Laura Passerini

Laura Passerini

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Laura Passerini

Laura Passerini

Publications by authors named "Laura Passerini"

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Role of human forkhead box P3 in early thymic maturation and peripheral T-cell homeostasis.

J Allergy Clin Immunol 2018 12 27;142(6):1909-1921.e9. Epub 2018 Apr 27.

San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy; Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford School of Medicine, Stanford, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.03.015DOI Listing
December 2018

Forkhead-Box-P3 Gene Transfer in Human CD4 T Conventional Cells for the Generation of Stable and Efficient Regulatory T Cells, Suitable for Immune Modulatory Therapy.

Front Immunol 2017 12;8:1282. Epub 2017 Oct 12.

Department of Stem Cell Transplantation and Regenerative Medicine, Division of Pediatrics, Stanford School of Medicine, Stanford, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2017.01282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643480PMC
October 2017

Clinical Outlook for Type-1 and FOXP3(+) T Regulatory Cell-Based Therapy.

Front Immunol 2015 25;6:593. Epub 2015 Nov 25.

Department of Pediatric Stem Cell Transplantation and Regenerative Medicine, Stanford School of Medicine , Palo Alto, CA , USA.

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http://dx.doi.org/10.3389/fimmu.2015.00593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658444PMC
December 2015

Gene/cell therapy approaches for Immune Dysregulation Polyendocrinopathy Enteropathy X-linked syndrome.

Curr Gene Ther 2014 ;14(6):422-8

San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20131, Milan, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443799PMC
July 2015

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3.

Blood 2015 Jun 1;125(25):3886-95. Epub 2015 Apr 1.

Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA; Department of Medicine, Harvard Medical School, Boston, MA; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1182/blood-2014-12-618363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473116PMC
June 2015

Forkhead box P3: the peacekeeper of the immune system.

Int Rev Immunol 2014 Mar 19;33(2):129-45. Epub 2013 Dec 19.

1Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.3109/08830185.2013.863303DOI Listing
March 2014

CD4⁺ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer.

Sci Transl Med 2013 Dec;5(215):215ra174

San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan 20132, Italy.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30073
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http://dx.doi.org/10.1126/scitranslmed.3007320DOI Listing
December 2013

Immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome: a paradigm of immunodeficiency with autoimmunity.

Front Immunol 2012 31;3:211. Epub 2012 Jul 31.

Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute Milan, Italy ; Vita Salute San Raffaele University Milan, Italy.

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http://dx.doi.org/10.3389/fimmu.2012.00211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459184PMC
October 2012

Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome.

Eur J Immunol 2011 Apr 14;41(4):1120-31. Epub 2011 Mar 14.

San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1002/eji.201040909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107421PMC
April 2011

Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.

J Allergy Clin Immunol 2010 Dec 30;126(6):1242-51. Epub 2010 Oct 30.

Department of Surgery, University of British Columbia, and Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S009167491001342
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http://dx.doi.org/10.1016/j.jaci.2010.09.001DOI Listing
December 2010

Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations.

Blood 2009 Nov 8;114(19):4138-41. Epub 2009 Sep 8.

San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, 58-20132 Milan, Italy.

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http://dx.doi.org/10.1182/blood-2009-04-214593DOI Listing
November 2009

Isolation, expansion, and characterization of human natural and adaptive regulatory T cells.

Methods Mol Biol 2007 ;380:83-105

San Raffaele Telethon Institute for Gene Therapy, Milan, Italy.

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http://dx.doi.org/10.1007/978-1-59745-395-0_6DOI Listing
April 2008

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.

Int Immunol 2008 Mar 12;20(3):421-31. Epub 2008 Feb 12.

San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1093/intimm/dxn002DOI Listing
March 2008

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production.

Int Immunol 2007 Apr 27;19(4):345-54. Epub 2007 Feb 27.

Department of Surgery, University of British Columbia, and Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, 2660 Oak Street, Vancouver, Canada.

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http://dx.doi.org/10.1093/intimm/dxm014DOI Listing
April 2007

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.

J Clin Invest 2005 Nov 6;115(11):3276-84. Epub 2005 Oct 6.

Department of Surgery, University of British Columbia, and Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1172/JCI24685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1242190PMC
November 2005

Structure-activity relationships for the mutagenicity and carcinogenicity of simple and alpha-beta unsaturated aldehydes.

Environ Mol Mutagen 2003 ;42(3):136-43

Laboratory of Comparative Toxicology and Ecotoxicology, Istituto Superiore di Sanita', Rome, Italy.

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http://dx.doi.org/10.1002/em.10190DOI Listing
December 2003

Analysis of SjTREC levels in thymus from MG patients and normal children.

Ann N Y Acad Sci 2003 Sep;998:270-4

Immunology and Muscular Pathology Unit, Istituto Nazionale Neurologico Carlo Besta, 20133 Milan, Italy.

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http://dx.doi.org/10.1196/annals.1254.029DOI Listing
September 2003

Expression of transforming growth factor-beta1 in thymus of myasthenia gravis patients: correlation with pathological abnormalities.

Ann N Y Acad Sci 2003 Sep;998:278-83

Immunology and Muscular Pathology Unit, Istituto Nazionale Neurologico Carlo Besta, 20133 Milan, Italy.

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http://dx.doi.org/10.1196/annals.1254.031DOI Listing
September 2003

Looking for an unambiguous geometrical definition of organic series from 3-d molecular similarity indices.

J Chem Inf Comput Sci 2003 Jan-Feb;43(1):248-54

Laboratory of Pharmaceutical Chemistry, and Laboratory of Comparative Toxicology and Ecotoxicology, Istituto Superiore di Sanita', Viale Regina Elena 299, 00161 Rome - Italy.

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http://dx.doi.org/10.1021/ci020375zDOI Listing
April 2003

Fibrogenic cytokines and extent of fibrosis in muscle of dogs with X-linked golden retriever muscular dystrophy.

Neuromuscul Disord 2002 Nov;12(9):828-35

Myopathology and Immunology Unit, Istituto Nazionale Neurologico 'Carlo Besta', Via Celoria 11, 20133, Milan, Italy.

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November 2002

Carcinogenicity of the aromatic amines: from structure-activity relationships to mechanisms of action and risk assessment.

Mutat Res 2002 Jul;511(3):191-206

Laboratory of Comparative Toxicology and Ecotoxicology, Istituto Superiore di Sanita', Viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.1016/s1383-5742(02)00008-xDOI Listing
July 2002