Publications by authors named "Laura Sturla"

42Publications

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.

FASEB J 2019 03 4;33(3):3704-3717. Epub 2018 Dec 4.

Section of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.

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March 2019

Chronic Intake of Micrograms of Abscisic Acid Improves Glycemia and Lipidemia in a Human Study and in High-Glucose Fed Mice.

Nutrients 2018 Oct 12;10(10). Epub 2018 Oct 12.

Department of Internal Medicine, IRCCS Ospedale San Martino, Largo R. Benzi 1, 16132 Genova, Italy.

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October 2018

Identification of a high affinity binding site for abscisic acid on human lanthionine synthetase component C-like protein 2.

Int J Biochem Cell Biol 2018 04 5;97:52-61. Epub 2018 Feb 5.

Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV 3, 16132, Genoa, Italy. Electronic address:

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April 2018

Abscisic acid enhances cold tolerance in honeybee larvae.

Proc Biol Sci 2017 Apr;284(1852)

Instituto de Investigaciones Biológicas, CONICET - Universidad Nacional de Mar del Plata (UNMdP), CC 1245, 7600 Mar del Plata, Argentina

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April 2017

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.

Eur J Med Chem 2015 Sep 14;102:530-9. Epub 2015 Aug 14.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy; Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129 Bologna, Italy. Electronic address:

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September 2015

Fluridone as a new anti-inflammatory drug.

Eur J Pharmacol 2013 Nov 6;720(1-3):7-15. Epub 2013 Nov 6.

Department of Experimental Medicine, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy. Electronic address:

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November 2013

The diadenosine homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-Tooth type 1A.

J Cell Biochem 2014 Jan;115(1):161-7

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Mother and Child Sciences and CEBR, University of Genova, Genova, Italy.

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January 2014

CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.

J Biol Chem 2013 Sep 23;288(36):25938-49. Epub 2013 Jul 23.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.

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September 2013

Abscisic acid ameliorates the systemic sclerosis fibroblast phenotype in vitro.

Biochem Biophys Res Commun 2012 May 27;422(1):70-4. Epub 2012 Apr 27.

Department of Experimental Medicine, Section of Biochemistry, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.

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May 2012

NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes.

J Biol Chem 2012 Jun 30;287(25):21067-81. Epub 2012 Apr 30.

Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy.

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June 2012

Autocrine abscisic acid plays a key role in quartz-induced macrophage activation.

FASEB J 2012 Mar 31;26(3):1261-71. Epub 2011 Oct 31.

DIMES, Section of Biochemistry, University of Genova, Viale Benedetto XV, 1 16132 Genova, Italy.

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March 2012

Binding of abscisic acid to human LANCL2.

Biochem Biophys Res Commun 2011 Nov 20;415(2):390-5. Epub 2011 Oct 20.

Department of Experimental Medicine (DIMES), Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy.

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November 2011

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells.

J Biol Chem 2009 Oct 10;284(41):28045-57. Epub 2009 Aug 10.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, Genova 16132, Italy.

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October 2009

P2X7-mediated increased intracellular calcium causes functional derangement in Schwann cells from rats with CMT1A neuropathy.

J Biol Chem 2009 Aug 22;284(34):23146-58. Epub 2009 Jun 22.

Department of Neurosciences, Ophthalmology, and Genetics and Center of Excellence for Biomedical Research, University of Genova, Via De Toni 5, 16132 Genova, Italy.

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August 2009

Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis.

J Biol Chem 2009 Jun 30;284(26):17808-18. Epub 2009 Mar 30.

Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genova, and Vascular and Endovascular Surgery Unit, San Martino Hospital, Viale Benedetto XV 1, 16132 Genova, Italy.

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June 2009

Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses.

J Biol Chem 2008 Jan 1;283(1):184-93. Epub 2007 Nov 1.

Department of Experimental Medicine, University of Genoa and Center of Excellence for Biomedical Research, Viale Benedetto XV 1, 16132 Genoa, Italy.

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January 2008

Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.

J Biol Chem 2006 Oct 22;281(42):31419-29. Epub 2006 Aug 22.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV/1, 16132 Genova, Italy.

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October 2006

Quaternary assembly and crystal structure of GDP-D-mannose 4,6 dehydratase from Paramecium bursaria Chlorella virus.

Biochem Biophys Res Commun 2006 Jan 10;339(1):191-5. Epub 2005 Nov 10.

Bioinformatics and Structural Proteomics, National Institute for Cancer Research (IST), Largo R. Benzi 10, 16132 Genoa, Italy.

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January 2006

Core fucosylation of N-linked glycans in leukocyte adhesion deficiency/congenital disorder of glycosylation IIc fibroblasts.

Glycobiology 2005 Oct 25;15(10):924-34. Epub 2005 May 25.

Department of Experimental Medicine,and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 1, 16132, Genova, Italy.

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October 2005

Concentrative influx of functionally active cyclic ADP-ribose in dimethyl sulfoxide-differentiated HL-60 cells.

J Biol Chem 2004 May 17;279(21):22066-75. Epub 2004 Mar 17.

Department of Experimental Medicine, University of Genova, Viale Benedetto XV/1, Genova, Italy.

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May 2004

Paramecium bursaria Chlorella virus 1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose.

J Biol Chem 2003 Jun 4;278(24):21559-65. Epub 2003 Apr 4.

Department of Experimental Medicine, Section of Biochemistry and Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.

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June 2003

Equilibrative and concentrative nucleoside transporters mediate influx of extracellular cyclic ADP-ribose into 3T3 murine fibroblasts.

J Biol Chem 2002 Dec 3;277(49):47097-105. Epub 2002 Oct 3.

Department of Experimental Medicine, Section of Biochemistry, University of Genova, Italy.

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December 2002