Publications by authors named "Laura A Johnson"

73Publications

AXL Is a Potential Target for the Treatment of Intestinal Fibrosis.

Inflamm Bowel Dis 2020 Jul 17. Epub 2020 Jul 17.

Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1093/ibd/izaa169DOI Listing
July 2020

Prevalence and Effect of Intestinal Infections Detected by a PCR-Based Stool Test in Patients with Inflammatory Bowel Disease.

Dig Dis Sci 2020 Nov 24;65(11):3287-3296. Epub 2020 Jan 24.

Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/s10620-020-06071-2DOI Listing
November 2020

Strain-Photoacoustic Imaging as a Potential Tool for Characterizing Intestinal Fibrosis.

Gastroenterology 2019 11 13;157(5):1196-1198. Epub 2019 Aug 13.

Department of Radiology, University of Michigan Medical School, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.07.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815724PMC
November 2019

Characterizing intestinal strictures of Crohn's disease by endoscopic photoacoustic imaging.

Biomed Opt Express 2019 May 24;10(5):2542-2555. Epub 2019 Apr 24.

Department of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1364/BOE.10.002542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524586PMC
May 2019

Identifying intestinal fibrosis and inflammation by spectroscopic photoacoustic imaging: an animal study .

Biomed Opt Express 2018 Apr 8;9(4):1590-1600. Epub 2018 Mar 8.

Department of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1364/BOE.9.001590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905908PMC
April 2018

Molecular imaging biomarkers for cell-based immunotherapies.

J Transl Med 2017 06 19;15(1):140. Epub 2017 Jun 19.

Center for Magnetic Resonance and Optical Imaging (CMROI), Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, B1 Stellar-Chance Laboratories, 422 Curie Boulevard, Philadelphia, PA, 19104-6100, USA.

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http://dx.doi.org/10.1186/s12967-017-1240-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477274PMC
June 2017

Can Contrast-Enhanced Sonography Detect Bowel Wall Fibrosis in Mixed Inflammatory and Fibrotic Crohn Disease Lesions in an Animal Model?

J Ultrasound Med 2017 Mar 10;36(3):523-530. Epub 2017 Jan 10.

Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.7863/ultra.16.04064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557400PMC
March 2017

Driving gene-engineered T cell immunotherapy of cancer.

Cell Res 2017 Jan 27;27(1):38-58. Epub 2016 Dec 27.

Center for Cellular Immunotherapies, Perelman School of Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/cr.2016.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223234PMC
January 2017

Characterizing intestinal inflammation and fibrosis in Crohn's disease by photoacoustic imaging: feasibility study.

Biomed Opt Express 2016 Jul 27;7(7):2837-48. Epub 2016 Jun 27.

Department of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1364/BOE.7.002837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948634PMC
July 2016

Intestinal organoids: a model of intestinal fibrosis for evaluating anti-fibrotic drugs.

Exp Mol Pathol 2015 Jun 28;98(3):346-51. Epub 2015 Mar 28.

Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2015.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915372PMC
June 2015

Chimeric antigen receptor engineered T cells can eliminate brain tumors and initiate long-term protection against recurrence.

Oncoimmunology 2014;3(7):e944059. Epub 2014 Jul 3.

Duke Brain Tumor Immunotherapy Program; Division of Neurosurgery; Department of Surgery; Duke University Medical Center ; Durham, NC USA.

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http://www.tandfonline.com/doi/abs/10.4161/21624011.2014.944
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http://dx.doi.org/10.4161/21624011.2014.944059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292711PMC
July 2014

Comparison of noncontrast MRI magnetization transfer and T2 -Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model.

J Magn Reson Imaging 2015 Sep 13;42(3):801-10. Epub 2014 Dec 13.

Division of Gastroenterology, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1002/jmri.24815DOI Listing
September 2015

Ultrasound shear wave elastography helps discriminate low-grade from high-grade bowel wall fibrosis in ex vivo human intestinal specimens.

J Ultrasound Med 2014 Dec;33(12):2115-23

Departments of Radiology (J.R.D., J.M.R.), Internal Medicine, Division of Gastroenterology (R.W.S., P.D.R.H., L.A.J.), and Pathology (D.S.M.), University of Michigan Health System, Ann Arbor, Michigan USA; and Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, Michigan USA (N.R.K.).

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http://dx.doi.org/10.7863/ultra.33.12.2115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511264PMC
December 2014

Specific increase in potency via structure-based design of a TCR.

J Immunol 2014 Sep 28;193(5):2587-99. Epub 2014 Jul 28.

Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016; Program in Structural Biology, New York University School of Medicine, New York, NY 10016; Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine, New York, NY 10016

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http://dx.doi.org/10.4049/jimmunol.1302344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205480PMC
September 2014

Engineered T cells for cancer therapy.

Cancer Immunol Immunother 2014 Sep 19;63(9):969-75. Epub 2014 Jun 19.

Abramson Cancer Center, University of Pennsylvania, 3400 Civic Center Boulevard, 8th Floor, Philadelphia, PA, 19104-5156, USA,

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http://dx.doi.org/10.1007/s00262-014-1568-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142345PMC
September 2014

EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma.

PLoS One 2014 10;9(4):e94281. Epub 2014 Apr 10.

Duke Brain Tumor Immunotherapy Program, Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America; Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094281PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983153PMC
January 2015

EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.

Clin Cancer Res 2014 Feb 18;20(4):972-84. Epub 2013 Dec 18.

Authors' Affiliations: Duke Brain Tumor Immunotherapy Program, Division of Neurosurgery, Department of Surgery; Department of Pathology; The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center; Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina; and Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943170PMC
February 2014

Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts.

Inflamm Bowel Dis 2014 Jan;20(1):154-65

*Department of Internal Medicine, †Department of Pharmacology, and ‡Vahlteich Medicinal Chemistry Core, College of Pharmacy, University of Michigan, Ann Arbor, Michigan.

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http://pdfs.journals.lww.com/ibdjournal/2014/01000/Novel_Rho
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/01.MIB.0000437615.98881.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893808PMC
January 2014

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.

Nature 2013 Dec 3;504(7478):138-42. Epub 2013 Nov 3.

1] The Broad Institute of Harvard University and Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature12688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098832PMC
December 2013

2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.

Eur J Immunol 2014 Jan 20;44(1):239-50. Epub 2013 Oct 20.

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

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http://dx.doi.org/10.1002/eji.201343774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941036PMC
January 2014

Antibody, T-cell and dendritic cell immunotherapy for malignant brain tumors.

Future Oncol 2013 Jul;9(7):977-90

Duke University Medical Center, Department of Pathology, Durham, NC 27710, USA.

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http://dx.doi.org/10.2217/fon.13.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904373PMC
July 2013

Interactive effects of pesticide mixtures, predators, and environmental regimes on the toxicity of two pesticides to red-eyed tree frog larvae.

Environ Toxicol Chem 2013 Oct 21;32(10):2379-86. Epub 2013 Aug 21.

Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, North Carolina, USA.

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http://dx.doi.org/10.1002/etc.2319DOI Listing
October 2013

Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.

PLoS One 2013 18;8(3):e59082. Epub 2013 Mar 18.

Duke Brain Tumor Immunotherapy Program, Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059082PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601076PMC
September 2013

Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts.

Inflamm Bowel Dis 2013 Apr;19(5):891-903

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109-5682, USA.

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http://dx.doi.org/10.1097/MIB.0b013e3182813297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766259PMC
April 2013

Engineering improved T cell receptors using an alanine-scan guided T cell display selection system.

J Immunol Methods 2013 Jun 13;392(1-2):1-11. Epub 2013 Mar 13.

NYU Cancer institute, New York University School of Medicine, NewYork, NY 10016, USA.

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http://dx.doi.org/10.1016/j.jim.2013.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668434PMC
June 2013

US elastography-derived shear wave velocity helps distinguish acutely inflamed from fibrotic bowel in a Crohn disease animal model.

Radiology 2013 Jun 11;267(3):757-66. Epub 2013 Feb 11.

Department of Radiology, Section of Pediatric Radiology, University of Michigan Health System, C.S. Mott Children's Hospital, 1540 E Hospital Dr, Ann Arbor, MI 48109-4252, USA.

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http://dx.doi.org/10.1148/radiol.13121775DOI Listing
June 2013

Model T muscle CARs can treat brain tumors.

Authors:
Laura A Johnson

Clin Cancer Res 2012 Nov 27;18(21):5834-6. Epub 2012 Sep 27.

Brain Tumor Immunotherapy Program, Neurosurgery Division, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-12-2627DOI Listing
November 2012

CARD-024, a vitamin D analog, attenuates the pro-fibrotic response to substrate stiffness in colonic myofibroblasts.

Exp Mol Pathol 2012 Aug 18;93(1):91-8. Epub 2012 Apr 18.

University of Michigan, Department of Internal Medicine, Ann Arbor, MI 48109-0682, United States.

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http://dx.doi.org/10.1016/j.yexmp.2012.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443252PMC
August 2012

A new nonlinear parameter in the developed strain-to-applied strain of the soft tissues and its application in ultrasound elasticity imaging.

Ultrasound Med Biol 2012 Mar 21;38(3):511-23. Epub 2012 Jan 21.

Center for Ultrasound Molecular Imaging and Therapeutics, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S030156291101541
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http://dx.doi.org/10.1016/j.ultrasmedbio.2011.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273568PMC
March 2012

Spironolactone and colitis: increased mortality in rodents and in humans.

Inflamm Bowel Dis 2012 Jul 13;18(7):1315-24. Epub 2011 Nov 13.

University of Michigan, Department of Internal Medicine, Ann Arbor, Michigan 48109-0682, USA.

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http://dx.doi.org/10.1002/ibd.21929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288762PMC
July 2012

Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice.

Inflamm Bowel Dis 2012 Mar 14;18(3):460-71. Epub 2011 Jul 14.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Hospitals, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1002/ibd.21812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206985PMC
March 2012

Prior Helicobacter pylori infection ameliorates Salmonella typhimurium-induced colitis: mucosal crosstalk between stomach and distal intestine.

Inflamm Bowel Dis 2011 Jun 25;17(6):1398-408. Epub 2010 Oct 25.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Hospitals, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1002/ibd.21489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466047PMC
June 2011

A randomised trial of sheathed versus standard forceps for obtaining uncontaminated biopsy specimens of microbiota from the terminal ileum.

Gut 2011 Aug 11;60(8):1043-9. Epub 2011 Feb 11.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Medical Center, Medical Science Research Ann Arbor, MI 48109-0682, USA.

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http://dx.doi.org/10.1136/gut.2010.224337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244887PMC
August 2011

Transient or persistent norovirus infection does not alter the pathology of Salmonella typhimurium induced intestinal inflammation and fibrosis in mice.

Comp Immunol Microbiol Infect Dis 2011 May 14;34(3):247-57. Epub 2011 Jan 14.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Medical Center, Medical Science Research Building One, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5682, United States.

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http://dx.doi.org/10.1016/j.cimid.2010.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167145PMC
May 2011

Immunotherapy approaches for malignant glioma from 2007 to 2009.

Curr Neurol Neurosci Rep 2010 Jul;10(4):259-66

Duke Brain Tumor Immunotherapy Program, Preston Robert Tisch Brain Tumor Center, Division of Neurosurgery, Department of Surgery, Duke University Medical Center, DUMC 3050, Sands Research Building, Durham, NC 27710, USA.

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http://dx.doi.org/10.1007/s11910-010-0111-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412398PMC
July 2010

An oncogenic role for ETV1 in melanoma.

Cancer Res 2010 Mar 16;70(5):2075-84. Epub 2010 Feb 16.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846410PMC
March 2010

Noninvasive ultrasound elasticity imaging (UEI) of Crohn's disease: animal model.

Ultrasound Med Biol 2008 Jun 21;34(6):902-12. Epub 2008 Feb 21.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2007.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157329PMC
June 2008

Single cell electrophoresis in determining cell death: potential for use in organ transplant research.

J Biochem Biophys Methods 2005 Apr 8;63(1):53-68. Epub 2005 Mar 8.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.jbbm.2005.02.002DOI Listing
April 2005

Analysis of postmortem DNA degradation by single-cell gel electrophoresis.

Forensic Sci Int 2002 Mar;126(1):43-7

Department of Pathology and Laboratory of Medicine, Vancouver General Hospital Site, Research Pavilion, University of British Columbia, BC, Vancouver, Canada.

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http://dx.doi.org/10.1016/s0379-0738(02)00027-0DOI Listing
March 2002