Laura A Cleghorn

Laura A T Cleghorn

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Laura A Cleghorn

Laura A T Cleghorn

Publications by authors named "Laura A T Cleghorn"

14Publications

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1PubMed Central Citations

Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome Oxidase in ".

Antimicrob Agents Chemother 2017 09 24;61(9). Epub 2017 Aug 24.

Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1128/AAC.01429-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571366PMC
September 2017

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei.

J Med Chem 2015 Oct 29;58(19):7695-706. Epub 2015 Sep 29.

Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee , Sir James Black Centre, Dundee, DD1 5EH, U.K.

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http://dx.doi.org/10.1021/acs.jmedchem.5b00596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601051PMC
October 2015

Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.

Antimicrob Agents Chemother 2014 Nov 25;58(11):6962-5. Epub 2014 Aug 25.

Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/AAC.03486-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249445PMC
November 2014

From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules.

ChemMedChem 2013 Jul 14;8(7):1127-37. Epub 2013 Jun 14.

Drug Discovery Unit (DDU), Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Sir James Black Centre, DD1 5EH, UK.

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http://dx.doi.org/10.1002/cmdc.201300072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728731PMC
July 2013

Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3.

ChemMedChem 2011 Dec 13;6(12):2214-24. Epub 2011 Sep 13.

Drug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee, DD1 5EH, UK.

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http://dx.doi.org/10.1002/cmdc.201100344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272345PMC
December 2011

Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488.

ChemMedChem 2011 Oct 10;6(10):1832-40. Epub 2011 Aug 10.

Drug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee, DD1 5EH, Scotland, UK.

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http://dx.doi.org/10.1002/cmdc.201100278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229842PMC
October 2011

Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.

ChemMedChem 2009 Dec;4(12):2060-9

Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee, DD1 5EH, UK.

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http://dx.doi.org/10.1002/cmdc.200900262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855869PMC
December 2009

Bimetallic catalytic synthesis of annelated benzazepines.

Chem Commun (Camb) 2005 Jun 11(24):3071-3. Epub 2005 May 11.

Molecular Innovation, Diversity and Automated Synthesis (MIDAS) Centre, School of Chemistry, Leeds University, Leeds, UKLS2 9JT.

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http://dx.doi.org/10.1039/b503213jDOI Listing
June 2005