Laura Renkonen-Sinisalo

Laura Renkonen-Sinisalo

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Laura Renkonen-Sinisalo

Laura Renkonen-Sinisalo

Publications by authors named "Laura Renkonen-Sinisalo"

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45Publications

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Is there a need for neoadjuvant short-course radiotherapy in T3 rectal cancer with positive lymph node involvement? A single-center retrospective cohort study.

World J Surg Oncol 2019 Aug 8;17(1):139. Epub 2019 Aug 8.

Colorectal Surgery, Abdominal Centre, Helsinki University Hospital, Haartmaninkatu 4, PL340, 00029 HUS, Helsinki, Finland.

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http://dx.doi.org/10.1186/s12957-019-1670-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688332PMC
August 2019

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Genet Med 2019 Jul 24. Epub 2019 Jul 24.

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41436-019-0596-9DOI Listing
July 2019

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Nat Commun 2019 05 14;10(1):2154. Epub 2019 May 14.

Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://www.nature.com/articles/s41467-019-09775-w
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http://dx.doi.org/10.1038/s41467-019-09775-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517433PMC
May 2019

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report.

Hered Cancer Clin Pract 2019 28;17. Epub 2019 Feb 28.

4Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway.

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https://hccpjournal.biomedcentral.com/articles/10.1186/s1305
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http://dx.doi.org/10.1186/s13053-019-0106-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394091PMC
February 2019

Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance.

Mod Pathol 2018 08 27;31(8):1291-1301. Epub 2018 Mar 27.

Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/s41379-018-0044-4DOI Listing
August 2018

Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas.

Gynecol Oncol 2018 07 30;150(1):92-98. Epub 2018 Apr 30.

Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ygyno.2018.04.566DOI Listing
July 2018

Subtotal Colectomy for Colon Cancer Reduces the Need for Subsequent Surgery in Lynch Syndrome.

Dis Colon Rectum 2017 Aug;60(8):792-799

1 Department of Gastrointestinal Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland 2 Research Programs Unit, Genome-Scale Biology, University of Helsinki, Helsinki, Finland 3 Department of Education and Science, Central Finland Health Care District, Jyväskylä Finland and University of Eastern Finland, Finland.

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http://dx.doi.org/10.1097/DCR.0000000000000802DOI Listing
August 2017

Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis.

J Surg Oncol 2016 Feb 10;113(2):209-12. Epub 2015 Dec 10.

Department of Colorectal Surgery, Abdominal Center, Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1002/jso.24117DOI Listing
February 2016

Low anterior resection combined with a covering stoma in the treatment of rectal cancer reduces the risk of permanent anastomotic failure.

Int J Colorectal Dis 2015 Oct 26;30(10):1323-8. Epub 2015 Jun 26.

Colorectal Surgery, Abdominal Center, Helsinki University Hospital, Kasarmikatu 11-13, Pl 263, 00029, Helsinki, Finland.

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http://link.springer.com/10.1007/s00384-015-2291-x
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http://dx.doi.org/10.1007/s00384-015-2291-xDOI Listing
October 2015

CTCF/cohesin-binding sites are frequently mutated in cancer.

Nat Genet 2015 Jul 8;47(7):818-21. Epub 2015 Jun 8.

1] Genome-Scale Biology Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland. [2] Department of Medical and Clinical Genetics, Medicum, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/ng.3335DOI Listing
July 2015

Pattern of rectal cancer recurrence after curative surgery.

Int J Colorectal Dis 2015 Jun 22;30(6):775-85. Epub 2015 Mar 22.

Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland,

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http://dx.doi.org/10.1007/s00384-015-2182-1DOI Listing
June 2015

Systematic search for rare variants in Finnish early-onset colorectal cancer patients.

Cancer Genet 2015 Jan-Feb;208(1-2):35-40. Epub 2014 Dec 31.

Department of Medical Genetics, Genome-Scale Biology Program, University of Helsinki, Biomedicum, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2014.12.004DOI Listing
May 2015

Distinct molecular profiles in Lynch syndrome-associated and sporadic ovarian carcinomas.

Int J Cancer 2013 Dec 21;133(11):2596-608. Epub 2013 Jun 21.

Department of Medical Genetics, Haartman Institute, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/ijc.28287DOI Listing
December 2013

Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients.

Scand J Gastroenterol 2013 Jun 2;48(6):672-8. Epub 2013 Apr 2.

Department of Medical Genetics, Genome-Scale Biology Program, University of Helsinki, Biomedicum, P.O. Box 63, FIN-00014 University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.3109/00365521.2013.783102DOI Listing
June 2013

Ten years after mutation testing for Lynch syndrome: cancer incidence and outcome in mutation-positive and mutation-negative family members.

J Clin Oncol 2009 Oct 31;27(28):4793-7. Epub 2009 Aug 31.

Department of Surgery, University of Helsinki, FI-00029 HUS, Helsinki, Finland.

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http://dx.doi.org/10.1200/JCO.2009.23.7784DOI Listing
October 2009

Utility of computed tomographic colonography in surveillance for hereditary nonpolyposis colorectal cancer syndrome.

Fam Cancer 2007 ;6(1):135-40

Department of Surgery, Helsinki University Central Hospital, Haartmaninkatu 4, PL 340, 00029 HUS Helsinki, Finland.

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http://dx.doi.org/10.1007/s10689-007-9116-1DOI Listing
September 2007

Surveillance for endometrial cancer in hereditary nonpolyposis colorectal cancer syndrome.

Int J Cancer 2007 Feb;120(4):821-4

Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1002/ijc.22446DOI Listing
February 2007