Publications by authors named "Laura Flores-Sarnat"

56Publications

Sarnat Grading Scale for Neonatal Encephalopathy after 45 Years: An Update Proposal.

Pediatr Neurol 2020 Aug 27;113:75-79. Epub 2020 Aug 27.

Section of Neonatology, Department of Paediatrics, University of Calgary Cumming School of Medicine and Alberta Children's Hospital Research Institute (Owerko Centre), Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.pediatrneurol.2020.08.014DOI Listing
August 2020

Survey on Olfactory Testing by Pediatric Neurologists: Is the Olfactory a "True" Cranial Nerve?

J Child Neurol 2020 Apr 8;35(5):317-321. Epub 2020 Jan 8.

Departments of Paediatrics, Clinical Neurosciences, University of Calgary Cumming School of Medicine and Alberta Children's Hospital Research Institute (Owerko Centre), Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/0883073819896513DOI Listing
April 2020

Development of the human olfactory system.

Handb Clin Neurol 2019 ;164:29-45

Department of Paediatrics, University of Calgary Cumming School of Medicine and Alberta Children's Hospital Research Institute, Calgary, AB, Canada; Department of Clinical Neurosciences, University of Calgary Cumming School of Medicine and Alberta Children's Hospital Research Institute, Calgary, AB, Canada.

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http://dx.doi.org/10.1016/B978-0-444-63855-7.00003-4DOI Listing
March 2020

Area Postrema: Fetal Maturation, Tumors, Vomiting Center, Growth, Role in Neuromyelitis Optica.

Pediatr Neurol 2019 05 25;94:21-31. Epub 2018 Dec 25.

Department of Paediatric Neurology, Children's University Hospital, Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.pediatrneurol.2018.12.006DOI Listing
May 2019

mTOR Inhibitors as a New Therapeutic Strategy in Treatment Resistant Epilepsy in Hemimegalencephaly: A Case Report.

J Child Neurol 2019 03 5;34(3):132-138. Epub 2018 Dec 5.

1 Division of Neurology, University of British Columbia, BC Children's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1177/0883073818813238DOI Listing
March 2019

Olfactory Development, Part 1: Function, From Fetal Perception to Adult Wine-Tasting.

J Child Neurol 2017 05 19;32(6):566-578. Epub 2017 Feb 19.

4 Department of Radiology and Diagnostic Imaging, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/0883073817690867DOI Listing
May 2017

Olfactory Development, Part 2: Neuroanatomic Maturation and Dysgeneses.

J Child Neurol 2017 05 19;32(6):579-593. Epub 2017 Feb 19.

1 Department of Paediatrics, University of Calgary and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/0883073816685192DOI Listing
May 2017

Might the olfactory bulb be an origin of olfactory auras in focal epilepsy?

Epileptic Disord 2016 Dec;18(4):344-355

Departments of Paediatrics, and Clinical Neurosciences, University of Calgary Cumming School of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1684/epd.2016.0869DOI Listing
December 2016

Telencephalic Flexure and Malformations of the Lateral Cerebral (Sylvian) Fissure.

Pediatr Neurol 2016 10 10;63:23-38. Epub 2016 May 10.

Department of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.pediatrneurol.2016.05.005DOI Listing
October 2016

Synaptogenesis and Myelination in the Nucleus/Tractus Solitarius: Potential Role in Apnea of Prematurity, Congenital Central Hypoventilation, and Sudden Infant Death Syndrome.

J Child Neurol 2016 May 10;31(6):722-32. Epub 2015 Dec 10.

Departments of Paediatrics, Pathology (Neuropathology) and Clinical Neurosciences, University of Calgary and Alberta Children's Hospital Research Institute, Calgary Alberta, Canada.

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http://dx.doi.org/10.1177/0883073815615227DOI Listing
May 2016

Phenotype/genotype correlations in epidermal nevus syndrome as a neurocristopathy.

Handb Clin Neurol 2015 ;132:9-25

Departments of Paediatrics, Pathology (Neuropathology) and Clinical Neurosciences, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/B978-0-444-62702-5.00002-0DOI Listing
August 2016

Timing in neural maturation: arrest, delay, precociousness, and temporal determination of malformations.

Pediatr Neurol 2015 May 9;52(5):473-86. Epub 2015 Feb 9.

Department of Paediatrics, University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada; Department of Radiology and Diagnostic Imaging, University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.pediatrneurol.2015.01.020DOI Listing
May 2015

Infantile tauopathies: Hemimegalencephaly; tuberous sclerosis complex; focal cortical dysplasia 2; ganglioglioma.

Brain Dev 2015 Jun 19;37(6):553-62. Epub 2014 Oct 19.

Department of Paediatrics, University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Foundation, Calgary, Alberta, Canada; Department of Clinical Neurosciences, University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Foundation, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.braindev.2014.08.010DOI Listing
June 2015

Morphogenesis timing of genetically programmed brain malformations in relation to epilepsy.

Prog Brain Res 2014 ;213:181-98

Department of Paediatrics, Faculty of Medicine and Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada; Department of Clinical Neurosciences, Faculty of Medicine and Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/B978-0-444-63326-2.00010-7DOI Listing
April 2015

Precocious synapses in 13.5-week fetal holoprosencephalic cortex and cyclopean retina.

Brain Dev 2014 Jun 14;36(6):463-71. Epub 2014 Feb 14.

Department of Pathology (Paediatric), University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.braindev.2014.01.008DOI Listing
June 2014

Synaptogenesis in the foetal and neonatal cerebellar system. 2. Pontine nuclei and cerebellar cortex.

Dev Neurosci 2013 20;35(4):317-25. Epub 2013 Jun 20.

Departments of Paediatrics, Pathology (Neuropathology) and Clinical Neurosciences (Neurology and Neurosurgery), University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alta., Canada.

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http://dx.doi.org/10.1159/000351031DOI Listing
March 2014

Sequence of synaptogenesis in the fetal and neonatal cerebellar system - part 1: Guillain-Mollaret triangle (dentato-rubro-olivo-cerebellar circuit).

Dev Neurosci 2013 18;35(1):69-81. Epub 2013 May 18.

Department of Paediatrics, University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alta., Canada.

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http://dx.doi.org/10.1159/000350503DOI Listing
December 2013

Neuropathology of pediatric epilepsy.

Handb Clin Neurol 2013 ;111:399-416

Departments of Clinical Neurosciences and Paediatrics, Division of Paediatric Neurology, University of Calgary, Alberta Children's Hospital, Calgary, Canada. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-52891-9.00044-0DOI Listing
April 2014

Neurocutaneous melanocytosis.

Handb Clin Neurol 2013 ;111:369-88

Departments of Clinical Neurosciences and Paediatrics, Division of Paediatric Neurology, University of Calgary, Alberta Children's Hospital, Calgary, Canada. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-52891-9.00042-7DOI Listing
April 2014

Epidermal nevus syndrome.

Handb Clin Neurol 2013 ;111:349-68

Departments of Clinical Neurosciences and Paediatrics, Division of Paediatric Neurology, University of Calgary, Alberta Children's Hospital, Calgary, Canada. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-52891-9.00041-5DOI Listing
April 2014

Genetics of neural crest and neurocutaneous syndromes.

Handb Clin Neurol 2013 ;111:309-14

Departments of Clinical Neurosciences and Paediatrics, Division of Paediatric Neurology, University of Calgary, Alberta Children's Hospital, Calgary, Canada.

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http://dx.doi.org/10.1016/B978-0-444-52891-9.00036-1DOI Listing
April 2014

Neuroembryology and brain malformations: an overview.

Handb Clin Neurol 2013 ;111:117-28

Departments of Clinical Neurosciences and Paediatrics, Division of Paediatric Neurology, University of Calgary, Alberta Children's Hospital, Calgary, Canada. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-52891-9.00012-9DOI Listing
April 2014

Radial microcolumnar cortical architecture: maturational arrest or cortical dysplasia?

Pediatr Neurol 2013 Apr;48(4):259-70

Department of Paediatrics (Neurology), University of Calgary Faculty of Medicine and Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.pediatrneurol.2012.10.001DOI Listing
April 2013

Precocious and delayed neocortical synaptogenesis in fetal holoprosencephaly.

Clin Neuropathol 2013 Jul-Aug;32(4):255-68

Department of Paediatrics, University of Calgary Faculty of Medicine and Alberta Children's Hospital, Calgary Research Institute, Calgary, Alberta, Canada.

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http://dx.doi.org/10.5414/NP300588DOI Listing
September 2013

Hemimegalencephaly: foetal tauopathy with mTOR hyperactivation and neuronal lipidosis.

Folia Neuropathol 2012 ;50(4):330-45

University of Calgary and Alberta Children's Hospital Calgary, Alberta, Canada.

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http://dx.doi.org/10.5114/fn.2012.32363DOI Listing
November 2013

Endothelial ultrastructural alterations of intramuscular capillaries in infantile mitochondrial cytopathies: "mitochondrial angiopathy".

Neuropathology 2012 Dec 12;32(6):617-27. Epub 2012 Mar 12.

Department of Paediatrics, University of Calgary Faculty of Medicine and Alberta Children's Hospital, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1440-1789.2012.01308.xDOI Listing
December 2012

Congenital infiltrating lipomatosis of the face: recognition and pathogenesis.

Neuropediatrics 2012 Dec 5;43(6):346-8. Epub 2012 Nov 5.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0032-1330853
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http://dx.doi.org/10.1055/s-0032-1330853DOI Listing
December 2012

Fetal brain mTOR signaling activation in tuberous sclerosis complex.

Cereb Cortex 2014 Feb 18;24(2):315-27. Epub 2012 Oct 18.

PENN Epilepsy Center, Department of Neurology and University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/cercor/bhs310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888364PMC
February 2014

Synaptogenesis in the fetal corpus striatum, globus pallidus, and substantia nigra: correlations with striosomes of Graybiel and dyskinesias in premature infants.

J Child Neurol 2013 Jan 24;28(1):60-9. Epub 2012 Apr 24.

Departments of Paediatrics, Pathology (Neuropathology), and Clinical Neurosciences, University of Calgary Faculty of Medicine and Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/0883073812439752DOI Listing
January 2013

Mitochondrial "hypermetabolic" neurons in paediatric epileptic foci.

Can J Neurol Sci 2011 Nov;38(6):909-17

Department of Paediatrics, University of Calgary Faculty of Medicine and Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1017/s0317167100012518DOI Listing
November 2011

Fetal opercular cavernous angioma causing cerebral cleft: contralateral primitive vascular anomaly and subicular dysgenesis.

J Child Neurol 2012 Apr 3;27(4):478-84. Epub 2011 Oct 3.

Department of Paediatrics (Neurology), University of Calgary Faculty of Medicine and Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://journals.sagepub.com/doi/10.1177/0883073811420293
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http://dx.doi.org/10.1177/0883073811420293DOI Listing
April 2012

Synaptophysin immunoreactivity in the human hippocampus and neocortex from 6 to 41 weeks of gestation.

J Neuropathol Exp Neurol 2010 Mar;69(3):234-45

Departments of Paediatrics, Pathology (Neuropathology), and Clinical Neurosciences, University of Calgary Faculty of Medicine and Alberta Children's Hospital, Alberta, Canada.

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http://dx.doi.org/10.1097/NEN.0b013e3181d0151fDOI Listing
March 2010

Alpha-B-crystallin as a tissue marker of epileptic foci in paediatric resections.

Can J Neurol Sci 2009 Sep;36(5):566-74

Department of Paediatrics, Alberta Children's Hospital and University of Calgary Faculty of Medicine, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1017/s0317167100008052DOI Listing
September 2009

Hemimegalencephaly syndrome.

Handb Clin Neurol 2008 ;87:153-76

Division of Pediatric Neurology, Alberta Children's Hospital, 1888 Shaganappi Trail NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/S0072-9752(07)87010-2DOI Listing
December 2010

Axes and gradients of the neural tube for a morphological/molecular genetic classification of nervous system malformations.

Handb Clin Neurol 2008 ;87:1-11

Division of Pediatric Neurology, Alberta Children's Hospital, 1888 Shaganappi Trail NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/S0072-9752(07)87001-1DOI Listing
December 2010

Plasma glucose concentrations in profound neonatal hypoglycemia.

Clin Pediatr (Phila) 2006 Jul;45(6):550-8

Division of Neonatology, Department of Pediatrics, Ahmanson Pediatric Center, David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USA, and Division of Neurology, Department of Pediatrics, Alberta Children's Hospital, Calgary, Canada.

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http://dx.doi.org/10.1177/0009922806290610DOI Listing
July 2006

Cerebral palsy due to chromosomal anomalies and continuous gene syndromes.

Clin Perinatol 2006 Jun;33(2):481-501

Division of Pediatric Neurology, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1016/j.clp.2006.03.001DOI Listing
June 2006

Population meta-analysis of low plasma glucose thresholds in full-term normal newborns.

Am J Perinatol 2006 Feb;23(2):115-9

Division of Neonatology, Department of Pediatrics, Ahmanson Pediatric Center, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

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http://dx.doi.org/10.1055/s-2006-931912DOI Listing
February 2006

Deletion of chromosome 21 disturbs human brain morphogenesis.

Genet Med 2006 Jan;8(1):1-7

Division of Medical Genetics, Department of Pediatrics, Cedars-Sinai Health System and Department of Human Genetics, University of California at Los Angeles, CA, USA.

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http://dx.doi.org/10.1097/01.gim.0000195892.60506.3fDOI Listing
January 2006

Brain imaging findings in neonatal hypoglycemia: case report and review of 23 cases.

Clin Pediatr (Phila) 2005 Nov-Dec;44(9):783-90

Division of Neonatology, Department of Pediatrics, Ahmanson Pediatric Center, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1177/000992280504400906DOI Listing
March 2006

Embryology of the neural crest: its inductive role in the neurocutaneous syndromes.

J Child Neurol 2005 Aug;20(8):637-43

Department of Pediatrics (Neurology), University of Calgary, Faculty of Medicine, Alberta Children's Hospital, Calgary, AB, Canada.

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http://dx.doi.org/10.1177/08830738050200080101DOI Listing
August 2005

Neurologic aspects of neonatal hypoglycemia.

Isr Med Assoc J 2005 Mar;7(3):188-92

Division of Neonatology , Department of Pediatrics, Ahmanson Pediatric Center, Cedars-Sinai Medical Center, Los Angeles 90048, USA.

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March 2005

Integrative classification of morphology and molecular genetics in central nervous system malformations.

Am J Med Genet A 2004 May;126A(4):386-92

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California 90048, USA.

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http://dx.doi.org/10.1002/ajmg.a.20663DOI Listing
May 2004

Hemimegalencephaly: part 2. Neuropathology suggests a disorder of cellular lineage.

J Child Neurol 2003 Nov;18(11):776-85

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1177/08830738030180111101DOI Listing
November 2003

Etiological classification of CNS malformations: integration of molecular genetic and morphological criteria.

Epileptic Disord 2003 Sep;5 Suppl 2:S35-43

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center and University of California School of Medicine at Los Angeles (UCLA), Los Angeles, CA 90048, USA.

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September 2003

Molecular genetic and morphologic integration in malformations of the nervous system for etiologic classification.

Semin Pediatr Neurol 2002 Dec;9(4):335-44

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center and University of California School of Medicine at Los Angeles (UCLA), Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1053/spen.2002.32509DOI Listing
December 2002

Role of Cajal-Retzius and subplate neurons in cerebral cortical development.

Semin Pediatr Neurol 2002 Dec;9(4):302-8

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1053/spen.2002.32506DOI Listing
December 2002

New insights into craniosynostosis.

Semin Pediatr Neurol 2002 Dec;9(4):274-91

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1053/spen.2002.32504DOI Listing
December 2002

Severe mitochondrial cytopathy with complete A-V block, PEO, and mtDNA deletions.

Pediatr Neurol 2002 Sep;27(3):213-6

Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey 08904, USA.

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http://dx.doi.org/10.1016/s0887-8994(02)00426-5DOI Listing
September 2002

Lobar holoprosencephaly.

J Child Neurol 2002 Jul;17(7):543; author reply 543-4

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http://dx.doi.org/10.1177/088307380201700715DOI Listing
July 2002

Hemimegalencephaly: part 1. Genetic, clinical, and imaging aspects.

J Child Neurol 2002 May;17(5):373-84; discussion 384

Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1177/088307380201700512DOI Listing
May 2002

Cajal-Retzius and subplate neurons: their role in cortical development.

Eur J Paediatr Neurol 2002 ;6(2):91-7

Department of Pediatrics (Neurology), Cedars-Sinai Medical Center, Los Angeles, California 90043, USA.

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http://dx.doi.org/10.1053/ejpn.2001.0554DOI Listing
October 2002