toxicology and Applied Pharmacology, Institut de recherche expérimentale et clinique, Université catholique de Louvain, Brussels, Belgium.

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June 2017