Laura A Nguyen

Laura A Nguyen

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Laura A Nguyen

Laura A Nguyen

Publications by authors named "Laura A Nguyen"

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14Publications

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Crystal structure of Pistol, a class of self-cleaving ribozyme.

Proc Natl Acad Sci U S A 2017 01 17;114(5):1021-1026. Epub 2017 Jan 17.

Department of Molecular Biochemistry and Biophysics, Yale University, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1611191114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293083PMC
January 2017

Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template.

Antiviral Res 2015 Mar 31;115:75-82. Epub 2014 Dec 31.

Center for Drug Discovery, Emory Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2014.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323949PMC
March 2015

SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.

PLoS One 2014 19;9(2):e89558. Epub 2014 Feb 19.

Department of Microbiology, NYU School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089558PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929709PMC
October 2014

Host SAMHD1 protein promotes HIV-1 recombination in macrophages.

J Biol Chem 2014 Jan 18;289(5):2489-96. Epub 2013 Dec 18.

From the Departments of Pathology and Laboratory Medicine and.

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http://dx.doi.org/10.1074/jbc.C113.522326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908385PMC
January 2014

Effect of ribonucleotides embedded in a DNA template on HIV-1 reverse transcription kinetics and fidelity.

J Biol Chem 2013 May 11;288(18):12522-32. Epub 2013 Mar 11.

Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M113.458398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642300PMC
May 2013

Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages.

J Biol Chem 2012 Jun 14;287(26):21570-4. Epub 2012 May 14.

Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.C112.374843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381122PMC
June 2012

HIV-1 reverse transcriptase dissociates during strand transfer.

J Mol Biol 2011 Sep 29;412(3):354-64. Epub 2011 Jul 29.

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1016/j.jmb.2011.07.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166975PMC
September 2011