Laura Fratiglioni

Laura Fratiglioni

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Laura Fratiglioni

Laura Fratiglioni

Publications by authors named "Laura Fratiglioni"

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Specific nutrient patterns are associated with higher structural brain integrity in dementia-free older adults.

Neuroimage 2019 Oct 30;199:281-288. Epub 2019 May 30.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Tomtebodavägen 18A Floor 10, SE-171 65, Solna, Stockholm, Sweden; Department of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2019.05.066DOI Listing
October 2019

Measuring gait speed to better identify prodromal dementia.

Exp Gerontol 2019 Sep 4;124:110625. Epub 2019 Jun 4.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Centro Medicina dell'Invecchiamento, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, and Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2019.05.014DOI Listing
September 2019

Using an Integrated Clinical and Functional Assessment Tool to Describe the Use of Social and Medical Care in an Urban Community-Dwelling Swedish Older Population.

J Am Med Dir Assoc 2019 Aug 17;20(8):988-994.e2. Epub 2019 Jan 17.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2018.11.017DOI Listing
August 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Aug 15. Epub 2019 Aug 15.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
August 2019

Combining Cognitive, Genetic, and Structural Neuroimaging Markers to Identify Individuals with Increased Dementia Risk.

J Alzheimers Dis 2018 ;64(2):533-542

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.3233/JAD-180199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027943PMC
July 2019

Genetic risk of dementia mitigated by cognitive reserve: A cohort study.

Ann Neurol 2019 Jul 22;86(1):68-78. Epub 2019 May 22.

Aging Research Center, Department of Neurobiology, Care Sciences, and Society, Karolinska Institute and Stockholm University, Stockholm, Sweden.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ana.25501
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http://dx.doi.org/10.1002/ana.25501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618249PMC
July 2019

Call for articles on neglected topics.

Ageing Res Rev 2019 Jul 15:100934. Epub 2019 Jul 15.

Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; C.I.G. Interdepartmental Centre "L. Galvani", Alma Mater Studiorum, University of Bologna, Bologna, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2019.100934DOI Listing
July 2019

Impact of Social Network on the Risk and Consequences of Injurious Falls in Older Adults.

J Am Geriatr Soc 2019 Jun 26. Epub 2019 Jun 26.

Department of Neurobiology, Care Sciences and Society, Aging Research Center (ARC), Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jgs.16018DOI Listing
June 2019

Aging without Dementia is Achievable: Current Evidence from Epidemiological Research.

J Alzheimers Dis 2018 ;62(3):933-942

Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet-Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.3233/JAD-171037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870011PMC
May 2019

Predicting Cognitive and Functional Trajectories in People With Late-Onset Dementia: 2 Population-Based Studies.

J Am Med Dir Assoc 2019 May 17. Epub 2019 May 17.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2019.03.025DOI Listing
May 2019

Walking Speed Drives the Prognosis of Older Adults with Cardiovascular and Neuropsychiatric Multimorbidity.

Am J Med 2019 May 27. Epub 2019 May 27.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden; Stockholm Gerontology Research Center, Sweden.

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http://dx.doi.org/10.1016/j.amjmed.2019.05.005DOI Listing
May 2019

Glutathione Serum Levels and Rate of Multimorbidity Development in Older Adults.

J Gerontol A Biol Sci Med Sci 2019 Apr 25. Epub 2019 Apr 25.

Aging Research Center, NVS Department, Karolinska Institutet, Stockholm University, Sweden.

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http://dx.doi.org/10.1093/gerona/glz101DOI Listing
April 2019

Association Between Speed of Multimorbidity Accumulation in Old Age and Life Experiences: A Cohort Study.

Am J Epidemiol 2019 Apr 24. Epub 2019 Apr 24.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1093/aje/kwz101DOI Listing
April 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Cardiovascular Risk Factors and the Risk of Disability in Older Adults: Variation by Age and Functional Status.

J Am Med Dir Assoc 2019 Feb 10;20(2):208-212.e3. Epub 2018 Jul 10.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, and Stockholm University, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2018.05.013DOI Listing
February 2019

A bi-factor model of the Montgomery Åsberg depression rating scale and future cognitive impairments in older adults: A 6-year follow-up study.

J Psychiatr Res 2019 Feb 10;109:1-9. Epub 2018 Nov 10.

Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden; Stress Research Institute, Stockholm University, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223956183041
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http://dx.doi.org/10.1016/j.jpsychires.2018.11.010DOI Listing
February 2019

Risk Factors for Injurious Falls in Older Adults: The Role of Sex and Length of Follow-Up.

J Am Geriatr Soc 2019 Feb 29;67(2):246-253. Epub 2018 Nov 29.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jgs.15657DOI Listing
February 2019

Participating in Mental, Social, and Physical Leisure Activities and Having a Rich Social Network Reduce the Incidence of Diabetes-Related Dementia in a Cohort of Swedish Older Adults.

Diabetes Care 2019 02 6;42(2):232-239. Epub 2018 Dec 6.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden

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http://dx.doi.org/10.2337/dc18-1428DOI Listing
February 2019

Prediabetes and diabetes accelerate cognitive decline and predict microvascular lesions: A population-based cohort study.

Alzheimers Dement 2019 01 13;15(1):25-33. Epub 2018 Aug 13.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.06.3060DOI Listing
January 2019

Working Life Psychosocial Conditions in Relation to Late-Life Cognitive Decline: A Population-Based Cohort Study.

J Alzheimers Dis 2019 ;67(1):315-325

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
Publisher Site
http://dx.doi.org/10.3233/JAD-180870DOI Listing
January 2019

Sleep disturbances and later cognitive status: a multi-centre study.

Sleep Med 2018 Dec 3;52:26-33. Epub 2018 Jan 3.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Institute of Gerontology, School of Health and Welfare, Aging Research Network - Jönköping (ARN-J), Jönköping University, Jönköping, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S13899457173160
Publisher Site
http://dx.doi.org/10.1016/j.sleep.2017.11.1149DOI Listing
December 2018

Geriatric health charts for individual assessment and prediction of care needs: a population-based prospective study.

J Gerontol A Biol Sci Med Sci 2018 12 4. Epub 2018 Dec 4.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Tomtebodavägen 18 A, 171 65 Solna, Sweden.

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http://dx.doi.org/10.1093/gerona/gly272DOI Listing
December 2018

The impact of nutrient-based dietary patterns on cognitive decline in older adults.

Clin Nutr 2018 Dec 14. Epub 2018 Dec 14.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institute and Stockholm University, Sweden; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183258
Publisher Site
http://dx.doi.org/10.1016/j.clnu.2018.12.012DOI Listing
December 2018

Atrial fibrillation, antithrombotic treatment, and cognitive aging: A population-based study.

Neurology 2018 11 10;91(19):e1732-e1740. Epub 2018 Oct 10.

From the Aging Research Center (M.D., L.F., K.J., G.S., J.F., A.M., C.Q.), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University; Stockholm Gerontology Research Center (L.F.), Stockholm; Institute of Environmental Medicine (P.L.), Karolinska Institutet, Stockholm; Department of Cardiology (P.L.), Danderyd Hospital, Stockholm, Sweden; and Department of Clinical and Experimental Sciences (A.M.), University of Brescia, Italy.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000006456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251601PMC
November 2018

Frailty predicts short-term survival even in older adults without multimorbidity.

Eur J Intern Med 2018 10 24;56:53-56. Epub 2018 Jun 24.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, 11330 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ejim.2018.06.012DOI Listing
October 2018

Sleep disturbances and dementia risk: A multicenter study.

Alzheimers Dement 2018 10 17;14(10):1235-1242. Epub 2018 Jul 17.

Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden; Neuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, United Kingdom; Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.

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https://linkinghub.elsevier.com/retrieve/pii/S15525260183021
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http://dx.doi.org/10.1016/j.jalz.2018.05.012DOI Listing
October 2018

MRI load of cerebral microvascular lesions and neurodegeneration, cognitive decline, and dementia.

Neurology 2018 10 19;91(16):e1487-e1497. Epub 2018 Sep 19.

From the Department of Neurobiology (R.W., E.J.L., G.K., L.B., L.F., C.Q.), Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm University; Division of Radiology (A.L.), Department of Clinical Science, Intervention and Technology, Karolinska University Hospital at Huddinge; Department of Neuroradiology (A.L.), Karolinska University Hospital, Stockholm; and Stockholm Gerontology Research Center (L.F.), Stockholm, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000006355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202944PMC
October 2018

Temporal trends in impairments of physical function among older adults during 2001-16 in Sweden: towards a healthier ageing.

Age Ageing 2018 09;47(5):698-704

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/ageing/afy085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108390PMC
September 2018

An Active Lifestyle Reinforces the Effect of a Healthy Diet on Cognitive Function: A Population-Based Longitudinal Study.

Nutrients 2018 Sep 13;10(9). Epub 2018 Sep 13.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet/Stockholm University, Widerströmskahuset, plan 10, Tomtebodavägen 18A, 171 65 Solna, Sweden.

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http://dx.doi.org/10.3390/nu10091297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163666PMC
September 2018

Antihypertensive Medication Regimen Intensity and Incident Dementia in an Older Population.

J Am Med Dir Assoc 2018 Jul 3;19(7):577-583. Epub 2018 Jan 3.

Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jamda.2017.11.017DOI Listing
July 2018

The Effect of a 2-Year Intervention Consisting of Diet, Physical Exercise, Cognitive Training, and Monitoring of Vascular Risk on Chronic Morbidity-the FINGER Randomized Controlled Trial.

J Am Med Dir Assoc 2018 Apr 3;19(4):355-360.e1. Epub 2017 Nov 3.

Department of Public Health Solutions, Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jamda.2017.09.020DOI Listing
April 2018

Same Ages, Same Genes: Same Brains, Same Pathologies?: Dementia Timings, Co-Occurring Brain Pathologies, ApoE Genotypes in Identical and Fraternal Age-matched Twins at Autopsy.

Alzheimer Dis Assoc Disord 2016 Apr-Jun;30(2):178-82

*Department NVS, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge∥Department of Pathology, Karolinska University Hospital¶Department of Medical Epidemiology and Biostatistics, Karolinska Institutet#Aging Research Center (ARC), Karolinska Institutet/Stockholm University, Stockholm**Department of Psychology, University of Göthenburg, Göthenburg††Department of Geriatric Rehabilitation, Värnamo Hospital, Värnamo, Sweden†Neuropathology Research, Biomedical Research Institute of New Jersey, BRInj, Cedar Knolls‡Atlantic Neuroscience Institute, Atlantic Health System, Overlook and Morristown Medical Center, Morristown, NJ§Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY‡‡Department of Psychology, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/WAD.0000000000000114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840096PMC
March 2018

Cognitive Trajectories of Older Adults With Prediabetes and Diabetes: A Population-Based Cohort Study.

J Gerontol A Biol Sci Med Sci 2018 03;73(3):400-406

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden.

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http://dx.doi.org/10.1093/gerona/glx112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861913PMC
March 2018

Trajectories of functional decline in older adults with neuropsychiatric and cardiovascular multimorbidity: A Swedish cohort study.

PLoS Med 2018 03 6;15(3):e1002503. Epub 2018 Mar 6.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1002503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839531PMC
March 2018

The Nordic Prudent Diet Reduces Risk of Cognitive Decline in the Swedish Older Adults: A Population-Based Cohort Study.

Nutrients 2018 Feb 17;10(2). Epub 2018 Feb 17.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden.

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http://dx.doi.org/10.3390/nu10020229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852805PMC
February 2018

Risk Profiles for Injurious Falls in People Over 60: A Population-Based Cohort Study.

J Gerontol A Biol Sci Med Sci 2018 01;73(2):233-239

Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden.

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http://dx.doi.org/10.1093/gerona/glx115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861922PMC
January 2018

Personality and Survival in Older Age: The Role of Lifestyle Behaviors and Health Status.

Am J Geriatr Psychiatry 2017 Dec 8;25(12):1363-1372. Epub 2017 Jun 8.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Stress Research Institute, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jagp.2017.06.008DOI Listing
December 2017

Atrial fibrillation and use of antithrombotic medications in older people: A population-based study.

Int J Cardiol 2017 Dec;249:173-178

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.07.012DOI Listing
December 2017

Cardiovascular Risk Burden and Future Risk of Walking Speed Limitation in Older Adults.

J Am Geriatr Soc 2017 Nov;65(11):2418-2424

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jgs.15158DOI Listing
November 2017

Prevalence of depression: Comparisons of different depression definitions in population-based samples of older adults.

J Affect Disord 2017 10 13;221:123-131. Epub 2017 Jun 13.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Stress Research Institute, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jad.2017.06.011DOI Listing
October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Defining Health Trajectories in Older Adults With Five Clinical Indicators.

J Gerontol A Biol Sci Med Sci 2017 Aug;72(8):1123-1129

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, and Stockholm University, Sweden.

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http://dx.doi.org/10.1093/gerona/glw204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861965PMC
August 2017

Prevalence and Correlates of Olfactory Dysfunction in Old Age: A Population-Based Study.

J Gerontol A Biol Sci Med Sci 2017 Aug;72(8):1072-1079

Gösta Ekman's Laboratory, Department of Psychology, Stockholm University, Sweden.

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http://dx.doi.org/10.1093/gerona/glx054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861894PMC
August 2017

Anticholinergic drug use is associated with episodic memory decline in older adults without dementia.

Neurobiol Aging 2017 07 16;55:27-32. Epub 2017 Mar 16.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institute and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.03.009DOI Listing
July 2017

Influence of Negative Life Events and Widowhood on Risk for Dementia.

Am J Geriatr Psychiatry 2017 Jul 16;25(7):766-778. Epub 2017 Mar 16.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Psychology, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1016/j.jagp.2017.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474139PMC
July 2017

Cognitive performance in unipolar old-age depression: a longitudinal study.

Int J Geriatr Psychiatry 2017 06 1;32(6):675-684. Epub 2016 Jun 1.

Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1002/gps.4510DOI Listing
June 2017

Use of Medications of Questionable Benefit During the Last Year of Life of Older Adults With Dementia.

J Am Med Dir Assoc 2017 Jun 18;18(6):551.e1-551.e7. Epub 2017 Apr 18.

Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jamda.2017.02.021DOI Listing
June 2017

The changing prevalence and incidence of dementia over time - current evidence.

Nat Rev Neurol 2017 Jun 12;13(6):327-339. Epub 2017 May 12.

Department of Public Health and Primary Care, Cambridge Institute of Public Health, Forvie Site, University of Cambridge, School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK.

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http://dx.doi.org/10.1038/nrneurol.2017.63DOI Listing
June 2017

Cognitive and Physical Function in Relation to the Risk of Injurious Falls in Older Adults: A Population-Based Study.

J Gerontol A Biol Sci Med Sci 2017 May;72(5):669-675

Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1093/gerona/glw141DOI Listing
May 2017

Improving Public Awareness of Multimorbidity.

J Am Med Dir Assoc 2017 05 24;18(5):372-373. Epub 2017 Feb 24.

Department of Geriatrics, Centro Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1016/j.jamda.2017.01.010DOI Listing
May 2017

Living alone and unplanned hospitalizations among older adults: a population-based longitudinal study.

Eur J Public Health 2017 04;27(2):251-256

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1093/eurpub/ckw150DOI Listing
April 2017

Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study.

Alzheimers Dement 2017 Mar 10;13(3):247-256. Epub 2016 Aug 10.

Aging Research Center, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet-Stockholm University, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.06.2363DOI Listing
March 2017

Association of lifelong exposure to cognitive reserve-enhancing factors with dementia risk: A community-based cohort study.

PLoS Med 2017 03 14;14(3):e1002251. Epub 2017 Mar 14.

Aging Research Center, Department of Neurobiology, Caring Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1002251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349652PMC
March 2017

Trends in Incidence of Disability in Activities of Daily Living in Chinese Older Adults: 1993-2006.

J Am Geriatr Soc 2017 Feb 29;65(2):306-312. Epub 2016 Sep 29.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jgs.14468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310987PMC
February 2017

The economic burden of dementia in China, 1990-2030: implications for health policy.

Bull World Health Organ 2017 Jan 18;95(1):18-26. Epub 2016 Oct 18.

Ageing Research Centre, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm University, Gävlegatan 16, 113 30 Stockholm, Sweden .

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http://dx.doi.org/10.2471/BLT.15.167726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180346PMC
January 2017

Cost of Dementia and Its Correlation With Dependence.

J Aging Health 2016 12 9;28(8):1448-1464. Epub 2016 Jul 9.

1 Optum (now Mapi), Stockholm, Sweden.

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http://dx.doi.org/10.1177/0898264315624899DOI Listing
December 2016

Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75.

J Am Geriatr Soc 2016 12 2;64(12):2440-2447. Epub 2016 Nov 2.

Aging Research Center, Department Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jgs.14391DOI Listing
December 2016

Association of mobility limitations with incident disability among older adults: a population-based study.

Age Ageing 2016 11 28;45(6):812-819. Epub 2016 Apr 28.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1093/ageing/afw076DOI Listing
November 2016

Physical activity and inflammation: effects on gray-matter volume and cognitive decline in aging.

Hum Brain Mapp 2016 10 9;37(10):3462-73. Epub 2016 May 9.

Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1002/hbm.23252DOI Listing
October 2016

Effects of biological age on the associations of blood pressure with cardiovascular and non-cardiovascular mortality in old age: A population-based study.

Int J Cardiol 2016 Oct 24;220:508-13. Epub 2016 Jun 24.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.06.118DOI Listing
October 2016

Childhood school performance, education and occupational complexity: a life-course study of dementia in the Kungsholmen Project.

Int J Epidemiol 2016 08 10;45(4):1207-1215. Epub 2016 Mar 10.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/ije/dyw008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841626PMC
August 2016

Depression and Depression Treatment in a Population-Based Study of Individuals Over 60 Years Old Without Dementia.

Am J Geriatr Psychiatry 2016 08 29;24(8):615-623. Epub 2016 Mar 29.

Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Stockholm Gerontology Research Center, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jagp.2016.03.009DOI Listing
August 2016

Coexisting chronic conditions in the older population: Variation by health indicators.

Eur J Intern Med 2016 Jun 2;31:29-34. Epub 2016 Mar 2.

Aging Research Center, NVS Department, Karolinska Institutet, Sweden; Stockholm University, Sweden; Stockholm Gerontology Research Center, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ejim.2016.02.014DOI Listing
June 2016

Early Cognitive Deficits in Type 2 Diabetes: A Population-Based Study.

J Alzheimers Dis 2016 06;53(3):1069-78

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.3233/JAD-160266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981902PMC
June 2016

Multidimensional Prognostic Index in Association with Future Mortality and Number of Hospital Days in a Population-Based Sample of Older Adults: Results of the EU Funded MPI_AGE Project.

PLoS One 2015 29;10(7):e0133789. Epub 2015 Jul 29.

Aging Research Center, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet and Stockholm University, Stockholm, Sweden; Karolinska University Hospital, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133789PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519042PMC
May 2016

Three-year changes in leisure activities are associated with concurrent changes in white matter microstructure and perceptual speed in individuals aged 80 years and older.

Neurobiol Aging 2016 May 19;41:173-186. Epub 2016 Feb 19.

Aging Research Center, NVS Department, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.02.013DOI Listing
May 2016

Influence of Incipient Dementia on Hospitalization for Primary Care Sensitive Conditions: A Population-Based Cohort Study.

J Alzheimers Dis 2016 03;52(1):213-22

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.3233/JAD-150853DOI Listing
March 2016

Impact of living alone on institutionalization and mortality: a population-based longitudinal study.

Eur J Public Health 2016 Feb 27;26(1):182-7. Epub 2015 Mar 27.

1 Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1093/eurpub/ckv052DOI Listing
February 2016

Horizontal and vertical targeting: a population-based comparison of public eldercare services in urban and rural areas of Sweden.

Aging Clin Exp Res 2016 Feb 20;28(1):147-58. Epub 2015 May 20.

Division of Geriatric Medicine, Department of Health Sciences, Lund University and Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.1007/s40520-015-0369-5DOI Listing
February 2016

Prudent diet may attenuate the adverse effects of Western diet on cognitive decline.

Alzheimers Dement 2016 Feb 3;12(2):100-109. Epub 2015 Sep 3.

Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2015.08.002DOI Listing
February 2016

The impact of dementia on drug costs in older people: results from the SNAC study.

BMC Neurol 2016 Feb 29;16:28. Epub 2016 Feb 29.

Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12883-016-0547-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770687PMC
February 2016

Age-related variation in health status after age 60.

PLoS One 2015 3;10(3):e0120077. Epub 2015 Mar 3.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Stockholm Gerontology Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120077PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348523PMC
January 2016

Dementia in western Europe: epidemiological evidence and implications for policy making.

Lancet Neurol 2016 Jan 21;15(1):116-24. Epub 2015 Aug 21.

Department of Public Health and Primary Care, Cambridge Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(15)00092-7DOI Listing
January 2016

Statin Therapy and Dementia in Older Adults: Role of Disease Severity and Multimorbidity.

J Am Geriatr Soc 2016 Jan;64(1):223-4

Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jgs.13907DOI Listing
January 2016

Do levels of perceived stress increase with increasing age after age 65? A population-based study.

Age Ageing 2015 Sep 17;44(5):828-34. Epub 2015 Jul 17.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm 11330, Sweden.

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https://academic.oup.com/ageing/article-lookup/doi/10.1093/a
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http://dx.doi.org/10.1093/ageing/afv078DOI Listing
September 2015

HHEX_23 AA Genotype Exacerbates Effect of Diabetes on Dementia and Alzheimer Disease: A Population-Based Longitudinal Study.

PLoS Med 2015 Jul 14;12(7):e1001853. Epub 2015 Jul 14.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Stockholm Gerontology Research Center, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1001853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501827PMC
July 2015

Natural-cause mortality and long-term exposure to particle components: an analysis of 19 European cohorts within the multi-center ESCAPE project.

Environ Health Perspect 2015 Jun 24;123(6):525-33. Epub 2015 Feb 24.

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1289/ehp.1408095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455583PMC
June 2015

Effects of vascular risk factors and APOE ε4 on white matter integrity and cognitive decline.

Neurology 2015 Mar 11;84(11):1128-35. Epub 2015 Feb 11.

From the Aging Research Center (R.W., L.F., E.J.L., M.L., G.K., L.K., A.S., L.B., C.Q.), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University; Stockholm Gerontology Research Center (L.F., L.B.); and Division of Neurogeriatrics (C.G.), Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Center for Alzheimer Research at Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000001379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371409PMC
March 2015